Serum withdrawal and etoposide induce apoptosis in human lung carcinoma cell line A549 via distinct pathways

Apoptosis

Volumn 2, Issue 2, 1997, Pages 199-206

  Huang, Y ^a   Chan, A M L ^b   Liu, Y ^a   Wang, X ^a   Holbrook, N J ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b MOUNT SINAI MEDICAL CENTER   (United States)

Author keywords

Apoptosis; ERK; JNK; p53; Rb

Indexed keywords

EID: 0000534187     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026420616484     Document Type: Article

References (30)

1. Williams GT, Smith CA. Molecular regulation of apoptosis: genetic controls on cell death. Cell 1993; 74: 777-779.
2. Vaux DL. Toward an understanding of the molecular mechanisms of physiological cell death. Proc Natl Acad Sci USA 1993; 90: 786-789.
3. Wyllie AH, Kerr JFR, Currie AR. Cell death: the significance of apoptosis. Int Rev Cytol 1980; 68: 251-306.
4. White E. Life, death, and the pursuit of apoptosis. Genes Dev 1996; 10: 1-15.
5. Araki S, Simada Y, Kaji K, Hayashi H. Role of protein kinase C in the inhibition by fibroblast growth factor of apoptosis in serum-depleted endothelial cells. Biochem Biophys Res Commun 1990; 168: 1194-1200.
6. Geier A, Haimshon M, Berry R, Hemi R, Lunenfeld B. Insulin-like growth factor-1 inhibits cell death induced by cycloheximide in MCF-7 cells: a model system for analyzing control of cell death. In Vitro Cell Dev Bio 1992; 28: 725-729.
7. Kyprianou N, English HF, Davidson NE, Isaacs JT. Programmed cell death during regression of the MCF-7 human breast cancer following estrogen ablation. Cancer Res 1991; 51: 161-166.
8. Raff M. Social controls on cell survival and cell death. Nature 1992; 356: 397-400.
9. Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995; 270: 1326-1331.
10. Liebermann DA, Hoffman B, Steinman RA Molecular controls of growth arrest and apoptosis: p53-dependent and independent pathways. Oncogene 1995; 11: 199-210.
11. Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig RW. Participation of p53 protein in the cellular response to DNA damage. Cancer Res 1991; 51: 6304-6311.
12. Zhan Q, Carrier F, Fornace AJ Jr. Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol Cell Biol 1993; 13: 4242-4250.
13. El-Diety WS, Harper JW, O'Connor PM, et al. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res 1994; 54: 1169-1174.
14. Kastan MB, Zhan Q, El-Diety WS, et al. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia, Cell 1992; 71: 587-597.
15. Chen C-Y, Oliner JD, Zhan AJ, Fornace AJ Jr, Vogelstein B, Kastan MB. Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway. Proc Natl Acad Sci 1994; 91: 2684-2688.
16. Oltvai ZN, Molliman CL, Korsmeyer SJ. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993; 74: 609-619.
17. Kyriakis JM, Woodgett JR, Avruch J. The stress-activated protein kinases. A novel ERK subfamily responsive to cellular stress and inflammatory cytokines. Ann NY Acad Sci 1995; 7: 766: 303-319.
18. Zanke BW, Boudreau K, Rubie E, et al. The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat. Current Biol 1996; 6: 606-613.
19. Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer S. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1990; 348: 334-336.
20. Lowe SW, Ruley HE, Jack T, Housman DE. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 1993; 74: 957-967.
21. Liu Y, Gorospe M, Yang C, Holbrook NJ. Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP-1-dependent gene activation. J Biol Chem 1995; 270: 8377-8380.
22. Kyriakis JM, Banerjee P, Nikolakaki E, et al. The stress-activated protein kinases. The stress-activated protein kinase subfamily of c-Jun kinases. Nature 1994; 369: 156-160.
23. Bender RA, Hamel E, Hande KR In: Chabner BA, Collins JM, eds. Cancer Chemotherapy: Principles and Practice. Philadelphia, PA (USA): J. B. Lippincott Co, 1990: 253-275.
24. Lehman TA, Bennett WP, Metcalf RA, et al. p53 mutations, ras mutations, and p53-heat shock 70 protein complexes in human lung carcinoma cell lines. Cancer Res 1991; 51: 4090-4096.
25. An B, Dou QP. Cleavage of retinoblastoma protein during apoptosis: an interleukin 1 beta-converting enzyme-like protease as candidate. Cancer Res 1996; 56: 438-442.
26. Waldman T, Lengauer C, Kinzler KW, Volgestein B. Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 1996; 381: 713-716.
27. Wang J, Walsh K. Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation. Science 1996; 273: 359-361.
28. Polyak K, Waldman T, He T-C, Kinder KW, Vogelstein B. Genetic determinants of p53-induced apoptosis and growth arrest. Gene Dev 1996; 10: 1945-1952.
29. Gorospe M, Wang X, Guyton KZ, Holbrook NJ. Mol Cell Biol 1996; 16: 6654-6660.
30. Nevins JR. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science 1992; 258: 424-429.