Metabolism of 26,26,26,27,27,27-F6-1α,25-dihydroxyvitamin D3 by CYP24: Species-based difference between humans and rats

Biochemical Pharmacology

Volumn 65, Issue 12, 2003, Pages 1957-1965

  Sakaki, Toshiyuki ^a   Sawada, Natsumi ^a   Abe, Daisuke ^a   Komai, Koichiro ^b   Shiozawa, Shunichi ^b   Nonaka, Yasuki ^c   Nakagawa, Kimie ^d   Okano, Toshio ^d   Ohta, Miho ^e   Inouye, Kuniyo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KOSHIEN UNIVERSITY   (Japan)

^d KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^e Koshien Junior College   (Japan)

Author keywords

CYP24; Cytochrome P450; Hexafluoro 1 ,25 dihydroxyvitamin D3; Metabolism of Vitamin D; Species based difference; Vitamin D analog

Indexed keywords

ADRENODOXIN; CYTOCHROME P450 24; DRUG METABOLITE; FALECALCITRIOL; FERREDOXIN NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCTASE; PROTEIN; UNCLASSIFIED DRUG; VITAMIN D DERIVATIVE; VITAMIN D RECEPTOR;

ARTICLE; BINDING AFFINITY; CHEMICAL BOND; DRUG ACTIVITY; DRUG METABOLISM; DRUG RECEPTOR BINDING; ESCHERICHIA COLI; EXPRESSION VECTOR; MOLECULAR WEIGHT; PRIORITY JOURNAL; TARGET ORGAN;

EID: 0037716243     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00190-4     Document Type: Article

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