Inhibition of the antigen-induced activation of rodent mast cells by putative Janus kinase 3 inhibitors WHI-P131 and WHI-P154 in a Janus kinase 3-independent manner

British Journal of Pharmacology

Volumn 145, Issue 6, 2005, Pages 818-828

  Linwong, Watchara ^a   Hirasawa, Noriyasu ^a   Aoyama, Suzue ^a   Hamada, Hirofumi ^b   Saito, Takashi ^c   Ohuchi, Kazuo ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b SAPPORO MEDICAL UNIVERSITY   (Japan)

^c Institute of Physical and Chemical Research   (Japan)

Author keywords

c Jun N terminal kinase; Fyn; Mast cells; p38 MAP kinase; p44 42 MAP kinase; Phosphatidylinositol 3 kinase; WHI P131; WHI P154

Indexed keywords

4 (3 BROMO 4 HYDROXYANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 (3' BROMO 4' HYDROXYPHENYL)AMINO 6,7 DIMETHOXYQUINAZOLINE; 4 (4 HYDROXYANILINO) 6,7 DIMETHOXYQUINAZOLINE; ADAPTOR PROTEIN; ANTIGEN; BRUTON TYROSINE KINASE; IMMUNOGLOBULIN E; INTERLEUKIN 3; JANUS KINASE 3; JANUS KINASE 3 INHIBITOR; LAT PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN GAB2; PROTEIN KINASE B; PROTEIN KINASE FYN; RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; VAV PROTEIN;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; IMMUNOPRECIPITATION; MAST CELL DEGRANULATION; MAST CELL LEUKEMIA; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL CYCLE PROTEINS; CELL DEGRANULATION; CELL LINE, TUMOR; DINITROPHENOLS; HEXOSAMINIDASES; IMMUNOGLOBULIN E; JANUS KINASE 3; MAST CELLS; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-FYN; PROTO-ONCOGENE PROTEINS C-VAV; QUINAZOLINES; RATS; SERUM ALBUMIN; SRC-FAMILY KINASES;

EID: 23044457848     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706240     Document Type: Article

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