Targeting Janus kinase 3 in mast cells prevents immediate hypersensitivity reactions and anaphylaxis

Journal of Biological Chemistry

Volumn 274, Issue 38, 1999, Pages 27028-27033

  Malaviya, Ravi ^a   Zhu, DeMin ^a   Dibirdik, Ilker ^a   Uckun, Fatih M ^a  

^a PARKER HUGHES INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 HYDROXYANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 (4' HYDROXYPHENYL)AMINO 6,7 DIMETHOXYQUINAZOLINE; IMMUNOGLOBULIN E RECEPTOR; MICROTUBULE ASSOCIATED PROTEIN; PHOSPHOLIPASE C; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; UNCLASSIFIED DRUG;

ALLERGIC REACTION; ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM MOBILIZATION; CONTROLLED STUDY; DEGRANULATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HYPERSENSITIVITY; MALE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANAPHYLAXIS; ANIMALS; CALCIUM; CELL LINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; HUMANS; HYPERSENSITIVITY, IMMEDIATE; JANUS KINASE 3; MALE; MAST CELLS; MICE; MICE, INBRED BALB C; PROTEIN-TYROSINE KINASES; QUINAZOLINES; RECEPTORS, IGE;

EID: 0033578618     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.38.27028     Document Type: Article

References (53)

1. Galli, S. J. (1993) N. Engl. J. Med. 328, 257-265
2. Gordon, J. R., and Galli, S. J. (1990) Nature 346, 274-276
3. Malaviya, R., Malaviya, R., and Jakschik, B. A. (1993) J. Biol. Chem. 268, 4939-4944
4. Hamawy, M. J., Mergenhagen, S. E., and Siraganian, R. P. (1995) Cell. Signalling 7, 535-544
5. Blank, U., Ra, C., Miller, L., White, K., Metzger, H., and Kinet, J. P. (1989) Nature 337, 187-189
6. Scharenberg, A. M., Lin, S. Cuenod, B., Yamamura, H., and Kinet, J. P. (1995) EMBO J. 14, 3385-3395
7. Costello, P. S., Turner, M., Walters, A. E., Cunningham, C. N., Bauer, P. H., Downward, J., and Tybulewicz, V. L. (1996) Oncogene 13, 2595-2605
8. Miyazaki, T., and Taniguchi, T. (1996) Cancer Surveys 27, 25-39
9. Levy, D. E. (1997) Cytokine Growth Factor Rev. 8, 81-90
10. Ihle, J. N., and Kerr, I. R. (1995) Trends Genet. 11, 69-74
11. Darnell, J. E., Jr., Kerr, I. M., and Stark, G. R. (1994) Science 264, 1415-1421
12. Nosaka, T., van Deursen, J. M., Tripp, R. A., Thierfelder, W. E., Witthuhn, B. A., McMickle, A. P., Doherty, P. C., Grosveld, G. C., and Ihle J. N. (1995) Science 270, 800-802
13. Thomis, D. C., Gurniak, C. B., Tivol, E., Sharpe, A. H., and Berg, L. J. (1995) Science 270, 794-797
14. Villa, A., Sironi, M., Macchi, P., Matteucci, C., Notarangelo, L. D., Vezzoni, P., and Mantovani, A. (1996) Blood 88, 817-823
15. Buckley, R. H, Schiff, R. I., Schiff, S. E., Markert, M. L., Williams, L. W., Harville, T. O., Roberts, J. L., and Puck J. M. (1997) J. Pediatr. 130, 378-387
16. Ihle, J. N. (1996) Philos. Trans. R. Soc. Lond-Biol. Sci. 351, 159-166
17. Malaviya, R., and Uckun, F. M. (1999) Biochem. Biophys. Res. Commun. 257, 807-813
18. Goodman, P. A., Niehoff, L. B., and Uckun, F. M. (1998) J. Biol. Chem. 273, 17742-17748
19. Sudbeck, E. A., Liu, X.-P., Narla, R. K., Mahajan, S., Ghosh, S., Mao, C., and Uckun, F. M. (1999) Clin. Cancer Res. 5, 1569-1582
20. Wei, Y., Heghinian, K., Bell, R. L., and Jakschik, B. A. (1986) J. Immunol. 137, 1993-2000
21. Liu, F. T., Bohn, J. W., Ferry, E. L., Yamamoto, H., Molinaro, C. A., Sherman, L. A., Klinman, N. R., and Katz, D. H. (1980) J. Immunol. 124, 2728-2737
22. Riske, F., Hakim, J., Mallamaci, M, Griffin, M., Pilson, B., Tobkes, N., Lin, P., Danho, W., Kochan, J., and Chizzonite R (1991) J. Biol. Chem. 266, 11245-11251
23. Uckun, F. M., Jaszcz, W., Ambrus, J. L., Fauci, A. S., Gajl-peczalska, K. L., Song, C. W., Wick, M. R., Myers, D. E., Waddick, K., and Ledbetter, L. A. (1988) Blood, 71, 13-29
24. Xia, H.-Z., Du, Z., Craig, S., Klisch, G., Noben-Trauth, N., Kochan, J. P., Huff, T. H., Irani, A.-M., and Schwartz, L. B. (1997) J. Immunol. 159, 2911-2921
25. Irani, A.-M., Bradford, T. R., Kepley, C. L., Schechter, N. M., and Schwartz, L. B. (1989) J. Histochem. Cytochem. 37, 1509-1515
26. Uckun, F. M., Narla, R. K., Jun, X., Zeren, T., Venkatachalam, T., Waddick, K. G., Rostostev, A., and Myers, D. E. (1998) Clin. Cancer Res. 4, 901-912
27. Witthuhn, B. A., Williams, M. D., and Uckun, F. M. (1999) Lymphoma Leukemian 32, 289-297
28. Narla, R. K., Liu, X. P., Myers, D. E., and Uckun, F. M. (1998) Clin. Cancer Res. 4, 1405-1414
29. Malaviya, R., Morrison, A. R., and Pentland, A. P. (1996) Histamine in human epidermal cells is induced by ultraviolet light injury. J. Invest. Dermatol. 106, 785-789
30. Malaviya, R., and Abraham S. N. (1995) Methods Enzymol. 253, 27-43
31. Malaviya, R., Ikeda, T., Ross, E. A., and Abraham S. N. (1996) Nature 381, 77-80
32. Ozawa, K., Szallasi, Z., Kazanietz, M. G., Blumberg, P. M., Mischak, H., Mushinski, J. F., and Beaven, M. A. (1993) J. Biol. Chem. 268, 1749-1756
33. Dibirdik, I., Kristupaitis, D., Kurosaki, T., Tuel-Ahlgren, L., Chu, A., Pond, D., Tuong, D, Luben, R., and Uckun, F. M. (1998) J. Biol. Chem. 273, 4035-4039
34. Uckun F. M., Dibirdik, I., Smith, R., Tuel-Ahlgren, L., Chandan-Langlie, M., Schieven, G. L., Waddick, K., Hanson, M., and Ledbetter, J. A. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 3589-3593
35. Zhu, D.-M., Narla, R. K., Fang, W.-H., Chia, N.-C., and Uckun, F. M. (1998) Clin. Cancer Res. 4, 2967-2976
36. Uckun, F. M., Waddick, K. G., Mahajan, S., Jun, X., Takata, M., Bolen, J., and Kurosaki, T. (1996) Science 273, 1096-1100
37. Uckun, F. M., Evans, W. E., Forsyth, C. J., Waddick, K. G., Ahlgren, L. T., Chelstrom, L. M., Burkhardt, A., Bolen, J., and Myers, D. E. (1995) Science 267, 886-891
38. Mahajan, S., Ghosh, S., Sudbeck, E. A., Zheng, Y., Downs, S., Hupke, M., and Uckun, F. M. (1999) J. Biol. Chem. 274, 9587-9599
39. Miyajima, I., Dombrowicz, D., Martin, T. R., Ravetch, J. V., Kinet, J. P., and Galli, S. J. (1997) J. Clin. Invest. 99, 901-914
40. Malaviya, R., Ross, E. A., Jakschik, B. A., and Abraham, S. N., (1994) J. Clin. Invest. 93, 1645-1653
41. Hirasawa, N., Scharenberg, A., Yamamura, H., Beaven, M. A., and Kinet, J.-P. (1995) J. Biol. Chem. 270, 10960-10967
42. Zhang, J., Berenstein, E. H., Evans, R. L., and Siraganian, R. P. (1996) J. Exp. Med. 184, 71-79
43. Siraganian R. P. (1998) in Allergy, Principles and Practice (Middleton, E., Reed, C. E., Ellis, E. F., Adkinson, N. F., Yunginger, J. W., and Busse, W. W., eds) Vol. 1, pp. 204-227, Mosby-Year Book, Inc., St. Louis, MO
44. Oliver, J. M., Burg, D. L., Wilson, B. S., McLaughlin, J. L., and Geahlen, R. L. (1994) J. Biol. Chem. 269, 29697-29703
45. Millard, P. J., Ryan, T. A., Webb, W. W., and Fewtrell, C. (1989) J. Biol. Chem. 264, 19730-19739
46. Wong, A., Cook, M. N., Hwang, S. M., Sarau, H. M., Foley, J. F., and Crooke, S. T. (1992) Biochemistry 31, 4046-4053
47. Apgar, J. R. (1997) J. Cell Sci. 110, 771-780
48. Ghosh, S., Zheng, Y., Jun, X., Narla, R., Mahajan, S., Navara, C., Mao, C., Sudbeck, E. A., and Uckun, F. M. (1999) Clin. Cancer Res. 47, 121-130
49. Hogan, A. D., and Schwartz, L. B. (1997) Methods 13, 43-52
50. Oettgen, H. C., Martin, T. R., Wynshaw-Boris, A., Deng, C., Drazen, J. M., and Leder, P. (1994) Nature 370, 367-370
51. Amir, S, and English, A. M. (1991) Eur. J. Pharmacol. 203, 125-127
52. Nelson, B. H., Lord, J. D., and Greenberg, P. D. (1996) Mol. Cell. Biol. 16, 369-375
53. Endo, T. A., Masuhara, M., Yokouchi, M., Suzuki, R., Sakamoto, H., Mitsui, K., Matsumoto, A., Tanimura, S., Ohtsubo, M., Misawa, H., Miyazaki, T., Leonor, N., Taniguchi, T., Fujita, T., Kanakura, Y., Komiya, S., and Yoshimura, A. (1997) Nature 387, 921-924