The structure of a zeta class glutathione S-transferase from Arabidopsis thaliana: Characterisation of a GST with novel active-site architecture and a putative role in tyrosine catabolism

Journal of Molecular Biology

Volumn 308, Issue 5, 2001, Pages 949-962

  Thom, Russell ^a   Dixon, David P ^b   Edwards, Robert ^b   Cole, David J ^c   Lapthorn, Adrian J ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b DURHAM UNIVERSITY   (United Kingdom)

^c Aventis Crop Science   (United Kingdom)

Author keywords

Crystal structure; Glutathione S transferase; Malelyacetoacetate isomerase; Zeta class

Indexed keywords

ACETOACETIC ACID DERIVATIVE; GLUTATHIONE TRANSFERASE; ISOMERASE; MALEYLACETOACETATE; TYROSINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARABIDOPSIS; ARTICLE; CATABOLISM; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME STRUCTURE; ISOMERISM; MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

ARABIDOPSIS THALIANA; FUNGI; HEXAPODA; VERTEBRATA;

EID: 0035906701     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4638     Document Type: Article

References (66)

1. Enzymes involved in conversion of tyrosine to acetoacetate
2. Homogentisate metabolism: The isomerisation of maleylacetoacetate by an enzyme which requires glutathione
3. The phenylalanine hydroxylase locus: A marker for the history of phenylketonuria and human genetic diversity
4. Molecular defects in alkaptonuria
5. Tyrosinemia type1b caused by maleylacetoacetate isomerase deficiency: A new enzyme defect
6. Hypertyrosinemia
7. Phenotype characterization of maleylacetoacetate isomerase deficiency in mouse
8. Characterization of a fungal maleylacetoacetate isomerase gene and identification of its human homologue
9. Zeta, a novel class of glutathione transferases in a range of species from plants to humans
10. Theta, a new class of glutathione transferases purified from rat and man
11. Identification, characterization and crystal structure of the omega class glutathione transferases
12. Identification of 3 classes of cytosolic glutathione transferase common to several mammalian-species - Correlation between structural data and enzymatic-properties
13. Glutathione S-transferases - Amino-acid-sequence comparison, classification and phylogenetic relationship
14. Plant glutathione S-transferases: Enzymes with multiple functions in sickness and in health
15. Glutathione S-transferase class kappa: Characterization by the cloning of rat mitochondrial GST and identification of a human homologue
16. Glutathione transferase activities and herbicide selectivity in maize and associated weed species
17. A glutathione S-transferase involved in vacuolar transfer encoded by the maize gene Bronze-2
18. An ethylene-responsive flower senescence-related gene from carnation encodes a protein homologous to glutathione S-transferase
19. Isolation of a zeta class wheat glutathione S-transferase gene
20. Characterisation of a zeta class glutathione transferase from Arabidopsis thaliana with a putative role in tyrosine catabolism
21. Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid
22. Three-dimensional structure of Escherichia coli glutathione S-transferase complexed with glutathione sulfonate: Catalytic roles of Cys10 and His106
23. A mixed disulphide bond in bacterial glutathione transferase: Functional and evolutionary implications
24. Human theta class glutathione transferase: The crystal structure reveals a sulfate-binding pocket within a buried active site
25. X-ray crystal structures of cytosolic glutathione S-transferases. Implications for protein architecture, substrate recognition and catalytic function
26. Structure, catalytic mechanism and evolution of glutathione transferases
27. Mechanistic imperatives for the evolution of glutathione transferases
28. Recruitment of a double bond isomerase to serve as a reductive dehalogenase during biodegradation of pentachlorophenol
29. A program to check the stereochemical quality of protein structures
30. Remarks about protein structure precision
31. Principles of protein-protein interactions
32. Structure and function of glutathione S-transferase
33. Mutagenesis of the active site of the human theta-class glutathione transferase GSTT2-2: Catalysis with different substrates involves different residues
34. Catalytic mechanism and role of hydroxyl residues in the active site of theta class glutathione S-transferases - Investigation of Ser-9 and Tyr-113 in a glutathione S-transferase from the Australian sheep blowfly, Lucilia cuprina
35. Evaluation of possible active site residues in GSTZ 1-1
36. Identification of an N-capping box that affects the α6-helix propensity in glutathione S-transferase superfamily proteins: A role for an invariant aspartic residue
37. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
38. Identification of a novel nutrient-deprivation-induced Sinorhizobium meliloti gene (hmgA) involved in the degradation of tyrosine
39. Characterization of a flavobacterium glutathione S-transferase gene involved in reductive dechlorination
40. Structure determination and refinement of human class glutathione transferase A1-1, and a comparison with the mu and pi class enzymes
41. The three dimensional structure of a glutathione S transferase from the mu gene class. Structural analysis of the binary complex of isoenzyme 3-3 and glutathione at 2.2 Å resolution
42. The three-dimensional structure of class π glutathione transferase from human placenta in complex with glutathione sulfonate at 2.3 Å resolution
43. Three dimensional structure, catalytic properties and evolution of a sigma class glutathione transferase from squid, a progenitor of lens s-crystallins of cephalopods
44. Three dimensional structure of glutathione S-transferase from Arabidopsis thaliana at 2.2 Å resolution: Structural characterization of herbicide-conjugating plant glutathione S-transferase and a novel active site architecture
45. Crystal structure of theta-class glutathione transferase
46. Crystal structures of a schistosomal drug and vaccine target: Glutathione S-transferase from Schistosoma japonica and its complex with the leading antischistosomal drug praziquantel
47. Hierarchical protein structure superposition using both secondary structure and atomic representations
48. Evidence for an essential serine residue in the active site of the theta class glutathione transferase
49. Exploration of the relationship between tetrachlorhydroquinone dehalogenase and the glutathione S-transferase superfamily
50. Identification of a covalent intermediate between glutathione and cysteine 13 formed during catalysis by tetrachlorohydroquinone dehalogenase
51. Purification and properties of maleylacetone cis-trans isomerase from Vibrio 01*
52. Oscillation data reduction program
53. Solvent content of protein crystals
54. The CCP4 suite of programs for protein crystallography
55. Heavy atom location using SHELX-90
56. Maximum likelihood refinement of heavy atom parameters
57. DM, an automated procedure for phase improvement by density modification
58. Cloning, sequencing, crystallisation and X-ray structure of glutathione S-transferase-III from Zea mays var. mutin: A leading enzyme in detoxification of maize herbicides
59. Application of maximum likelihood methods for macromolecular refinement
60. Automated refinement of proteins
61. Efficient anisotropic refinement of macromolecular structures using FFT
62. The Protein Data Bank
63. ESPript: Multiple sequence alignments in PostScript
64. Ribbons
65. Setor: Hardware lighted three dimensional solid model representations of macromolecules
66. SPOCK: Real-time collaborative molecular modelling