Metabolism of 2α-propoxy-1α,25-dihydroxyvitamin D3 and 2α-(3-hydroxypropoxy)-1α,25-dihydroxyvitamin D3 by human CYP27A1 and CYP24A1

Drug Metabolism and Disposition

Volumn 33, Issue 6, 2005, Pages 778-784

  Abe, Daisuke ^a   Sakaki, Toshiyuki ^b   Kusudo, Tatsuya ^a   Kittaka, Atsushi ^c   Saito, Nozomi ^c   Suhara, Yoshitomo ^c   Fujishima, Toshie ^c   Takayama, Hiroaki ^c   Hamamoto, Hiromi ^a   Kamakura, Masaki ^b   Ohta, Miho ^d   Inouye, Kuniyo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^c TEIKYO UNIVERSITY   (Japan)

^d Koshien Junior College   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2ALPHA (3 HYDROXYPROPOXY) 1ALPHA,25 DIHYDROXYVITAMIN D3; 2ALPHA PROPOXY 1ALPHA,25 DIHYDROXYVITAMIN D3; C 301; CYTOCHROME P450; CYTOCHROME P450 24A1; CYTOCHROME P450 27A1; O 2C3; UNCLASSIFIED DRUG; VITAMIN D DERIVATIVE; VITAMIN D RECEPTOR;

ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BINDING; DRUG METABOLISM; HUMAN; METABOLIC ACTIVATION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPECIES DIFFERENCE;

ANIMALS; CATTLE; CYTOCHROME P-450 CYP27A1; CYTOCHROME P-450 ENZYME SYSTEM; DIHYDROXYCHOLECALCIFEROLS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; ISOENZYMES; RATS; SPECIES SPECIFICITY; STEROID HYDROXYLASES;

ANIMALIA;

EID: 21044450310     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.104.003038     Document Type: Article

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