Rhodopsin phosphorylation in rats exposed to intense light

Photochemistry and Photobiology

Volumn 81, Issue 3, 2005, Pages 541-547

  Ablonczy, Z ^a,d   Darrow, R M ^b   Knapp, D R ^c   Organisciak, D T ^b   Crouch, R K ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b WRIGHT STATE UNIVERSITY   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RHODOPSIN;

ANIMAL; CHEMISTRY; CIRCADIAN RHYTHM; CONFERENCE PAPER; DARK ADAPTATION; LIGHT; MASS SPECTROMETRY; METABOLISM; PHOSPHORYLATION; PIGMENT EPITHELIUM; RADIATION EXPOSURE; RADIATION INJURY; RAT;

ANIMALS; CIRCADIAN RHYTHM; DARK ADAPTATION; LIGHT; MASS SPECTROMETRY; PHOSPHORYLATION; PIGMENT EPITHELIUM OF EYE; RADIATION INJURIES, EXPERIMENTAL; RATS; RHODOPSIN;

EID: 21244465526     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1562/2004-08-27-RA-294.1     Document Type: Conference Paper

References (38)

1. Noell, W. K., V. S. Walker, B. S. Kang and S. Berman (1966) Retinal damage by light in rats. Invest. Ophthalmol. 5, 450-473.
2. Williams, T. P. and W. L. Howell (1983) Action spectrum of retinal light-damage in albino rats. Invest. Ophthalmol. Vis. Sci. 24, 285-287.
3. Ablonczy, Z., D. R. Knapp, R. Darrow, D. T. Organisciak and R. K. Crouch (2000) Mass spectrometric analysis of rhodopsin from light damaged rats. Mol. Vis. 6, 109-115.
4. Hao, W., A. Wenzel, M. S. Obin, C. K. Chen, E. Brill, N. V. Krasnoperova, P. Eversole-Cire, Y. Kleyner, A. Taylor, M. I. Simon, C. Grimm, C. E. Reme and J. Lem (2002) Evidence for two apoptotic pathways in light-induced retinal degeneration. Nat. Genet. 32, 254-260.
5. Kuhn, H. and U. Wilden (1987) Deactivation of photoactivated rhodopsin by rhodopsin-kinase and arrestin. J. Recept. Res. 7, 283-298.
6. Chen, C. K., M. E. Burns, M. Spencer, G. A. Niemi, J. Chen, J. B. Hurley, D. A. Baylor and M. I. Simon (1999) Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase. Proc. Natl. Acad. Sci. USA 96, 3718-3722.
7. Mendez, A., M. E. Burns, A. Roca, J. Lem, L. W. Wu, M. I. Simon, D. A. Baylor and J. Chen (2000) Rapid and reproducible deactivation of rhodopsin requires multiple phosphorylation sites. Neuron 28, 153-164.
8. Kennedy, M. J., K. A. Lee, G. A. Niemi, K. B. Craven, G. G. Garwin, J. C. Saari and J. B. Hurley (2001) Multiple phosphorylation of rhodopsin and the in vivo chemistry underlying rod photoreceptor dark adaptation. Neuron 31, 87-101.
9. Kuhn, H., J. H. Cook and W. J. Dreyer (1973) Phosphorylation of rhodopsin in bovine photoreceptor membranes. A dark reaction after illumination. Biochemistry 12, 2495-2502.
10. Gibson, S. K., J. H. Parkes and P. A. Liebman (2000) Phosphorylation modulates the affinity of light-activated rhodopsin for G protein and arrestin. Biochemistry 39, 5738-5749.
11. Cornwall, M. C., H. R. Matthews, R. K. Crouch and G. L. Fain (1995) Bleached pigment activates transduction in salamander cones. J. Gen. Physiol. 106, 543-557.
12. Abdulaev, N. G., T. Ngo, R. Chen, Z. Lu and K. D. Ridge (2000) Functionally discrete mimics of light-activated rhodopsin identified through expression of soluble cytoplasmic domains. J. Biol. Chem. 275, 39354-39363.
13. Ohguro, H. and M. Nakazawa (2002) Pathological roles of recoverin in cancer-associated retinopathy. Adv. Exp. Med. Biol. 514, 109-124.
14. Alloway, P. G., L. Howard and P. J. Dolph (2000) The formation of stable rhodopsin-arrestin complexes induces apoptosis and photoreceptor cell degeneration. Neuron 28, 129-138.
15. Bernstein, P. S., W. C. Law and R. R. Rando (1987) Isomerization of all-trans-retinoids to 11-cis-retinoids in vitro. Proc. Natl. Acad. Sci. USA 84, 1849-1853.
16. Redmond, T. M., S. Yu, E. Lee, D. Bok, D. Hamasaki, N. Chen, P. Goletz, J. X. Ma, R. K. Crouch and K. Pfeifer (1998) Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle. Nat. Genet. 20, 344-351.
17. Saari, J. C., M. Nawrot, B. N. Kennedy, G. G. Garwin, J. B. Hurley, J. Huang, D. E. Possin and J. W. Crabb (2001) Visual cycle impairment in cellular retinaldehyde binding protein (CRALBP) knockout mice results in delayed dark adaptation. Neuron 29, 739-748.
18. Ablonczy, Z., R. K. Crouch, P. W. Goletz, T. M. Redmond, D. R. Knapp, J. X. Ma and B. Rohrer (2002) 11-ds-retinal reduces constitutive opsin phosphorylation and improves quantum catch in retinoid-deficient mouse rod photoreceptors. J. Biol. Chem. 277, 40491-40498.
19. Grimm, C., A. Wenzel, F. Hafezi, S. Yu, T. M. Redmond and C. E. Reme (2000) Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration. Nat. Genet. 25, 63-66.
20. Organisciak, D. T., R. M. Darrow, L. Barsalou, R. K. Kutty and B. Wiggert (2000) Circadian-dependent retinal light damage in rats. Invest. Ophthalmol. Vis. Sci. 41, 3694-3701.
21. Organisciak, D. T., A. Xie, H. M. Wang, Y. L. Jiang, R. M. Darrow and L. A. Donoso (1991) Adaptive changes in visual cell transduction protein levels: effect of light. Exp. Eye Res. 53, 773-779.
22. Ball, L. E., J. E. Oatis, Jr., K. Dharmasiri, M. Busman, J. Wang, L. B. Cowden, A. Galijatovic, N. Chen, R. K. Crouch and D. R. Knapp (1998) Mass spectrometric analysis of integral membrane proteins: application to complete mapping of bacteriorhodopsins and rhodopsin. Protein Sci. 7, 758-764.
23. Lee, K. A., K. B. Craven, G. A. Niemi and J. B. Hurley (2002) Mass spectrometric analysis of the kinetics of in vivo rhodopsin phosphorylation. Protein Sci. 11, 862-874.
24. Baehr, W., J. D. Falk, K. Bugra, J. T. Triantafyllos and J. F. McGinnis (1988) Isolation and analysis of the mouse opsin gene. FEBS Lett. 238, 253-256.
25. Papac, D. I., J. E. Oatis, Jr., R. K. Crouch and D. R. Knapp (1993) Mass spectrometric identification of phosphorylation sites in bleached bovine rhodopsin. Biochemistry 32, 5930-5934.
26. Vaughan, D. K., J. L. Nemke, S. J. Fliesler, R. M. Darrow and D. T. Organisciak (2002) Evidence for a circadian rhythm of susceptibility to retinal light damage. Photochem. Photobiol. 75, 547-553.
27. Crouch, R. K. and J. X. Ma (2000) The role of vitamin A in visual transduction. In Vitamin A and Retinoids: An Update of Biological Aspects and Clinical Applications (Edited by Livrea, M. A.), pp. 59-72. Birkhäuser Verlag, Basel, Switzerland.
28. Ohguro, H., M. Rudnicka-Nawrot, J. Buczylko, X. Zhao, J. A. Taylor, K. A. Walsh and K. Palczewski (1996) Structural and enzymatic aspects of rhodopsin phosphorylation. J. Biol. Chem. 271, 5215-5224.
29. Ohguro, H., R. S. Johnson, L. H. Ericsson, K. A. Walsh and K. Palczewski (1994) Control of rhodopsin multiple phosphorylation. Biochemistry 33, 1023-1028.
30. Udovichenko, I. P., A. C. Newton and D. S. Williams (1997) Contribution of protein kinase C to the phosphorylation of rhodopsin in intact retinas. J. Biol. Chem. 272, 7952-7959.
31. Palczewski, K., P. A. Hargrave, J. H. McDowell and T. S. Ingebritsen (1989) The catalytic subunit of phosphatase 2A dephosphorylates phosphoopsin. Biochemistry 28, 415-419.
32. Brown, B. M., B. L. Carlson, X. Zhu, R. N. Lolley and C. M. Craft (2002) Light-driven translocation of the protein phosphatase 2A complex regulates light/dark dephosphorylation of phosducin and rhodopsin. Biochemistry 41, 13526-13538.
33. Beatrice, J., A. Wenzel, C. E. Reme and C. Grimm (2003) Increased light damage susceptibility at night does not correlate with RPE65 levels and rhodopsin regeneration in rats. Exp. Eye Res. 76, 695-700.
34. Naash, M. L., N. S. Peachey, Z. Y. Li, C. C. Gryczan, Y. Goto, J. Blanks, A. H. Milam and H. Ripps (1996) Light-induced acceleration of photoreceptor degeneration in transgenic mice expressing mutant rhodopsin. Invest. Ophthalmol. Vis. Sci. 37, 775-782.
35. Wang, M., T. T. Lam, M. O. Tso and M. I. Naash (1997) Expression of a mutant opsin gene increases the susceptibility of the retina to light damage. Vis. Neurosci. 14, 55-62.
36. Liu, X., P. Garriga and H. G. Khorana (1996) Structure and function in rhodopsin: correct folding and misfolding in two point mutants in the intradiscal domain of rhodopsin identified in retinitis pigmentosa. Proc. Natl. Acad. Sci. USA 93, 4554-4559.
37. Ranchon, I., M. M. La Vail, Y. Kotake and R. E. Anderson (2003) Free radical trap phenyl-N-tert-butylnitrone protects against light damage but does not rescue P23H and S334ter rhodopsin transgenic rats from inherited retinal degeneration. J. Neurosci. 23, 6050-6057.
38. Kaldi, I., M. Dittmar, P. Pierce and R. E. Anderson (2003) L-NAME protects against acute light damage in albino rats, but not against retinal degeneration in P23H and S334ter transgenic rats. Exp. Eye Res. 76, 453-461.