Role of protein kinase C-δ (PKC-δ) in the generation of the effects of IFN-α in chronic myelogenous leukemia cells

Experimental Hematology

Volumn 33, Issue 5, 2005, Pages 550-557

  Kaur, Surinder ^a   Parmar, Simrit ^a   Smith, Jessica ^a   Katsoulidis, Efstratios ^a   Li, Yongzhong ^a   Sassano, Antonella ^a   Majchrzak, Beata ^b,c   Uddin, Shahab ^d   Tallman, Martin S ^a   Fish, Eleanor N ^b,c   Platanias, Leonidas C ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b Centre for Innovation in Complex Care   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; METHYLCELLULOSE; PROTEIN KINASE C DELTA; ROTTLERIN; SERINE; STAT1 PROTEIN;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; CHRONIC MYELOID LEUKEMIA; CLONOGENIC ASSAY; COLONY FORMING UNIT GM; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; INTERFERON PRODUCTION; LYMPHOCYTE CULTURE; MYELOID PROGENITOR CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

EID: 20944452041     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2005.01.014     Document Type: Article

References (52)

1. S. Pestka, J.A. Langer, K.C. Zoon, and C.E. Samuel Interferons and their actions Annu Rev Biochem 56 1987 727 777
2. J.E. Darnell Jr., I.M. Kerr, and G.R. Stark Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins Science 264 1994 1415 1420
3. G.R. Stark, I.M. Kerr, B.R. Williams, R.H. Silverman, and R.D. Schreiber How cells respond to interferons Annu Rev Biochem 67 1998 227 264
4. L.C. Platanias, and E.N. Fish Signaling pathways activated by interferons Exp Hematol 27 1999 1583 1592
5. L.C. Platanias The p38 mitogen-activated protein kinase pathway and its role in interferon signaling Pharmacol Ther 98 2003 129 142
6. S. Uddin, L. Yenush, X.-J. Sun, M.E. Sweet, M.F. White, and L.C. Platanias Interferon-α engages the insulin receptor substrate-1 to associate with the phosphatidylinositol 3'-kinase J Biol Chem 270 1995 15938 15941
7. L.C. Platanias, S. Uddin, A. Yetter, X.-J. Sun, and M.F. White The type I interferon receptor mediates tyrosine phosphorylation of insulin receptor substrate 2 J Biol Chem 271 1996 278 282
8. S. Uddin, E.N. Fish, D. Sher, C. Gardziola, M.F. White, and L.C. Platanias Activation of the phosphatidylinositol 3-kinase serine kinase by IFN-α J Immunol 158 1997 2390 2397
9. S. Uddin, E.N. Fish, and D. Sher The IRS-Pathway operates distinctively from the Stat-pathway in hematopoietic cells and transduces common and distinct signals during engagement of the insulin or interferon-α receptors Blood 90 1997 2574 2582
10. S. Ahmad, Y. Alsayed, B.J. Druker, and L.C. Platanias The type I interferon receptor mediates tyrosine phosphorylation of the CrkL adaptor protein J Biol Chem 272 1997 29991 29994
11. E.N. Fish, S. Uddin, M. Korkmaz, B. Majchrzak, B.J. Druker, and L.C. Platanias Activation of a CrkL-stat5 signaling complex by type I interferons J Biol Chem 274 1999 571 573
12. Y. Alsayed, S. Uddin, and S. Ahmad IFN-γ activates the C3G/Rap1 signaling pathway J Immunol 164 2000 1800 1806
13. M. David, E. Petricoin, C. Benjamin, R. Pine, M.J. Weber, and A.C. Larner Requirement for MAP kinase (ERK2) activity in interferon-α and interferon-β-stimulated gene expression through STAT proteins Science 269 1995 1721 1723
14. S. Uddin, B. Majchrzak, and J. Woodson Activation of the p38 mitogen-activated protein kinase by type I interferons J Biol Chem 274 1999 30127 30131
15. K.C. Goh, and S.J. Haque Williams BRG. p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons EMBO J 18 1999 5601 5608
16. S. Uddin, F. Lekmine, and N. Sharma The Rac1/p38 mitogen-activated protein kinase pathway is required for interferon α-dependent transcriptional activation but not serine phosphorylation of Stat proteins J Biol Chem 275 2000 27634 27640
17. I.A. Mayer, A. Verma, and I.M. Grumbach The p38 MAPK pathway mediates the growth inhibitory effects of interferon-α in BCR-ABL-expressing cells J Biol Chem 276 2001 28570 28577
18. A. Verma, D.K. Deb, and A. Sassano Activation of the p38 mitogen-activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factor-β on normal hematopoiesis J Biol Chem 277 2002 7726 7735
19. Y. Li, A. Sassano, and B. Majchrzak Role of p38α Map kinase in Type I interferon signaling J Biol Chem 279 2004 970 979
20. M. Wetzler, H. Kantarjian, and M. Talpaz Interferon-α therapy for chronic myelogenous leukemia Am J Med 99 1995 402 411
21. A. Verma, and L.C. Platanias Signaling via the interferon-α receptor in chronic myelogenous leukemia cells Leuk Lymphoma 43 2002 703 709
22. Z. Wen, Z. Zhong, and J.E. Darnell Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation Cell 28 1995 241 250
23. X. Zhu, Z. Wen, L.Z. Xu, and J.E. Darnell Jr. Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase Mol Cell Biol 17 1997 6618 6623
24. J.J. Zhang, Y. Zhao, and B.T. Chait Ser727-dependent recruitment of MCM5 by Stat1α in IFN-γ-induced transcriptional activation EMBO J 17 1998 6963 6971
25. Z. Wen, and J.E. Darnell Jr. Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3 Nucleic Acids Res 25 1997 2062 2067
26. C.M. Horvath, and J.E. Darnell Jr. The antiviral state induced by α interferon and γ interferon requires transcriptionally active Stat1 protein J Virol 70 1996 647 650
27. H. Nguyen, C.V. Ramana, J. Bayes, and G.R. Stark Roles of phosphatidylinositol 3-kinase in interferon-γ-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression J Biol Chem 276 2001 33361 33368
28. A. Yetter, S. Uddin, J.J. Krolewski, H. Jiao, T. Yi, and L.C. Platanias Association of the interferon-dependent tyrosine kinase Tyk-2 with the hematopoietic cell phosphatase J Biol Chem 270 1995 18179 18182
29. S. Uddin, A. Chamdin, and L.C. Platanias Interaction of the transcriptional activator Stat-2 with the type I interferon receptor J Biol Chem 270 1995 24627 24630
30. S. Uddin, A. Sassano, and D.K. Deb Protein kinase C-δ (PKC-δ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727 J Biol Chem 277 2002 14408 14416
31. D.K. Deb, A. Sassano, and F. Lekmine Activation of protein kinase C δby IFN-γ J Immunol 171 2003 267 273
32. S. Parmar, E. Katsoulidis, and A. Verma Role of the p38 mitogen-activated protein kinase pathway in the generation of the effects of imatinib mesylate (STI571) in BCR-ABL-expressing cells J Biol Chem 279 2004 25345 25352
33. N. Jain, T. Zhang, W. Hua, W. Li, and X. Cao Protein kinase C δ associates with and phosphorylates Stat3 in an interleukin-6-dependent manner J Biol Chem 274 1999 24392 24400
34. M. Gschwendt, H.J. Muller, and K. Kielbassa Rottlerin, a novel protein kinase inhibitor Biochem Biophys Res Commun 199 1994 93 98
35. A. Rahman, K.N. Anwar, and S. Uddin Protein kinase C-δ regulates thrombin-induced ICAM-1 gene expression in endothelial cells via activation of p38 mitogen-activated protein kinase Mol Cell Biol 21 2001 5554 5565
36. K. Yanagisawa, H. Yamauchi, M. Kaneko, H. Kohno, H. Hasegawa, and S. Fujita Suppression of cell proliferation and the expression of a bcr-abl fusion gene and apoptotic cell death in a new human chronic myelogenous leukemia cell line, KT-1, by interferon-α Blood 91 1998 641 648
37. I.M. Grumbach, I.A. Mayer, and S. Uddin Engagement of the CrkL adaptor in interferon α signaling in BCR-ABL-expressing cells Br J Haematol 112 2001 327 336
38. A.S. Kristof, J. Marks-Konczalik, E. Billings, and J. Moss Stimulation of signal transducer and activator of transcription-1 (STAT1)-dependent gene transcription by lipopolysaccharide and interferon-γ is regulated by mammalian target of rapamycin J Biol Chem 278 2003 33637 33644
39. A.C. Newton Regulation of protein kinase C Curr Opin Cell Biol 9 1997 161 167
40. H. Mellor, and P.J. Parker The extended protein kinase C superfamily Biochem J 332 1998 281 292
41. L.C. Platanias Map kinase signaling pathways and hematologic malignancies Blood 101 2003 4667 4679
42. B.J. Druker, M. Talpaz, and D.J. Resta Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia N Engl J Med 344 2001 1031 1037
43. S.G. O'Brien, F. Guilhot, and R.A. Larson Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia N Engl J Med 348 2003 994 1004
44. T. Shimizu, Y. Miyakawa, A. Oda, M. Kizaki, and Y. Ikeda STI571-resistant KT-1 cells are sensitive to interferon-α accompanied by the loss of T-cell protein tyrosine phosphatase and prolonged phosphorylation of Stat1 Exp Hematol 31 2003 601 608
45. S. Landolfo, A. Guarini, and L. Riera Chronic myeloid leukemia cells resistant to interferon-α lack STAT1 expression Hematol J 1 2000 7 14
46. Y. Li, K.K. Srivastava, and L.C. Platanias Mechanisms of type I interferon signaling in normal and malignant cells Arch Immunol Ther Exp (Warsz) 52 2004 156 163
47. P.J. Parker, and J. Murray-Rust PKC at a glance J Cell Sci 117 2004 131 132
48. U. Kikkawa, H. Matsuzaki, and T. Yamamoto Protein kinase C δ (PKC δ): activation mechanisms and functions J Biochem 132 2002 831 839
49. H. Mischak, J. Goodnight, and W. Kolch Overexpression of protein kinase C-δ and -ε in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity J Biol Chem 268 1993 6090 6096
50. Z. Lu, A. Hornia, Y.-W. Jiang, Q. Zang, S. Ohno, and D.A. Foster Tumor promotion by depleting cells of protein kinase C δ Mol Cell Biol 17 1997 3418 3428
51. P.J. Redding, N.E. Dreckschmidt, and H. Ahrens Transgenic mice overexpressing protein kinase C-δ in the epidermis are resistant to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate Cancer Res 59 1999 5710 5718
52. S. Kambhampati, Y. Li, and A. Verma Activation of protein kinase C δ by all-trans-retinoic acid J Biol Chem 278 2003 32544 32551