Magnolol induces the distributional changes of p160 and adipose differentiation-related protein in adrenal cells

Histochemistry and Cell Biology

Volumn 123, Issue 4-5, 2005, Pages 429-439

  Chien, Chung Liang ^a   Chen, Yung Chia ^a   Chang, Ming Fong ^a   Greenberg, Andrew S ^b   Wang, Seu Mei ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TUFTS UNIVERSITY   (United States)

Author keywords

Adipose differentiation related protein; Adrenal cells; Magnolol; p160

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ADIPOPHILIN; FAT DROPLET; MAGNOLOL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN P160; THREONINE;

ADRENAL CELL; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FREE SYSTEM; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; FEMALE; IMMUNOHISTOCHEMISTRY; LIPID ANALYSIS; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SURFACE PROPERTY;

ADRENAL GLANDS; ANIMALS; BIPHENYL COMPOUNDS; BLOTTING, WESTERN; BUTADIENES; CELLS, CULTURED; CYTOPLASMIC GRANULES; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; FLAVONOIDS; FLUORESCENT ANTIBODY TECHNIQUE; HISTONE ACETYLTRANSFERASES; LIGNANS; LIPID METABOLISM; MEMBRANE PROTEINS; MICROSCOPY, FLUORESCENCE; NITRILES; OXAZOLES; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN TRANSPORT; PYRANS; RATS; RATS, WISTAR; SPIRO COMPOUNDS; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 21544464305     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-005-0771-8     Document Type: Article

References (46)

1. Abraham ST, Benscoter HA, Schworer CM, Singer HA (1997) A role of Ca2+/calmodulin-dependent protein kinase II in the mitogen-activated protein kinase signaling cascade of cultured rat aortic vascular smooth muscle cells. Cir Res 81:575-584
2. Brasaemle DL, Barber T, Wolins NE, Serrero G, Blanchette-Mackie EJ, Londos C (1997) Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein. J Lipid Res 38:2249-2262
3. Brasaemle DL, Rubin B, Harten IA, Gruia-Gray J, Kimmel AR, Londos C (2000) Perilipin A increases triacylglycerol stirage by decreasing the rate of triacylglycerol hydrolysis. J Biol Chem 275:38486-38493
4. Buechler C, Ritter M, Duong CQ, Orso E, Kapinsky M, Schimitz G (2001) Adipophilin is a sensitive marker for lipid loading in human blood monocytes. Biochim Biophys Acta 1532:97-104
5. Chang L, Karin M (2001) Mammalian MAP kinase signaling cascades. Nature 410:37-40
6. Chen YH, Lin SJ, Chen JW, Ku HH, Chen YL (2002) Magnolol attenuates VCAM-I expression in vitro in TNF-α-treated human aortic endothelial cells and in vivo in the aorta of cholesterol-fed rabbits. British J Pharmacol 135:37-37
7. Cherradi N, Pardo B, Greenberg AS, Kraemer FB, Capponi AM (2003) Angiotensin II activates cholesterol ester hydrolase in bovine adrenal glomerulosa cells through phosphorylation mediated by p42/p44 mitogen-activated protein kinase. Endocrinology 144:4905-4915
8. Clifford GM, Damion KT McCormick, Constantine L, Vernon RG, Yeaman SJ (1998) Dephosphorylation of perilipin by protein phosphatase present in rat adipocytes. FEBS Lett 435:125-129
9. Clifford GM, Londos C, Kraemer FB, Vernon RG, Yeaman SJ (2000) Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation of rat adipocytes. J Biol Chem 275:5011-5015
10. Cook KG, Yeaman SJ (1982) Direct evidence that cholesterol ester hydrolase from adrenal cortex is the same enzyme as hormone-sensitive lipase from adipose tissue. Eur J Biochem 125:245-249
11. Cox ME, Ely CM, Catling AD, Weber MJ, Parsons SJ (1996) Tyrosine kinases are required for catecholamine secretion and mitogen-activated protein kinase activation in bovine adrenal chromaffin cells. J Neurochem 66:1103-1112
12. Fong TH, Wang SM (1997) Dissection of the signaling mechanism for capsule detachment of lipid droplets in rat adrenocortical cells. J Cell Biochem 65:67-74
13. Fong TH, Yang CC, Greenberg AS, Wang SM (2002) Immunocytochemical studies on lipid droplet-surface proteins in adrenal cells. J Cell Biochem 86:432-439
14. Fritz JD, Swart DR, Greaser ML (1989) Factors affecting polyacrylamide gel electrophoresis and electroblotting of high molecular-weight myofibrillar protein. Anal Biochem 180:205-210
15. Frolov A, Petrescu A, Atshaves BP, So PTC, Gratton E, Serrero G, Schroeder F (2000) High density lipoprotein-mediated cholesterol uptake and targeting to lipid droplets in intact L-cell fibroblasts. A single and multiphoton fluorescence approach. J Biol Chem 275:12769-12780
16. Gao J, Ye H, Serrero G (2000) Stimulation of adipose differentiation related protein (ADRP) expression in adipocyte precursors by long chain fatty acids. J Cell Physiol 182:297-302
17. Greenberg AS, Egan JJ, Wek SA, Garty NB, Balanchette MEJ, Londos C (1991) Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets. J Biol Chem 266:11341-11346
18. Greenberg AS, Shen WJ, Muliro K, Patel S, Souza SC, Roth RA, Kraemer FB (2001) Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway. J Biol Chem 276:45456-45461
19. Gyles SL, Burns CJ, Persaud SJ, Jones PM, Whitehouse BJ (2000) A role for the p42/44 isoforms of MAPK in the regulation of steroid secretion from Y-1 mouse adrenocortical cells. Endocrine Res 26:579-581
20. Heid HW, Schnölzer M, Keenan TW (1996) Adipocyte differentiation-related protein is secreted into milk as a constitute of milk lipid globule membrane. Biochem J 320:1025-1030
21. Hodgkinson CP, Ye S (2003) Microarray analysis of peroxisome proliferator-activated receptor γ-induced changes in gene expression in macrophages. Biochem Biophys Res Commun 308:505-510
22. Huang SH, Shen WJ, Yeo HL, Wang SM (2004) Signaling pathway of magnolol-stimulated lipolysis in sterol ester-loaded 3T3-L1 preadipocytes. J Cell Biochem 91:1021-1029
23. Imamura M, Inoguchi T, Ikuyama S, Taniguchi S, Kobayashi K, Nakashima N, Nawata H (2002) ADRP stimulates lipid accumulation and lipid droplet formation in murine fibroblasts. Am J Endocrinol Metab 283:775-783
24. Jiang HP, Serrero G (1992) Isolation and characterization of a full-length cDNA coding for an adipose differentiation-related protein. Proc Natl Acad Sci USA 89: 7856-7860
25. Kraemer FB, Shen W, Natu V, Patel S, Osuga JI, Ishibashi S, Azhar S (2002) Adrenal neutral cholesteryl ester hydrolase : identification, subcellular distributions, and sex differences. Endocrinology 143:801-806
26. Lin SY, Liu JD, Chang HC, Yeh SD, Lin CH, Lee WS (2002) Magnolol suppresses proliferation of cultured human colon and liver cancer cells by inhibiting DNA synthesis and activating apoptosis. J Cell Biochem 84:532-544
27. Liu PC, Huber R, Stow MD, Schlingmann KL, Collier P, Liao B, Link J, Burn TC, Hollis G, Young PR, Mukherjee R (2003) Induction of endogenous genes by peroxisome proliferator activated receptor alpha ligands in a human kidney cell line and in vivo. J Steroid Biochem Mol Biol 85:71-79
28. Londos C, Gruia-Gray J, Brasaemle DL, Rondinone CM, Takeda T, Dwyer NK, Barber T, Kimmel AR, Blanchette-Mackie EJ (1996) Perilipin: possible roles in structure and metabolism of intracellular neutral lipids in adipocytes and steroidogenic cells. Int J Obesity Related Metabolic Disorder 3:S97-S101
29. Londos C, Brasaemle DL, Schultz CJ, Segrest JP, Kimmel AR (1999) Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells. Sem Cell Dev Biol 10:51-58
30. Londos C, Brasaemle DL, Gruia-Gray J, Servetnick DA, Schultz CJ, Levin DM, Kimmel AR (1995)Perilipin: unique proteins associated with intracellular neutral lipid droplets in adipocytes and steroidogenic cells. Biochem Soc Transact 23:11-15
31. Nakamura N, Fujimoto T (2003) Adipose differentiation-related protein has two independent domains for targeting to lipid droplets. Biochem Biophys Res Commun 27:306-338
32. Seger R, Krebs EG (1995) The MAPK signaling cascade. FASEB J 9:726-735
33. Serrero G, Frolov A, Schroeder F, Tanaka K, Gelhaar L (2000) Adipose differentiation related protein: expression, purification of recombinant protein in Escherichia coli and characterization of its fatty acid binding properties. Biochim Biophy Acta 1488:245-254
34. Servetnick SA, Brasaemle DL, Gruia-Gray J, Kimmel AR, Wolff J, Londos C (1995) Perilipins are associated with cholesterol ester droplets in steroidogenic adrenal cortical and Leydig cells. J Biol Chem 270:16970-16973
35. Souza SC, de Vargas LM, Yamamoto MT, Lien P, Franciosa MD, Moss LG, Greenberg AS (1998) Overexpression of perilipin A and B blocks the ability of tumor necrotic factor alpha to increase lipolysis in 3T3-L1 adipocytes. J Biol Chem 273: 24665-24669
36. Steiner S, Wahl D, Mangold BL, Robison R, Raymackers J, Meheus L, Anderson NL, Cordier A (1996) Induction of the adipose differentiation-related protein in liver of etomoxir-treated rats. Biochem Biophys Res Commun 218:777-782
37. Sztalryd C, Guoheng Xu, Dorward H, Tansey JT, Contreas JA, Kimmel AR, Londos C (2003) Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation. J Cell Biol 161:1093-1103
38. Tansey JT, Huml AM, Vogt KE, Davis JM, Jones KA, Fraser DL, Brasaemle AR, Londos C (2003) Functional studies on native and mutated forms of perilipins. A role in protein kinase A-mediated lipolysis of triacylglycerols. J Biol Chem 278: 8401-8406
39. Tian Y, Smith RD, Balla T, Catt KJ (1998) Angiotensin II activates mitogen-activated protein kinase via protein kinase C and Ras/Raf-1 kinase in bovine adrenal glomerulosa cells. Endocrinology 139:1801-1809
40. ++ -channel blockade by magnolol, an antiplatelet agent isolated from Chinese herb Magnolia officinalis, in rat thoracic aorta. Life Sci 47:1153-1161
41. Van Biesen T, Luttrell LM, Hawes BE, Lefkowitz RJ (1996) Mitogenic signaling via G protein-coupled receptors. Endocrine Rev 17:698-714
42. Wang SM, Fong TH (1995) A lipid droplet-specific capsule is present in rat adrenal cells: evidence from a monoclonal anti-body. Biochem Biophys Res Commun 217:81-88
43. Wang SM, Lee LJ, Huang YT, Chen JJ, Chen YL (2000) Magnolol stimulates steroidogenesis in rat adrenal cells. Br J Pharmacol 131: 1172-1178
44. Wang SM, Hwang RD, Greenberg AS, Yeo HL (2003) Temporal and spatial assembly of lipid droplet-associated proteins in 3T3-L1 preadipocytes. Histochem Cell Biol 120:285-292
45. Yang SE, Hsieh MT, Tsai TH, Hsu SL (2003) Effector mechanism of magnolol-induced apoptosis in human lung squamous carcinoma CH27 cells. Br J Pharmacol 138:193-201
46. Zhong WB, Wang CY, Ho KJ, Lu FJ, Chang TC, Lee WS (2003) Magnolol induces apoptosis in human leukemia cells via cytochrome c release and caspase activation. Anticancer drugs 14:211-217