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Volumn 78, Issue 1, 2005, Pages 27-36

T cells from paroxysmal nocturnal haemoglobinuria (PNH) patients show an altered CD40-dependent pathway

Author keywords

Cytopenia; GPI defective clones; Immune response

Indexed keywords

CD4 ANTIGEN; CD40 ANTIGEN; CD48 ANTIGEN; GAMMA INTERFERON; GLYCAN DERIVATIVE; GLYCOSYLPHOSPHATIDYLINOSITOL; HLA DR ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 2 RECEPTOR ALPHA; PHOSPHATIDYLINOSITOL GLYCAN A; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

EID: 22144434822     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0105026     Document Type: Article
Times cited : (17)

References (57)
  • 1
    • 0024325872 scopus 로고
    • Paroxysmal nocturnal hemoglobinuria
    • Rotoli, B., Luzzatto, L. (1989) Paroxysmal nocturnal hemoglobinuria. Semin. Hematol. 26, 201-207.
    • (1989) Semin. Hematol. , vol.26 , pp. 201-207
    • Rotoli, B.1    Luzzatto, L.2
  • 2
    • 0028884057 scopus 로고
    • The molecular basis of paroxysmal nocturnal hemoglobinuria
    • Rosse, W. F., Ware, R. E. (1995) The molecular basis of paroxysmal nocturnal hemoglobinuria. Blood 86, 3277-3286.
    • (1995) Blood , vol.86 , pp. 3277-3286
    • Rosse, W.F.1    Ware, R.E.2
  • 3
    • 0028299834 scopus 로고
    • Somatic mutations and cell selection in paroxysmal nocturnal hemoglobinuria
    • Bessler, M., Mason, P. J., Luzzato, L. (1994) Somatic mutations and cell selection in paroxysmal nocturnal hemoglobinuria. Lancet 343, 951-953.
    • (1994) Lancet , vol.343 , pp. 951-953
    • Bessler, M.1    Mason, P.J.2    Luzzato, L.3
  • 6
    • 0025784367 scopus 로고
    • Molecular basis of the enhanced susceptibility of the erythrocytes of paroxysmal nocturnal hemoglobinuria to bemolysis in acidified serum
    • Wilcox, L. A., Ezzell, J. L. Bernshaw, N. J., Parker, C. J. (1991) Molecular basis of the enhanced susceptibility of the erythrocytes of paroxysmal nocturnal hemoglobinuria to bemolysis in acidified serum. Blood 78, 820-829.
    • (1991) Blood , vol.78 , pp. 820-829
    • Wilcox, L.A.1    Ezzell, J.L.2    Bernshaw, N.J.3    Parker, C.J.4
  • 8
    • 0029887115 scopus 로고    scopus 로고
    • The dual pathogenesis of paroxysmal nocturnal hemoglobinuria
    • Luzzatto, L., Bessler, M. (1996) The dual pathogenesis of paroxysmal nocturnal hemoglobinuria. Curr. Opin. Hematol. 3, 101-110.
    • (1996) Curr. Opin. Hematol. , vol.3 , pp. 101-110
    • Luzzatto, L.1    Bessler, M.2
  • 9
    • 0030932540 scopus 로고    scopus 로고
    • Somatic mutations in paroxysmal nocturnal hemoglobinuria: A blessing in disguise?
    • Luzzatto, I., Bessler, M., Rotoli, B. (1997) Somatic mutations in paroxysmal nocturnal hemoglobinuria: a blessing in disguise? Cell 88, 1-4.
    • (1997) Cell , vol.88 , pp. 1-4
    • Luzzatto, I.1    Bessler, M.2    Rotoli, B.3
  • 10
    • 0036434172 scopus 로고    scopus 로고
    • The glycosylphosphatidylinositol anchor and paroxysmal nocturnal hemoglobinuria/aplasia model
    • Hall, C., Richards, S. J., Hillmen, P. (2002) The glycosylphosphatidylinositol anchor and paroxysmal nocturnal hemoglobinuria/aplasia model. Acta Haematol. 108, 219-230.
    • (2002) Acta Haematol. , vol.108 , pp. 219-230
    • Hall, C.1    Richards, S.J.2    Hillmen, P.3
  • 11
    • 0033609114 scopus 로고    scopus 로고
    • Clonal population of hematopoietic cell with paroxysmal nocturnal hemoglobinuria phenotype are present in normal individuals
    • Araten, D. J., Nafa, K., Pakdeesuwan, K., Luzzatto, L. (1999) Clonal population of hematopoietic cell with paroxysmal nocturnal hemoglobinuria phenotype are present in normal individuals. Proc. Natl. Acad. Sci. USA 96, 5209-5214.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5209-5214
    • Araten, D.J.1    Nafa, K.2    Pakdeesuwan, K.3    Luzzatto, L.4
  • 12
    • 0030955185 scopus 로고    scopus 로고
    • Murine embrionic stem cells without PIG-A gene activity arc competent for hematopoiesis with the PNH phenotype but not for clonal expansion
    • Rosti, V., Tremml, G., Soares, V., Pandolli, P. P., Luzzatto, L., Bessler, M. (1997) Murine embrionic stem cells without PIG-A gene activity arc competent for hematopoiesis with the PNH phenotype but not for clonal expansion. J. Clin. Invest. 100, 1028-1036.
    • (1997) J. Clin. Invest. , vol.100 , pp. 1028-1036
    • Rosti, V.1    Tremml, G.2    Soares, V.3    Pandolli, P.P.4    Luzzatto, L.5    Bessler, M.6
  • 13
    • 0033230899 scopus 로고    scopus 로고
    • Paroxysmal murine hemoglobinuria (?): A model for human PNH
    • Luzzatto, L. (1999) Paroxysmal murine hemoglobinuria (?): a model for human PNH. Blood 94, 2941-2944.
    • (1999) Blood , vol.94 , pp. 2941-2944
    • Luzzatto, L.1
  • 14
    • 0033819055 scopus 로고    scopus 로고
    • Genetic and environmental effects in paroxysmal nocturnal hemoglobinuria: This little PIG-A goes "Why? Why? Why?"
    • Young, N. S., Maciejewski, J. P. (2000) Genetic and environmental effects in paroxysmal nocturnal hemoglobinuria: this little PIG-A goes "Why? Why? Why?" J. Clin. Invest. 106, 637-641.
    • (2000) J. Clin. Invest. , vol.106 , pp. 637-641
    • Young, N.S.1    Maciejewski, J.P.2
  • 15
    • 0030912049 scopus 로고    scopus 로고
    • The pathophysiology of acquired aplastie anaemia
    • Young, N. S., Maciejewski, J. P. (1997) The pathophysiology of acquired aplastie anaemia. N. Engl. J. Med. 336, 1365-1372.
    • (1997) N. Engl. J. Med. , vol.336 , pp. 1365-1372
    • Young, N.S.1    Maciejewski, J.P.2
  • 16
    • 0031032545 scopus 로고    scopus 로고
    • Clinical characteristics predict response to antilhymocyte globulin in paroxysmal noclurnal haemoglobinuria
    • Paquette, R. L., Yoshimura, R., Veish, C., Kuukel, L., Gajewsky, J., Rosen, P. J. (1997) Clinical characteristics predict response to antilhymocyte globulin in paroxysmal noclurnal haemoglobinuria. Br. J. Haematol. 96, 92-97.
    • (1997) Br. J. Haematol. , vol.96 , pp. 92-97
    • Paquette, R.L.1    Yoshimura, R.2    Veish, C.3    Kuukel, L.4    Gajewsky, J.5    Rosen, P.J.6
  • 17
    • 0024421369 scopus 로고
    • Long-term follow-up of severe aplastic anaemia patients treated with anti-thymocyte globulin
    • Severe aplastic anaemia working party of the European Cooperative Group for Bone Marrow Transplantation (EBMT)
    • De Planque, M. M., Bacigalupo, A., Wursche, A., Hows, J. M., Devergie, A., Frickhofen, N., Brand, A., Nissen, C. (1989) Long-term follow-up of severe aplastic anaemia patients treated with anti-thymocyte globulin. Severe aplastic anaemia working party of the European Cooperative Group for Bone Marrow Transplantation (EBMT). Br. J. Haematol. 73, 121-126.
    • (1989) Br. J. Haematol. , vol.73 , pp. 121-126
    • De Planque, M.M.1    Bacigalupo, A.2    Wursche, A.3    Hows, J.M.4    Devergie, A.5    Frickhofen, N.6    Brand, A.7    Nissen, C.8
  • 19
    • 0034307521 scopus 로고    scopus 로고
    • Abnormal T cell repertoire is consistent with immune process underlying the pathogenesis of paroxysmal nocturnal hemoglobinuria
    • Karadimitris, A., Manavalan, J. S., Thaler, H. T., Notaro, R., Araten, D. J., Nafa, K., Roberts, I. A. G., Weksler, M. E., Luzzatto, L. (2000) Abnormal T cell repertoire is consistent with immune process underlying the pathogenesis of paroxysmal nocturnal hemoglobinuria. Blood 96, 2613-2620.
    • (2000) Blood , vol.96 , pp. 2613-2620
    • Karadimitris, A.1    Manavalan, J.S.2    Thaler, H.T.3    Notaro, R.4    Araten, D.J.5    Nafa, K.6    Roberts, I.A.G.7    Weksler, M.E.8    Luzzatto, L.9
  • 20
    • 0036660175 scopus 로고    scopus 로고
    • Oligoclonal and policlonal CD4 and CO8 lymphocytes in aplastic anemia and paroxysmal nocturnal hemoglobimuria measured by VβCDR3 spectratyping and flow cytometry
    • Risitano, A. M., Kook, H., Zeng, W., Chen, G., Young, N. S., Maciejewski, J. P. (2002) Oligoclonal and policlonal CD4 and CO8 lymphocytes in aplastic anemia and paroxysmal nocturnal hemoglobimuria measured by VβCDR3 spectratyping and flow cytometry. Blood 100, 178-183.
    • (2002) Blood , vol.100 , pp. 178-183
    • Risitano, A.M.1    Kook, H.2    Zeng, W.3    Chen, G.4    Young, N.S.5    Maciejewski, J.P.6
  • 22
    • 0141609073 scopus 로고    scopus 로고
    • Co-stimulatory members of the TNPR family: Keys to effective T-cell immunity?
    • Croft, M. (2003) Co-stimulatory members of the TNPR family: keys to effective T-cell immunity? Nat. Rev. Immunol. 3, 609-620.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 609-620
    • Croft, M.1
  • 24
    • 0029870459 scopus 로고    scopus 로고
    • CD40 expressed on thymic epithelial cells provides costimulatiori for proliferation but not for apoptosis of human thymoeytes
    • Ruggiero, G., Martinez-Cáceres, E., Voordouw, A., Noleboom, E., Graf, D., Kroczek, R. A., Spits, H. (1996) CD40 expressed on thymic epithelial cells provides costimulatiori for proliferation but not for apoptosis of human thymoeytes. J. Immunol. 156, 3737-3746.
    • (1996) J. Immunol. , vol.156 , pp. 3737-3746
    • Ruggiero, G.1    Martinez-Cáceres, E.2    Voordouw, A.3    Noleboom, E.4    Graf, D.5    Kroczek, R.A.6    Spits, H.7
  • 25
    • 0028806723 scopus 로고
    • Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand
    • Grewal, I. S., Xu, J., Flavell, R. A. (1995) Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand. Nature 378, 617-621.
    • (1995) Nature , vol.378 , pp. 617-621
    • Grewal, I.S.1    Xu, J.2    Flavell, R.A.3
  • 26
    • 0031944607 scopus 로고    scopus 로고
    • CD40 and CD154 in cell-mediated immunity
    • Grewal, I. S., Flavell, A. R. (1998) CD40 and CD154 in cell-mediated immunity. Annu. Rev. Immunol. 16, 111-122.
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 111-122
    • Grewal, I.S.1    Flavell, A.R.2
  • 27
    • 2542476167 scopus 로고    scopus 로고
    • CD40/CD154 interactions at the interface of tolerance and immunity
    • Quezada, S. A., Jarvineen, L. Z., Lind, E. F., Noelle, R. J. (2004) CD40/CD154 interactions at the interface of tolerance and immunity. Annu. Rev. Immunol. 22, 307-328.
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 307-328
    • Quezada, S.A.1    Jarvineen, L.Z.2    Lind, E.F.3    Noelle, R.J.4
  • 28
    • 0026479997 scopus 로고
    • The human antigen gp39, a member of the TNK gene family, is a ligand for the CD40 receptor: Expression of a soluble form of die gp39 with B cell co-stinudatory activity
    • Hollenbaugh, D., Grosmaire, L. S., Kullas, C. D., Chalubuy, N. J., Braesch-Andersen, S., Noelle, R. J., Stamenkovic, T., Ledbetter, J. A., Aruffo, A. (1992) The human antigen gp39, a member of the TNK gene family, is a ligand for the CD40 receptor: expression of a soluble form of die gp39 with B cell co-stinudatory activity. EMBO J. 11, 4313-4321.
    • (1992) EMBO J. , vol.11 , pp. 4313-4321
    • Hollenbaugh, D.1    Grosmaire, L.S.2    Kullas, C.D.3    Chalubuy, N.J.4    Braesch-Andersen, S.5    Noelle, R.J.6    Stamenkovic, T.7    Ledbetter, J.A.8    Aruffo, A.9
  • 29
    • 0027293241 scopus 로고
    • The regulation of the expression of gp39. The CD40 ligand, on normal and cloned CD4+ T cells
    • Roy, M., Waldschmidt, T., Aruffo, A., Ledbeller, J. A., Noelle, R. J. (1993) The regulation of the expression of gp39. the CD40 ligand, on normal and cloned CD4+ T cells. J. Immunol. 151, 2497-2510.
    • (1993) J. Immunol. , vol.151 , pp. 2497-2510
    • Roy, M.1    Waldschmidt, T.2    Aruffo, A.3    Ledbeller, J.A.4    Noelle, R.J.5
  • 30
    • 0031828709 scopus 로고    scopus 로고
    • Functional competence of T cells in the absence of glycosylphosphatidylinositol-anchored proteins caused by T cell-specific disruption of the Pig-A gene
    • Takahama, Y., Ohishi, K., Tokoro, Y., Sugawara, T., Yoshinnira, Y., Okabe, M., Kinoshita, T., Takeda, J. (1998) Functional competence of T cells in the absence of glycosylphosphatidylinositol-anchored proteins caused by T cell-specific disruption of the Pig-A gene. Eur. J. Immunol. 28, 2159-2166.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2159-2166
    • Takahama, Y.1    Ohishi, K.2    Tokoro, Y.3    Sugawara, T.4    Yoshinnira, Y.5    Okabe, M.6    Kinoshita, T.7    Takeda, J.8
  • 31
    • 0023225925 scopus 로고
    • Removal of lymphocyte surface molecules with phosphatidylinositol- specific phospholipase C: Effects on mitogen responses and evidence that ThB and certain Qa antigens are membrane-anchored via phosphatidylinositol
    • Stiernberg, J., Low, M. G., Flaherty, L., Kincade, P. W. (1987) Removal of lymphocyte surface molecules with phosphatidylinositol-specific phospholipase C: effects on mitogen responses and evidence that ThB and certain Qa antigens are membrane-anchored via phosphatidylinositol. J. Immunol. 138, 3877-3884.
    • (1987) J. Immunol. , vol.138 , pp. 3877-3884
    • Stiernberg, J.1    Low, M.G.2    Flaherty, L.3    Kincade, P.W.4
  • 32
    • 0025157628 scopus 로고
    • Role of phosphatodylinositol-anchored proteins in T cell activation
    • Presky, D. H., Low, M. G., Shevach, E. M. (1990) Role of phosphatodylinositol-anchored proteins in T cell activation. J. Immunol. 144, 860-808.
    • (1990) J. Immunol. , vol.144 , pp. 860-1808
    • Presky, D.H.1    Low, M.G.2    Shevach, E.M.3
  • 33
    • 0025328147 scopus 로고
    • Inhibition of Ly-6A antigen expression prevents T cell activation
    • Flood, P. M., Douherty, J. P., Ron, Y. (1990) Inhibition of Ly-6A antigen expression prevents T cell activation. J. Exp. Med. 172, 115-120.
    • (1990) J. Exp. Med. , vol.172 , pp. 115-120
    • Flood, P.M.1    Douherty, J.P.2    Ron, Y.3
  • 34
    • 0032878539 scopus 로고    scopus 로고
    • Analysis of T cells in paroxysmal nocturnal hemoglobinuria provides direct evidence that thymic T-cell production declines with age
    • Richards, S. J., Morgan, G. J., Hillmen, P. (1999) Analysis of T cells in paroxysmal nocturnal hemoglobinuria provides direct evidence that thymic T-cell production declines with age. Blood. 94, 2790-2799.
    • (1999) Blood , vol.94 , pp. 2790-2799
    • Richards, S.J.1    Morgan, G.J.2    Hillmen, P.3
  • 35
    • 0026771308 scopus 로고
    • Differences in activation of normal and glycosilphosphatidylinositol- negative lymphocytes derived from patients with paroxysmal nocturnal hemoglobinnria
    • Schubert, J., Uciechowski, P., Zielinska-Skowronek, M., Tietjen, C., Leo, R., Schmidt, R. K. (1992) Differences in activation of normal and glycosilphosphatidylinositol-negative lymphocytes derived from patients with paroxysmal nocturnal hemoglobinnria. J. Immunol. 148, 3814-3819.
    • (1992) J. Immunol. , vol.148 , pp. 3814-3819
    • Schubert, J.1    Uciechowski, P.2    Zielinska-Skowronek, M.3    Tietjen, C.4    Leo, R.5    Schmidt, R.K.6
  • 36
    • 0032836138 scopus 로고    scopus 로고
    • Defective TCR signaling events in glycosilphosphatidylinositol-deficient T cells derived from paroxysmal nocturnal hemoglobinuria patients
    • Romagnoli, P., Bron, C. (1999) Defective TCR signaling events in glycosilphosphatidylinositol-deficient T cells derived from paroxysmal nocturnal hemoglobinuria patients. Int. Immunol. 11, 1411-1422.
    • (1999) Int. Immunol. , vol.11 , pp. 1411-1422
    • Romagnoli, P.1    Bron, C.2
  • 37
    • 0029748586 scopus 로고    scopus 로고
    • Blood cell flow cytometry in paroxysmal nocturnal hemoglobinuria: A tool for measuring the extent of PNH clone
    • Alfinito, F., Del Vecchio, L., Rocco, S., Musto, P., Rotoli, B. (1996) Blood cell flow cytometry in paroxysmal nocturnal hemoglobinuria: a tool for measuring the extent of PNH clone. Leukemia 10, 1326-1330.
    • (1996) Leukemia , vol.10 , pp. 1326-1330
    • Alfinito, F.1    Del Vecchio, L.2    Rocco, S.3    Musto, P.4    Rotoli, B.5
  • 38
    • 0033836378 scopus 로고    scopus 로고
    • Application of cytometry to the diagnosis of paroxysmal nocturnal hemoglobinuria
    • Richards, S. J., Rawstron, A. C., Hillmen, P. (2000) Application of cytometry to the diagnosis of paroxysmal nocturnal hemoglobinuria. Cytometry 42, 223-233.
    • (2000) Cytometry , vol.42 , pp. 223-233
    • Richards, S.J.1    Rawstron, A.C.2    Hillmen, P.3
  • 40
    • 0032712575 scopus 로고    scopus 로고
    • Divided we stand: Tracking cell proliferation with carboxyfluorescein diacetate succinimidyl ester
    • Lyons, A. B. (1999) Divided we stand: tracking cell proliferation with carboxyfluorescein diacetate succinimidyl ester. Immunol. Cell Biol. 77, 509-515.
    • (1999) Immunol. Cell Biol. , vol.77 , pp. 509-515
    • Lyons, A.B.1
  • 41
    • 0034699367 scopus 로고    scopus 로고
    • Analyzing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution
    • Lyons, A. B. (2000) Analyzing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution. J. Immunol. Methods 243, 147-151.
    • (2000) J. Immunol. Methods , vol.243 , pp. 147-151
    • Lyons, A.B.1
  • 42
    • 0023481311 scopus 로고
    • Induction of T cell proliferation with anti-CD3 switch-variant monoclonal antibodies: Effect of heavy chain isotype in monocyte-dependent systems
    • Van Lier, R. A. W., Bool, J. H., De Groot, F. R., Aarden, L. A. (1987) Induction of T cell proliferation with anti-CD3 switch-variant monoclonal antibodies: effect of heavy chain isotype in monocyte-dependent systems. Eur. J. Immunol. 17, 1599-1604.
    • (1987) Eur. J. Immunol. , vol.17 , pp. 1599-1604
    • Van Lier, R.A.W.1    Bool, J.H.2    De Groot, F.R.3    Aarden, L.A.4
  • 43
    • 0029148642 scopus 로고
    • Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow eytomelry
    • Picker, L. J., Singh, M. K., Treer, J. R., Waldorp, S. L. (1995) Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow eytomelry. Blood 86, 1408-1419.
    • (1995) Blood , vol.86 , pp. 1408-1419
    • Picker, L.J.1    Singh, M.K.2    Treer, J.R.3    Waldorp, S.L.4
  • 44
    • 0027056241 scopus 로고
    • Molecular interactions mediating T-B lymphocyte collaboration in human lymphoid follicles. Roles of T cell-B-cell-activating molecule (5c8 antigen) and CD40 in contact-dependent help
    • Lederman, S., Yellin, M. J., Inghiorami, G., Lee, J. J., Knowles, D. M., Chess, L. (1992) Molecular interactions mediating T-B lymphocyte collaboration in human lymphoid follicles. Roles of T cell-B-cell-activating molecule (5c8 antigen) and CD40 in contact-dependent help. J. Immunol. 149, 3817-3826.
    • (1992) J. Immunol. , vol.149 , pp. 3817-3826
    • Lederman, S.1    Yellin, M.J.2    Inghiorami, G.3    Lee, J.J.4    Knowles, D.M.5    Chess, L.6
  • 45
    • 0030210233 scopus 로고    scopus 로고
    • Different CD40-mediated signaling events require distinct CD40 structural features
    • Hostager, B. S., Hsing, Y., Harms, D. E., Bishop, G. A. (1996) Different CD40-mediated signaling events require distinct CD40 structural features. J. Immunol. 157, 1047-1053.
    • (1996) J. Immunol. , vol.157 , pp. 1047-1053
    • Hostager, B.S.1    Hsing, Y.2    Harms, D.E.3    Bishop, G.A.4
  • 46
    • 0036740354 scopus 로고    scopus 로고
    • Glyeosylphosphatidylinositol-linked proteins are required for maintenance of a normal peripheral lymplioid compartment but not for lymphocyte development
    • Bessler, M., Rosti, V., Peng, Y., Cattoretti, G., Notaro, R., Ohsako, S., Elkon, K. B., Luzzatto, L. (2002) Glyeosylphosphatidylinositol-linked proteins are required for maintenance of a normal peripheral lymplioid compartment but not for lymphocyte development. Eur. J. Immunol. 32, 2607-2616.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 2607-2616
    • Bessler, M.1    Rosti, V.2    Peng, Y.3    Cattoretti, G.4    Notaro, R.5    Ohsako, S.6    Elkon, K.B.7    Luzzatto, L.8
  • 49
    • 2342492829 scopus 로고    scopus 로고
    • Lipid raft domains and protein networks in T-cell receptor signal transduction
    • Harder, T. (2004) Lipid raft domains and protein networks in T-cell receptor signal transduction. Curr. Opin. Immunol. 16, 353-359.
    • (2004) Curr. Opin. Immunol. , vol.16 , pp. 353-359
    • Harder, T.1
  • 52
    • 2342500829 scopus 로고    scopus 로고
    • New views of the immunological synapse: Variations in assembly and function
    • Jacobelli, J., Andres, P. G., Boisvert, J., Kruinmel, M. K. (2004) New views of the immunological synapse: variations in assembly and function. Curr. Opin. Immunol. 16, 345-352.
    • (2004) Curr. Opin. Immunol. , vol.16 , pp. 345-352
    • Jacobelli, J.1    Andres, P.G.2    Boisvert, J.3    Kruinmel, M.K.4
  • 53
    • 0036173059 scopus 로고    scopus 로고
    • A CD40 signalosome anchored in lipid rafts leads to constitutive; activation of NF-κB and autonomous cell growth B cell lymphoma
    • Pham, L. V., Tamayo, A. T., Yoshimura, L. C., Lo, P., Terry, N., Reid, P. S., Ford, R. J. (2002) A CD40 signalosome anchored in lipid rafts leads to constitutive; activation of NF-κB and autonomous cell growth B cell lymphoma. Immunity 16, 37-50.
    • (2002) Immunity , vol.16 , pp. 37-50
    • Pham, L.V.1    Tamayo, A.T.2    Yoshimura, L.C.3    Lo, P.4    Terry, N.5    Reid, P.S.6    Ford, R.J.7
  • 55
    • 0029862164 scopus 로고    scopus 로고
    • Increased expression of CD40 ligand on systemic lupus erythematosous lymphocytes
    • Koshy, M., Berger, D., Crow, M. K. (1996) Increased expression of CD40 ligand on systemic lupus erythematosous lymphocytes. J. Clin. Invest. 98, 826-837.
    • (1996) J. Clin. Invest. , vol.98 , pp. 826-837
    • Koshy, M.1    Berger, D.2    Crow, M.K.3
  • 56
    • 0034292397 scopus 로고    scopus 로고
    • + T lymphocytes with constitutive CD40 ligand in preimmune (NZB×NZW)F1 lupus-prone mice: Phenotype and possible role in autoreactivity
    • + T lymphocytes with constitutive CD40 ligand in preimmune (NZB×NZW)F1 lupus-prone mice: phenotype and possible role in autoreactivity. J. Immunol. 165, 4095-4104.
    • (2000) J. Immunol. , vol.165 , pp. 4095-4104
    • Ixitesjo, H.1    Burd, G.P.2    Mageed, R.A.3
  • 57
    • 0034793917 scopus 로고    scopus 로고
    • Limited heterogeneity of T cell receptor BV usage in aplastic anaemia
    • Zeng, W., Maciejewski, J. P., Chen, G., Young, N. S. (2001) Limited heterogeneity of T cell receptor BV usage in aplastic anaemia. J. Clin. Invest. 108, 765-773.
    • (2001) J. Clin. Invest. , vol.108 , pp. 765-773
    • Zeng, W.1    Maciejewski, J.P.2    Chen, G.3    Young, N.S.4


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