Regulation of lck degradation and refractory state in CD8+ cytotoxic T lymphocytes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 26, 2005, Pages 9264-9269

  Uhlin, Michael ^a   Masucci, Maria G ^a   Levitsky, Victor ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Activation; Kinase

Indexed keywords

ALPHA INTERFERON; CD3 ANTIGEN; CD3 ANTIGEN ZETA CHAIN; CD8 ANTIGEN; CYSTEINE PROTEINASE INHIBITOR; INTERLEUKIN 1; INTERLEUKIN 15; LYMPHOKINE; PROTEASOME; PROTEIN KINASE LCK; PROTEIN KINASE ZAP 70; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ACTIVATION INDUCED NONRESPONSIVENESS; ARTICLE; CYTOTOXIC T LYMPHOCYTE; EXPRESSION VECTOR; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE ACTIVATION; LYSOSOME; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

ANTIGENS, CD3; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; CELL SEPARATION; CLONING, MOLECULAR; DOWN-REGULATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOSOMES; FLOW CYTOMETRY; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOBLOTTING; INTERFERON TYPE II; INTERFERON-ALPHA; INTERLEUKIN-15; INTERLEUKIN-2; KINETICS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); LYMPHOKINES; LYSOSOMES; PEPTIDE HYDROLASES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN-TYROSINE KINASES; T-LYMPHOCYTES; T-LYMPHOCYTES, CYTOTOXIC; TIME FACTORS; TRANSFECTION; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 21544471802     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0406333102     Document Type: Article

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