3D-QSAR analysis of conformationally constrained diacylglycerol (DAG) analogues as potent protein kinase C (PK-C) ligands

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 10, 2004, Pages 2639-2644

  Kim, Su Yeon ^a   Lee, Jeewoo ^a  

^a Seoul National University   (South Korea)

Author keywords

Comparative molecular field analysis (CoMFA); Protein kinase C (PK C) ligands; Three dimensional quantitative structure activity relationship (3D QSAR)

Indexed keywords

DIACYLGLYCEROL DERIVATIVE; LIGAND; PROTEIN KINASE C;

ARTICLE; BINDING AFFINITY; DRUG CONFORMATION; ELECTRICITY; PHYSICAL CHEMISTRY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STEREOSPECIFICITY; THREE DIMENSIONAL IMAGING;

DIGLYCERIDES; ELECTROSTATICS; LIGANDS; MOLECULAR CONFORMATION; PROTEIN BINDING; PROTEIN KINASE C; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 2142694334     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.03.016     Document Type: Article

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