A novel homogenous assay for topoisomerase II action and inhibition

ChemBioChem

Volumn 6, Issue 5, 2005, Pages 920-926

  Jahnz, Michael ^a   Medina, Miguel Ángel ^b   Schwille, Petra ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF MÁLAGA   (Spain)

Author keywords

Antitumor agents; Flourescence spectroscopy; High throughput screening; Inhibitors; Topoisomerase

Indexed keywords

AMSACRINE; ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE (ATP HYDROLYSING); DOUBLE STRANDED DNA; GYRASE INHIBITOR; NOVOBIOCIN;

ACCURACY; ARTICLE; BACTERIOPHAGE T4; CELL GROWTH; DNA CLEAVAGE; DUAL COLOR FLUORESCENCE CROSS CORRELATION SPECTROSCOPY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; FLUORESCENCE SPECTROSCOPY; HIGH THROUGHPUT SCREENING; MODEL; NEOPLASM; PRIORITY JOURNAL; PROTEIN EXPRESSION;

CATALYSIS; DIFFUSION; DNA; DNA TOPOISOMERASES, TYPE II; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; MODELS, BIOLOGICAL; NOVOBIOCIN; TIME FACTORS;

EID: 21044441216     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200400379     Document Type: Article

References (31)

1. J. J. Wang, Q. Rev. Biophys. 1998, 31, 107-144.
2. J. L. Nitiss, Biochim. Biophys, Acta 1998, 1400, 63-81.
3. U. Kellner, M. Sehested, P. B. Jensen, F. Gieseler, P. Rudolph, Lancet Oncol. 2002, 3, 235-243.
4. J. M. Berger, S. J. Gamblin, S. C. Harrison, J. C. Wang, Nature 1996, 379, 225-232.
5. J. M. Berger, Biochim. Biophys. Acta 1998, 1400, 3-18.
6. T. Andoh, R. Ishida, Biochim. Biophys. Acta 1998, 1400, 155-171.
7. D. A. Burden, N. Osheroff, Biochim. Biophys. Acta 1998, 1400, 139-154.
8. T. K. Li, L. F. Liu, Annu. Rev. Pharmacol. Toxicol. 2001, 47, 53-77.
9. S. H. Kaufmann, Biochim. Biophys. Acta 1998, 1400, 195-211.
10. B. A. Stohr, K. N. Kreuzer, Genetics 2001, 158, 19-28.
11. S. H. Neece, K. Carles-Kinch, D. J. Tomso, K. N. Kreuzer, Mol. Microbiol. 1996, 20, 1145-1154.
12. J.V. Walker, J. L. Nitiss, Cancer Invest. 2002, 20, 570-589.
13. Z. Topcu, J. Clin. Pharm. Ther. 2001, 26, 405-416.
14. K. R. Hande, Biochim. Biophys. Acta 1998, 1400, 173-184.
15. J. M. Fortune, N. Osheroff, J. Biol. Chem. 1998, 273, 17643-17650.
16. M. Gellert, M. H. O'Dea, T. Itoh, J. Tomizawa, Proc. Natl. Acad. Sci. USA 1976, 73, 4474-4478.
17. T. R. Hammonds, A. Maxwell, J. R. Jenkins, Antimicrob. Agents Chemother. 1998, 42, 889-894.
18. N. Barnabe, B. B. Hasinoff, J. Chromatogr. B 2001, 760, 263-269.
19. P. Schwille, F. J. Meyer-Almes, R. Rigler, Biophys. J. 1997, 72, 1878-1886.
20. M. A. Medina, P. Schwille, Bioessays 2002, 24, 758-764.
21. K. Bacia, P. Schwille, Methods 2003, 29, 74-85.
22. E. Haustein, P. Schwille, Methods 2003, 29, 153-166.
23. M. Rarbach, U. Kettling, A. Koltermann, M. Eigen, Methods 2001, 24, 104-116.
24. C. H. Freudenreich, K. N. Kreuzer, Proc. Natl. Acad. Sci. USA 1994, 91, 11007-11011.
25. A. C. Huff, K. N. Kreuzer, J. Biol. Chem. 1990, 265, 20496-20505.
26. K. N. Kreuzer, Adv. Pharmacol. 1994, 29B, 171-186.
27. K. N. Kreuzer, Biochim. Biophys. Acta 1998, 1400, 339-347.
28. C. H. Freudenreich, K. N. Kreuzer, EMBO J. 1993, 12, 2085-2097.
29. A. Haldane, D. M. Sullivan, Methods Mol. Biol. 2001, 95, 13-23.
30. A. Koltermann, U. Kettling, J. Bieschke, T. Winkler, M. Eigen, Proc. Natl. Acad. Sci. USA 1998, 95, 1421-1426.
31. T. Winkler, U. Kettling, A. Koltermann, M. Eigen, Proc. Natl. Acad. Sci. USA 1999, 96, 1375-1378.