Synthesis of new Mannich bases of arylpyridazinones as analgesic and anti-inflammatory agents

Arzneimittel-Forschung/Drug Research

Volumn 55, Issue 6, 2005, Pages 318-325

  Gökçe, Mehtap ^a   Bakir, Gökçen ^a   Şahin, Mustafa Fethi ^a   Küpeli, Esra ^a   Yeşilada, Erdem ^a  

^a GAZI UNIVERSITY   (Turkey)

Author keywords

3(2H) Pyridazinones; Analgesics; Anti inflammatories; Arylpyridazinones, analgesic activity, anti inflammatory activity, Mannich bases, synthesis

Indexed keywords

1,4 BENZOQUINONE; 2 [[4 (4 FLUOROPHENYL) 1 PIPERAZINYL]METHYL] 6 (4 METHOXYPHENYL) 3(2H) PYRIDAZINONE; ACETYLSALICYLIC ACID; ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; CARRAGEENAN; INDOMETACIN; MANNICH BASE; PYRIDAZINONE DERIVATIVE; UNCLASSIFIED DRUG;

ABDOMINAL PAIN; ACUTE TOXICITY; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; MALE; NONHUMAN; PAW EDEMA; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STOMACH ULCER; WRITHING TEST;

EID: 21244439936     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296866     Document Type: Article

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