Structure of the subtilisin Carlsberg-OMTKY3 complex reveals two different ovomucoid conformations

Acta Crystallographica Section D: Biological Crystallography

Volumn 61, Issue 5, 2005, Pages 580-588

  Maynes, Jason T ^a   Cherney, Maia M ^a   Qasim, M A ^b   Laskowski Jr , Michael ^b   James, Michael N G ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHYMOTRYPSIN; CHYMOTRYPSIN A; ENZYME INHIBITOR; LEUKOCYTE ELASTASE; OVOMUCOID; SUBTILISIN;

ANIMAL; ARTICLE; CATTLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; HUMAN; PROTEIN BINDING; PROTEIN CONFORMATION; STATISTICAL ANALYSIS; STRUCTURE ACTIVITY RELATION; TURKEY (BIRD); X RAY CRYSTALLOGRAPHY;

ANIMALS; CATTLE; CHYMOTRYPSIN; CRYSTALLOGRAPHY, X-RAY; DATA INTERPRETATION, STATISTICAL; ENZYME INHIBITORS; HUMANS; LEUKOCYTE ELASTASE; MODELS, MOLECULAR; OVOMUCIN; PROTEIN BINDING; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; SUBTILISINS; TURKEYS;

EID: 22844438533     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444905004889     Document Type: Article

References (32)

1. Apostol, I., Giletto, A., Komiyama, T., Zhang, W. & Laskowski, M. Jr (1993). J. Protein Chem. 12, 419-433.
2. Ardelt, W. & Laskowski, M. Jr (1985). Biochemistry. 24, 5313-5320.
3. Barrett, A. J., Rawlings, N. D. & Woessner, J. F. (1998). Handbook of Proteolytic Enzymes. London: Academic Press.
4. Bateman, K. S., Anderson, S., Lu, W., Qasim, M. A., Laskowski, M. Jr & James, M. N. G. (2000). Protein Sci. 9, 83-94.
5. Bateman, K. S., Huang, K., Anderson, S., Lu, W., Qasim, M. A., Laskowski, M. Jr & James, M. N. G. (2001). J. Mol. Biol. 305, 839-849.
6. Bode, W. & Huber, R. (1992). Eur. J. Biochem. 204, 433-451.
7. Bode, W., Papamokos, E. & Musil, D. (1987). Eur. J. Biochem. 166, 673-692.
8. Bode, W., Wei, A. Z., Huber, R., Meyer, E., Travis, J. & Neumann, S. (1986). EMBO J. 5, 2453-2458.
9. Collaborative Computational Project, Number 4 (1994). Acta Cryst. D50, 760-763.
10. DeLano, W. L. (2002). The PyMOL Users Manual. San Carlos, CA, USA: DeLano Scientific.
11. Delbaere, L. T., Hutcheon, W. L., James, M. N. G. & Thiessen, W. E. (1975). Nature (London), 257, 758-763.
12. Fujinaga, M., Read, R. J., Sielecki, A., Ardelt,W., Laskowski, M. Jr & James, M. N. (1982). Proc. Natl Acad. Sci. USA, 79, 4868-4872.
13. Fujinaga, M., Sielecki, A. R., Read, R. J., Ardelt,W., Laskowski,M. Jr & James, M. N. G. (1987). J. Mol. Biol. 195, 397-418.
14. Hooft, R. W., Vriend, G., Sander, C. & Abola, E. E. (1996). Nature (London), 381, 272.
15. Horn, J. R., Ramaswamy, S. & Murphy, K. P. (2003). J. Mol. Biol. 331, 497-508.
16. Huang, K., Lu, W. Y., Anderson, S., Laskowski, M. & James, M. N. G. (1995). Protein Sci. 4, 1985-1997.
17. Laskowski, M. Jr & Kato, I. (1980). Annu. Rev. Biochem. 49, 593-626.
18. Laskowski, M. & Qasim, M. A. (2000). Biochim Biophys Acta, 1477, 324-337.
19. Laskowski, M. Jr, Qasim, M. A. & Lu, S. M. (2000). Protein-Protein Recognition, ch. 8, edited by C. Kleanthous. Oxford University Press.
20. Laskowski, R. A., Moss, D. S. & Thornton, J. M. (1993). J. Mol. Biol. 231, 1049-1067.
21. Lu, S. M. et al. (2001). Proc. Natl Acad. Sci. USA, 98, 1410-1415.
22. McGaughey, G. B., Gagne, M. & Rappe, A. K. (1998). J. Biol. Chem. 273, 15458-15463.
23. McRee, D. E. (1999). J. Struct. Biol. 125, 156-165.
24. Murshudov, G. N., Vagin, A. A. & Dodson, E. J. (1997). Acta Cryst. D53, 240-255.
25. Navaza, J. & Saludjian, P. (1997). Methods Enzymol. 276, 581-593.
26. Perrakis, A., Morris, R. & Lamzin, V. S. (1999). Nature Struct. Biol. 6, 458-463.
27. Powell, H. R. (1999). Acta Cryst. D55, 1690-1695.
28. Radisky, E. S. & Koshland, D. E. (2002). Proc. Natl Acad. Sci. USA, 99, 10316-10321.
29. Read, R. J., Fujinaga, M., Sielecki, A. R. & James, M. N. (1983). Biochemistry, 22, 4420-4433.
30. Read, R. J. & James, M. N. G. (1986). In Proteinase Inhibitors, edited by A. J. Barrett & G. Salvesen. Amsterdam: Elsevier.
31. Schechter, I. & Berger, A. (1967). Biochem. Biophys. Res. Commun. 27, 157-162.
32. Yang, S. Q., Wang, C. I., Gillmor, S. A., Fletterick, R. J. & Craik, C. S. (1998). J. Mol. Biol. 279, 945-957.