Plasma transforming growth factor-β1 in acute viral hepatitis

Medical Science Monitor

Volumn 11, Issue 6, 2005, Pages

  Flisiak, Robert ^a   Prokopowicz, Danuta ^a   Jaroszewicz, Jerzy ^a   Flisiak, Iwona ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Cytokines; Liver; Transforming growth factor 1; Viral hepatitis

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DISEASE COURSE; DISEASE SEVERITY; ENZYME IMMUNOASSAY; FEMALE; FOLLOW UP; HEPATITIS A; HEPATITIS B; HEPATITIS C; HUMAN; LIVER CELL; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PROTEIN FUNCTION; STATISTICAL SIGNIFICANCE; VIRUS HEPATITIS;

ACUTE DISEASE; ADULT; BIOLOGICAL MARKERS; FEMALE; HEPATITIS A; HEPATITIS B; HEPATITIS C; HEPATITIS, VIRAL, HUMAN; HEPATOCYTES; HUMANS; MALE; MIDDLE AGED; REFERENCE VALUES; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 21344471648     PISSN: 12341010     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Gressner AM, Weiskirchen R, Breitkopf K, Dooley S: Roles of TGF-beta in hepatic fibrosis. Front Biosci, 2002; 7: 793-807
2. Flisiak R, Li J, Baraona E, Lieber CS: Effects of ethanol on prostanoids production by liver fat-storing cells. Hepatology, 1993; 18: 153-59
3. Garcia-Trevijano ER, Iraburu MJ, Fontana L et al: Transforming growth factor beta1 induces the expression of alpha1 (I) procollagen mRNA by a hydrogen peroxide-C/EBPbeta-dependent mechanism in rat hepatic stellate cells. Hepatology, 1999; 29: 960-70
4. Pinzani M, Marra F. Cytokine receptors and signaling in hepatic stellate cells. Semin Liver Dis, 2001; 21: 397-416
5. Ramadori G, Saile B: The fibrogenic mediators, TGF-β and TNF-α, as a surviving factors for activated hepatic stellate cells. In: Gressner AM, Heinrich PC, Matern S. eds. Cytokines in liver injury and repair. Dordrecht/Boston/London: Kluwer Academic Publishers, 2002: 184-88
6. Williams EJ, Gaca MD, Brigstock DR et al: Increased expression of connective tissue growth factor in fibrotic human liver and in activated hepatic stellate cells. J Hepatol, 2000; 32: 754-61
7. 1. J Hepatol, 1999; 30: 48-60
8. Nakamura T, Sakata R, Takato U et al: Inhibition of transforming growth factor β prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosantine-treated rats. Hepatology, 2000; 32: 247-55
9. Fausto N: Liver regeneration. J Hepatol, 2000; 32: 19-31
10. Yakicier MC, Irmak MB, Romano A et al: Smad2 and Smad4 gene mutations in hepatocellular carcinoma. Oncogene, 1999; 18: 4879-83
11. Saile B, Matthes N, Knittel T, Ramadori G: Transforming growth factor beta and tumor necrosis factor alpha inhibit both apoptosis and proliferation of activated rat hepatic stellate cells. Hepatology, 1999; 30: 196-202
12. Murphy F, Issa R, Hussain H et al: TIMP-1 and TIMP-2 inhibit apoptosis of human and rat hepatic stellate cells in vitro. Hepatology, 2001; 34: 401A
13. Prudhomme GJ, Piccirillo CA: The inhibitory effects of transforming growth factor-beta-1 (TGF-β1) in autoimmune disease. J Autoimmun, 2000; 14: 23-42
14. Flisiak R, Maxwell P, Prokopowicz D et al: Plasma tissue inhibitor of metalloproteinases-1 and transforming growth factor β1 - possible non-invasive biomarkers of hepatic fibrosis in patients with chronic B and C hepatitis. Hepato-Gastroenterology, 2002; 49: 1369-72
15. Kanzler S, Baumann M, Schirmacher P: Prediction of progressive liver fibrosis in hepatitis C infection by serum and tissue levels of transforming growth factor-beta. J Viral Hepat, 2001; 8: 430-37
16. 1 as an indicator of hepatic function impairment in liver cirrhosis. Cytokine, 2000; 12: 677-81
17. Neuman M, Angulo P, Malkiewicz I et al: Tumor necrosis factor-alpha and transforming growth factor-beta reflect severity of liver damage in primary biliary cirrhosis. J. Gastroenterol Hepatol, 2002; 17: 196-202
18. Chen WX, Li YM, Yu CH et al: Quantitative analysis of transforming growth factor beta 1 mRNA in patients with alcoholic liver disease. World J Gastroenterol, 2002; 8: 379-81
19. George J, Roulot D, Kateliansky VE, Bissell DM: In vivo inhibition of rat stellate cell activation by soluble transforming growth factor β type II receptor: a potential new therapy for hepatic fibrosis. Proc Natl Acad Sci USA, 1999; 96: 12719-24
20. Nakamura T, Ushiyama C, Suzuki S et al: Effect of plasma exchange on serum tissue inhibitor of metalloproteinase 1 and cytokine concentrations in patients with fulminant hepatitis. Blood Purif, 2000; 18: 50-54
21. Roulot D, Sevesik AM, Coste T et al: Role of transforming growth factor β type II receptor in hepatic fibrosis: Studies of human chronic hepatitis C and experimental fibrosis in rats. Hepatology, 1999; 29: 1730-38
22. Koulentaki M, Valatas V, Xidakis K et al: Matrix metalloproteinases and their inhibitors in acute viral hepatitis. J Viral Hepat, 2002; 9: 189-93
23. Grainger DJ, Mosedale DE, Metcalfe JC: TGF-β in blood: a complex problem. Cytokine & Growth Fact Rev, 2000; 11: 133-45
24. Miwa Y, Ellis AJ, Hughes RD et al: Effect of ELAD liver support on plasma HGF and TGF-beta 1 in acute liver failure. Int J Artif Organs, 1990; 19: 240-44
25. Yoo YD, Ueda H, Park K et al: Regulation of transforming growth factor-beta 1 expression by the hepatitis B virus (HBV) X transactivator. Role in HBV pathogenesis. J Clin Invest, 1990; 97: 388-95
26. Lee DK, Park SH, Yi Y et al: The hepatitis B virus encoded oncoprotein pX amplifies TGF-beta family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus - induced liver fibrosis. Genes Dev, 2001; 15: 455-66
27. Date M, Matsuzaki K, Matsushita M et al: Modulation of transforming growth factor beta function in hepatocytes and hepatic stellate cells in rat liver injury. Gut, 2000; 46: 719-24
28. Letterio JJ, Roberts AB; Regulation of immune responses by TGF-β. Ann Rev Immunol, 1998; 16: 137-61