Inhibition of cultured cell growth by vascular endothelial cadherin (cadherin-5/VE-cadherin)

Journal of Clinical Investigation

Volumn 98, Issue 4, 1996, Pages 886-893

  Caveda, L ^a   Martin Padura I ^a   Navarro, P ^a   Breviario, F ^a   Corada, M ^a   Gulino, D ^b   Lampugnani, M G ^a   Dejana, E ^a,b  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b CEA GRENOBLE   (France)

Author keywords

adherence junctions; cadherins; catenins; cell proliferation; endothelium

Indexed keywords

CADHERIN; CATENIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL ADHESION; CELL GROWTH; CHO CELL; CONTROLLED STUDY; ENDOTHELIUM CELL; GROWTH INHIBITION; NONHUMAN; PRIORITY JOURNAL; SIGNAL PROCESSING; VASCULAR ENDOTHELIUM;

EID: 0029816130     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118870     Document Type: Article

References (46)

1. Gimbrone, M.A. 1986. Vascular endothelium: Nature's blood container. In Vascular Endothelium in Hemostasis and Thrombosis. M.A. Gimbrone, Jr., editor. Churchill Livingstone, Edimburgh. UK.1-24.
2. Folkman, J., and Y. Shing. 1992. Angiogenesis. J. Biol. Chem. 267:10931-10934.
3. Ross, R. 1986. The pathogenesis of artherosclerosis - an update. N. Engl. J. Med. 314:488-500.
4. Schwartz, S.M., C.M. Gajdusek, and S.C. Selden. 1981. Vascular wall growth control: the role of the endothelium. Artherosclerosis. 1:107-126.
5. Heimark, R.L., and S.M. Schwartz. 1985. The role of the membrane-membrane interactions in the regulation of endothelial cell growth. J. Cell Biol. 100:1934-1940.
6. Suzuki, S., K. Sano, and H. Tanihara. 1991. Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue. Cell Regulation 2:261-270.
7. 2+-dependent cell-cell adhesion molecule in endothelial cells. J. Cell Biol. 110:1745-1756.
8. Lampugnani, M.G., M. Resnati, M. Raiteri, R. Pigott, A. Pisacane, G. Houen, L.P. Ruco, and E. Dejana. 1992. A novel endothelial specific membrane protein is a marker of cell-cell contacts. J. Cell Biol. 118:1511-1522.
9. Salomon, D., O. Ayalon, R. Patel-King, R.O. Hynes, and B. Geiger. 1992. Extrajunctional distribution of N-cadherin in cultured human endothelial cells. J. Cell Sci. 102:1-11.
10. Dejana, E., M. Corada, and M.G. Lampugnani. 1995. Endothelial cell-to-cell junctions. FASEB J. 9:910-918.
11. Takeichi, M. 1991. Cadherin cell adhesion receptors as a morphogenic regulators. Science (Wash. DC). 251:1451-1455.
12. Geiger, B., and O. Ayalon. 1992. Cadherins. Ann. Rev. Cell Biol. 8:307-332.
13. Kemler, R. 1992. Classical cadherins. Semin. Cell Biol. 3:149-155.
14. Grunwald, G.B. 1993. The structural and functional analysis of cadherin calcium-dependent cell adhesion molecules. Curr. Opin. Cell Biol. 5:797-805.
15. Ranscht, B. 1993. Cadherins and catenins: interactions and functions in embryonic development. Curr. Opin. Cell Biol. 6:740-756.
16. Breviario, F., L. Caveda, M. Corada, I. Martin-Padura, P. Navarro, J. Golay, M. Introna, D. Gulino, M.G. Lampugnani, and E. Dejana. 1995. Functional properties of human VE-cadherin (7B4/cadherin-5) an endothelial specific cadherin. Arterioscler. Thromb. 15:1229-1239.
17. Lampugnani, M.G., M. Corada, L. Caveda, F. Breviario, and E. Dejana. 1995. The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, β-catenin, and α-catenin with vascular endothelial cadherin (VE-cadherin). J. Cell Biol. 129:203-217.
18. Kemler, R. 1993. From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. Trends Genet. 9:317-321.
19. Tsukita, S., S. Tsukita, A. Nagafuchi, and S. Yonemura. 1992. Molecular linkage between cadherins and actin filaments in cell-cell adherens junctions. Curr. Opin. Cell Biol. 4:834-839.
20. Hulsken, J., J. Behrens, and W. Birchmeier. 1994. Tumor-suppressor gene products in cell contacts: the cadherin-APC-armadillo connection. Curr. Opin. Cell Biol. 6:711-716.
21. Takeichi, M. 1993. Cadherins in cancer: implications for invasion and metastasis. Curr. Opin. Cell Biol. 5:806-811.
22. Frixen, U.H., J. Behrens, M. Sach, G. Eberle, B. Voss, A. Warda, D. Lochner, and W. Birchmeier. 1991. E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J. Cell Biol. 113:173-185.
23. Vleminckx, K., L. Vakaet, M.M. Mareel, W. Fiers, and F. Van Roy. 1991. Genetic manipulation of E-cadherin expression by epithelial tumor reveals an invasion suppressor role. Cell. 66:107-119.
24. Martin-Padura, I., C. de Castellarnau, S. Uccini, E. Pilozzi, P.G. Natali, M.R. Nicotra, F. Ughi, C. Azzolini, E. Dejana, and L. Ruco. 1995. Expression of VE (Vascular Endothelial)-cadherin and other endothelial-specific markers in haemangiomas. J. Pathol. 175:51-57.
25. Navarro, P., L. Caveda, F. Breviario, I. Mandoteanu, M.G. Lampugnani and E. Dejana. 1995. Catenin-dependent and independent functions of vascular endothelial cadherin. J. Biol. Chem. 270:30965-30972.
26. de Lisser, H.M., H.C. Yan, P.J. Newman, W.A. Muller, C.A. Buck, and S.M. Albelda. 1993. Platelet/endothelial cell adhesion molecule-1 (CD31)-mediated cellular aggregation involves cell surface glycosaminoglycans. J. Biol. Chem. 268:16037-16046.
27. Balzac, F., A.M. Belkin, V.E. Koteliansky, Y.V. Bolanov, F. Altruda, L. Silengo, and G. Tarone. 1993. Expression and functional analysis of a cytoplasmic variant of the β1 integrin subunit. J. Cell Biol. 121:171-178.
28. 2+-binding properties of the platelet glycoprotein IIb ligand-interacting domain. J. Biol. Chem. 267:1001-1007.
29. Golay, J., A. Capucci, M. Arsura, M. Castellano, V. Rizzo, M. Introna. 1991. Expression of c-myb and B-myb, but not A-myb, correlates with proliferation in human hematopoietic cells. Blood. 77:149-153.
30. Zanetti, A., G. Conforti, S. Hess, I. Martin-Padura, E. Ghibaudi, K.T. Preissner, and E. Dejana. 1994. Clustering of vitronectin and RGD peptides on microspheres leads to engagement of integrins on the luminal aspect of endothelial cell membrane. Blood. 84:1116-1123.
31. Del Sal, G., M.E. Ruaro, L. Philipson, and C. Schneider. 1992. The growth arrest-specific gene, gas 1, is involved in growth suppression. Cell. 70: 595-607.
32. Vestal, D.J., and B. Ranscht. 1992. Glycosyl Phosphatidylinositol-anchored T-cadherin mediates calcium-dependent, homophilic cell adhesion. J. Cell Biol. 119:451-456.
33. Breier, G., F. Breviario, L. Caveda, R. Berthier, H. Schnurch, U. Gotsch, D. Vestweber, W. Risau, and E. Dejana. 1996. Molecular cloning and expression of murine vascular endothelial-cadherin in early-stage development of cardiovascular system. Blood. 87: 630-641.
34. Muller, W.A., C.M. Ratti, S.L. McDonnell, and Z.A. Conn. 1989. A human endothelial cell-restricted, externally disposed plasmalemmal protein enriched in intercellular junctions. J. Exp. Med. 170:399-414.
35. Lampugnani, M.G., M. Resnati, E. Dejana, and P.C. Marchisio. 1991. The role of integrins in the maintenance of endothelial monolayer integrity. J. Cell Biol. 112:479-490.
36. Arsura, M., M. Introna, F. Passerini, A. Mantovani, and J. Golay. 1992. B-myb antisense oligonucleotides inhibit proliferation of human hematopoietic cell lines. Blood. 79:2708-2716.
37. Ozawa, M., M. Ringwald, and R. Kemler. 1990. Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Proc. Natl. Acad. Sci. USA. 87:4246-4250.
38. Nagafuchi, A., and M. Takeichi. 1990. Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO J. 7:3679-3684.
39. Dejana, E., M.G. Lampugnani, M. Giorgi, M. Gaboli and P.C. Marchisio. 1990. Fibrinogen induces endothelial cell adhesion and spreading via the release of endogenous matrix proteins and the recruitment of more than one integrin receptor. Blood. 75:1509-1517.
40. Rubinfeld, B., B. Souza, I. Albert, O. Muller, S.H. Chamberlain, F.R. Masiark, S. Munemitsu, and P. Polakis. 1993. Association of the APC gene product with β catenin. Science (Wash. DC.). 262:1731-1734.
41. Su, L.K., B. Vogelstein, and K.W. Kinzel. 1993. Association of the APC tumor suppressor gene with catenins. Science (Wash. DC). 262:1734-1737.
42. Heasman, J., A. Crawford, K. Goldstone, P. Garner-Hamrick, B. Gumbiner, P. McCrea, C. Kintner, C.Y. Noro, and C. Wylie. 1994. Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryos. Cell. 79:791-803.
43. Hinck, L., I.S. Nathke, J. Papkoff, and W.J. Nelson. 1994. Beta-catenin: a common target for the regulation of cell adhesion by Wnt-1 and Src signaling pathways. Trends Biochem. Soc. 19:538-542.
44. Watanabe, M., A. Nagafuchi, S. Tsukita, and M. Takeichi. 1994. Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma cell line. J. Cell Biol. 127:247-256.
45. Klymkowsky, M.W., and B. Parr. 1995. The body language of the cells: the intimate connection between cell adhesion and behaviour. Cell. 83:5-8.
46. Faweett, J., C. Buckley, C.L. Holness, I.N. Bird, J.H. Spragg, J. Saunders, A. Harris, and D.L. Simmons. 1995. Mapping the homotypic binding sites in CD31 and the role of CD31 adhesion in the formation of interendothelial cell contacts. J. Cell Biol. 128:1229-1241.