Induction of neutrophil chemotactic factor production by staurosporine in rat peritoneal neutrophils

British Journal of Pharmacology

Volumn 121, Issue 8, 1997, Pages 1651-1658

  Edamatsu, Takeo ^a   Xiao, Yi Qun ^a   Tanabe, Jun Ichi ^a   Mue, Suetsugu ^b   Ohuchi, Kazuo ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b Japan   (Japan)

Author keywords

CINC 3; MIP 2; Neutrophil chemotactic factor; Protein kinase C; Staurosporine; Tyrosine kinase

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; CALPHOSTIN C; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; GENISTEIN; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C INHIBITOR; RO 318425; STAUROSPORINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DOSE TIME EFFECT RELATION; IMMUNOASSAY; ISOELECTRIC FOCUSING; MALE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PERITONEUM CELL; PH; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; CHEMOKINES, CXC; CHEMOTACTIC FACTORS; DOSE-RESPONSE RELATIONSHIP, DRUG; GROWTH SUBSTANCES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; NEUTROPHILS; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; STAUROSPORINE; TETRADECANOYLPHORBOL ACETATE;

EID: 0030878670     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701322     Document Type: Article

References (35)

1. ALONSO, A., BAYON, Y. & CRESPO, M.S. (1996). The expression of cytokine-induced neutrophil chemoattractants (CINC-1 and CINC-2) in rat peritoneal macrophages is triggered by Fcγ receptor activation: study of the signaling mechanism. Eur. J. Immunol., 26, 2165-2171.
2. DULGOSZ, A.A. & YUSPA, S.H. (1991). Staurosporine induces protein kinase C agonist effects and maturation of normal and neoplastic mouse keratinocytes in vitro. Cancer Res., 51, 4677-4684.
3. FENG, L., XIA, Y., YOSHIMURA, T. & WILSON, C.B. (1995). Modulation of neutrophil influx in glomerulonephritis in the rat with anti-macrophage inflammatory protein-2 (MIP-2) antibody. J. Clin. Invest., 95, 1009-1017.
4. 3H]dimethylstaurosporine binding to protein kinase C. Biochem. Pharmacol., 40, 343-350.
5. HIDAKA, H., WATANABE, M. & KOBAYASHI, R. (1991). Properties and use of H-series compounds as protein kinase inhibitors. Methods Enzymol., 201, 328-339.
6. ISHIKAWA, Y., MUKAIDA, N., KUNO, K., RICE, N., OKAMOTO, S. & MATSUSHIMA, K. (1995). Establishment of lipopolysaccharide-dependent nuclear factor κB activation in a cell-free system. J. Biol. Chem., 270, 4158-4161.
7. JORDAN, N.J., WATSON, M.L., YOSHIMURA, T. & WESTWICK, J. (1996). Differential effects of protein kinase C inhibitors on chemokine production in human synovial fibroblasts. Br. J. Pharmacol., 117, 1245-1253.
8. KOBAYASHI, E., NAKANO, H., MORIMOTO, M. & TAMAOKI, T. (1989). Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C. Biochem. Biophys. Res. Commun., 159, 548-553.
9. KOCH, A.E., KUNKEL, S.L., BURROWS, J.C., EVANOFF, H.L., HAINES, G.K., POPE, R.M. & STRIETER, R.M. (1991). Synovial tissue macrophage as a source of the chemotactic cytokine IL-8. J. Immunol. 147, 2187-2195.
10. KOCH, A.E., KUNKEL, S.L., HARLOW, L.A., MAZARAKIS, D.D., HAINES, G.K., BURDICK, M.D., POPE, R.M., WALZ, A. & STRIETER, R.M. (1994). Epithelial neutrophil activating peptide-78: a novel chemotactic cytokine for neutrophils in arthritis. J. Clin. Invest., 94, 1012-1018.
11. KOCH, A.E., KUNKEL, S.L., SHAH, M.R., HOSAKA, S., HALLORAN, M.M., HAINES, G.K., BURDICK, M.D., POPE, R.M. & STRIETER, R.M. (1995). Growth-related gene product α: A chemotactic cytokine for neutrophils in rheumatoid arthritis. J. Immunol., 155, 3660-3666.
12. KUNSCH, C. & ROSEN, C.A. (1993). NF-κB subunit-specific regulation of the interleukin-8 promoter. Mol. Cell. Biol., 13, 6137-6146.
13. MATSUSHIMA, K., MORISHITA, K., YOSHIMURA, T., LAVU, S., KOBAYASHI, Y., LEW, W., APPELLA, E., KUNG, H.F., LEONARD, E.J. & OPPENHEIM, J.J. (1988). Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor. J. Exp. Med., 167, 1883-1893.
14. MUKAIDA, N., SHIROO, M. & MATSUSHIMA, K. (1989). Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8. J. Immunol., 143, 1366-1371.
15. NAKADATE, T., JENG, A.Y. & BLUMBERG, P.M. (1988). Comparison of protein kinase C functional assays to clarify mechanisms of inhibitor action. Biochem. Pharmacol., 37, 1541-1545.
16. NAKAGAWA, H., KOMORITA, N., SHIBATA, F., KONISHI, K., FUJIOKA, M. & KATOH, H. (1994). Identification of cytokine-induced neutrophil chemoattractants (CINC), rat GRO/CINC-2α and CINC-2β, produced by granulation tissue in culture: purification, complete amino acid sequences and characterization. Biochem. J., 301, 545-550.
17. NISHIZUKA, Y. (1992). Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science, 258, 607-614.
18. O'BRIAN, C. A. & WARD, N.E. (1990). Staurosporine: a prototype of a novel class of inhibitors or tumor cell invasion? J. Natl. Cancer Inst., 82, 1734-1735.
19. OHMORI, Y., FUKUMOTO, S. & HAMILTON, T.A. (1995). Two structurally distinct κB sequence motifs cooperatively control LPS-induced KC gene transcription in mouse macrophages. J. Immunol., 155, 3593-3600.
20. ROBBINS, M. & McKINNEY, M. (1992). Transcriptional regulation of neuromodulin (GAP-43) in mouse neuroblastoma clone NIE-115 as evaluated by the RT/PCR method. Mol. Brain Res., 13, 83-92.
21. SAKO, T., TAUBER, A.I., JEMG, A.Y., YUSPA, S.H. & BLUMBERG, P.M. (1988). Contrasting actions of staurosporine, a protein kinase C inhibitor, on human neutrophils and primary mouse epidermal cells. Cancer Res., 48, 4646-4650.
22. SHIBATA, F., KONISHI, K., KATOH, H., KOMORITA, N., ALMOKDAD, M., FUJIOKA, M. & NAKAGAWA, H. (1995). Recombinant production and biological properties of rat cytokine-induced neutrophil chemoattractants, GRO/CINC-2α, CINC-2β and CINC-3. Eur. J. Pharmacol., 231, 306-311.
23. ++ dependent protein kinase. Biochem. Biophys. Res. Commun., 135, 397-402.
24. TANABE, J., WATANABE, M., KONDOH, S., MUE, S. & OHUCHI, K. (1994). Possible roles of protein kinases in neutrophil chemotactic factor production by leucocytes in allergic inflammation in rats. Br. J. Pharmacol., 113, 1480-1486.
25. TANABE, J., WATANABE, M., FUJIMOTO, N., MUE, S. & OHUCHI, K. (1995). Characterization of leukocyte-derived neutrophil chemotactic factor-2 and its possible roles in neutrophil infiltration in allergic inflammation in rats. Int. Arch. Allergy Immunol., 108, 148-157.
26. TAYLOR, D.J., EVANSON, J.M. & WOOLLEY, D.E. (1990). Contrasting effects of the protein kinase C inhibitor, staurosporine, on cytokine and phorbol ester stimulation of fructose 2,6-bisphosphate and prostaglandin E production by fibroblasts in vitro. Biochem. J., 269, 573-577.
27. TEKAMP-OLSON, P., GALLEGOS, C., BAUER, D., MCCLAIN, J., SHERRY, B., FABRE, M., VAN-DEVENTER, S. & CERAMI, A. (1990). Cloning and characterization of cDNAs for murine macrophage inflammatory protein 2 and its human homologues. J. Exp. Med., 172, 911-919.
28. TREMBLAY, L., GINGRAS, D., BOIVIN D. & BE'LIVEAU, R. (1992). Tyrosine protein kianse activity in renal brushborder membrane. Biochim. Biophys. Acta, 1108, 183-189.
29. WATANABE, K., KONISHI, K., FUJIOKA, M., KINOSHITA, S. & NAKAGAWA, H. (1989). The neutrophil chemoattractant produced by the rat kidney epithelioid cell line NRK-52E is a protein related to the KC/gro protein. J. Biol. Chem., 264, 19559-19563.
30. WATANABE, M., TAMURA, T., OHASHI, M., HIRASAWA, N., OZEKI, T., TSURUFUJI, S., FUJIKI, H. & OHUCHI, K. (1990). Dual effects of staurosporine on arachidonic acid metabolism in rat peritoneal macrophages. Biochim. Biophys. Acta, 1047, 141-147.
31. WIDMER, U., MANOGUE, K.R., CERAMI, A. & SHERRY, B. (1993). Genomic cloning and promoter analysis of macrophage inflammatory protein (MIP)-2, MIP-1α, and MIP-1β, members of the chemokine superfamily of proinflammatory cytokines. J. Immunol., 150, 4996-5012.
32. WILKINSON, S.E. & HALLAM, T.J. (1994). Protein kinase C: is its pivotal role in cellular activation over-stated? Trends Pharmacol. Sci., 15, 53-57.
33. WILKINSON, S.E., PARKER, P.J. & NIXON, J.S. (1993). Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C. Biochem. J., 294, 335-337.
34. WOLF, M. & BAGGIOLINI, M. (1988). The protein kinase inhibitor staurosporine, like phorbol esters, induces the association of protein kinase C with membranes. Biochem. Biophys. Res. Commun., 154, 1273-1279.
35. WU, X., WITTWER, A.J., CARR, L.S., CRIPPES, B.A., DELARCO, J.E. & LEFKOWITH, J.B. (1994). Cytokine-induced neutrophil chemoattractant mediates neutrophil influx in immune complex glomerulonephritis in rat. J. Clin. Invest., 94, 337-344.