Development of selective ligands for benzodiazepine receptor subtypes by manipulating the substituents at positions 3- and 7- of optically active BzR ligands

Medicinal Chemistry Research

Volumn 13, Issue 5, 2004, Pages 259-281

  Li, Xiaoyan ^a   Yu, Jianming ^a   Atack, John R ^b   Cook, James M ^a  

^a UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^b NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

11,12,13,13A TETRAHYDRO 7 ACETYLENYL 9 OXO 9H IMIDAZO[1,5 A]PYRROLO[2,1 C][1,4]BENZODIAZEPINE 1 CARBOXYLATE; 2 (4 CHLOROPHENYL) 5H PYRAZOLO[4,3 C]QUINOLIN 3 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; 7 ACETYLENOPYRROLOIMIDAZOBENZODIAZEPINE; BENZODIAZEPINE DERIVATIVE; BENZODIAZEPINE RECEPTOR; DIAZEPAM; DIINDOLE DERIVATIVE; IMIDAZOBENZODIAZEPINE; INDOLE DERIVATIVE; LIGAND; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

AGONIST; ARTICLE; BINDING ASSAY; BINDING SITE; CONFORMATIONAL TRANSITION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; ISOMER; LIPOPHILICITY; PHARMACOPHORE; RECEPTOR AFFINITY; STEREOCHEMISTRY; STRUCTURE ANALYSIS; SYNTHESIS;

EID: 22944480590     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-004-0033-7     Document Type: Article

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