메뉴 건너뛰기




Volumn 26, Issue 6, 2005, Pages 1021-1034

Reduced E-cadherin expression contributes to the loss of p27 kip1-mediated mechanism of contact inhibition in thyroid anaplastic carcinomas

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CYCLIN A; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; UVOMORULIN; CADHERIN; CELL CYCLE PROTEIN; CTNNB1 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE; CYCLINE; CYTOSKELETON PROTEIN; TRANSACTIVATOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

EID: 22344451906     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgi050     Document Type: Article
Times cited : (55)

References (57)
  • 1
    • 0030589575 scopus 로고    scopus 로고
    • Cell contact-dependent signaling
    • Fagotto, F. and Gumbiner, B.M. (1996) Cell contact-dependent signaling. Dev. Biol., 180, 445-454.
    • (1996) Dev. Biol. , vol.180 , pp. 445-454
    • Fagotto, F.1    Gumbiner, B.M.2
  • 2
    • 0018672617 scopus 로고
    • Contact inhibition and malignancy
    • Abercrombie, M. (1979) Contact inhibition and malignancy. Nature, 281, 259-262.
    • (1979) Nature , vol.281 , pp. 259-262
    • Abercrombie, M.1
  • 3
    • 0031983461 scopus 로고    scopus 로고
    • Opposite transcriptional effects of cyclic AMP-responsive elements in confluent or p27KIP-overexpressing cells versus serum-starved or growing cells
    • Deleu, L., Fuks, F., Spitkovsky, D., Horlein, R., Faisst, S. and Rommelaere, J. (1998) Opposite transcriptional effects of cyclic AMP-responsive elements in confluent or p27KIP-overexpressing cells versus serum-starved or growing cells. Mol. Cell. Biol., 18, 409-419.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 409-419
    • Deleu, L.1    Fuks, F.2    Spitkovsky, D.3    Horlein, R.4    Faisst, S.5    Rommelaere, J.6
  • 4
    • 0030668825 scopus 로고    scopus 로고
    • Differences in the mechanisms of growth control in contact-inhibited and serum-deprived human fibroblasts
    • Dietrich, C., Wallenfang, K., Oesch, F. and Wieser, R. (1997) Differences in the mechanisms of growth control in contact-inhibited and serum-deprived human fibroblasts. Oncogene, 15, 2743-2747.
    • (1997) Oncogene , vol.15 , pp. 2743-2747
    • Dietrich, C.1    Wallenfang, K.2    Oesch, F.3    Wieser, R.4
  • 5
    • 0030950796 scopus 로고    scopus 로고
    • Inactivation of the cyclin D-dependent kinase in the rat fibroblast cell line, 3Y1, induced by contact inhibition
    • Kato, A., Takahashi, H., Takahashi, Y. and Matsushime, H. (1997) Inactivation of the cyclin D-dependent kinase in the rat fibroblast cell line, 3Y1, induced by contact inhibition. J. Biol. Chem., 272, 8065-8070.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8065-8070
    • Kato, A.1    Takahashi, H.2    Takahashi, Y.3    Matsushime, H.4
  • 6
    • 0028179669 scopus 로고
    • P27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest
    • Polyak, K., Kato, J.Y., Solomon, M.J., Sherr, C.J., Massague, J., Roberts, J.M. and Koff, A. (1994) p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. Genes Dev., 8, 9-22.
    • (1994) Genes Dev. , vol.8 , pp. 9-22
    • Polyak, K.1    Kato, J.Y.2    Solomon, M.J.3    Sherr, C.J.4    Massague, J.5    Roberts, J.M.6    Koff, A.7
  • 7
    • 0016714582 scopus 로고
    • Control of growth of mammalian cells in cell culture
    • Holley, R.W. (1975) Control of growth of mammalian cells in cell culture. Nature, 258, 487-490.
    • (1975) Nature , vol.258 , pp. 487-490
    • Holley, R.W.1
  • 8
    • 0027380638 scopus 로고
    • Submembranous junctional plaque proteins include potential tumour suppressor molecules
    • Tsukita, S., Itoh, M., Nagafuchi, A., Yonemura, S. and Tsukita, S. (1993) Submembranous junctional plaque proteins include potential tumour suppressor molecules. J. Cell. Biol., 123, 1049-1053.
    • (1993) J. Cell. Biol. , vol.123 , pp. 1049-1053
    • Tsukita, S.1    Itoh, M.2    Nagafuchi, A.3    Yonemura, S.4    Tsukita, S.5
  • 9
    • 0041561057 scopus 로고    scopus 로고
    • Cell adhesion system and human cancer morphogenesis
    • Hirohashi, S. and Kanai, Y. (2003) Cell adhesion system and human cancer morphogenesis. Cancer Sci., 94, 575-581.
    • (2003) Cancer Sci. , vol.94 , pp. 575-581
    • Hirohashi, S.1    Kanai, Y.2
  • 10
    • 0026318366 scopus 로고
    • Neural cell adhesion molecule mediates contact-dependent inhibition of growth of near-diploid mouse fibroblast cell line m5S/1 M
    • Aoki, J., Umeda, M., Takio, K., Titani, K., Utsumi, H., Sasaki, M. and Inoue, K. (1991) Neural cell adhesion molecule mediates contact-dependent inhibition of growth of near-diploid mouse fibroblast cell line m5S/1 M. J. Cell. Biol., 115, 1751-1761.
    • (1991) J. Cell. Biol. , vol.115 , pp. 1751-1761
    • Aoki, J.1    Umeda, M.2    Takio, K.3    Titani, K.4    Utsumi, H.5    Sasaki, M.6    Inoue, K.7
  • 11
    • 0030578460 scopus 로고    scopus 로고
    • Density-dependent inhibition of growth involves prevention of EGF receptor activation by E-cadherin-mediated cell-cell adhesion
    • Takahashi, K. and Suzuki, K. (1996) Density-dependent inhibition of growth involves prevention of EGF receptor activation by E-cadherin-mediated cell-cell adhesion. Exp. Cell Res., 226, 214-222.
    • (1996) Exp. Cell Res. , vol.226 , pp. 214-222
    • Takahashi, K.1    Suzuki, K.2
  • 12
    • 33744907308 scopus 로고    scopus 로고
    • Cadherin-mediated adhesion is required for normal growth regulation of human gingival epithelial cells
    • Kandikonda, S., Oda, D., Niederman, R. and Sorkin, B.C. (1996) Cadherin-mediated adhesion is required for normal growth regulation of human gingival epithelial cells. Cell. Adhes. Commun., 4, 13-24.
    • (1996) Cell. Adhes. Commun. , vol.4 , pp. 13-24
    • Kandikonda, S.1    Oda, D.2    Niederman, R.3    Sorkin, B.C.4
  • 13
    • 0031440104 scopus 로고    scopus 로고
    • Molecular and functional analysis of cadherin-based adherens junctions
    • Yap, A.S., Brieher, W.M. and Gumbiner, B.M. (1997) Molecular and functional analysis of cadherin-based adherens junctions. Annu. Rev. Cell Dev. Biol., 13, 119-146.
    • (1997) Annu. Rev. Cell Dev. Biol. , vol.13 , pp. 119-146
    • Yap, A.S.1    Brieher, W.M.2    Gumbiner, B.M.3
  • 14
    • 0034614941 scopus 로고    scopus 로고
    • Regulation of cadherin adhesive activity
    • Gumbiner, B.M. (2000) Regulation of cadherin adhesive activity. J. Cell. Biol., 148, 399-404.
    • (2000) J. Cell. Biol. , vol.148 , pp. 399-404
    • Gumbiner, B.M.1
  • 15
    • 0033611586 scopus 로고    scopus 로고
    • P27 is involved in N-cadherin-mediated contact inhibition of cell growth and S-phase entry
    • Levenberg, S., Yarden, A., Kam, Z. and Geiger, B. (1999) p27 is involved in N-cadherin-mediated contact inhibition of cell growth and S-phase entry. Oncogene, 18, 869-876.
    • (1999) Oncogene , vol.18 , pp. 869-876
    • Levenberg, S.1    Yarden, A.2    Kam, Z.3    Geiger, B.4
  • 17
    • 0032572526 scopus 로고    scopus 로고
    • E-cadherin-dependent growth suppression is mediated by the cyclin-dependent kinase inhibitor p27(KIP1)
    • St Croix, B., Sheehan, C., Rak, J.W., Florenes, V.A., Slingerland, J.M. and Kerbel, R.S. (1998) E-cadherin-dependent growth suppression is mediated by the cyclin-dependent kinase inhibitor p27(KIP1). J. Cell. Biol., 142, 557-571.
    • (1998) J. Cell. Biol. , vol.142 , pp. 557-571
    • St. Croix, B.1    Sheehan, C.2    Rak, J.W.3    Florenes, V.A.4    Slingerland, J.M.5    Kerbel, R.S.6
  • 18
    • 0038052805 scopus 로고    scopus 로고
    • The cell cycle: A review of regulation, deregulation and therapeutic targets in cancer
    • Vermeulen, K., Van Bockstaele, D.R. and Berneman, Z.N. (2003) The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer. Cell Prolif., 36, 131-149.
    • (2003) Cell Prolif. , vol.36 , pp. 131-149
    • Vermeulen, K.1    Van Bockstaele, D.R.2    Berneman, Z.N.3
  • 23
    • 0033783980 scopus 로고    scopus 로고
    • Anaplastic thyroid carcinoma: Current diagnosis and treatment
    • Giuffrida, D. and Gharib, H. (2000) Anaplastic thyroid carcinoma: current diagnosis and treatment. Ann. Oncol., 11, 1083-1089.
    • (2000) Ann. Oncol. , vol.11 , pp. 1083-1089
    • Giuffrida, D.1    Gharib, H.2
  • 27
    • 0034092911 scopus 로고    scopus 로고
    • Regulation of the cdk inhibitor p27 and its deregulation in cancer
    • Slingerland, J. and Pagano, M. (2000) Regulation of the cdk inhibitor p27 and its deregulation in cancer. J. Cell. Physiol., 183, 10-17.
    • (2000) J. Cell. Physiol. , vol.183 , pp. 10-17
    • Slingerland, J.1    Pagano, M.2
  • 28
    • 0042532260 scopus 로고    scopus 로고
    • kip1 deregulation in cancer: Down-regulation or mislocalization?
    • kip1 deregulation in cancer: down-regulation or mislocalization? Cell Cycle, 1, 394-400.
    • (2002) Cell Cycle , vol.1 , pp. 394-400
    • Viglietto, G.1    Motti, M.L.2    Fusco, A.3
  • 29
    • 0029670477 scopus 로고    scopus 로고
    • Kip1 accumulation during the cell cycle
    • Kip1 accumulation during the cell cycle. Science, 271, 1861-1864.
    • (1996) Science , vol.271 , pp. 1861-1864
    • Hengst, L.1    Reed, S.I.2
  • 31
    • 0028129695 scopus 로고
    • Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line
    • Watabe, M., Nagafuchi, A., Tsukita, S. and Takeichi, M. (1994) Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line. J. Cell. Biol., 127, 247-256.
    • (1994) J. Cell. Biol. , vol.127 , pp. 247-256
    • Watabe, M.1    Nagafuchi, A.2    Tsukita, S.3    Takeichi, M.4
  • 32
    • 0032587780 scopus 로고    scopus 로고
    • Downregulation of p27KIP1 and Ki67/Mib1 labeling index support the classification of thyroid carcinoma into prognostically relevant categories
    • Tallini, G., Garcia-Rostan, G., Herrero, A., Zelterman, D., Viale, G., Bosari, S. and Carcangiu, M.L. (1999) Downregulation of p27KIP1 and Ki67/Mib1 labeling index support the classification of thyroid carcinoma into prognostically relevant categories. Am. J. Surg. Pathol., 23, 678-685.
    • (1999) Am. J. Surg. Pathol. , vol.23 , pp. 678-685
    • Tallini, G.1    Garcia-Rostan, G.2    Herrero, A.3    Zelterman, D.4    Viale, G.5    Bosari, S.6    Carcangiu, M.L.7
  • 34
    • 0028227197 scopus 로고
    • A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells
    • Slingerland, J.M., Hengst, L., Pan, C.H., Alexander, D., Stampfer, M.R. and Reed, S.I. (1994) A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells. Mol. Cell. Biol., 14, 3683-3694.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3683-3694
    • Slingerland, J.M.1    Hengst, L.2    Pan, C.H.3    Alexander, D.4    Stampfer, M.R.5    Reed, S.I.6
  • 37
    • 0030010591 scopus 로고    scopus 로고
    • Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumours
    • Nakayama, K., Ishida, N., Shirane, M., Inomata, A., Inoue, T., Shishido, N., Horii, I., Loh, D.Y. and Nakayama, K. (1996) Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumours. Cell, 87, 707-720.
    • (1996) Cell , vol.87 , pp. 707-720
    • Nakayama, K.1    Ishida, N.2    Shirane, M.3    Inomata, A.4    Inoue, T.5    Shishido, N.6    Horii, I.7    Loh, D.Y.8    Nakayama, K.9
  • 38
    • 0035842536 scopus 로고    scopus 로고
    • Transcriptional up-regulation of p27(Kip1) during contact-induced growth arrest in vascular endothelial cells
    • Hirano, M., Hirano, K., Nishimura, J. and Kanaide, H. (2001) Transcriptional up-regulation of p27(Kip1) during contact-induced growth arrest in vascular endothelial cells. Exp. Cell Res., 271, 356-367.
    • (2001) Exp. Cell Res. , vol.271 , pp. 356-367
    • Hirano, M.1    Hirano, K.2    Nishimura, J.3    Kanaide, H.4
  • 39
    • 0027301125 scopus 로고
    • Decreased E-cadherin immunoreactivity correlates with poor survival in patients with bladder tumors
    • Bringuier, P.P., Umbas, R., Schaafsma, H.E., Karthaus, H.F., Debruyne, F.M. and Schalken, J.A. (1993) Decreased E-cadherin immunoreactivity correlates with poor survival in patients with bladder tumors. Cancer Res., 53, 3241-3245.
    • (1993) Cancer Res. , vol.53 , pp. 3241-3245
    • Bringuier, P.P.1    Umbas, R.2    Schaafsma, H.E.3    Karthaus, H.F.4    Debruyne, F.M.5    Schalken, J.A.6
  • 43
    • 0031830664 scopus 로고    scopus 로고
    • Inactivation of the E-cadherin-mediated cell adhesion system in human cancers
    • Hirohashi, S. (1998) Inactivation of the E-cadherin-mediated cell adhesion system in human cancers. Am. J. Pathol., 153, 333-339.
    • (1998) Am. J. Pathol. , vol.153 , pp. 333-339
    • Hirohashi, S.1
  • 45
    • 0029951738 scopus 로고    scopus 로고
    • E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain
    • Berx, G., Cleton-Jansen, A.M., Strumane, K., de Leeuw, W.J., Nollet, F., van Roy, F. and Cornelisse, C. (1996) E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain. Oncogene, 13, 1919-1925.
    • (1996) Oncogene , vol.13 , pp. 1919-1925
    • Berx, G.1    Cleton-Jansen, A.M.2    Strumane, K.3    De Leeuw, W.J.4    Nollet, F.5    Van Roy, F.6    Cornelisse, C.7
  • 48
    • 0026742310 scopus 로고
    • Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts
    • Matsuyoshi, N., Hamaguchi, M., Taniguchi, S., Nagafuchi, A., Tsukita, S. and Takeichi, M. (1992) Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts. J. Cell. Biol., 118, 703-714.
    • (1992) J. Cell. Biol. , vol.118 , pp. 703-714
    • Matsuyoshi, N.1    Hamaguchi, M.2    Taniguchi, S.3    Nagafuchi, A.4    Tsukita, S.5    Takeichi, M.6
  • 49
    • 0037039315 scopus 로고    scopus 로고
    • Dysadherin, a cancer-associated cell membrane glycoprotein, down-regulates E-cadherin and promotes metastasis
    • Ino, Y., Gotoh, M., Sakamoto, M., Tsukagoshi, K. and Hirohashi, S. (2002) Dysadherin, a cancer-associated cell membrane glycoprotein, down-regulates E-cadherin and promotes metastasis. Proc. Natl Acad. Sci. USA, 99, 365-370.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 365-370
    • Ino, Y.1    Gotoh, M.2    Sakamoto, M.3    Tsukagoshi, K.4    Hirohashi, S.5
  • 51
    • 0025818032 scopus 로고
    • Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
    • Vleminckx, K., Vakaet, L.Jr, Mareel, M., Fiers, W. and van Roy, F. (1991) Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell, 66, 107-119.
    • (1991) Cell , vol.66 , pp. 107-119
    • Vleminckx, K.1    Vakaet Jr., L.2    Mareel, M.3    Fiers, W.4    Van Roy, F.5
  • 53
    • 0031034884 scopus 로고    scopus 로고
    • E-cadherin gene alterations are rare events in thyroid tumors
    • Soares, P., Berx, G., van Roy, F. and Sobrinho-Simoes, M. (1997) E-cadherin gene alterations are rare events in thyroid tumors. Int. J. Cancer, 70, 32-38.
    • (1997) Int. J. Cancer , vol.70 , pp. 32-38
    • Soares, P.1    Berx, G.2    Van Roy, F.3    Sobrinho-Simoes, M.4
  • 54
    • 0032706001 scopus 로고    scopus 로고
    • N-cadherin-mediated adhesion and aberrant catenin expression in anaplastic thyroid-carcinoma cell lines
    • Husmark, J., Heldin, N.E. and Nilsson, M. (1999) N-cadherin-mediated adhesion and aberrant catenin expression in anaplastic thyroid-carcinoma cell lines. Int. J. Cancer, 83, 692-699.
    • (1999) Int. J. Cancer , vol.83 , pp. 692-699
    • Husmark, J.1    Heldin, N.E.2    Nilsson, M.3
  • 55
    • 0035088194 scopus 로고    scopus 로고
    • Clinical significance of E-cadherin expression in thyroid neoplasms
    • Naito, A., Iwase, H., Kuzushima, T., Nakamura, T. and Kobayashi, S. (2001) Clinical significance of E-cadherin expression in thyroid neoplasms. Cancer Res., 76, 176-180.
    • (2001) Cancer Res. , vol.76 , pp. 176-180
    • Naito, A.1    Iwase, H.2    Kuzushima, T.3    Nakamura, T.4    Kobayashi, S.5
  • 56
    • 0030956853 scopus 로고    scopus 로고
    • Immunohistochemical detection of E-cadherin in differentiated thyroid carcinomas correlates with clinical outcome
    • von Wasielewski, R., Rhein, A., Werner, M., Scheumann, G.F., Dralle, H., Potter, E., Brabant, G. and Georgii, A. (1997) Immunohistochemical detection of E-cadherin in differentiated thyroid carcinomas correlates with clinical outcome. Cancer Res., 57, 2501-2507.
    • (1997) Cancer Res. , vol.57 , pp. 2501-2507
    • Von Wasielewski, R.1    Rhein, A.2    Werner, M.3    Scheumann, G.F.4    Dralle, H.5    Potter, E.6    Brabant, G.7    Georgii, A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.