Effect of leptin on proliferation and apoptosis in human gastric cancer cell line SGC7901

Fudan University Journal of Medical Sciences

Volumn 32, Issue 1, 2005, Pages 47-50

  Zhao, Xiao Long ^a   Zhu, Zhao Hua ^a   Huang, Kai Hong ^a   Xia, Zhong Sheng ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Apoptosis; Gastric cancer; Leptin; Leptin receptor

Indexed keywords

LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA; PROTEIN BAX;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL LINE; CELL PROLIFERATION; CELL STRAIN SGC7901; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER;

EID: 21844457645     PISSN: 16728467     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Calle EE, Rodriguez C, Walker-Thurmond K, et al. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med, 2003, 348(17):1625
2. Konopleve BM, Mikhail A, Estrov Z, et al. Expression and function of leptin receptor isoforms in myeloid leukemia and myelodysplastic syndromes: proliferative and anti-apoptotic activities. Blood, 1999, 93(5):1668
3. Attoub S, Noe V, Pirola L, et al. Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways. FASEB J, 2000, 14 (14):2329
4. Sierra-Honigmann MR, Nath AK, Murakami C, et al. Biological action of leptin as an angiogenic. Science, 1998, 281(5383):1683
5. Hardwick JC, Van Den Brink GR, Offerhaus GJ, et al. Leptin is a growth factor for colonic epithelial cells. Gastroenterology, 2001 121 (1):79
6. Schnerder R, Bornstein SR, Chrousos GP, et al. Leptin mediates a proliferative response in human gastric mucosa cells with functional receptor. Horm Metab Res, 2001, 33(1):1
7. Azuma T, Suto H, Ito Y, et al. Gastric leptin and helicobacter pylori infection. Gut, 2001, 49(3):324
8. Mix H, Widjaja A, Jandl O, et al. Expression of leptin and leptin receptor isoforms in the human stomach. Gut, 2000, 47(4):481