Synthesis and analgesic and antiinflammatory activity of methyl 6-substituted-3(2H)-pyridazinone-2-ylacetate derivatives

Archiv der Pharmazie

Volumn 337, Issue 8, 2004, Pages 445-452

  Sahin M F ^a   Badiccoglu B ^a   Gökçe, Mehtap ^a   Kupeli E ^a   Yesilada E ^a  

^a GAZI UNIVERSITY   (Turkey)

Author keywords

3(H) Pyridazinones; Analgesic activity; Anti inflammatory activity; Arylpiperazinylpyridazinones

Indexed keywords

ACETYLSALICYLIC ACID; CARRAGEENAN; INDOMETACIN; METHYL 6 (4 BENZYL 1 PIPERAZINYL) 3(2H) PYRIDAZINON 2 YLACETATE; METHYL 6 (4 CINNAMYL 1 PIPERAZINYL) 3(2H) PYRIDAZINON 2 YLACETATE; METHYL 6 (4 PHENYL 1 PIPERAZINYL) 3(2H) PYRIDAZINON 2 YLACETATE; METHYL 6 (4 PIPERONYL 1 PIPERAZINYL) 3(2H) PYRIDAZINON 2 YLACETATE; METHYL 6 [4 (2 ETHOXYPHENYL) 1 PIPERAZINYL] 3(2H) PYRIDAZINON 2 YLACETATE; METHYL 6 [4 (2 FLUOROPHENYL) 1 PIPERAZINYL] 3(2H) PYRIDAZINON 2 YLACETATE; METHYL 6 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 3(2H) PYRIDAZINON 2 YLACETATE; METHYL 6 [4 (2 PYRIDYL) 1 PIPERAZINYL] 3(2H) PYRIDAZINON 2 YLACETATE; METHYL 6 [4 (2,3 DIMETHYLPHENYL) 1 PIPERAZINYL] 3(2H) PYRIDAZINON 2 YLACETATE; METHYL 6 [4 (4 FLUOROPHENYL) 1 PIPERAZINYL] 3(2H) PYRIDAZINON 2 YLACETATE; METHYL 6 [4 (4 NITROPHENYL) 1 PIPERAZINYL] 3(2H) PYRIDAZINON 2 YLACETATE; NONSTEROID ANTIINFLAMMATORY AGENT; PHENYLQUINONE; PYRIDAZINONE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; DRUG SYNTHESIS; GASTROINTESTINAL TOXICITY; INFLAMMATION; INFRARED SPECTROSCOPY; MALE; MOUSE; NONHUMAN; PAIN; PAW EDEMA; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STOMACH MUCOSA; STOMACH ULCER; STRUCTURE ACTIVITY RELATION; ULCEROGENESIS; WRITHING TEST;

ACETATES; ANALGESICS, NON-NARCOTIC; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; EDEMA; MALE; MICE; MOLECULAR WEIGHT; PAIN MEASUREMENT; PYRIDAZINES; STOMACH ULCER;

EID: 4544317208     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.200400896     Document Type: Article

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