In support of Fatty Acid Synthase (FAS) as a metabolic oncogene: Extracellular acidosis acts in an epigenetic fashion activating FAS gene expression in cancer cells

Journal of Cellular Biochemistry

Volumn 94, Issue 1, 2005, Pages 1-4

  Menendez, Javier A ^a,b   Decker, Josiah P ^a   Lupu, Ruth ^a,b  

^a EVANSTON NORTHWESTERN HEALTHCARE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Acidosis; Cancer; Fatty acid synthase; Oncogene; pH; SREBP

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; FAS ANTIGEN; FATTY ACID SYNTHASE; STEROL REGULATORY ELEMENT BINDING PROTEIN;

ACIDOSIS; BINDING SITE; CANCER CELL; CANCER CELL CULTURE; CELL GROWTH; CELL PH; CELL STRAIN MCF 7; CONTROLLED STUDY; EXTRACELLULAR SPACE; GENE ACTIVATION; GENE CONSTRUCT; GENE EXPRESSION; GENE FUNCTION; GENE OVEREXPRESSION; GENETIC EPIGENESIS; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPOXIA; LIPOGENESIS; MOLECULAR MECHANICS; ONCOGENE; ONCOGENE NEU; PH MEASUREMENT; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; REPORTER GENE; SHORT SURVEY; TRANSCRIPTION INITIATION; WILD TYPE; ARTICLE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; TUMOR CELL LINE;

MINK CELL FOCUS-FORMING VIRUS;

ACIDOSIS; CELL LINE, TUMOR; FATTY ACID SYNTHETASE COMPLEX; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; ONCOGENES;

EID: 21644481768     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20310     Document Type: Short Survey

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