Proinflammatory effects of LIGHT through HVEM and LTβR interactions in cultured human umbilical vein endothelial cells

Journal of Biomedical Science

Volumn 12, Issue 2, 2005, Pages 363-375

  Chang, Ying Hsin ^a   Shie, Liang Hsieh ^b,c,d   Chao, Yee ^e   Yang, Chieh Chou ^b   Wan, Wan Lin ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c GENOMICS RESEARCH CENTER   (Taiwan)

^d TAIPEI CITY HOSPITAL   (Taiwan)

^e TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Endothelial cells; HVEM; Inflammation; LIGHT; Lymphotoxin beta receptor

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; PROTEIN; PROTEIN LIGHT; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; BINDING AFFINITY; CELL DEATH; CELL SURFACE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATORY CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; UMBILICAL VEIN;

CELL ADHESION; CELL DEATH; CELL LINE; CELLS, CULTURED; CHEMOKINES, CXC; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPOPROSTENOL; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERFERON TYPE II; INTERLEUKIN-8; LYMPHOTOXIN BETA RECEPTOR; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MONOCYTES; NF-KAPPA B; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECEPTORS, CELL SURFACE; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, MEMBER 14; RECEPTORS, TUMOR NECROSIS FACTOR, MEMBER 6B; RECEPTORS, VIRUS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14; TUMOR NECROSIS FACTOR-ALPHA; UMBILICAL VEINS; UP-REGULATION; VASCULAR CELL ADHESION MOLECULE-1;

HERPESVIRIDAE;

EID: 21244497570     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1007/s11373-005-1360-5     Document Type: Article

References (39)

1. R.M. Locksley N. Killeen M.J. Lenardo 2001 The TNF and TNF receptor superfamilies: integrating mammalian biology Cell 104 487 501
2. R.I. Montgomery M.S. Warner B. Lum P.G. Spear 1996 Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family Cell 87 427 436
3. J.J. Oppenheim C.O. Zachariae N. Mukaida K. Matsushima 1991 Properties of the novel proinflammatory supergene "intercrine" cytokine family Annu. Rev. Immunol. 9 617 648
4. P.D. Crowe T.L. VanArsdale B.N. Walter C.F. Ware C. Hession B. Ehrenfels J.L. Browning W.S. Din R.G. Goodwin C.A. Smith 1994 A lymphotoxin-beta-specific receptor Science 264 707 710
5. Y. Zhai R. Guo T.L. Hsu G.L. Yu J. Ni B.S. Kwon G.W. Jiang J. Lu J. Tan M. Ugustus K. Carter L. Rojas F. Zhu C. Lincoln G. Endress L. Xing S. Wang K.O. Oh R. Gentz S. Ruben M.E. Lippman S.L. Hsieh D. Yang 1998 LIGHT, a novel ligand for lymphotoxin beta receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer J. Clin. Invest. 102 1142 1151
6. K.Y. Yu B. Kwon J. Ni Y. Zhai R. Ebner B.S. Kwon 1999 A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis J. Biol. Chem. 274 13733 137366
7. J.L. Browning K. Miatkowski I. Sizing D.A. Griffiths M. Zafari C.D. Benjamin W. Meier F. Mackay 1996 Signaling through the lymphotoxin beta receptor induces the death of some adenocarcinoma tumor lines J. Exp. Med. 183 867 878
8. M.C. Chen M.J. Hwang Y.C. Chou W.H. Chen G. Cheng H. Nakano T.Y. Luh S.C. Mai S.L. Hsieh 2003 The role of apoptosis signal-regulating kinase 1 in lymphotoxin-beta receptor-mediated cell death J. Bio. Chem. 278 16073 16081
9. M.A. Degli-Esposti T. Davis-Smith W.S. Din P.J. Smolak R.G. Goodwin C.A. Smith 1997 Activation of the lymphotoxin beta receptor by cross-linking induces chemokine production and growth arrest in A375 melanoma cells J. Immunol. 158 1756 1762
10. I.A. Rooney K.D. Butrovich A.A. Glass S. Borboroglu C.A. Benedict J.C. Whitbeck G.H. Cohen R.J. Eisenberg C.F. Ware 2000 The lymphotoxin-beta receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells J. Biol. Chem. 275 14307 14315
11. S. Scheu J. Alferink T. Potzel W. Barchet U. Kalinke K. Pfeffer 2002 Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesis J. Exp. Med. 195 1613 1624
12. J.L. Gommerman J.L. Browning 2003 Lymphotoxin/LIGHT, lymphoid microenvironments and autoimmune disease Nature Rev. Immunol. 3 642 655
13. J. Wang A. Foster R. Chin P. Yu Y. Sun Y. Wang K. Pfeffer Y.X. Fu 2002 The complementation of lymphotoxin deficiency with LIGHT, a newly discovered TNF family member, for the restoration of secondary lymphoid structure and function Eur. J. Immunol. 32 1969 1979
14. S.W. Granger S. Rickert 2003 LIGHT-HVEM signaling and the regulation of T cell-mediated immunity Cytokine Growth Factor Rev. 14 289 296
15. J.A. Harrop P.C. McDonnell M. Brigham-Burke S.D. Lyn J. Minton K.B. Tan K. Dede J. Spampanato C. Silverman P. Hensley R. DiPrinzio J.G. Emery K. Deen C. Eichman M. Chabot-Fletcher A. Truneh P.R. Young 1998 Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth J. Biol. Chem. 273 27548 27556
16. K. Tamada K. Shimozaki A.I. Chapoval Y. Zhai J. Su S.F. Chen S.L. Hsieh S. Nagata J. Ni L. Chen 2000 LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell response J. Immunol. 164 4105 4110
17. H. Kosuge J.I. Suzuki T. Kakuta G. Haraguchi N. Koga H. Futamatsu R. Gotoh M. Inobe M. Isobe T. Uede 2004 Attenuation of graft arterial disease by manipulation of the LIGHT pathway Arterioscler. Thromb. Vasc. Biol. 24 1 8
18. K. Tamada K. Shimozaki A.I. Chapoval G. Zhu G. Sica D. Flies T. Boone G. Hsu Y.X. Fu S. Nagata J. Ni L. Chen 2000 Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway Nat. Med. 6 283 289
19. Q. Ye C.C. Fraser W. Gao L. Wang S.J. Busfield C. Wang Y. Qiu A.J. Coyle J.C. Gutierrez-Ramos W.W. Hancock 2002 Modulation of LIGHT-HVEM costimulation prolongs cardiac allograft survival J. Exp. Med. 195 795 800
20. W.H. Lee S.H. Kim Y. Lee B.B. Lee B. Kwo H. Song B.S. Kwon J.E. Park 2001 Tumor necrosis factor receptor superfamily 14 is involved in atherogenesis by inducing proinflammatory cytokines and matrix metalloproteinases Artherioscler Thromb. Vasc. Biol. 21 2004 2010
21. C. Michiels 2003 Endothelial cell functions J. Cell. Physiol. 196 430 443
22. F.W. Luscinskas M.A. Jr. Gimbrone 1996 Endothelial-dependent mechanisms in chronic inflammatory leukocyte recruitment Annu. Rev. Med. 47 413 421
23. T. Imaizumi T. Matsumiya K. Fujimoto K. Okamoto X. Cui U. Ohtaki H. Yoshida K. Satoh 2000 Interferon stimulates the expression of CX3CL1/fractalkine in cultured human endothelial cells J. Exp. Med. 192 127 139
24. A.D. Luster J.V. Ravetch 1987 Biochemical characterization of a gamma interferon-inducible cytokine (IP-10) J. Exp. Med. 166 1084 1097
25. G.R. Stark I.M. Kerr B.R. Williams R.H. Silverman R.D. Schreiber 1998 How cells respond to interferons Annu. Rev. Biochem. 67 227 264
26. Y.H. Chang Y. Chao S.L. Hsieh W.W. Lin 2004 Mechanism of LIGHT/interferon-gamma-induced cell death in HT-29 cells J. Cell. Biochem. 93 1188 1202
27. X. Xin Z.A. Khan S. Chen S. Chakrabarti 2004 Extracellular signal-regulated kinase (ERK) in glucose-induced and endothelin-mediated fibronectin synthesis Lab. Invest. 84 1451 1459
28. A. Mantovani F. Bussolino M. Introna 1997 Cytokine regulation of endothelial cell function: from molecular level to the bedside Immunol. Today 18 231 240
29. M.C. Chen T.L. Hsu T.Y. Luh S.L. Hsieh 2000 Overexpression of bcl-2 enhances LIGHT- and interferon-gamma-mediated apoptosis in Hep3BT2 cells J. Biol. Chem. 275 38794 34801
30. M. Zhang R. Guo Y. Zhai X.Y. Fu D. Yang 2003 LIGHT stimulates IFNgamma-mediated intercellular adhesion molecule-1 upregulation of cancer cells Hum. Immunol. 64 416 426
31. Y.H. Chang S.L. Hsieh M.C. Chen W.W. Lin 2002 Lymphotoxin beta receptor induces interleukin 8 gene expression via NF-κB and AP-1 activation Exp. Cell Res. 278 166 174
32. S.L. Kunkel R.M. Strieter I.J.D. Lindley J. Westwick 1995 Chemokines: new ligands, receptors and activities Immunol. Today 16 559 561
33. J.S. Levine 1995 Bronchial epithelial cell-cytokine interactions in airway inflammation J. Invest. Med. 43 241 249
34. V.N. Ngo H. Korner M.D. Gunn K.N. Schmidt D.S. Riminton M.D. Cooper J.L. Browning J.D. Sedgwick J.G. Cyster 1999 Lymphotoxin αβ and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen J. Exp. Med. 189 403 412
35. W.L. Smith D.L. Dewitt 1996 Prostaglandin endoperoxide H synthases-1 and -2 Adv. Immunol. 62 167 215
36. M.Y. Wu P.Y. Wang S.H. Han S.L. Hsieh 1999 The cytoplasmic domain of the lymphotoxin-beta receptor mediates cell death in HeLa cells J. Biol. Chem. 274 11868 11873
37. G. Tellides D.A. Tereb N.C. Kirkiles-Smith R.W. Kim J.H. Wilson J.S. Schechner M.I. Lorber J.S. Pober 2000 Interferon-γ elicits arteriosclerosis in the absence of leukocytes Nature 403 207 211
38. D.N. Mauri R. Ebner R.I. Montgomery K.D. Kochel T.C. Cheung G.L. Yu S. Ruben M. Murphy R.J. Eisenberg G.H. Cohen P.G. Spear C.F. Ware 1998 LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator Immunity 8 21 30
39. J. Wang J.C. Lo A. Foster P. Yu H.M. Chen Y. Wang K. Tamada L. Chen Y.X. Fu 2001 The regulation of T cell homeostasis and autoimmunity by T cell-derived LIGHT J. Clin. Invest. 108 1771 1780