Regulation of human osteoclast differentiation by thioredoxin binding protein-2 and redox-sensitive signaling

Journal of Bone and Mineral Research

Volumn 19, Issue 12, 2004, Pages 2057-2064

  Aitken, Cathy J ^a   Hodge, Jason M ^a   Nishinaka, Yumiko ^b   Vaughan, Tanya ^c   Yodoi, Junji ^b   Day, Christopher J ^c   Morrison, Nigel A ^c   Nicholson, Geoffrey C ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c GRIFFITH UNIVERSITY   (Australia)

Author keywords

Activator protein 1; Osteoclast; Redox; Thioredoxin binding protein 2; Thioredoxin 1

Indexed keywords

ACETYLCYSTEINE; ADENOVIRUS VECTOR; ANTIOXIDANT; COLONY STIMULATING FACTOR 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; THIOREDOXIN; TRANSCRIPTION FACTOR AP 1; CARRIER PROTEIN; CD14 ANTIGEN; MEMBRANE PROTEIN; MESSENGER RNA; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TNFRSF11A PROTEIN, HUMAN; TNFSF11 PROTEIN, HUMAN; TXNIP PROTEIN, HUMAN;

ADENOVIRUS; ARTICLE; BINDING AFFINITY; BONE DEVELOPMENT; CELL DIFFERENTIATION; COLONY FORMING UNIT GM; DNA BINDING; GEL MOBILITY SHIFT ASSAY; GENE OVEREXPRESSION; GENE TRANSFER; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MACROPHAGE; OSTEOCLAST; OSTEOLYSIS; OXIDATION REDUCTION REACTION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; BIOSYNTHESIS; CHEMISTRY; CYTOLOGY; DNA MICROARRAY; DOSE RESPONSE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; WESTERN BLOTTING;

ADENOVIRIDAE; ANTIGENS, CD14; ANTIOXIDANTS; BLOTTING, WESTERN; CARRIER PROTEINS; CELL DIFFERENTIATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; HUMANS; MACROPHAGES; MEMBRANE GLYCOPROTEINS; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOCLASTS; OXIDATION-REDUCTION; PROTEIN BINDING; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; THIOREDOXIN; TIME FACTORS; TRANSCRIPTION FACTOR AP-1;

EID: 21644462119     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/JBMR.040913     Document Type: Article

References (51)

1. Droge W 2002 Free radicals in the physiological control of cell function. Physiol Rev 82:47-95.
2. Holmgren A 1989 Thioredoxin and glutaredoxin systems. J Biol Chem 264:13963-13966.
3. Holmgren A 2000 Antioxidant function of thioredoxin and glutaredoxin systems. Antioxid Redox Signal 2:811-820.
4. Haddad JJ 2002 Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors. Cell Signal 14:879-897.
5. Boyle WJ, Simonet WS, Lacey DL 2003 Osteoclast differentiation and activation. Nature 423:337-342.
6. Hall SL, Greendale GA 1998 The relation of dietary vitamin C intake to bone mineral density: Results from the PEPI study. Calcif Tissue Int 63:183-189.
7. Melhus H, Michaelsson K, Holmberg L, Wolk A, Ljunghall S 1999 Smoking, antioxidant vitamins, and the risk of hip fracture. J Bone Miner Res 14:129-135.
8. Leveille SG, LaCroix AZ, Koepsell TD, Beresford SA, Van Belle G, Buchner DM 1997 Dietary vitamin C and bone mineral density in postmenopausal women in Washington State, USA. J Epidemiol Community Health 51:479-485.
9. Wang MC, Luz Villa M, Marcus R, Kelsey JL 1997 Associations of vitamin C, calcium and protein with bone mass in postmenopausal Mexican American women. Osteoporos Int 7:533-538.
10. Morton DJ, Barrett-Connor EL, Schneider DL 2001 Vitamin C supplement use and bone mineral density in postmenopausal women. J Bone Miner Res 16:135-140.
11. Kaptoge S, Welch A, McTaggart A, Mulligan A, Dalzell N, Day NE, Bingham S, Khaw KT, Reeve J 2003 Effects of dietary nutrients and food groups on bone loss from the proximal femur in men and women in the 7th and 8th decades of aae. Osteoporos Int 14:418-428.
12. Maggio D, Barabani M, Pierandrei M, Polidori MC, Catani M, Mecocci P, Senin U, Pacifici R, Cherubini A 2003 Marked decrease in plasma antioxidants in aged osteoporotic women: Results of a cross-sectional study. J Clin Endocrinol Metab 88:1523-1527.
13. Basu S, Michaelsson K, Olofsson H, Johansson S, Melhus H 2001 Association between oxidative stress and bone mineral density. Biochem Biophys Res Commun 288:275-279.
14. Bax BE, Alam AS, Banerji B, Bax CM, Bevis PJ, Stevens CR, Moonga BS, Blake DR, Zaidi M 1992 Stimulation of osteoclastic bone resorption by hydrogen peroxide. Biochem Biophys Res Commun 183:1153-1158.
15. Garrett IR, Boyce BF, Oreffo RO, Bonewald L, Poser J, Mundy GR 1990 Oxygen-derived free radicals stimulate osteoclastic bone resorption in rodent bone in vitro and in vivo. J Clin Invest 85:632-639.
16. Fraser JH, Helfrich MH, Wallace HM, Ralston SH 1996 Hydrogen peroxide, but not superoxide, stimulates bone resorption in mouse calvariae. Bone 19:223-226.
17. Suda N, Morita I, Kuroda T, Murota S 1993 Participation of oxidative stress in the process of osteoclast differentiation. Biochim Biophys Acta 1157:318-323.
18. Steinbeck MJ, Kim JK, Trudeau MJ, Hauschka PV, Karnovsky MJ 1998 Involvement of hydrogen peroxide in the differentiation of clonal HD-11EM cells into osteoclast-like cells. J Cell Physiol 176:574-587.
19. Hall TJ, Schaeublin M, Jeker H, Fuller K, Chambers TJ 1995 The role of reactive oxygen intermediates in osteoclastic bone resorption. Biochem Biophys Res Commun 207:280-287.
20. Rao LG, Krishnadev N, Banasikowska K, Rao AV 2003 Lycopene I - effect on osteoclasts: Lycopene inhibits basal and parathyroid hormone-stimulated osteoclast formation and mineral resorption mediated by reactive oxygen species in rat bone marrow cultures. J Med Food 6:69-78.
21. Mody N, Parhami F, Sarafian TA, Demer LL 2001 Oxidative stress modulates osteoblastic differentiation of vascular and bone cells. Free Radic Biol Med 31:509-519.
22. Ramamurthy NS, Vernillo AT, Greenwald RA, Lee HM, Sorsa T, Golub LM, Rifkin BR 1993 Reactive oxygen species activate and tetracyclines inhibit rat osteoblast collagenase. J Bone Miner Res 8:1247-1253.
23. Kikuyama A, Fukuda K, Mori S, Okada M, Yamaguchi H, Hamanishi C 2002 Hydrogen peroxide induces apoptosis of osteocytes: Involvement of calcium ion and caspase activity. Calcif Tissue Int 71:243-248.
24. Lean JM, Davies JT, Fuller K, Jagger CJ, Kirstein B, Partington GA, Urry ZL, Chambers TJ 2003 A crucial role for thiol antioxidants in estrogen-deficiency bone loss. J Clin Invest 112:915-923.
25. Hodge JM, Kirkland MA, Aitken CJ, Waugh C, Myers DE, Lopez CM, Adams B, Nicholson GC 2004 Osteoclastic potential of human CFU-GM: Biphasic effect of GM-CSF. J Bone Miner Res 19:190-199.
26. Nishiyama A, Matsui M, Iwata S, Hirota K, Masutani H, Nakamura H, Takagi Y, Sono H, Gon Y, Yodoi J 1999 Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression. J Biol Chem 274:21645-21650.
27. Yamanaka H, Maehira F, Oshiro M, Asato T, Yanagawa Y, Takei H, Nakashima Y 2000 A possible interaction of thioredoxin with VDUP1 in HeLa cells detected in a yeast two-hybrid system. Biochem Biophys Res Commun 271:796-800.
28. Nishiyama A, Masutani H, Nakamura H, Nishinaka Y, Yodoi J 2001 Redox regulation by thioredoxin and thioredoxin-binding proteins. IUBMB Life 52:29-33.
29. Junn E, Han SH, Im JY, Yang Y, Cho EW, Um HD, Kim DK, Lee KW, Han PL, Rhee SG, Choi I 2000 Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function. J Immunol 164:6287-6295.
30. Matsui M, Oshima M, Oshima H, Takaku K, Maruyama T, Yodoi J, Taketo MM 1996 Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene. Dev Biol 178:179-185.
31. Nishinaka Y, Nishiyama A, Matsutani H, Oka S, Absan K, Nakayama Y, Yasuyuki I, Nakamura H, Maeda M, Yodoi J 2004 Loss of thioredoxin-binding protein-2/vitamin D3 up-regulated protein 1 in human T-cell leukemia virus type 1-dependent T-cell transformation: Implications for adult T-cell leukemia leukemogenesis. Cancer Res 64:1287-1292.
32. Nicholson GC, Malakellis M, Collier FM, Cameron PU, Holloway WR, Gough TJ, Gregorio-King C, Kirkland MA, Myers DE 2000 Induction of osteoclasts from CD14-positive human peripheral blood mononuclear cells by receptor activator of nuclear factor kappaB ligand (RANKL). Clin Sci (Lond) 99:133-140.
33. Mustacich D, Powis G 2000 Thioredoxin reductase. Biochem J 346:1-8.
34. Zhao R, Masayasu H, Holmgren A 2002 Ebselen: A substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant. Proc Natl Acad Sci USA 99:8579-8584.
35. Chen KS, DeLuca HF 1994 Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3. Biochim Biophys Acta 1219:26-32.
36. Shalev A, Pise-Masison CA, Radonovich M, Hoffmann SC, Hirshberg B, Brady JN, Harlan DM 2002 Oligonucleotide microarray analysis of intact human pancreatic islets: Identification of glucose-responsive genes and a highly regulated TGFbeta signaling pathway. Endocrinology 143:3695-3698.
37. Bodnar JS, Chatterjee A, Castellani LW, Ross DA, Ohmen J, Cavalcoli J, Wu C, Dains KM, Catanese J, Chu M, Sheth SS, Charugundla K, Demant P, West DB, de Jong P, Lusis AJ 2002 Positional cloning of the combined hyperlipidemia gene Hyplip1. Nat Genet 30:110-116.
38. Schulze PC, De Keulenaer GW, Yoshioka J, Kassik KA, Lee RT 2002 Vitamin D3-upregulated protein-1 (VDUP-1) regulates redox-dependent vascular smooth muscle cell proliferation through interaction with thioredoxin. Circ Res 91:689-695.
39. Young LH, Yang X, Voigt JM 1996 Alteration of gene expression in rat mammary tumors induced by N-methyl-N-nitrosourea. Mol Carcinog 15:251-260.
40. Ikarashi M, Takahashi Y, Ishii Y, Nagata T, Asai S, Ishikawa K 2002 Vitamin D3 up-regulated protein 1 (VDUP1) expression in gastrointestinal cancer and its relation to stage of disease. Anticancer Res 22:4045-4048.
41. Lincoln DT, Ali Emadi EM, Tonissen KF, Clarke FM 2003 The thioredoxin-thioredoxin reductase system: Over-expression in human cancer. Anticancer Res 23:2425-2433.
42. Nakamura H, Nakamura K, Yodoi J 1997 Redox regulation of cellular activation. Annu Rev Immunol 15:351-369.
43. Hirota K, Murata M, Sachi Y, Nakamura H, Takeuchi J, Mori K, Yodoi J 1999 Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-kappaB. J Biol Chem 274:27891-27897.
44. Nishinaka Y, Masutani H, Nakamura H, Yodoi J 2001 Regulatory roles of thioredoxin in oxidative stress-induced cellular responses. Redox Rep 6:289-295.
45. Watson WH, Jones DP 2003 Oxidation of nuclear thioredoxin during oxidative stress. FEBS Lett 543:144-147.
46. Wang Y, De Keulenaer GW, Lee RT 2002 Vitamin D(3)-up-regulated protein-1 is a stress-responsive gene that regulates cardiomyocyte viability through interaction with thioredoxin. J Biol Chem 277:26496-2500.
47. Gius D, Botero A, Shah S, Curry HA 1999 Intracellular oxidation/reduction status in the regulation of transcription factors NF-kappaB and AP-1. Toxicol Lett 106:93-106.
48. Flohe L, Brigelius-Flohe R, Saliou C, Traber MG, Packer L 1997 Redox regulation of NF-kappa B activation. Free Radic Biol Med 22:1115-1126.
49. Armstrong JS, Steinauer KK, Hornung B, Irish JM, Lecane P, Birrell GW, Peehl DM, Knox SJ 2002 Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line. Cell Death Differ 9:252-263.
50. Kinscherf R, Fischbach T, Mihm S, Roth S, Hohenhaus-Sievert E, Weiss C, Edler L, Bartsch P, Droge W 1994 Effect of glutathione depletion and oral N-acetyl-cysteine treatment on CD4+ and CD8+ cells. FASEB J 8:448-451.
51. Beckman KB, Ames BN 1998 The free radical theory of aging matures. Physiol Rev 78:547-581.