메뉴 건너뛰기




Volumn 48, Issue 6, 2005, Pages 1059-1065

Hyperinsulinaemia triggered by dietary conjugated linoleic acid is associated with a decrease in leptin and adiponectin plasma levels and pancreatic beta cell hyperplasia in the mouse

Author keywords

Adipokines; Conjugated linoleic acid; Hepatic steatosis; Insulin resistance; Insulin secretion; Pancreatic beta cells

Indexed keywords

ADIPONECTIN; CARBACHOL; LEPTIN; LINOLEIC ACID; LIPID;

EID: 21344469235     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-005-1765-8     Document Type: Article
Times cited : (84)

References (31)
  • 1
    • 3242884783 scopus 로고    scopus 로고
    • Conjugated linoleic acid and obesity control: Efficacy and mechanisms
    • Wang YW, Jones PJ (2004) Conjugated linoleic acid and obesity control: efficacy and mechanisms. Int J Obes Relat Metab Disord 28: 941-955
    • (2004) Int J Obes Relat Metab Disord , vol.28 , pp. 941-955
    • Wang, Y.W.1    Jones, P.J.2
  • 2
    • 0033861304 scopus 로고    scopus 로고
    • Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice
    • Tsuboyama-Kasaoka N, Takahashi M, Tanemura K et al (2000) Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice. Diabetes 49:1534-1542
    • (2000) Diabetes , vol.49 , pp. 1534-1542
    • Tsuboyama-Kasaoka, N.1    Takahashi, M.2    Tanemura, K.3
  • 3
    • 0036739536 scopus 로고    scopus 로고
    • Dietary trans-10,cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse
    • Clément L, Poirier H, Niot I et al (2002) Dietary trans-10,cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse. J Lipid Res 43:1400-1409
    • (2002) J Lipid Res , vol.43 , pp. 1400-1409
    • Clément, L.1    Poirier, H.2    Niot, I.3
  • 4
    • 3042769523 scopus 로고    scopus 로고
    • Effects of two conjugated linoleic acid isomers on body fat mass in overweight humans
    • Malpuech-Brugere C, Verboeket-van de Venne WP, Mensink RP et al (2004) Effects of two conjugated linoleic acid isomers on body fat mass in overweight humans. Obes Res 12:591-598
    • (2004) Obes Res , vol.12 , pp. 591-598
    • Malpuech-Brugere, C.1    Verboeket-Van De Venne, W.P.2    Mensink, R.P.3
  • 5
    • 0141528782 scopus 로고    scopus 로고
    • Dietary conjugated linoleic acids as free fatty acids and triacylglycerols similarly affect body composition and energy balance in mice
    • Terpstra AH, Javadi M, Beynen AC et al (2003) Dietary conjugated linoleic acids as free fatty acids and triacylglycerols similarly affect body composition and energy balance in mice. J Nutr 133:3181-3186
    • (2003) J Nutr , vol.133 , pp. 3181-3186
    • Terpstra, A.H.1    Javadi, M.2    Beynen, A.C.3
  • 6
    • 0347093594 scopus 로고    scopus 로고
    • Efficacy and safety of dietary supplements containing CLA for the treatment of obesity: Evidence from animal and human studies
    • Larsen TM, Toubro S, Astrup A (2003) Efficacy and safety of dietary supplements containing CLA for the treatment of obesity: evidence from animal and human studies. J Lipid Res 44:2234-2241
    • (2003) J Lipid Res , vol.44 , pp. 2234-2241
    • Larsen, T.M.1    Toubro, S.2    Astrup, A.3
  • 7
    • 0036730666 scopus 로고    scopus 로고
    • Treatment with dietary trans10cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome
    • Riserus U, Arner P, Brismar K et al (2002) Treatment with dietary trans10cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome. Diabetes Care 25:1516-1521
    • (2002) Diabetes Care , vol.25 , pp. 1516-1521
    • Riserus, U.1    Arner, P.2    Brismar, K.3
  • 8
    • 0033636780 scopus 로고    scopus 로고
    • Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice
    • Shimomura I, Matsuda M, Hammer RE et al (2000) Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. Mol Cell 6:77-86
    • (2000) Mol Cell , vol.6 , pp. 77-86
    • Shimomura, I.1    Matsuda, M.2    Hammer, R.E.3
  • 9
    • 0032532152 scopus 로고    scopus 로고
    • Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: Model for congenital generalized lipodystrophy
    • Shimomura I, Hammer RE, Richardson JA et al (1998) Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy. Genes Dev 12:3182-3194
    • (1998) Genes Dev , vol.12 , pp. 3182-3194
    • Shimomura, I.1    Hammer, R.E.2    Richardson, J.A.3
  • 10
    • 0031441286 scopus 로고    scopus 로고
    • Troglitazone action is independent of adipose tissue
    • Burant CF, Sreenan S, Hirano K et al (1997) Troglitazone action is independent of adipose tissue. J Clin Invest 100:2900-2908
    • (1997) J Clin Invest , vol.100 , pp. 2900-2908
    • Burant, C.F.1    Sreenan, S.2    Hirano, K.3
  • 11
    • 0032532753 scopus 로고    scopus 로고
    • Life without white fat: A transgenic mouse
    • Moitra J, Mason MM, Olive M et al (1998) Life without white fat: a transgenic mouse. Genes Dev 12:3168-3181
    • (1998) Genes Dev , vol.12 , pp. 3168-3181
    • Moitra, J.1    Mason, M.M.2    Olive, M.3
  • 12
    • 0033965557 scopus 로고    scopus 로고
    • Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice
    • Gavrilova O, Marcus-Samuels B, Graham D et al (2000) Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice. J Clin Invest 105:271-278
    • (2000) J Clin Invest , vol.105 , pp. 271-278
    • Gavrilova, O.1    Marcus-Samuels, B.2    Graham, D.3
  • 13
    • 17944365228 scopus 로고    scopus 로고
    • The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
    • Yamauchi T, Kamon J, Waki H et al (2001) The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nature Med 7:941-946
    • (2001) Nature Med , vol.7 , pp. 941-946
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3
  • 14
    • 0033517284 scopus 로고    scopus 로고
    • Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy
    • Shimomura I, Hammer RE, Ikemoto S et al (1999) Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy. Nature 401:73-76
    • (1999) Nature , vol.401 , pp. 73-76
    • Shimomura, I.1    Hammer, R.E.2    Ikemoto, S.3
  • 15
    • 0031793899 scopus 로고    scopus 로고
    • Inhibition of insulin secretion by leptin in normal rodent islets of Langerhans
    • Poitout V, Rouault C, Guerre-Millo M et al (1998) Inhibition of insulin secretion by leptin in normal rodent islets of Langerhans. Endocrinology 139:822-826
    • (1998) Endocrinology , vol.139 , pp. 822-826
    • Poitout, V.1    Rouault, C.2    Guerre-Millo, M.3
  • 16
    • 0035145780 scopus 로고    scopus 로고
    • Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids
    • Briaud I, Harmon JS, Kelpe CL et al (2001) Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids. Diabetes 50:315-321
    • (2001) Diabetes , vol.50 , pp. 315-321
    • Briaud, I.1    Harmon, J.S.2    Kelpe, C.L.3
  • 17
    • 0002814160 scopus 로고
    • Nouveau procédé d'extraction des lipides du sérum par le méthylal. Application aux microdosages du cholestérol total, des phospholipides et des protéines
    • Paris
    • Delsal JL (1944) Nouveau procédé d'extraction des lipides du sérum par le méthylal. Application aux microdosages du cholestérol total, des phospholipides et des protéines [Article in French]. Bull Soc Chim Biol (Paris) 26:99-105
    • (1944) Bull Soc Chim Biol , vol.26 , pp. 99-105
    • Delsal, J.L.1
  • 18
    • 1842530442 scopus 로고    scopus 로고
    • Hepatic steatosis is not due to impaired fatty acid oxidation capacities in C57BL/6J mice fed the conjugated trans-10, cis-12-isomer of linoleic acid
    • Degrace P, Demizieux L, Gresti J, Chardigny JM, Sebedio JL, Clouet P (2004) Hepatic steatosis is not due to impaired fatty acid oxidation capacities in C57BL/6J mice fed the conjugated trans-10, cis-12-isomer of linoleic acid. J Nutr 134:861-867
    • (2004) J Nutr , vol.134 , pp. 861-867
    • Degrace, P.1    Demizieux, L.2    Gresti, J.3    Chardigny, J.M.4    Sebedio, J.L.5    Clouet, P.6
  • 19
    • 0031454125 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes
    • Kirchgessner TG, Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS (1997) Tumor necrosis factor-alpha contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytes. J Clin Invest 100:2777-2782
    • (1997) J Clin Invest , vol.100 , pp. 2777-2782
    • Kirchgessner, T.G.1    Uysal, K.T.2    Wiesbrock, S.M.3    Marino, M.W.4    Hotamisligil, G.S.5
  • 21
    • 0037459090 scopus 로고    scopus 로고
    • Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes
    • Fasshauer M, Kralisch S, Klier M et al (2003) Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes. Biochem Biophys Res Commun 301:1045-1050
    • (2003) Biochem Biophys Res Commun , vol.301 , pp. 1045-1050
    • Fasshauer, M.1    Kralisch, S.2    Klier, M.3
  • 22
    • 0037677767 scopus 로고    scopus 로고
    • Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors
    • Iwaki M, Matsuda M, Maeda N et al (2003) Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors. Diabetes 52:1655-1663
    • (2003) Diabetes , vol.52 , pp. 1655-1663
    • Iwaki, M.1    Matsuda, M.2    Maeda, N.3
  • 23
    • 0035980729 scopus 로고    scopus 로고
    • Influence of conjugated linoleic acid on body composition and target gene expression in peroxisome proliferator-activated receptor alpha-null mice
    • Peters JM, Park Y, Gonzalez FJ, Pariza MW (2001) Influence of conjugated linoleic acid on body composition and target gene expression in peroxisome proliferator-activated receptor alpha-null mice. Biochim Biophys Acta 1533:233-242
    • (2001) Biochim Biophys Acta , vol.1533 , pp. 233-242
    • Peters, J.M.1    Park, Y.2    Gonzalez, F.J.3    Pariza, M.W.4
  • 24
    • 0036851817 scopus 로고    scopus 로고
    • Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
    • Yamauchi T, Kamon J, Minokoshi Y et al (2002) Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 8:1288-1295
    • (2002) Nat Med , vol.8 , pp. 1288-1295
    • Yamauchi, T.1    Kamon, J.2    Minokoshi, Y.3
  • 25
    • 0141739735 scopus 로고    scopus 로고
    • Isomer-specific regulation of metabolism and PPARgamma signaling by CLA in human preadipocytes
    • Brown JM, Boysen MS, Jensen SS et al (2003) Isomer-specific regulation of metabolism and PPARgamma signaling by CLA in human preadipocytes. J Lipid Res 44:1287-1300
    • (2003) J Lipid Res , vol.44 , pp. 1287-1300
    • Brown, J.M.1    Boysen, M.S.2    Jensen, S.S.3
  • 26
    • 2942755860 scopus 로고    scopus 로고
    • Conjugated linoleic acid (CLA) induces human adipocyte delipidation: Autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines
    • Brown JM, Boysen MS, Chung S et al (2004) Conjugated linoleic acid (CLA) induces human adipocyte delipidation: autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines. J Biol Chem 279:26735-26747
    • (2004) J Biol Chem , vol.279 , pp. 26735-26747
    • Brown, J.M.1    Boysen, M.S.2    Chung, S.3
  • 27
    • 0141450254 scopus 로고    scopus 로고
    • Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis
    • Rosen ED, Kulkarni RN, Sarraf P et al (2003) Targeted elimination of peroxisome proliferator-activated receptor gamma in beta cells leads to abnormalities in islet mass without compromising glucose homeostasis. Mol Cell Biol 23:7222-7229
    • (2003) Mol Cell Biol , vol.23 , pp. 7222-7229
    • Rosen, E.D.1    Kulkarni, R.N.2    Sarraf, P.3
  • 28
    • 0032938104 scopus 로고    scopus 로고
    • Conjugated linoleic acid rapidly reduces body fat content in mice without affecting energy intake
    • DeLany JP, Blohm F, Truett AA, Scimeca JA, West DB (1999) Conjugated linoleic acid rapidly reduces body fat content in mice without affecting energy intake. Am J Physiol 276:R1172-R1179
    • (1999) Am J Physiol , vol.276
    • DeLany, J.P.1    Blohm, F.2    Truett, A.A.3    Scimeca, J.A.4    West, D.B.5
  • 29
    • 0034042959 scopus 로고    scopus 로고
    • Islet growth and development in the adult
    • Bonner-Weir S (2000) Islet growth and development in the adult. J Mol Endocrinol 24:297-302
    • (2000) J Mol Endocrinol , vol.24 , pp. 297-302
    • Bonner-Weir, S.1
  • 30
    • 0033856731 scopus 로고    scopus 로고
    • Conjugated linoleic acid supplementation in humans: Effects on circulating leptin concentrations and appetite
    • Medina EA, Horn WF, Keim NL et al (2000) Conjugated linoleic acid supplementation in humans: effects on circulating leptin concentrations and appetite. Lipids 35:783-788
    • (2000) Lipids , vol.35 , pp. 783-788
    • Medina, E.A.1    Horn, W.F.2    Keim, N.L.3
  • 31
    • 17144434666 scopus 로고    scopus 로고
    • Supplementation with trans10cis12-conjugated linoleic acid induces hyperproinsulinaemia in obese men: Close association with impaired insulin sensitivity
    • Riserus U, Vessby B, Arner P, Zethelius B (2004) Supplementation with trans10cis12-conjugated linoleic acid induces hyperproinsulinaemia in obese men: close association with impaired insulin sensitivity. Diabetologia 47:1016-1019
    • (2004) Diabetologia , vol.47 , pp. 1016-1019
    • Riserus, U.1    Vessby, B.2    Arner, P.3    Zethelius, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.