Identification, characterization and structure of a new Delta class glutathione transferase isoenzyme

Biochemical Journal

Volumn 388, Issue 3, 2005, Pages 763-771

  Udomsinprasert, Rungrutai ^a   Pongjaroenkit, Saengtong ^b   Wongsantichon, Jantana ^a   Oakley, Aaron J ^c   Prapanthadara, La Aied ^d   Wilce, Matthew C J ^c   Ketterman, Albert J ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

^b MAEJO UNIVERSITY   (Thailand)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^d CHIANG MAI UNIVERSITY   (Thailand)

Author keywords

Anopheles dirus; Crystal structure; Delta class glutathione transferase; Enzyme characterization; Glutathione transferase gene; Regulatory element

Indexed keywords

BIOCHEMISTRY; CHARACTERIZATION; CRYSTAL STRUCTURE; FATTY ACIDS; GENES; INSECTICIDES; TOPOLOGY;

ANOPHELES DIRUS; ENZYME ACTIVITIES; GLUTATHIONE TRANSFERASE (GST) ISOENZYMES; MALARIA;

ENZYMES;

CHLORPHENOTANE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE DELTA5 5; INSECTICIDE; ISOENZYME; UNCLASSIFIED DRUG;

ANOPHELES; ANOPHELES DIRUS; ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBSTRATE; FEMALE; INSECT; MOSQUITO; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; ANOPHELES; BASE SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DNA, COMPLEMENTARY; ELECTROSTATICS; GENOMICS; GLUTATHIONE TRANSFERASE; ISOENZYMES; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROTEIN CONFORMATION; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

ANOPHELES DIRUS; INSECTA;

EID: 21744436950     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20042015     Document Type: Article

References (38)

1. Ding, Y., Ortelli, F., Rossiter, L. C., Hemingway, J. and Ranson, H. (2003) The Anopheles gambiae glulathione transferase supergene family; annotation, phylogeny and expression profiles. BMC Genomics 4, 35-50
2. Vontas, J. G., Small, G. J. and Hemingway, J. (2001) Glutathione S-transferases as antioxidant defence agents confer pyrethroid resistance in Nilaparvata lugens. Biochem. J. 357, 65-72
3. Zou, S., Meadows, S., Sharp, L., Jan, L. Y. and Jan, Y. N. (2000) Genome-wide study of aging and oxidative stress response in Drosophila melanogaster. Proc. Natl. Acad. Sci. U.S.A. 97, 13726-13731
4. Prapanthadara, L., Hemingway, J. and Ketterman, A. J. (1993) Partial purification and characterization of glutathione S-transferases involved in DOT resistance from the mosquito Anopheles gambiae. Pestic. Biochem. Physiol. 47, 119-133
5. Oakley, A. J., Harnnoi, T., Udornsinprasert, R., Jirajaroenrat, K., Ketterman, A. J. and Wilce, M. C. J. (2001) The crystal structures of glutathione S-transferases isozymes 1-3 and 1-4 from Anopheles dirus species B. Protein Sci, 10, 2176-2185
6. Jirajaroenrat, K., Pongjaroenkit, S., Krittanai, C., Prapanthadara, L. and Ketterman, A. J. (2001) Heterologous expression and characterization of alternatively spliced glutathione S-transferases from a single Anopheles gene. Insect Biochem Mol Biol. 31, 867-875
7. Pongjaroenkit, S., Jirajaroenrat K., Boonchauy, C., Chanama, U., Leetachewa, S., Prapanthadara, L. and Ketterman, A. J. (2001) Genomic organization and putative promoters of highly conserved glutathione S-transferases originating by alternative splicing in Anopheles dirus. Insect Biochem. Mol. Biol. 31, 75-85
8. Udomsinprasert, R. and Ketterrran, A. J. (2002) Expression and characterization of a novel class of glutathione S-transferase from Anopheles dirus. Insect Biochem. Mol. Biol. 32, 425-433
9. Mannervik, B., Awasthi, Y. C., Board, P. G., Hayes, J. D., Di Ilio, C., Ketterer, B., Listowsky, I., Morgenstern, R., Muramatsu, M., Pearson, W. R. et al. (1992) Nomenclature for human glutathione transferases. Biochem. J. 282, 305-306
10. Chelvanayagam, G., Parker, M. W. and Board, P. G. (2001) Fly fishing for GSTs: a unified nomenclature for mammalian and insect glutathione transferases. Chem. Biol. Interact. 133, 256-260
11. Ketterman, A. J., Prommeenate, P., Boonchauy, C., Chanama, U., Leetachewa, S. Promtet, N. and Prapanthadara, L. (2001) Single amino acid changes outside the active site significantly affect activity of glutathione S-transferases. Insect Biochem. Mol. Biol. 31, 65-74
12. Prapanthadara, L., Koottathep, S., Promtet, N., Hemingway, J. and Ketterman, A. J. (1996) Purification and characterization of a major glutathione S-transferase from the mosquito Anopheles dirus (species B). Insect Biochem. Mol. Biol. 26, 277-285
13. Wendel, A. (1981) Glutathione petroxidase. Methods Enzymol. 77, 325-333
14. Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254
15. Vagin, A. and Teplyakov, A. (2000) An approach to multi-copy search in molecular replacement. Acta Crystallogr. Sect. D Biol. Crystallogr. 56, 1622-1624
16. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Gross-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S. et al. (1998) Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr. Sect. D Biol. Crystallogr. 54, 905-921
17. Jones, T. A., Zou, J. Y., Cowan, S. W. and Kjeldgaard, M. (1991) Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. Sect. A Found. Crystallogr. 47, 110-119
18. Guex, N. and Peitsch, M. C. (1997) SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis 18, 2714-2723
19. Ranson, H., Collins, F. and Hemingway, J. (1998) The role of alternative mRNA splicing in generating heterogeneity within the Anopheles gambiae class I glutathione S-transferase family. Proc. Natl. Acad. Sci. U.S.A. 95, 14284-14289
20. Lougarre, A., Bride, J. M. and Fournier, D. (1999) Is the insect glutathione S-transferase I gene family intronless? Insect Mol Biol. 8, 141-143
21. Smith, R., Wiese, B., Wojzynski, M., Davison, D. and Worley, K. (1996) BCM search launcher - an integrated interface to molecular biology data base search and analysis services available on the World Wide Web. Genome Res. 6, 454-462
22. Jeng, S. S., Wan, W. C. and Chang, C. F. (1978) Existence of an estrogen-like compound in the ovary of the shrimp Parapenaeus lissurus. Gen. Comp. Endocrinol. 36, 211-214
23. Ziegler, R. and Ibrahim, M. M. (2001) Formation of lipid reserves in fat body and eggs of the yellow fever mosquito, Aedes aegypti. J. Insect Physiol. 47, 623-627
24. Briegel, H., Gut, T. and Lea, A. O. (2003) Sequential deposition of yolk components during oagenesis in an insect, Aedes aegypti (Diptera: Culicidae). J. Insect Physiol. 49, 249-260
25. Leaver, M. J., Wright, J. and George, S. G. (1997) Structure and expression of a cluster of glutathione S-transferase genes from a marine fish, the plaice (Pleuronectes platessa). Biochem. J. 321, 405-412
26. Warnecke, C., Willich, T., Holzmeister, J., Bottari, S. P. and Fleck, E. (1999) Efficient transcription of the human angiotensin II type 2 receptor gene requires intronic sequence elements. Biochem. J. 340, 17-24
27. Anderson, W. B., Board, P. G., Gargano, B. and Anders, M. W. (1999) Inactivation of glutathione transferase zeta by dichloroacetic acid and other fluorine-lacking α-haloalkanoic acids. Chem. Res. Toxicol. 12, 1144-1149
28. Tong, Z., Board, P. G. and Anders, M. W. (1998) Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid. Biochem. J. 331, 371-374
29. Tzeng, H.-F., Blackburn, A. C., Boarc, P. G. and Anders, M. W. (2000) Polymorphism- and species-dependent inactivation of glutathione transferase zeta by dichloroacetate. Chem. Res. Toxicol. 13, 231-236
30. Thorn, R., Dixon, D. P., Edwards, R., Cole, D. J. and Lapthorn, A. J. (2001) The structure of a Zeta class glutathione S-transferase from Arabidopsis thaliana: characterisation of a GST with novel active-site architecture and a putative role in tyrosine catabolism. J. Mol. Biol. 308, 949-962
31. Polekhina, G., Board, P. G., Blackburn, A. C. and Parker, M. W. (2001) Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity. Biochemistry 40, 1567-1576
32. Board, P. G., Coggan, M., Chelvanayagam, G., Easteal, S., Jermiin, L. S., Schulte, G. K., Danley, D. E., Hoth, L. R., Griffor, M. C., Kamath, A. V. et al. (2000) Identification, characterization, and crystal structure of the omega class glutathione transferases. J. Biol. Chem. 275, 24798-24806
33. Anders, M. W., Anderson, W. B., Tzeng, H.-F. and Board, P. G. (2001) Glutathione transferase zeta: novel xenobiotic substrates and enzyme inactivation. Chem. Biol. Interact 133, 211-216
34. Board, P., Baker, R. T., Chelvanayagam, G. and Jermiin, L. S. (1997) Zeta, a novel class of glutathione transferases in a range of species from plants to humans. Biochem. J. 328, 929-935
35. Parker, M. W., McKinstry, W. J., Oakley, A. J., Polekhina, G., Rossjohn, J., Chelvanayagam, G., Board, P. G., Di Ilio, C., Caccuri, A. M., Ricci, G. and Lo Bello, M. (2001) Evolution of functional diversity as observed through structural studies of glutathione transferases. Chem. Biol. Interact. 133, 8-12
36. Berhane, K., Widersten, M., Engström, Å., Kozarich, J. W. and Mannervik, B. (1994) Detoxication of base propenals and other α,β-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases. Proc. Natl. Acad. Sci. U.S.A. 91, 1480-1484
37. Ishikawa, T., Esterbauer, H. and Sies, H. (1986) Role of cardiac glutathione transferase and of the glutathione S-conjugate export system in biotransformation of 4-hydroxynonenal in the heart. J. Biol. Chem. 261, 1576-1581
38. Yang, Y. Cheng, J.-Z., Singhal, S. S., Saini, M., Pandya, U., Awasthi, S. and Awasthi, Y. C. (2001) Role of glutathione S-transferases in protection against lipid peroxidation: overexpression of hGSTA2-2 in K562 cells protects against hydrogen peroxide induced apoptosis and inhibits JNK and caspase 3 activation. J. Biol. Chem. 276, 19220-19230