Adrenocorticotropin evokes transient elevations in intracellular free calcium ([Ca2+]i) and increases basal [Ca 2+]i in resting chondrocytes through a phospholipase C-dependent mechanism

Endocrinology

Volumn 146, Issue 7, 2005, Pages 3123-3132

  Evans, Jodi F ^a   Shen, Chwan L ^b   Pollack, Simcha ^a,d   Aloia, John F ^a,c   Yeh, James K ^a,c  

^a WINTHROP UNIVERSITY HOSPITAL   (United States)

^b TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

^c STONY BROOK UNIVERSITY   (United States)

^d ST JOHN'S UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; AGGRECAN; CAFFEINE; CALCIUM ION; COLLAGEN TYPE 2; CORTICOTROPIN; DEXAMETHASONE; FURA 2; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR; RECEPTOR; CALCIUM; CALCIUM CHANNEL; CELL RECEPTOR; CORTICOTROPIN RECEPTOR; ENZYME INHIBITOR; GLUCOCORTICOID; INTERMEDIN; N ACETYL ALPHA INTERMEDIN[4-10]CYCLO[4 NORLEUCINE 5 ASPARTIC ACID 7 [3 (2 NAPHTHYL)ALANINE] 10 LYSINAMIDE]; THAPSIGARGIN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CARTILAGE CELL; CELL ACTIVITY; CELL DIFFERENTIATION; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FLUORESCENCE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HORMONE ACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ANIMAL; CELL LINE; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG RESISTANCE; INTRACELLULAR MEMBRANE; METABOLISM; OSMOLARITY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; CALCIUM; CALCIUM CHANNELS; CELL LINE; CHONDROCYTES; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; ENZYME INHIBITORS; FEMALE; GLUCOCORTICOIDS; INTRACELLULAR MEMBRANES; MELANOCYTE-STIMULATING HORMONES; OSMOLAR CONCENTRATION; PHOSPHOLIPASE C; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CORTICOTROPIN; RECEPTORS, CYTOPLASMIC AND NUCLEAR; THAPSIGARGIN; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 22144465541     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2004-1612     Document Type: Article

References (50)

1. Solomon S 1999 POMC-derived peptides and their biological action. Ann NY Acad Sci 885:22-40
2. Wikberg JE, Muceniece R, Mandrika I, Prusis P, Lindblom J, Post C, Skottner A 2000 New aspects on the melanocortins and their receptors. Pharmacol Res 42:393-420
3. Elias LLK, Huebner A, Metherell LA, Canas A, Warnes GL, Bittis MLM, Cianfaranis S, Clayton PE, Savage MO, Clark AJL 2000 Tall stature in familial glucocorticoid deficiency. Clin Endocrinol (Oxf) 53:423-430
4. Stevens DA, Williams GR 1999 Hormone regulation of chondrocyte differentiation and endochondral bone formation. Mol Cell Endocrinol 151:195-204
5. Evans JF, Niu Q-T, Canas JA, Shen C-L, Aloia JF, Yeh JK 2004 ACTH enhances chondrogenesis in multipotential progenitor cells and matrix production in chondrocytes. Bone 35:96-107
6. Squires GR, Okouneff S, Ionescu M, Poole RA 2003 The pathobiology of focal lesion development in aging human articular cartilage and molecular matrix changes characteristic of osteoarthritis. Arthritis Rheum 48:1261-1270
7. Buckwalter JA, Mankin HJ 1997 Articular cartilage. Part II: Degeneration and osteoarthrosis, repair, regeneration, and transplantation. J Bone Joint Surg Am 79:612-632
8. Johnson KA, van Etten D, Nanda N, Graham RM, Terkeltaub RA 2003 Distinct transglutaminase 2-independent and transglutaminase 2-dependent pathways mediate articular chondrocyte hypertrophy. J Biol Chem 272:18824-18832
9. Jessop DS, Dallman MF, Fleming D, Lightman SL 2001 Resistance to glucocorticoid feedback in obesity. J Clin Endocrinol Metab 86:4109-4114
10. Veldhuis JD, Iranmanesh A, Naftolowitz D, Tatham N, Cassidy F, Carroll BJ 2001 Corticotropin secretory dynamic in humans under low glucocorticoid feedback. J Clin Endocrinol Metab 86:5554-5563
11. Boscara M, Paoletta A, Scarpa E, Barzon L, Fusaro P, Fallo F, Sonino N 1998 Age-related changes in glucocorticoid fast-feedback inhibition of adrenocorticotropin in man. J Clin Endocrinol Metab 83:1380-1383
12. Wilkinson CW, Petrie EC, Murray SR, Colasurdo EA, Raskind MA, Peskind ER 2001 Human glucocorticoid feedback inhibition is reduced in older individuals: evening study. J Clin Endocrinol Metab 86:545-550
13. Purnell JQ, Brandon DD, Isabelle LM, Loriaux DL, Samuels MH 2004 Association of 24-hour cortisol production rates, cortisol-binding, globulin, and plasma-free cortisol levels with body composition, leptin levels, and aging in adult men and women. J Clin Endocrinol Metab 89:281-287
14. Zuscik MJ, D'Souza M, Ionescu AM, Gunter KK, Gunter TE, O'Keefe RJ, Schwarz EM, Puzas JE, Rosier RN 2002 Growth plate chondrocyte maturation is regulated by basal intracellular calcium. Exp Cell Res 276:310-319
15. Parvizi J, Parpura V, Greenleaf JF, Bolander ME 2002 Calcium signaling is required for ultrasound-stimulated aggrecan synthesis by rat chondrocytes. J Orthop Res 21:51-57
16. Gallo-Payet N, Payet MD 2003 Mechanism of action of ACTH: beyond cAMP. Microsc Res Tech 61:275-287
17. Mountjoy KG, Kong PL, Taylor JA, Willard DH, Wilkison WO 2001 Melanocortin receptor-mediated mobilization of intracellular free calcium in HEK293 cells. Physiol Genomics 5:11-19
18. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450
19. 2+ channels with different activation modes and molecular origin in LNCaP human prostate cancer epithelial cells. J Biol Chem 279:30326-30337
20. Fan W, Boston BA, Kesterson RA, Hruby VJ, Cone RD 1997 Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature 385:165-168
21. Zemel, MB, Kim JH, Woychik RP, Michaud EJ, Kadwell SH, Patel IR, Wilkison WO 1995 Agouti regulation of intracellular calcium: Role in the insulin resistance of viable yellow mice. Proc Natl Acad Sci USA 92:4733-4737
22. Kim JH, Mynatt RL, Moore JW, Woychik RP, Moustaid N, Zemel MB 1996 The effects of calcium channel blockade on agouti-induced obesity. FASEB J 10:1646-1652
23. Neves SR, Ram PT, Iyengar R 2002 G protein pathways. Science 296:1636-1639
24. 2+ store. J Biol Chem 276:39161-39170
25. Jan C-R, Ho M-C, Wu S-N, Tseng C-J 1998 The phospho inhibitor U73122 increases cytosolic calcium in MDCK cells by activating calcium influx and releasing stored calcium. Life Sciences 63:895-908
26. Missiaen L, Parys JB, De Smedt H, Himpens B, Casteels R 1994 Inhibition of inositol triphosphate-induced calcium release by caffeine is prevented by ATP. Biochem J 15:81-84
27. 2+ entry channels. J Biol Chem 276:18888-18896
28. Richardson DW, Dodge GR 2003 Dose-dependent effects of corticosteroids on the expression of matrix related genes in normal and cytokine-treated articular chondrocytes. Inflamm Res 52:39-49
29. Ferrari D, Kosher RA 2002 Dlz5 is a positive regulator of chondrocyte differentiation during endochondral ossification. Dev Biol 252:257-270
30. Alford AI, Yellowley CE, Jacobs CR, Donahue HJ 2003 Increases in cytosolic calcium, but not fluid flow, affect aggrecan mRNA levels in articular chondrocytes. J Cell Biochem 90:938-944
31. You J, Reilly GC, Zhen X, Yellowley CE, Chen Q, Donahue HJ, Jacobs CR 2001 Osteopontin gene regulation by oscillatory fluid flow via intracellular calcium mobilization and activation of mitogen-activated protein kinase in MC3T3-E1 osteoblasts. J Biol Chem 276:13365-13371
32. q-11 expression and hormone-stimulated phospholipase C activity in UMR-106-01 cells. Am J Physiol 273:E528-E535
33. 11α protein by dexamethasone in osteoblastic UMR 106-01 cells. Am J Physiol 282:E24-E30
34. Clark AJ, Weber A 1998 Adrenocorticotropin insensitivity syndromes. Endocr Rev 19:828-843
35. Chen AS, Marsh DJ, Trumbauer ME, Frazier EG, Guan X-M, Yu H, Rosenblum CI, Vongs A, Feng Y, Cao L, Metzger JM, Strack AM, Camacho RE, Mellin TN, Nunes CN, Min W, Fisher J, Gopal-Truter S, MacIntyre DE, Chen HY, Van der Ploeg LHT 2000 Inactivation of the mouse melanocortin-3 recpeotr results in increased fat mass and reduced lean body mass. Nat Genet 26:97-102
36. Huszar D, Lynch CA, Fairchild-Huntress V, Dunmore JH, Fang Q, Berkemeier LR, Gu W, Kesterson RA, Boston BA, Cone RD, Smith FJ, Campfield LA, Burn P, Lee F 1997 Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88:131-141
37. Wolff GL, Roberts DW, Mountjoy KG 1999 Physiological consequences of ectopic agouti gene expression: the yellow obese mouse syndrome. Physiol Genomics 1:151-163
38. Strehler EE, Treiman M 2004 Calcium pumps of plasma membrane and cell interior. Curr Mol Med 4:323-335
39. 2+ store with functional properties distinct from those of the endoplasmic reticulum. EMBO J 17:5298-5308
40. Missiaen L, Van Acker K, Van Baelen K, Raeymaekers L, Wuytack F, Parys JB, De Smedt H, Vanoevelen J, Dode L, Rizzuto R, Callewaert G 2004 Calcium release from the Golgi apparatus and the endoplasmic reticulum in HeLa cells stably expressing targeted aequorin to these compartments. Cell Calcium 36:479-487
41. 2+ store in A7r5 and 16HBE140-cells. J Biol Chem 277:6898-6902
42. 2+ store. Cell Calcium 35:115-121
43. Vasquez G, Lievremont J-P, Bird GSJ, Putney JW 2001 Human Trp3 forms both inositol triphosphate receptor-dependent and receptor-independent store-operated cation channels in DT40 avian B lymphocytes. Proc Natl Acad Sci USA 98:11777-11782
44. Bolotina VM 2004 Store-operated channels: diversity and activation mechanisms (web version of Science STKE). www.stke.org/cgi/content/full/ sigtrans;2004/243/pe34
45. 2+ influx factor. Am J Cell Physiol 284:C497-C505
46. Scott CC, Furuya W, Trimble WS, Grinstein S 2003 Activation of store-operated calcium channels. J Biol Chem 278:30534-30539
47. Kinoshita K, Li SJ, Yamazaki M 2001 The mechanism of the stabilization of the hexagonal II (HII) phase in phosphatidylethanolamine membranes in the presence of low concentrations of dimethyl sulfoxide. Eur Biophys J 30:207-220
48. Daleke DL 2003 Regulation of transbilayer plasma membrane phospholipid asymmetry. J Lipid Res 44:233-242
49. Kimple RJ, Jones MB, Shutes A, Yerxa BR, Siderovski DP, Willard FS 2003 Established and emerging fluorescence-based assays for G-protein function: heterotrimeric G-protein α subunits and regulator of G-protein signaling (RGS) proteins. Combinatorial Chem High Throughput Screening 6:1-9
50. Liebman C 2004 G protein-coupled receptors and their signaling pathways: classical therapeutical targets susceptible to novel therapeutic concepts. Curr Pharmaceut Design 10:1937-1958