Adiponectin receptor 2 expression in liver and insulin resistance in db/db mice given a β3-adrenoceptor agonist

European Journal of Pharmacology

Volumn 518, Issue 1, 2005, Pages 71-76

  Oana, Fumiki ^a   Takeda, Hiroo ^a   Matsuzawa, Akane ^a   Akahane, Satoshi ^a   Isaji, Masayuki ^a   Akahane, Masuo ^a  

^a KISSEI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

3 aderenoceptor agonist; Adiponectin; Adiponectin receptor 1; Adiponectin receptor 2

Indexed keywords

5 [2 [[2 (3 CHLOROPHENYL) 2 HYDROXYETHYL]AMINO]PROPYL] 1,3 BENZODIOXOLE 2,2 DICARBOXYLIC ACID; ADIPONECTIN; ADIPONECTIN RECEPTOR 1; ADIPONECTIN RECEPTOR 2; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; CYTOKINE RECEPTOR; FATTY ACID; GLUCOSE; HEMOGLOBIN A1C; INSULIN; MESSENGER RNA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; DRUG EFFECT; EPIDIDYMIS FAT; FATTY ACID BLOOD LEVEL; GENE EXPRESSION; GENE EXPRESSION REGULATION; GLUCOSE BLOOD LEVEL; HEMOGLOBIN DETERMINATION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LIVER; MALE; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RECEPTOR DOWN REGULATION; RNA ANALYSIS; SOLEUS MUSCLE; TISSUE LEVEL; TRIACYLGLYCEROL BLOOD LEVEL; WHITE ADIPOSE TISSUE;

ADIPONECTIN; ADIPOSE TISSUE; ADRENERGIC BETA-AGONISTS; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; DIABETES MELLITUS, TYPE 2; DIOXOLES; EATING; FATTY ACIDS; GENE EXPRESSION; GLUCOSE TOLERANCE TEST; HEMOGLOBIN A, GLYCOSYLATED; INSULIN; INSULIN RESISTANCE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; OBESITY; RECEPTORS, ADRENERGIC, BETA-3; RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS;

EID: 22044436805     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.06.004     Document Type: Article

References (17)

1. A.H. Berg, T.P. Combs, and P.E. Scherer ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism Trends Endocrinol. Metab. 13 2002 84 89
2. A.E. Civitarese, C.P. Jenkinson, D. Richard, M. Bajal, K. Cusi, S. Kashyap, R. Berria, R. Belfort, R.A. DeFronzo, L.J. Mandarino, and E. Ravussin Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of type 2 diabetes Diabetologia 47 2004 816 820
3. S. Collins, K.W. Daniel, and E.M. Rohlfs Depressed expression of adipocyte beta-aderenergic receptors is a common feature of congenital and diet-induced obesity in rodents Int. J. Obes. Relat. Metab. Disord. 23 1999 669 677
4. C. Debard, M. Laville, V. Berbe, E. Loizon, C. Guillet, B. Morio-Liondore, Y. Boirie, and H. Vidal Expression of key genes of fatty acid oxidation, including adiponectin receptors, in skeletal muscle of type 2 diabetic patients Diabetologia 47 2004 917 925
5. S.T. Ding, B.H. Liu, and Y.H. Ko Cloning and expression of porcine adiponectin and adiponectin receptor 1 and 2 genes in pigs J. Anim. Sci. 82 2004 3162 3174
6. P.J. Haval Update on adipocyte hormones: regulation of energy balance and carbohydrate/lipid metabolism Diabetes 53 2004 143 151
7. H. Hirose, T. Kawai, Y. Yamamoto, M. Taniyama, M. Tomita, K. Matsubara, Y. Okazaki, T. Ishii, Y. Oguma, I. Takei, and T. Saruta Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with type 2 diabetes Metabolism 51 2002 314 317
8. K. Hotta, T. Funahashi, Y. Arita, M. Takahashi, M. Matsuda, Y. Okamoto, H. Iwahashi, H. Kuriyama, N. Ouchi, K. Maeda, M. Nishida, S. Kihara, N. Sakai, T. Nakajima, K. Hasegawa, M. Muraguchi, Y. Ohmoto, T. Nakamura, S. Yamashita, T. Hanafusa, and Y. Matsuzawa Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients Arterioscler. Thromb. Vasc. Biol. 20 2000 1595 1599
9. K. Hotta, T. Funahashi, N.L. Bodkin, H.K. Ortmeyer, Y. Arita, B.C. Hansen, and Y. Matsuzawa Circulating concentrations of adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys Diabetes 50 2001 1126 1133
10. H. Kato, M. Ohue, K. Kato, A. Nomura, K. Toyosawa, Y. Furutani, S. Kimura, and T. Kadowaki Mechanism of amelioration of insulin resistance by beta 3-adrenoceptor agonist AJ-9677 in the KK-Ay/Ta diabetic obese mouse model Diabetes 50 2001 113 122
11. X. Liu, F. Perusse, and L.J. Bukowiecki Mechanism of the antidiabetic effects of the beta 3-adrenergic agonist CL-316,243 in obese Zucker-ZDF rats Am. J. Physiol. 274 1998 R1212 R1219
12. N. Maeda, M. Takahashi, T. Funahashi, S. Kihara, H. Nishizawa, K. Kishida, H. Nagaretani, M. Matsuda, R. Komuro, N. Ouchi, H. Kuriyama, K. Hotta, T. Nakamura, I. Shimomura, and Y. Matsuzawa PPARgamma ligands increase expression and plasma concentration of adiponectin, an adipose-derived protein Diabetes 50 2001 2094 2099
13. K.L. Pierce, R.T. Premont, and R.J. Lefkowits Seven-transmembrane receptors Nat. Rev., Mol. Cell Biol. 3 2002 639 650
14. V.S. Susulic, R.C. Frederich, J. Lawitts, E. Tozzo, B.B. Kahn, M.E. Harper, J. Himms-Hagen, J.S. Flier, and B.B. Lowell Targeted disruption of the beta 3-adrenergic receptor gene J. Biol. Chem. 270 1995 29483 29492
15. O. Ukkola, and M. Santaniemi Adiponectin: a link between excess adiposity and associated comorbidities J. Mol. Med. 80 2002 696 702
16. T. Yamauchi, J. Kamon, Y. Ito, A. Tsuchida, T. Yokomizo, S. Kita, T. Sugiyama, M. Miyagishi, K. Hara, M. Tsunoda, K. Murakami, T. Ohteki, S. Uchda, S. Takekawa, H. Waki, N.H. Tsuno, Y. Shibata, Y. Terauchi, P. Froguel, K. Tobe, S. Koyasu, K. Taira, T. Kitamura, T. Shimizu, R. Nagai, and T. Kadowaki Cloning of adiponectin receptors that mediate antidiabetic metabolic effects Nature 423 2003 762 769
17. Y. Zhang, M. Matheny, S. Zolotukhin, N. Tumer, and P.J. Scarpace Regulation of adiponectin and leptin gene expression in white and brown adipose tissue: influence of beta3-adrenergic agonists, retinoic acid, leptin and fasting Biochim. Biophys. Acta 1584 2002 115 122