Optimization of the medium perfusion rate in a packed-bed bioreactor charged with CHO cells

Cytotechnology

Volumn 46, Issue 1, 2004, Pages 37-47

  Meuwly, F ^a   Von Stockar, U ^b   Kadouri, A ^a  

^a MERCK SERONO S A   (Switzerland)

^b EPFL   (Switzerland)

Author keywords

Bioreactor; CHO; Continuous; Fibra Cel ; Packed bed; Perfusion rate; Recombinant protein; Serum free medium; Upstream process

Indexed keywords

DIMER; GLYCAN; PROTEIN; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CELL DENSITY; CHO CELL; CONTINUOUS CULTURE; CONTROLLED STUDY; COST CONTROL; CULTURE MEDIUM; ECONOMICS; INTERMETHOD COMPARISON; NONHUMAN; PACKED BED REACTOR; PERFUSION; PILOT STUDY; PROCESSING; PRODUCTIVITY; PROTEIN ANALYSIS; PROTEIN QUALITY; PURIFICATION; SIALYLATION; VOLUMETRY;

EID: 21244437617     PISSN: 09209069     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10616-005-2105-z     Document Type: Article

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