On how insulin may influence ageing and become atherogenic throughout the insulin-like growth factor-1 receptor pathway: In vitro studies with human vascular smooth muscle cells

Gerontology

Volumn 51, Issue 4, 2005, Pages 225-230

  Ruiz Torres, Antonio ^a,b   Lozano, Rosario ^a   Melón, José ^a   Carraro, Raffaele ^a  

^a HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^b Inst Univ Invest Gerontologica M   (Spain)

Author keywords

Insulin; Insulin like growth factor 1; Phenotype; Receptors; Smooth muscle cells

Indexed keywords

ANTIBODY; BROXURIDINE; DNA; INSULIN; INSULIN RECEPTOR; SOMATOMEDIN C RECEPTOR;

AGING; ARTICLE; ATHEROGENESIS; CELL CULTURE; CELL DIFFERENTIATION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOGENESIS; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

AGING; ARTERIOSCLEROSIS; CELL MOVEMENT; HUMANS; INSULIN; MITOGENS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION;

EID: 20944450899     PISSN: 0304324X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000085118     Document Type: Article

References (41)

1. Stout RW: Hyperinsulinemia and atherosclerosis. Diabetes 1996;45(suppl 3):45-46.
2. Cullen K, Stenhouse NS, Wearne KL, Welborn TA: Multiple regression analysis of risk factors for cardiovascular disease and cancer mortality in Busselton, Western Australia: 13-year study. J Chronic Dis 1983;36:371-377.
3. Pyorala K, Savolainen E, Kaukolas S, Haapakoski J: Plasma insulin as coronary heart disease risk factor: Relationship to other risk factors and predictive value during 91/2-year follow up of the Helsinki Policeman Study population. Acta Med Scand Suppl 1985;701:38-52.
4. Reaven G: Metabolic syndrome: Pathophysiology and implications for management of cardiovascular disease. Circulation 2002;106:286-288.
5. Valek J, Valkova L, Vlasakova Z, Topinka V: Increased fibrinogen levels in the offspring of hypertensive men. Relation with hyperinsulinemia and the metabolic syndrome. Arterioscler Thromb Vasc Biol 1995;15:2229-2233.
6. Baillie GM, Sherer JT, Weart CW: Insulin and coronary artery disease: Is syndrome X the unifying hypothesis? Ann Pharmacother 1998;32: 233-247.
7. Ross R: Atherosclerosis - An inflammatory disease. N Engl J Med 1999;340:115-126.
8. Bayes-Genis A, Conover CA, Schwartz RS: The insulin-like growth factor axis: A review of atherosclerosis and restenosis. Circ Res 2000;86:125-130.
9. Ross R: The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature 1993;362:801-809.
10. Brizzi MF, Formato L, Dentelli P, Rosso A, Pavan M, Garbarino G, Pegoraro M, Camussi G, Pegoraro L: Interleukin-3 stimulates migration and proliferation of vascular smooth muscle cells: A potential role in atherogenesis. Circulation 2001;103:549-554.
11. Denger S, Jahn L, Wende P, Watson L, Gerber SH, Kubler W, Kreuzer J: Expression of monocyte chemoattractant protein-1 cDNA in vascular smooth muscle cells. Induction of the synthetic phenotype: A possible clue to SMC differentiation in the process of atherogenesis. Atherosclerosis 1999;144:15-23.
12. Kraemer R: Regulation of cell migration in atherosclerosis. Curr Atheroscler Rep 2000;2:445-452.
13. Clowes AW, Schwartz SM: Significance of quiescent smooth muscle migration in the injured rat carotid artery. Circ Res 1985;56:139-145.
14. Owens GK, Kumar MS, Wamhoff BR: Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 2004;84:767-801.
15. Minamino T, Miyauchi H, Yoshida T, Tateno K, Kunieda T, Komuro I: Vascular cell senescence and vascular aging. J Mol Cell Cardiol 2004;36:175-183.
16. Nakashima H, Ozono R, Suyama C, Sueda T, Kambe M, Oshima T: Telomere attrition in white blood cell correlating with cardiovascular damage. Hypertens Res 2004;27:319-325.
17. Serrano AL, Andres V: Telomeres and cardiovascular disease: Does size matter? Circ Res 2004;94:575-584.
18. Ruiz-Torres A, Melón J, Muñoz FJ: Insulin stimulates collagen synthesis in vascular smooth muscle cells from elderly patients. Gerontology 1998;44:144-148.
19. Muñoz FJ, Jimenez M, Melón J, Ruiz-Torres A: Phenotypic changes in vascular smooth muscle cells during aging: Insulin effect on migration. Gerontology 1998;44:149-152.
20. Li Z, Alavi MZ, Moore S: The proliferation of neointimal smooth muscle cells cultured from rabbit aortic explants after deendothelialization by a balloon catheter. Int J Exp Pathol 1994;75:169-177.
21. Donath MY, Gosteli-Peter MA, Mauri C, Froesch ER, Zapf J: Insulin-like growth factor-I stimulates myofibrillar genes and modulates atrial natriuretic factor MRNA in rat heart. Eur J Endocrinol 1997;137:309-315.
22. Liu X, Lin CS, Spencer EM, Lue TF: Insulin-like growth factor-I promotes proliferation and migration of cavernous smooth muscle cells. Biochem Biophys Res Commun 2001;280:1307-1315.
23. Li Q, Li B, Wang X Leri A, Jana KP, Liu Y, Kajstura J, Baserga R, Anversa P: Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy. J Clin Invest 1997;100:1991-1999.
24. Jung F, Haendeler J, Goebel C, Zeiher AM, Dimmeler S: Growth factor-induced phosphoinositide 3-OH kinase/Akt phosphorylation in smooth muscle cells: Induction of cell proliferation and inhibition of cell death. Cardiovasc Res 2000;48:148-157.
25. Thyberg J: Differentiated properties and proliferation of arterial smooth muscle cells in culture. Int Rev Cytol 1996;169:183-265.
26. Berfield AK, Raugi GJ, Abrass ChK: Insulin induces rapid and specific rearrangement of the skeleton of rat mesangial cells in vitro. J Histochem Cytochem 1996;44:91-101.
27. Bretscher MS: Getting membrane flow and the cytoskeleton to cooperate in moving cells. Cell 1996;87:601-606.
28. Stossel ThP: On the crawling of animal cells. Science 1993;260:1096-1094.
29. Ruiz-Torres A, Lozano R, Melon J, Carraro R: L-calcium channel blockade induced by diltiazem inhibits proliferation, migration and F-actin membrane rearrangements in human vascular smooth muscle cells stimulated with insulin and IGF-1. Int J Clin Pharmacol Ther 2003;41:386-391.
30. Okura Y, Brink M, Zahid AA, Anwar A, Delafontaine P: Decreased expression of insulin-like growth factor-1 and apoptosis of vascular smooth muscle cells in human atherosclerotic plaque. J Mol Cell Cardiol 2001;33:1777-1789.
31. Rudman D, Mattson DE: Serum insulin-like growth factor I in healthy older men in relation to physical activity. J Am Geriatr Soc 1994;42:71-76.
32. Ruiz-Torres A: The role of insulin-like growth factor 1 and insulin in ageing and atherosclerosis. Novartis Found Symp 2002;242:143-160.
33. Arcaro G, Cretti A, Balzano S, Lechi A, Muggeo M, Bonora E, Bonadonna RC: Insulin causes endothelial dysfunction in human: Sites and mechanisms. Circulation 2002;105:576-582.
34. Iida KT, Suzuki H, Sone H, Shimano H, Toyoshima H. Yatoh S, Asano T, Okuda Y, Yamada N: Insulin inhibits apoptosis of macrophage cell line, THP-1 cells, via phosphatidylinositol-3-kinase-dependent pathway. Arterioscler Thromb Vasc Biol 2002;22:380-386.
35. Rizzoni D, Porteri E, Giustina A, De Ciuceis C, Sleiman I, Boari GE, Castellano M, Muiesan ML, Bonadonna S, Burattin A, Cerudelli B, Agabiti-Rosei E: Acromegalic patients show the presence of hypertrophic remodeling of subcutaneous small resistance arteries. Hypertension 2004;43:561-565.
36. Lin VK, Wang D, Lee IL, Vasquez D, Fagelson JE, McConnell JD: Myosin heavy chain gene expression in normal and hyperplastic human prostate tissue. Prostate 2000;44:193-203.
37. Kondo T, Vicent D, Suzuma K, Vanagisawa M, King GL, Holzenberger M, Kahn CR: Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization. J Clin Invest 2003;111:1835-1842.
38. Holzenberger M, Dupont J, Ducos B, Leneuve P, Géloë A, Even PC, Cervera P, Le Bouc Y: IGF-1 receptor regulates life span and resistance to oxidative stress in mice. Nature 2003;421:182-187.
39. Dewsn M, Nishimoto I, Baserga R: IGF-1 receptor protection from apoptosis in cells lacking the IRS proteins. Recept Signal Transduct 1997;7:231-240.
40. Ruiz-Torres A, Lozano R, Melón J, Carraro R: Age-dependent decline of in vitro migration (basal and stimulated by IGF-1 or insulin) of human vascular smooth muscle cells. J Gerontol Biol Sci 2003;58A:1074-1077.
41. Paolisso G, Tagliamonte MR, Rizzo MR, Giugliano D: Advancing age and insulin resistance: New facts about an ancient history. Eur J Clin Invest 1999;29:758-769.