C-reactive protein binding to FcγRIIa on human monocytes and neutrophils is allele-specific

Journal of Clinical Investigation

Volumn 105, Issue 3, 2000, Pages 369-376

  Stein, Mary Pat ^a   Edberg, Jeffrey C ^b   Kimberly, Robert P ^b   Mangan, Erin K ^b   Bharadwaj, Dwaipayan ^a   Mold, Carolyn ^a   Du Clos, Terry W ^a,c  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c VA Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CALCIUM; FC RECEPTOR; GAMMA INTERFERON; MONOCLONAL ANTIBODY;

ALLELE; ARTICLE; AUTOIMMUNITY; BINDING AFFINITY; CALCIUM CELL LEVEL; GENETIC POLYMORPHISM; HETEROZYGOTE; HOST RESISTANCE; HUMAN; HUMAN CELL; MONOCYTE; NEUTROPHIL; NORMAL HUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING;

EID: 0033968128     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI7817     Document Type: Article

References (45)

1. Szalai, A.J., Agrawal, A., Greenhough, T.J., and Volanakis, J.E. 1997. C-reactive protein structural biology, gene expression, and host defense function. Immunol. Res. 16:127-136.
2. Osmand, A.P., et al. 1977. Characterization of C-reactive protein and the complement subcomponent Clt as homologous proteins displaying cyclic pentameric symmetry (pentraxins). Proc. Natl. Acad. Sci. USA. 74:739-743.
3. Mortensen, R.F., Osmand, A.P., Lint, T.F., and Gewurz, H. 1976. Interaction of C-reactive protein with lymphocytes and monocytes: complement-dependent adherence and phagocytosis. J. Immunol. 117:774-781.
4. Kindmark, C.-O. 1971. Stimulating effect of C-reactive protein on phagocytosis of various species of pathogenic bacteria. Clin. Exp. Immunol. 8:941-948.
5. Kilpatrick, J.M., and Volanakis, J.E. 1985. Opsonic properties of C-reactive protein. Stimulation by phorbol myristate acetate enables human neutrophils to phagocytize C-reactive protein-coated cells. J. Immunol. 134:3364-3370.
6. Kaplan, M.H., and Volanakis, J.E. 1974. Interactions of C-reactive protein with the complement system. I. Consumption of human complement associated with the reaction of C-reactive protein with pneumococcal polysaccharide and with the choline phosphatides, lecithin and sphingomyelin. J. Immunol. 112:2135-2147.
7. Crowell, R.E. Du Clos, T.W., Montoya, G., Heaphy, E., and Mold, C. 1991. C-reactive protein receptors on the human monocytic cell line U-937. Evidence for additional binding to FcgRI. J. Immunol. 147:3445-3451.
8. Marnell, L.L., Mold, C., Volzer, M.A., Burlingame, R.W., and Du Clos, T.W. 1995. C-reactive protein binds to FcgRI in transfected COS cells. J. Immunol. 155:2185-2193.
9. Tebo, J.M., and Mortensen, R.F. 1990. Characterization and isolation of a C-reactive protein receptor from the human monocytic cell line U-937. J. Immunol. 144:231-238.
10. Zeller, J.M., Kubak, B.M., and Gewurz, H. 1989. Binding sites for C-reactive protein on human monocytes are distinct from IgG Fc receptors. Immunology. 67:51-55.
11. Bharadwaj, D., Stein, M.P., Volzer, M., Mold, C., and Du Clos, T.W. 1999. C-reactive protein binds to FcgRIIA-transfected COS cells. J. Exp. Med. 190:585-590.
12. Clark, M.R., Clarkson, S.B., Ory, P.A., Stollman, N., and Goldstein, L. 1989. Molecular basis for a polymorphism involving Fc receptot II on human monocytes. J. Immunol. 143:1731-1734.
13. Warmerdam, P.A.M. van de Winkel, J.G.J., Vlug, A., Westerdaal, N.A.C., and Capel, P.J.A. 1991. A single amino acid in the second Ig-like domain of the human Fcg receptor II is critical for human IgG2 binding. J. Immunol. 147:1338-1343.
14. Anderson, C.L., Ryan, D.H., Looney, J., and Leary, P.C. 1987. Structural polymorphism of the human monocyte 40 kilodalton Fc receptor for IgG. J. Immunol. 138:2254-2256.
15. 2. J. Clin. Invest. 90:1537-1546.
16. Du Clos, T.W., Zlock, L., and Marnell, L.L. 1991. Definition of a C-reactive protein binding determinant on histones. J. Biol. Chem. 266:2167-1171.
17. Gosselin, E.J., Brown, M.F., Anderson, C.L., Zipf, T.F., and Guyre, P.M. 1990. The monoclonal antibody 41H16 detects the Leu 4 responder form of human FcgRII. J. Immunol. 144:1817-1822.
18. Wu, J., et al. 1997. A novel polymorphism of FcgRIIIa (CD16) alters receptor function and predisposes to autoimmune disease. J. Clin. Invest. 100:1059-1070.
19. Edberg, J.C., et al. 1997. Analysis of Fc gamma RII gene polymorphisms in Wegener's granulomatosis. Exp. Clin. Immunogenet. 14:183-195.
20. Kocher, M., Edberg, J.C., Fleit, H.B., and Kimberly, R.P. 1998. Antineutrophil cytoplasmic antibodies preferentially engage FcgRIIIb on human neutrophils. J. Immunol. 161:6909-6914.
21. 2+ dependence of human Fc gamma receptor-initiated phagocytosis. J. Biol. Chem. 270:22301-22307.
22. 2+ transients. J. Biol. Chem. 273:8071-8079.
23. Guyre, P.M., Morganelli, P.M., and Miller, R. 1983. Recombinant immune interferon increases immunoglobulin G Fc receptors on culture human mononuclear phagocytes. J. Clin. Invest. 72:393-397.
24. Salmon, J.E., Edberg, J.C., Brogle, N.L., and Kimberly, R.P. 1992. Allelic polymorphisms of human Fc gamma receptor IIA and Fc gamma receptor IIIB. J. Clin. Invest. 89:1274-1281.
25. Salmon, J.E., Edberg, J.C., and Kimberly, R.P. 1990. Fcg receptor III on human neutrophils. Allelic variants have functionally distinct capacities. J. Clin. Invest. 85:1287-1295.
26. Mold, C., Nakayama, S., Holzer, T.J., Gewurz, H., and Du Clos, T.W. 1981. C-reactive protein is protective against Streptococcus pneumoniae infection in mice. J. Exp. Med. 154:1703-1708.
27. Szalai, A.J., Briles, D.E., and Volanakis, J.E. 1995. Human C-reactive protein is protective against fatal Streptococcus pneumonia infection in transgenic mice. J. Immunol. 155:2557-2563.
28. Xia, D., and Samols, D. 1997. Transgenic mice expressing rabbit C-reactive protein are resistant to endotoxemia. Proc. Natl. Acad. Sci. USA. 94:2575-2580
29. Heuertz, R.M., Dongyuan, X., Samols, D., and Webster, R.O. 1994. Inhibition of C5a des Arg-induced neutrophil alveolitis in transgenic mice expressing C-reactive protein. Am. J. Pysiol. 266:L649-L654.
30. 2 mice treated with C-reactive protein. Clin. Immunol. Immunopathol. 70:22-27.
31. Gotschlich, E.C., and Edelman, G.M. 1967. Binding properties and specificity of C-reactive protein. Proc. Natl. Acad. Sci. USA. 57:706-712.
32. Volanakis, J.E., and Writz, K.W.A. 1979. Interaction of C-reactive protein with artificial phosphatidylcholine bilayers. Nature. 281:155-157.
33. Li, Y.P., Mold, C., and Du Clos, T.W., 1994. Sublytic complement attack exposes C-reactive protein binding sites on cell membranes. J. Immunol. 152:2995-3005.
34. Robey, F.A., Jones, K.D., Tanaka, T., and Liu, T.-Y. 1984. Binding of C-reactive protein to chromatin and nucleosome core particles. A possible physiological role of C-reactive protein. J. Biol. Chem. 259:731-7316.
35. Du Clos, T.W. 1989. C-reactive protein reacts with the U1 small nuclear ribonucleoprotein. J. Immunol. 143:2553-2559.
36. Stein, M.P., Mold, C., Bharadwaj, D., and Du Clos, T.W. 1999. C-reactive protein (CRP) binding to murine peritoneal cells requires Fc receptors (FcR). FASEB J. 13:A281 (Abstr.)
37. Platonov, A.E., et al. 1998. Association of human FcgRIIa (CD32) polymorphism with susceptibility to and severity of meningococcal disease Clin. Infect Dis. 27:746-750.
38. Bredius, R.G.M., et al. 1994. Fc gamma receptor IIa (CD32) polymorphism in fulminant meningococcal septic shock in children. J. Infect. Dis. 170:848-853.
39. Van der Pol, W.L., and van de Winkel, J.G.J. 1998. IgG receptor polymorphisms: risk factors for disease. Immunogenetics. 48:222-232.
40. Jefferis, R., and Kumararatne, D.S. 1990. Selective IgG subclass deficiency: quantification and clinical relevance. Clin. Exp. Immunol. 81:357-367
41. Tillett, W.S., and Francis, T., Jr. 1930. Serological reactions in pneumonia with a non-protein fraction of pneumococcus. J. Exp. Med. 52:561-571
42. Weiser, J.N., et al. 1998. Phosphorylcholine on the lipopolysaccharide of Haemophilus influenzae contributes to persistence in the respiratory tract and sensitivity to serum killing mediated by C-reactive protein. J. Exp. Med. 187:631-640.
43. Ballou, S.P. and Kushner, I. 1992. C-reactive protein and the acute phase response. Adv. Intern. Med. 37:313-336.
44. Daeron, M. 1997. Fc receptor biology. Annu. Rev. Immunol. 15:203-234.
45. Tax, W.J.M., and van de Winkel, J.G.J. 1990. Human Fc gamma receptor II. A standby receptor activated by proteolysis? Immunol. Today. 11:308-310.