Centrosome impairments and consequent cytokinesis defects are possible mechanisms of taxane drugs

Anticancer Research

Volumn 25, Issue 3 B, 2005, Pages 1919-1925

  Zhu, Jun ^a   Beattie, Eric C ^a   Yang, Yang ^a   Wang, Hui Juan ^a   Seo, Jae Young ^a   Yang, Li Xi ^a,b  

^a CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^b ST MARY S MEDICAL CENTER   (United States)

Author keywords

Midbody; Mitotic catastrophe; Mitotic spindle; Multinucleation; Taxol; Taxotere

Indexed keywords

ANTINEOPLASTIC AGENT; BETA TUBULIN; CELL PROTEIN; DOCETAXEL; GAMMA TUBULIN; PACLITAXEL; PERICENTRIN; TAXANE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL ASSAY; CELL CYCLE; CELL DEATH; CELL DIVISION; CELL STRAIN PC 3; CELL ULTRASTRUCTURE; CENTROSOME; CHROMOSOME SEGREGATION; CONTROLLED STUDY; CYTOKINESIS; DISSOCIATION; DOSE RESPONSE; DRUG EXPOSURE; DRUG MECHANISM; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; INTERPHASE; LOW DRUG DOSE; MICROTUBULE ASSEMBLY; MITOSIS; MITOSIS SPINDLE; MULTINUCLEAR CELL; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL DEATH; CELL LINE, TUMOR; CELL NUCLEUS; CENTROSOME; CYTOKINESIS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; MALE; MITOTIC SPINDLE APPARATUS; NEOPLASMS, HORMONE-DEPENDENT; PACLITAXEL; PROSTATIC NEOPLASMS; TAXOIDS;

EID: 21344461192     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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