Rat cerebellar granule cells are protected from glutamate-induced excitotoxicity by S-nitrosoglutathione but not glutathione

American Journal of Physiology - Cell Physiology

Volumn 286, Issue 4 55-4, 2004, Pages

  Li, Chung Yu ^a   Chin, Ting Yu ^a   Chueh, Sheau Huei ^a  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

Cytosolic calcium concentration; N methyl D aspartate; Reactive oxygen species

Indexed keywords

CASPASE 3; GLUTAMIC ACID; GLUTATHIONE; N ACETYL S NITROSOPENICILLAMINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE; NITRIC OXIDE DONOR; REACTIVE OXYGEN METABOLITE; S NITROSOGLUTATHIONE; AMINO ACID RECEPTOR BLOCKING AGENT; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; ENZYME INHIBITOR; GLYCINE; IONOPHORE; MAGNESIUM; NEUROPROTECTIVE AGENT; NEUROTOXIN; THAPSIGARGIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; EXTRACELLULAR CALCIUM; GLIA CELL; GRANULE CELL; IMMUNOCYTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CELL CULTURE; CEREBELLUM; CYTOLOGY; DRUG EFFECT; METABOLISM; NERVE CELL; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALIA;

ANIMALS; CARBONYL CYANIDE M-CHLOROPHENYL HYDRAZONE; CELLS, CULTURED; CEREBELLUM; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; GLUTATHIONE; GLYCINE; IONOPHORES; MAGNESIUM; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXINS; NITRIC OXIDE; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTORS, N-METHYL-D-ASPARTATE; S-NITROSOGLUTATHIONE; THAPSIGARGIN;

EID: 2142820816     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00127.2003     Document Type: Article

References (47)

1. Broillet MC and Firestein S. Direct activation of the olfactory cyclic nucleotide-gated channel through modification of sulfhydryl groups by NO compounds. Neuron 16: 377-385, 1996.
2. 2+ channel. Neuron 18: 951-958, 1997.
3. Campbell DL, Stamler JS, and Strauss HC. Redox modulation of L-type calcium channels in ferret ventricular myocytes. Dual mechanism regulation by nitric oxide and S-nitrosothiols. J Gen Physiol 108: 277-293, 1996.
4. Castilho RF, Hansson O, Ward MW, Budd SL, and Nicholls DG. Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells. J Neurosci 18: 10277-10286, 1998.
5. Cathcart R, Schwiers E, and Ames BN. Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay. Anal Biochem 134: 111-116, 1983.
6. 2+ fluxes and neurotoxicity in rat cerebellar granule cells. Brain Res 779: 194-204, 1998.
7. Chin TY, Hwang HM, and Chueh SIL Distinct effects of different calcium-mobilizing agents on cell death in NG108-15 neuroblastoma × glioma cells. Mol Pharmacol 61: 486-494, 2002.
8. Choi DW. Ionic dependence of glutamate neurotoxicity. J Neurosci 7: 369-379, 1987.
9. Choi DW. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1: 623-634, 1988.
10. 2+ increase by bradykinin or ATP in NG108-15 cells. J Biol Chem 270: 16630-16637, 1995.
11. Coyle JT and Puttfarcken P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 262: 689-695, 1993.
12. Cunningham AJ and Szenberg A. Further improvements in the plaque technique for detecting single antibody-forming cells. Immunology 14: 599-601, 1968.
13. Dawson VL, Dawson TM, London ED, Bredt DS, and Snyder SH. Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proc Natl Acad Sci USA 88: 6368-6371, 1991.
14. + deprivation. J Neurochem 70: 1809-1818, 1998.
15. Dugan LL, Sensi SL, Canzoniero LMT, Handran SD, Rothman SM, Lin TS, Goldberg MP, and Choi DW. Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate. J Neurosci 15: 6377-6388, 1995.
16. Faulkner KM, Liochev SI, and Fridovich I. Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo. J Biol Chem 269: 23471-23476, 1994.
17. Frandsen A and Schousboe A. Excitatory amino acid-mediated excitotoxicity and calcium homeostasis in cultured neurons. J Neurochem 60: 1202-1211, 1993.
18. Gallo V, Ciotti MT, Coletti A, Aloisi F, and Livi G. Selective release of glutamate from cerebellar granule cells differentiating in culture. Proc Natl Acad Sci USA 79: 7919-7923, 1982.
19. Gallo V, Kingsbury A, Balazs R, and Jorgensen OS. The role of depolarization in the survival and differentiation of cerebellar granule cells in culture. J Neurosci 7: 2203-2213, 1987.
20. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260: 3440-3450, 1985.
21. Johnson JW and Ascher P. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 325: 529-531, 1987.
22. 2+ overload induced by endogenous excitatory amino acids following a glutamate pulse. FEBS Lett 393: 135-138, 1996.
23. 2+ uptake by mitochondrial inhibitors amplifies the glutamate-induced calcium response in cultured cerebellar granule cells. FEBS Lett 458: 162-166, 1999.
24. Koh JY and Choi DW. Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay. J Neurosci Methods 20: 83-90, 1987.
25. Krainock R and Murphy S. Heregulin upregulates the expression of nitric oxide synthase (NOS)-1 in rat cerebellar granule neurons via the ErbB4 receptor. J Neurochem 76: 312-315, 2001.
26. Lafon-Cazal M, Pietri S, Culcasi M, and Bockaert J. NMDA-dependent superoxide production and neurotoxicity. Nature 364: 535-537, 1993.
27. Lei SZ, Pan ZH, Aggarwal SK, Chen HS, Hartman J, Sucher NJ, and Lipton SA. Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex. Neuron 8: 1087-1099, 1992.
28. Leslie SW, Brown LM, Trent RD, Lee YH, Morris JL, Jones TW, Randall PK, Lau SS, and Monks TJ. Stimulation of N-methyl-D-aspartate receptor-mediated calcium entry into dissociated neurons by reduced and oxidized glutathione. Mol Pharmacol 41: 308-314, 1992.
29. Levi G, Aloisi F, Ciotti MT, and Gallo V. Autoradiographic localization and depolarization-induced release of acidic amino acids in differentiating cerebellar granule cell cultures. Brain Res 290: 77-86, 1984.
30. Lipton SA, Choi YB, Pan ZH, Lei SZ, Chen HSV, Sucher NJ, Loscalzo J, Singel DJ, and Stamler JS. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitrosocompounds. Nature 364: 626-632, 1993.
31. 2+ influx underlies potent induction of injury. J Neurosci 16: 5457-5465, 1996.
32. 2+ of NMDA responses in spinal cord neurons. Nature 309: 261-263, 1984.
33. Mori H and Mishina M. Structure and function of the NMDA receptor channel. Neuropharmacology 34: 1219-1237, 1995.
34. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63, 1983.
35. 2+ signals in cerebellar granule neurons in culture. J Neurosci 19: 8765-8777, 1999.
36. Nicholls DG and Budd SL. Mitochondria and neuronal glutamate excitotoxicity. Biochim Biophys Acta 1366: 97-112, 1998.
37. Nowak L, Bregestovski P, Ascher P, Herbet A, and Prochiantz A. Magnesium gates glutamate-activated channels in mouse central neurons. Nature 307: 462-465, 1984.
38. Ogita K, Enomoto R, Nakahara F, Ishitsubo N, and Yoneda Y. A possible role of glutathione as an endogenous agonist at the N-methyl-D-aspartate recognition domain in rat brain. J Neurochem 64: 1088-1096, 1995.
39. Peng TI and Greenamyre T. Privileged access to mitochondria of calcium influx through N-methyl-D-aspartate receptors. Mol Pharmacol 53: 974-980, 1998.
40. Reynolds LJ and Hastings TG. Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J Neurosci 15: 3318-3327, 1995.
41. Stamier JS, and Singel DJ, and Loscalzo J. Biochemistry of nitric oxide and its redox-activated forms. Science 258: 1898-1902, 1992.
42. Tenneti L, D'Emilia DM, Troy CM, and Lipton SA. Role of caspases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons. J Neurochem 71: 946-959, 1998.
43. Tymianski M, Charlton MP, Carlen PL, and Tator CH. Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons. J Neurosci 13: 2085-2104, 1993.
44. 2+ loads by mitochondria in cultured rat hippocampal neurons. J Neurophysiol 76: 1611-1621, 1996.
45. 2+ following intense glutamate stimulation of cultured rat forebrain neurons. J Physiol 498: 31-47, 1997.
46. Xu L, Eu JP, Meissner G, and Stamler JS. Activation of the cardiac calcium release channel (ryanodine receptor) by poly-S-nitrosylation. Science 279: 234-237, 1998.
47. Yan GM, Ni B, Weller M, Wood K, and Paul SM. Depolarization or glutamate receptor activation blocks apoptotic cell death of cultured cerebellar granule neurons. Brain Res 656: 43-52, 1994.