Proteasome inhibition induces TNFR1 shedding from human airway epithelial (NCI-H292) cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 289, Issue 2 33-2, 2005, Pages

  Levine, Stewart J ^a   Adamik, Barbara ^a   Hawari, Feras I ^a   Islam, Aminul ^a   Yu, Zu Xi ^a   Liao, Da Wei ^a   Zhang, Jing ^a   Cui, Xinle ^a   Rouhani, Farshid N ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Soluble tumor necrosis factor receptors; Vesicular trafficking

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR; LACTACYSTIN BETA LACTONE; PROTEASOME; PROTEASOME INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; UBIQUITIN;

ARTICLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LUNG ALVEOLUS EPITHELIUM; PNEUMONIA; PRIORITY JOURNAL;

ADENOCARCINOMA; APOPTOSIS; CARCINOMA, MUCOEPIDERMOID; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; HUMANS; HYDROXAMIC ACIDS; LACTONES; METALLOPROTEASES; PROTEASOME ENDOPEPTIDASE COMPLEX; RECEPTORS, CELL SURFACE; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RESPIRATORY MUCOSA; RESPIRATORY SYSTEM; UMBILICAL VEINS;

EID: 22444449301     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00469.2004     Document Type: Article

References (46)

1. Adams J. The development of proteasome inhibitors as anticancer drugs. Cancer Cell 5: 417-421, 2004.
2. Amrani Y, Ammit AJ, and Panettieri RA Jr. Tumor necrosis factor receptor (TNFR) 1, but not TNFR2, mediates tumor necrosis factor-α-induced interleukin-6 and RANTES in human airway smooth muscle cells: role of p38 and p42/44 mitogen-activated protein kinases. Mol Pharmacol 60: 646-655, 2001.
3. Aupeix K, Hugel B, Martin T, Bischoff P, Lill H, Pasquali JL, and Freyssinet JM. The significance of shed membrane particles during programmed cell death in vitro, and in vivo, in HIV-1 infection. J Clin Invest 99: 1546-1554, 1997.
4. Balkwill F, Foxwell B, and Brennan F. TNF is here to stay! Immunol Today 21: 470-471, 2000.
5. Ben-Neriah Y. Regulatory functions of ubiquitination in the immune system. Nat Immun 3: 20-26, 2002.
6. Bradley JR, Thiru S, and Pober JS. Disparate localization of 55-kd and 75-kd tumor necrosis factor receptors in human endothelial cells. Am J Pathol 146: 27-32, 1995.
7. Brakebusch C, Varfolomeev EE, Batkin M, and Wallach D. Structural requirements for inducible shedding of the p55 tumor necrosis factor receptor. J Biol Chem 269: 32488-32496, 1994.
8. Chen G and Goeddel DV. TNF-R1 signaling: a beautiful pathway. Science 296: 1634-1635, 2002.
9. Cui X, Hawari F, Alsaaty S, Lawrence M, Combs CA, Geng W, Rouhani FN, Miskinis D, and Levine SJ. Identification of ARTS-1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding. J Clin Invest 110: 515-526, 2002.
10. Delic J, Masdehors P, Omura S, Cosset JM, Dumont J, Binet JL, and Magdelenat H. The proteasome inhibitor lactacystin induces apoptosis and sensitizes chemo- and radioresistant human chronic lymphocytic leukaemia lymphocytes to TNF-α-initiated apoptosis. Br J Cancer 77: 1103-1107, 1998.
11. Denzer K, Kleijmeer MJ, Heijnen HF, Stoorvogel W, and Geuze HJ. Exosome: from internal vesicle of the multivesicular body to intercellular signaling device. J Cell Sci 113: 3365-3374, 2000.
12. Engelmann H, Aderka D, Rubinstein M, Rotman D, and Wallach D. A tumor necrosis factor-binding protein purified to homogeneity from human urine protects cells from tumor necrosis factor toxicity. J Biol Chem 264: 11974-11980, 1989.
13. Engelmann H, Novick D, and Wallach D. Two tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors. J Biol Chem 265: 1531-1536, 1990.
14. Fenteany G and Schreiber SL. Lactacystin, proteasome function, and cell fate. J Biol Chem 273: 8545-8548, 1998.
15. Gomez MI, Lee A, Reddy B, Muir A, Soong G, Pitt A, Cheung A, and Prince A. Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1. Nat Med 10: 842-848, 2004.
16. Gould SJ, Booth AM, and Hildreth JE. The Trojan exosome hypothesis. Proc Natl Acad Sci USA 100: 10592-10597, 2003.
17. Hawari FI, Rouhani FN, Cui X, Yu ZX, Buckley C, Kaler M, and Levine SJ. Release of full-length 55-kDa TNF receptor 1 in exosome-like vesicles: a mechanism for generation of soluble cytokine receptors. Proc Natl Acad Sci USA 101: 1297-1302, 2004.
18. Heijnen HF, Schiel AE, Fijnheer R, Geuze HJ, and Sixma JJ. Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and α-granules. Blood 94: 3791-3799, 1999.
19. Imajoh-Ohmi S, Kawaguchi T, Sugiyama S, Tanaka K, Omura S, and Kikuchi H. Lactacystin, a specific inhibitor of the proteasome, induces apoptosis in human monoblast U937 cells. Biochem Biophys Res Commun 217: 1070-1077, 1995.
20. Jones SJ, Ledgerwood EC, Prins JB, Galbraith J, Johnson DR, Pober JS, and Bradley JR. TNF recruits TRADD to the plasma membrane but not the trans-Golgi network, the principal subcellular location of TNF-R1. J Immunol 162: 1042-1048, 1999.
21. Kanaly ST, Nashleanas M, Hondowicz B, and Scott P. TNF receptor p55 is required for elimination of inflammatory cells following control of intracellular pathogens. J Immunol 163: 3883-3889, 1999.
22. Kitagawa H, Tani E, Ikemoto H, Ozaki I, Nakano A, and Omura S. Proteasome inhibitors induce mitochondria-independent apoptosis in. human glioma cells. FEBS Lett 443: 181-186, 1999.
23. Lee DH and Goldberg AL. Selective inhibitors of the proteasome-dependent and vacuolar pathways of protein degradation in Saccharomyces cerevisiae. J Biol Chem 271: 27280-27284, 1996.
24. Legler DF, Micheau O, Doucey MA, Tschopp J, and Bron C. Recruitment of TNF receptor 1 to lipid rafts is essential for TNFα-mediated NF-κB activation. Immunity 18: 655-664, 2003.
25. Levine SJ, Logun C, Chopra DP, Rhim JS, and Shelhamer JH. Protein kinase C, interleukin-1β, and corticosteroids regulate shedding of the type I, 55 kDa TNF receptor from human airway epithelial cells. Am J Respir Cell Mol Biol 14: 254-261, 1996.
26. Madge LA, Sierra-Honigmann MR, and Pober JS. Apoptosis-inducing agents cause rapid shedding of tumor necrosis factor receptor 1 (TNFR1). A nonpharmacological explanation for inhibition of TNF-mediated activation. J Biol Chem 274: 13643-13649, 1999.
27. Marques C, Pereira P, Taylor A, Liang JN, Reddy VN, Szweda LI, and Shang F. Ubiquitin-dependent lysosomal degradation of the HNE-modified proteins in lens epithelial cells. FASEB J 18: 1424-1426, 2004.
28. Melman L, Geuze HJ, Li Y, McCormick LM, Van Kerkhof P, Strous GJ, Schwartz AL, and Bu G. Proteasome regulates the delivery of LDL receptor-related protein into the degradation pathway. Mol Biol Cell 13: 3325-3335, 2002.
29. Nophar Y, Kemper O, Brakebusch C, Engelmann H, Zwang R, Aderka D, Holtmann H, and Wallach D. Soluble forms of the tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor. EMBO J 9: 3269-3278, 1990.
30. Okada K, Wangpoengtrakul C, Osawa T, Toyokuni S, Tanaka K, and Uchida K. 4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules. J Biol Chem 274: 23787-23793, 1999.
31. Olsson I, Lantz M, Nilsson E, Peetre C, Thysell H, Grubb A, and Adolf G. Isolation and characterization of a tumor necrosis factor binding protein from urine. Eur J Haematol 42: 270-275, 1989.
32. Omura S, Fujimoto T, Otoguro K, Matsuzaki K, Moriguchi R, Tanaka H, and Sasaki Y. Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells. J Antibiot (Tokyo) 44: 113-116, 1991.
33. Pantano C, Shrivastava P, McElhinney B, and Janssen-Heininger Y. Hydrogen peroxide signaling through tumor necrosis factor receptor 1 leads to selective activation of c-Jun N-terminal kinase. J Biol Chem 278: 44091-44096, 2003.
34. Parsons PE, Matthay MA, Ware LB, and Eisner MD. Elevated plasma levels of soluble TNF receptors are associated with morbidity and mortality in patients with acute lung injury. Am J Physiol Lung Cell Mol Physiol 288: L426-L431, 2005.
35. Raposo G, Nijman HW, Stoorvogel W, Leijendekker R, Harding CV, Melief CJM, and Geuze HJ. B lymphocytes secrete antigen-presenting vesicles. J Exp Med 183: 1161-1172, 1998.
36. Reddy P, Slack JL, Davis R, Cerretti DP, Kozlosky CJ, Blanton RA, Shows D, Peschon JJ, and Black RA. Functional analysis of the domain structure of tumor necrosis factor-α converting enzyme. J Biol Chem 275: 14608-14614, 2000.
37. Schall TJ, Lewis M, Koller KJ, Lee A, Rice GC, Wong GHW, Gatanaga T, Granger GA, Lentz R, Raab H, Kohr WJ, and Goeddel DV. Molecular cloning and expression of a receptor for human tumor necrosis factor. Cell 61: 361-370, 1990.
38. Seckinger P, Isaaz S, and Dayer JM. Purification and biologic characterization of a specific tumor necrosis factor alpha inhibitor. J Biol Chem 264: 11966-11973, 1989.
39. Skerrett SJ, Martin TR, Chi EY, Peschon JJ, Mohler KM, and Wilson CB. Role of the type 1 TNF receptor in lung inflammation after inhalation of endotoxin or Pseudomonas aeruginosa. Am J Physiol Lung Cell Mol Physiol 276: L715-L727, 1999.
40. Song Y, Ao L, Raeburn CD, Calkins CM, Abraham E, Harken AH, and Meng X. A low level of TNF-α mediates hemorrhage-induced acute lung injury via p55 TNF receptor. Am J Physiol Lung Cell Mol Physiol 281: L677-L684, 2001.
41. Théry C, Zitvogel L, and Amigorena S. Exosomes: composition, biogenesis and function. Nat Rev Immunol 2: 569-579, 2002.
42. Van Kerkhof P, Covers R, Alves dos Santos CM, and Strous GJ. Endocytosis and degradation of the growth hormone receptor are proteasome-dependent. J Biol Chem 275: 1575-1580, 2000.
43. Wajant H, Pfizenmaier K, and Scheurich P. Tumor necrosis factor signaling. Cell Death Differ 10: 45-65, 2003.
44. Wallach D, Aderka D, Engelmann H, Nophar Y, Kemper O, Holtmann H, Brakebusch C, Villa S, Gondi FG, Bucciarelli U, and Brakebusch C. Cell surface and soluble TNF receptors. In: Tumor Necrosis Factor: Structure-Function Relationship and Clinical Application, edited by Osawa T and Bonavida B. Basel: Karger, 1991, p. 47-57.
45. Wang J, Al-Lamki RS, Zhang H, Kirkiles-Smith N, Gaeta ML, Thiru S, Pober JS, and Bradley JR. Histamine antagonizes tumor necrosis factor (TNF) signaling by stimulating TNF receptor shedding from the cell surface and Golgi storage pool. J Biol Chem 278: 21751-21760, 2003.
46. Yu A and Malek TR. The proteasome regulates receptor-mediated endocytosis of interleukin-2. J Biol Chem 276: 381-385, 2001.