Human interleukin-19 and its receptor: A potential role in the induction of Th2 responses

International Immunopharmacology

Volumn 4, Issue 5, 2004, Pages 615-626

  Gallagher, Grant ^a   Eskdale, Joyce ^a   Jordan, William ^a   Peat, Jon ^b   Campbell, John ^b   Boniotto, Michele ^a   Lennon, Greig P ^a   Dickensheets, Harold ^c   Donnelly, Raymond P ^c  

^a UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

Induction; Interleukin 19; Th2 response

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 19; INTERLEUKIN 19 RECEPTOR; INTERLEUKIN RECEPTOR; LIPOPOLYSACCHARIDE; UNCLASSIFIED DRUG;

CELL MATURATION; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; DOWN REGULATION; HUMAN; MONOCYTE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE; TH1 CELL; TH2 CELL; UPREGULATION;

HUMANS; INTERLEUKIN-10; INTERLEUKINS; LEUKOCYTES, MONONUCLEAR; RECEPTORS, INTERLEUKIN; TH2 CELLS;

EID: 2142760057     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2004.01.005     Document Type: Review

References (64)

1. Mosmann T.R., Coffman R.L. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:1989;145-173
2. Mosmann T.R., Cherwinski H., Bond M.W., Giedlin M.A., Coffman R.L. Two types of murine helper T cell clone: I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136(7):1986 (Apr. 1);2348-2357
3. Seder R.A., Paul W.E. Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annu. Rev. Immunol. 12:1994;635-673
4. Groux H., O'Garra A., Bigler M., Rouleau M., Antonenko S., de Vries J.E., et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature. 389(6652):1997 (Oct. 16);737-742
5. Roncarolo M.G., Bacchetta R., Bordignon C., Narula S., Levings M.K. Type 1 T regulatory cells. Immunol. Rev. 182:2001 (Aug.);68-79
6. Kemper C., Chan A.C., Green J.M., Brett K.A., Murphy K.M., Atkinson J.P. Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature. 421(6921):2003 (Jan. 23);388-392
7. Levings M.K., Sangregorio R., Sartirana C., Moschin A.L., Battaglia M., Orban P.C., et al. Human CD25+ CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells. J. Exp. Med. 196(10):2002 (Nov. 18);1335-1346
8. Levings M.K., Bacchetta R., Schulz U., Roncarolo M.G. The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells. Int. Arch. Allergy Immunol. 129(4):2002 (Dec.);263-276
9. Street N.E., Schumacher J.H., Fong T.A., Bass H., Fiorentino D.F., Leverah J.A., et al. Heterogeneity of mouse helper T cells. Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells. J. Immunol. 144(5):1990 (Mar. 1);1629-1639
10. Swain S.L., Weinberg A.D., English M., Huston G. IL-4 directs the development of Th2-like helper effectors. J. Immunol. 145(11):1990 (Dec. 1);3796-3806
11. Hsieh C.S., Macatonia S.E., Tripp C.S., Wolf S.F., O'Garra A., Murphy K.M. Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science. 260(5107):1993 (Apr. 23);547-549
12. Kaplan M.H., Sun Y.L., Hoey T., Grusby M.J. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature. 382(6587):1996 (Jul. 11);174-177
13. Coccia E.M., Passini N., Battistini A., Pini C., Sinigaglia F., Rogge L. Interleukin-12 induces expression of interferon regulatory factor-1 via signal transducer and activator of transcription-4 in human T helper type 1 cells. J. Biol. Chem. 274(10):1999 (Mar. 5);6698-6703
14. Szabo S.J., Kim S.T., Costa G.L., Zhang X., Fathman C.G., Glimcher L.H. A novel transcription factor. T-bet, directs Th1 lineage commitment. Cell. 100(6):2000 (Mar. 17);655-669
15. Takeda K., Tanaka T., Shi W., Matsumoto M., Minami M., Kashiwamura S., et al. Essential role of Stat6 in IL-4 signalling. Nature. 380(6575):1996 (Apr. 18);627-630
16. Ho I.C., Hodge M.R., Rooney J.W., Glimcher L.H. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell. 85(7):1996 (Jun. 28);973-983
17. Zheng W., Flavell R.A. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell. 89(4):1997 (May 16);587-596
18. Rogge L., Bianchi E., Biffi M., Bono E., Chang S.Y., Alexander H., et al. Transcript imaging of the development of human T helper cells using oligonucleotide arrays. Nat. Genet. 25(1):2000 (May);96-101
19. Chtanova T., Kemp R.A., Sutherland A.P., Ronchese F., Mackay C.R. Gene microarrays reveal extensive differential gene expression in both CD4(+) and CD8(+) type 1 and type 2 T-cells. J. Immunol. 167:2001;3057-3063
20. Granucci F., Castagnoli P.R., Rogge L., Sinigaglia F. Gene expression profiling in immune cells using microarray. Int. Arch. Allergy Immunol. 126(4):2001 (Dec.);257-266
21. Hamalainen H., Zhou H., Chou W., Hashizume H., Heller R., Lahesmaa R. Distinct gene expression profiles of human type 1 and type 2 T helper cells. Genome Biol. 2(7):2001;. [RESEARCH0022]
22. Nedospasov S.A., Hirt B., Shakhov A.N., Dobrynin V.N., Kawashima E., Accolla R.S., et al. The genes for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) are tandemly arranged on chromosome 17 of the mouse. Nucleic Acids Res. 14(19):1986 (Oct. 10);7713-7725
23. Li H., Chen J., Huang A., Stinson J., Heldens S., Foster J., et al. Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family. Proc. Natl. Acad. Sci. U. S. A. 97(2):2000 (Jan. 18);773-778
24. Aggarwal S., Gurney A.L. IL-17: prototype member of an emerging cytokine family. J. Leukoc. Biol. 71(1):2000 (Jan.);1-8
25. Blumberg H., Conklin D., Xu W.F., Grossmann A., Brender T., Carollo S., et al. Interleukin 20: discovery, receptor identification, and role in epidermal function. Cell. 104(1):2001 (Jan. 12);9-19
26. Dumoutier L., Louahed J., Renauld J.C. Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9. J. Immunol. 164(4):2000 (Feb. 15);1814-1819
27. Jiang H., Lin J.J., Su Z.Z., Goldstein N.I., Fisher P.B. Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression. Oncogene. 11(12):1995 (Dec. 21);2477-2486
28. Knappe A., Hor S., Wittmann S., Fickenscher H. Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiri. J. Virol. 74(8):2000 (Apr.);3881-3887
29. Dumoutier L., Van Roost E., Ameye G., Michaux L., Renauld J.C. IL-TIF/IL-22: genomic organization and mapping of the human and mouse genes. Genes Immun. 1(8):2000 (Dec.);488-494
30. Gallagher G., Dickensheets H., Eskdale J., Izotova L.S., Mirochnitchenko O.V., Peat J.D., et al. Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10). Genes Immun. 1(7):2000 (Oct.);442-450
31. Chang C., Magracheva E., Kozlov S., Fong S., Tobin G., Kotenko S., et al. Crystal structure of interleukin-19 defines a new subfamily of helical cytokines. J. Biol. Chem. 278(5):2003 (Jan. 31);3308-3313
32. Dumoutier L., Leemans C., Lejeune D., Kotenko S.V., Renauld J.C. STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types. J. Immunol. 167(7):2001 (Oct. 1);3545-3549
33. Wang M., Tan Z., Zhang R., Kotenko S.V., Liang P. Interleukin 24 (MDA-7/MOB-5) signals through two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2. J. Biol. Chem. 277(9):2001 (Mar. 1);7341-7347
34. Parrish-Novak J., Xu W., Brender T., Yao L., Jones C., West J., et al. Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions. J. Biol. Chem. 277(49):2002 (Dec. 6);47517-47523
35. Fickenscher H., Hor S., Kupers H., Knappe A., Wittmann S., Sticht H. The interleukin-10 family of cytokines. Trends Immunol. 23(2):2002 (Feb.);89-96
36. Kotenko S.V., Izotova L.S., Mirochnitchenko O.V., Esterova E., Dickensheets H., Donnelly R.P., et al. Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes. J. Biol. Chem. 276(4):2001 (Jan. 26);2725-2732
37. Vieira P., de Waal-Malefyt R., Dang M.N., Johnson K.E., Kastelein R., Fiorentino D.F., et al. Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. Proc. Natl. Acad. Sci. U. S. A. 88(4):1991 (Feb. 15);1172-1176
38. Kotenko S.V., Saccani S., Izotova L.S., Mirochnitchenko O.V., Pestka S. Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10). Proc. Natl. Acad. Sci. U. S. A. 97(4):2000 (Feb. 15);1695-1700
39. Lee H.J., Essani K., Smith G.L. The genome sequence of Yaba-like disease virus, a yatapoxvirus. Virology. 281(2):2001 (Mar. 15);170-192
40. Waldmann T.A., Tagaya Y. The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens. Annu. Rev. Immunol. 17:1999;19-49
41. Nishimura H., Yajima T., Naiki Y., Tsunobuchi H., Umemura M., Itano K., et al. Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo. J. Exp. Med. 191(1):2000 (Jan. 3);157-170
42. Vandenbroeck K., Alloza I., Brehmer D., Billiau A., Proost P., McFerran N., et al. The conserved helix C region in the superfamily of interferon-gamma/interleukin-10-related cytokines corresponds to a high-affinity binding site for the HSP70 chaperone DnaK. J. Biol. Chem. 277(28):2002 (Jul. 12);25668-25676
43. Kotenko S.V., Krause C.D., Izotova L.S., Pollack B.P., Wu W., Pestka S. Identification and functional characterization of a second chain of the interleukin-10 receptor complex. EMBO J. 16(19):1997 (Oct. 1);5894-5903
44. Xie M.H., Aggarwal S., Ho W.H., Foster J., Zhang Z., Stinson J., et al. Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R. J. Biol. Chem. 275(40):2000 (Oct. 6);31335-31339
45. Kotenko S.V., Gallagher G., Baurin V.V., Lewis-Antes A., Shen M., Shah N.K., et al. IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. Nat. Immunol. 4(1):2003 (Jan.);69-77
46. Jotwani R., Palucka A.K., Al-Quotub M., Nouri-Shirazi M., Kim J., Bell D., et al. Mature dendritic cells infiltrate the T cell-rich region of oral mucosa in chronic periodontitis: in situ, in vivo, and in vitro studies. J. Immunol. 167(8):2001 (Oct. 15);4693-4700
47. Wakkach A., Fournier N., Brun V., Breittmayer J.P., Cottrez F., Groux H. Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity. 18(5):2003 (May);605-617
48. Kinane D.F., Hodge P., Eskdale J., Ellis R., Gallagher G. Analysis of genetic polymorphisms at the interleukin-10 and tumour necrosis factor loci in early-onset periodontitis. J. Periodontal Res. 34(7):1999 (Oct.);379-386
49. Eskdale J., McNicholl J., Wordsworth P., Jonas B., Huizinga T., Field M., et al. Interleukin-10 microsatellite polymorphisms and IL-10 locus alleles in rheumatoid arthritis susceptibility. Lancet. 352(9136):1998 (Oct. 17);1282-1283
50. Eskdale J., Wordsworth P., Bowman S., Field M., Gallagher G. Association between polymorphisms at the human IL-10 locus and systemic lupus erythematosus. Tissue Antigens. 49(6):1997 (Jun.);635-639
51. Asadullah K., Eskdale J., Wiese A., Gallagher G., Friedrich M., Sterry W. Interleukin-10 promoter polymorphism in psoriasis. J. Invest. Dermatol. 116(6):2001 (Jun.);975-978
52. Anaya J.M., Correa P.A., Herrera M., Eskdale J., Gallagher G. Interleukin 10 (IL-10) influences autoimmune response in primary Sjogren's syndrome and is linked to IL-10 gene polymorphism. J. Rheumatol. 29(9):2002 (Sep.);1874-1876
53. Gallagher G., Lindemann M., Oh H.H., Ferencik S., Walz M.K., Schmitz A., et al. Association of the TNFa2 microsatellite allele with the presence of colorectal cancer. Tissue Antigens. 50(1):1997 (Jul.);47-51
54. Eskdale J., Keijsers V., Huizinga T., Gallagher G. Microsatellite alleles and single nucleotide polymorphisms (SNP) combine to form four major haplotype families at the human interleukin-10 (IL-10) locus. Genes Immun. 1(2):1999 (Nov.);151-155
55. Jordanides N., Eskdale J., Stuart R., Gallagher G. Allele associations reveal four prominent haplotypes at the human interleukin-6 (IL-6) locus. Genes Immun. 1(7):2000 (Oct.);451-455
56. Eskdale J., Gallagher G., Verweij C.L., Keijsers V., Westendorp R.G., Huizinga T.W. Interleukin 10 secretion in relation to human IL-10 locus haplotypes. Proc. Natl. Acad. Sci. U. S. A. 95(16):1998 (Aug. 4);9465-9470
57. Loe H., Brown L.J. Early onset periodontitis in the United States of America. J. Periodontol. 62(10):1991 (Oct.);608-616
58. Arbuckle M.R., James J.A., Dennis G.J., Rubertone M.V., McClain M.T., Kim X.R., et al. Rapid clinical progression to diagnosis among African-American men with systemic lupus erythematosus. Lupus. 12(2):2003;99-106
59. Yasui D.H., Genetta T., Kadesch T., Williams T.M., Swain S.L., Tsui L.V., et al. Transcriptional repression of the IL-2 gene in Th cells by ZEB. J. Immunol. 160(9):1998 (May 1);4433-4440
60. Gruart-Gouilleux V., Engels P., Sullivan M. Characterization of the human interleukin-5 gene promoter: involvement of octamer binding sites in the gene promoter activity. Eur. J. Immunol. 25(5):1995 (May);1431-1435
61. Tseng Y.H., Schuler L.A. Transcriptional regulation of interleukin-1beta gene by interleukin-1beta itself is mediated in part by Oct-1 in thymic stromal cells. J. Biol. Chem. 273(20):1998 (May 15);12633-12641
62. van Heel D.A., Udalova I.A., De Silva A.P., McGovern D.P., Kinouchi Y., Hull J., et al. Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors. Hum. Mol. Genet. 11(11):2002 (May 15);1281-1289
63. Cron R.Q., Zhou B., Brunvand M.W., Lewis D.B. Octamer proteins inhibit IL-4 gene transcription in normal human CD4 T cells. Genes Immun. 2(8):2001 (Dec.);464-468
64. Salerno M.S., Schwenger G.T., Sanderson C.J., Mordvinov V.A. Binding of octamer factors to the murine IL-5 CLE0 in primary T-cells and a T-cell line. Cytokine. 15(1):2001 (Jul. 7);4-9