메뉴 건너뛰기




Volumn 28, Issue 3, 2005, Pages 249-254

Protective effect of antioxidant ebselen (PZ51) on the cerebral cortex of stroke-prone spontaneously hypertensive rats

Author keywords

Cortical neuron; Ebselen (PZ51); Inducible nitric oxide synthase; Nitric oxide; Stroke prone spontaneously hypertensive rats

Indexed keywords

EBSELEN; MALONALDEHYDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTECTIVE AGENT;

EID: 20444496921     PISSN: 09169636     EISSN: None     Source Type: Journal    
DOI: 10.1291/hypres.28.249     Document Type: Article
Times cited : (23)

References (36)
  • 1
    • 0242609907 scopus 로고    scopus 로고
    • Tea polyphenols regulate nicotinamide adenine dinucleotide phosphate oxidase subunit expression and ameliorate angiotensin II-induced hyperpermeability in endothelial cells
    • Ying CJ, Xu JW, Ikeda K, Takahashi K, Nara Y, Yamori Y: Tea polyphenols regulate nicotinamide adenine dinucleotide phosphate oxidase subunit expression and ameliorate angiotensin II-induced hyperpermeability in endothelial cells. Hypertens Res 2003; 26: 823-828.
    • (2003) Hypertens. Res. , vol.26 , pp. 823-828
    • Ying, C.J.1    Xu, J.W.2    Ikeda, K.3    Takahashi, K.4    Nara, Y.5    Yamori, Y.6
  • 2
    • 5044221978 scopus 로고    scopus 로고
    • Increased plasma 8-isoprostane levels in hypertensive subjects: The Tsurugaya Project
    • Hozawa A, Ebihara S, Ohmori K, et al: Increased plasma 8-isoprostane levels in hypertensive subjects: the Tsurugaya Project. Hypertens Res 2004; 27: 557-561.
    • (2004) Hypertens. Res. , vol.27 , pp. 557-561
    • Hozawa, A.1    Ebihara, S.2    Ohmori, K.3
  • 3
    • 0031654663 scopus 로고    scopus 로고
    • Anti-oxidant status and lipid peroxidation in patients with essential hypertension
    • Carla R, Oliviero O, Domenico G, et al: Anti-oxidant status and lipid peroxidation in patients with essential hypertension. J Hypertens 1998; 16: 1267-1271.
    • (1998) J. Hypertens. , vol.16 , pp. 1267-1271
    • Carla, R.1    Oliviero, O.2    Domenico, G.3
  • 4
    • 0026544582 scopus 로고
    • Involvement of lipid peroxidation in CNS injury
    • Braughler JM, Hall ED: Involvement of lipid peroxidation in CNS injury. J Neurotrauma 1992; 9 (Suppl): S1-S7.
    • (1992) J. Neurotrauma , vol.9 , Issue.SUPPL.
    • Braughler, J.M.1    Hall, E.D.2
  • 5
    • 0032961289 scopus 로고    scopus 로고
    • Genetic vulnerability of cortical neurons isolated from strole-prone spontaneously hypertensive rats in hypoxia and oxygen reperfusion
    • Tagami M, Yamagata K, Ikeda K, et al: Genetic vulnerability of cortical neurons isolated from strole-prone spontaneously hypertensive rats in hypoxia and oxygen reperfusion. Hypertens Res 1999; 22: 23-29.
    • (1999) Hypertens. Res. , vol.22 , pp. 23-29
    • Tagami, M.1    Yamagata, K.2    Ikeda, K.3
  • 6
    • 0038073076 scopus 로고    scopus 로고
    • Antioxidant nutrients and hypoxia/ischemia brain injury in rodents
    • Ikeda K, Negishi H, Yamori Y: Antioxidant nutrients and hypoxia/ischemia brain injury in rodents. Toxicology 2003; 189: 55-61.
    • (2003) Toxicology , vol.189 , pp. 55-61
    • Ikeda, K.1    Negishi, H.2    Yamori, Y.3
  • 7
    • 0032995564 scopus 로고    scopus 로고
    • Implication of hypertensive rat models for primordial nutritional prevention of cardiovascular diseases
    • Yamori Y: Implication of hypertensive rat models for primordial nutritional prevention of cardiovascular diseases. Clin Exp Pharmocol Physiol 1999; 26: 568-572.
    • (1999) Clin. Exp. Pharmocol. Physiol. , vol.26 , pp. 568-572
    • Yamori, Y.1
  • 8
    • 4344634840 scopus 로고    scopus 로고
    • Assessment of oxidative stress in the spontaneously hypertensive rat brain using electron spin resonance (ESR) imaging and in vivo L-band ESR
    • Lee MC, Shouji H, Mayazaki H, et al: Assessment of oxidative stress in the spontaneously hypertensive rat brain using electron spin resonance (ESR) imaging and in vivo L-band ESR. Hypertens Res 2004; 27: 485-492.
    • (2004) Hypertens. Res. , vol.27 , pp. 485-492
    • Lee, M.C.1    Shouji, H.2    Mayazaki, H.3
  • 9
    • 0030700698 scopus 로고    scopus 로고
    • Sex differences in the abundance of endothelial nitric oxide in a model of genetic hypertension
    • McIntyre M, Hamilton CA, Rees DD, Reid JL, Dominczak AF: Sex differences in the abundance of endothelial nitric oxide in a model of genetic hypertension. Hypertension 1997; 30: 1517-1524.
    • (1997) Hypertension , vol.30 , pp. 1517-1524
    • McIntyre, M.1    Hamilton, C.A.2    Rees, D.D.3    Reid, J.L.4    Dominczak, A.F.5
  • 10
    • 0031010677 scopus 로고    scopus 로고
    • Acceleration of hypertensive cerebral injury by the inhibition of xanthine-xanthine oxidase system in stroke-prone spontaneously hypertensive rats
    • Maenishi O, Ito H, Suzuki T: Acceleration of hypertensive cerebral injury by the inhibition of xanthine-xanthine oxidase system in stroke-prone spontaneously hypertensive rats. Clin Exp Hypertens 1997; 19: 461-477.
    • (1997) Clin. Exp. Hypertens. , vol.19 , pp. 461-477
    • Maenishi, O.1    Ito, H.2    Suzuki, T.3
  • 11
    • 0028180046 scopus 로고
    • Preferential inhibition of inducible nitric oxide synthase by ebselen
    • Hattori R, Inoue R, Sase K, et al: Preferential inhibition of inducible nitric oxide synthase by ebselen. Eur J Pharmacol 1994; 267: R1-R2.
    • (1994) Eur. J. Pharmacol. , vol.267
    • Hattori, R.1    Inoue, R.2    Sase, K.3
  • 12
    • 0030034735 scopus 로고    scopus 로고
    • The reaction of ebselen with peroxynitrite
    • Masumoto H, Sies H: The reaction of ebselen with peroxynitrite. Chem Res Toxicol 1996; 9: 262-267.
    • (1996) Chem. Res. Toxicol. , vol.9 , pp. 262-267
    • Masumoto, H.1    Sies, H.2
  • 13
    • 0021814689 scopus 로고
    • A novel biologically active selenoorganic compound, IV protective glutathione-dependent effect of PZ51 (ebselen) against ADP-Fe induced lipid peroxidation in isolated hepatocytes
    • Muller A, Gabriel H, Sies H: A novel biologically active selenoorganic compound, IV protective glutathione-dependent effect of PZ51 (ebselen) against ADP-Fe induced lipid peroxidation in isolated hepatocytes. Biochem Pharmacol 1985; 34: 2691-2694.
    • (1985) Biochem. Pharmacol. , vol.34 , pp. 2691-2694
    • Muller, A.1    Gabriel, H.2    Sies, H.3
  • 14
    • 0021814689 scopus 로고
    • Anovel biologically active seleno-organic compound V: Inhibition by PZ51 (ebselen) of rat peritoneal neutrophil lipoxygenase
    • Safayhi H, Tiegs G, Wendel A: Anovel biologically active seleno-organic compound V: inhibition by PZ51 (ebselen) of rat peritoneal neutrophil lipoxygenase. Biochem Pharmacol 1985; 34: 2691-2694.
    • (1985) Biochem. Pharmacol. , vol.34 , pp. 2691-2694
    • Safayhi, H.1    Tiegs, G.2    Wendel, A.3
  • 15
    • 0031963836 scopus 로고    scopus 로고
    • Ebselen in acute ischemic stroke: A Placebo-controlled, double-blind clinical trial
    • for the Ebselen Study Group
    • Yamaguchi T, Sano K, Takakura K, et al, for the Ebselen Study Group: Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Stroke 1998; 29: 12-17.
    • (1998) Stroke , vol.29 , pp. 12-17
    • Yamaguchi, T.1    Sano, K.2    Takakura, K.3
  • 16
    • 0042122368 scopus 로고    scopus 로고
    • Ebselen, a seleno-organic antioxidant, is neuroprotective after embolic strokes in rabbits: Synergism with low-dose tissue plasminogen activator
    • Pau AL, Justin AZ: Ebselen, a seleno-organic antioxidant, is neuroprotective after embolic strokes in rabbits: synergism with low-dose tissue plasminogen activator. Stroke 2003; 34: 2013-2018.
    • (2003) Stroke , vol.34 , pp. 2013-2018
    • Pau, A.L.1    Justin, A.Z.2
  • 17
    • 0028819079 scopus 로고
    • The neuroprotective efficacy of ebselen (a glutathione peroxidase mimic) on brain damage induced by transient focal cerebral ischaemia in the rat
    • Dawson DA, Masayasu H, Graham DI, Macrae IM: The neuroprotective efficacy of ebselen (a glutathione peroxidase mimic) on brain damage induced by transient focal cerebral ischaemia in the rat. Neurosci Lett 1995; 185: 65-69.
    • (1995) Neurosci. Lett. , vol.185 , pp. 65-69
    • Dawson, D.A.1    Masayasu, H.2    Graham, D.I.3    Macrae, I.M.4
  • 18
    • 0030734080 scopus 로고    scopus 로고
    • Neuroprotective efficacy of ebselen, an antioxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral artery occlusion
    • Takasago T, Peters EE, Graham DI, Masayasu H, Macrae IM: Neuroprotective efficacy of ebselen, an antioxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral artery occlusion. Br J Pharmacol 1997; 122: 1251-1256.
    • (1997) Br. J. Pharmacol. , vol.122 , pp. 1251-1256
    • Takasago, T.1    Peters, E.E.2    Graham, D.I.3    Masayasu, H.4    Macrae, I.M.5
  • 19
    • 0034884323 scopus 로고    scopus 로고
    • Ebselen reduces cytochrome c release from mitochondria and subsequent DNA fragmentation after transient focal cerebral ischemia in mice
    • Namura S, Nagata I, Takami S, Masayasu H, Kikuchi H: Ebselen reduces cytochrome c release from mitochondria and subsequent DNA fragmentation after transient focal cerebral ischemia in mice. Stroke 2001; 32: 1906-1911.
    • (2001) Stroke , vol.32 , pp. 1906-1911
    • Namura, S.1    Nagata, I.2    Takami, S.3    Masayasu, H.4    Kikuchi, H.5
  • 20
    • 0028916077 scopus 로고
    • Lipopolysaccharide-induce changes in plasma nitrite and nitrate concentrations in rat and mice: Pharmacological evaluation of nitric oxide synthase inhibitors
    • Tracey WR, Tse J, Carter G: Lipopolysaccharide-induce changes in plasma nitrite and nitrate concentrations in rat and mice: pharmacological evaluation of nitric oxide synthase inhibitors. J Pharmacol Exp Ther 1995; 272: 1011-1015.
    • (1995) J. Pharmacol. Exp. Ther. , vol.272 , pp. 1011-1015
    • Tracey, W.R.1    Tse, J.2    Carter, G.3
  • 21
    • 0037135121 scopus 로고    scopus 로고
    • Effect of spiramine T on antioxidant enzymatic activities and nitric oxide production in cerebral ischemia-reperfusion gerbils
    • Ling L, Yue MS, Xiao SY, et al: Effect of spiramine T on antioxidant enzymatic activities and nitric oxide production in cerebral ischemia-reperfusion gerbils. Brain Res 2002; 944: 205-209.
    • (2002) Brain Res. , vol.944 , pp. 205-209
    • Ling, L.1    Yue, M.S.2    Xiao, S.Y.3
  • 22
    • 0037897557 scopus 로고    scopus 로고
    • The antioxidant EPC-K1 ameliorates brain injury by inhibiting lipid peroxidation in a rat model of transient focal cerebral ischaemia
    • Kato N, Yanaka K, Nagase S, Hirayama A, Nose T: The antioxidant EPC-K1 ameliorates brain injury by inhibiting lipid peroxidation in a rat model of transient focal cerebral ischaemia. Acta Neurochir 2003; 145: 489-493.
    • (2003) Acta Neurochir. , vol.145 , pp. 489-493
    • Kato, N.1    Yanaka, K.2    Nagase, S.3    Hirayama, A.4    Nose, T.5
  • 23
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 24
    • 0029990439 scopus 로고    scopus 로고
    • Astrocytes protect neurons from hydrogen peroxide toxicity
    • Desagher S, Glowinski J, Premont J: Astrocytes protect neurons from hydrogen peroxide toxicity. J Neurosci 1996; 16: 1553-2562.
    • (1996) J. Neurosci. , vol.16 , pp. 1553-2562
    • Desagher, S.1    Glowinski, J.2    Premont, J.3
  • 25
    • 0023601670 scopus 로고
    • Inhibition of superoxide anion production in guinea pig polymorphonuclear leukocytes by a seleno-organic compound, ebselen
    • Ichikawa S, Omura K, Katayama T, et al: Inhibition of superoxide anion production in guinea pig polymorphonuclear leukocytes by a seleno-organic compound, ebselen. J Pharmacobiodyn 1987; 10: 595-597.
    • (1987) J. Pharmacobiodyn. , vol.10 , pp. 595-597
    • Ichikawa, S.1    Omura, K.2    Katayama, T.3
  • 26
    • 0033021938 scopus 로고    scopus 로고
    • Superoxide anion production is increased in a model of genetic hypertension: Role of the endothelium
    • Kerr S, Brosnan MJ, Mcintyrre M, et al: Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium. Hypertension 1999; 33: 1353-1358.
    • (1999) Hypertension , vol.33 , pp. 1353-1358
    • Kerr, S.1    Brosnan, M.J.2    Mcintyrre, M.3
  • 27
    • 1642422232 scopus 로고    scopus 로고
    • Activation of protein kinase C and nicotinamide adenine dinucleotide phosphate oxidase in leukocytes of spontaneously hypertensive rats
    • Maeda K, Yasunari K, Sato EF, Yoshikawa J, Inoue M: Activation of protein kinase C and nicotinamide adenine dinucleotide phosphate oxidase in leukocytes of spontaneously hypertensive rats. Hypertens Res 2003; 26: 999-1006.
    • (2003) Hypertens. Res. , vol.26 , pp. 999-1006
    • Maeda, K.1    Yasunari, K.2    Sato, E.F.3    Yoshikawa, J.4    Inoue, M.5
  • 28
    • 0036924784 scopus 로고    scopus 로고
    • Measurement of oxidative stress in stroke-prone spontaneously hypertensive rat brain using in vivo electron spin resonance spectroscopy
    • Miyazaki H, Shoji H, Lee MC: Measurement of oxidative stress in stroke-prone spontaneously hypertensive rat brain using in vivo electron spin resonance spectroscopy. Redox Rep 2002; 7: 260-265.
    • (2002) Redox. Rep. , vol.7 , pp. 260-265
    • Miyazaki, H.1    Shoji, H.2    Lee, M.C.3
  • 29
    • 0027787470 scopus 로고
    • A comparative study on lipid peroxidation in cerebral cortex of stroke-prone spontaneously hypertensive and normotensive rats
    • Ito H, Torii M, Suzuki T: A comparative study on lipid peroxidation in cerebral cortex of stroke-prone spontaneously hypertensive and normotensive rats. Int J Biochem 1993; 25: 1801-1805.
    • (1993) Int. J. Biochem. , vol.25 , pp. 1801-1805
    • Ito, H.1    Torii, M.2    Suzuki, T.3
  • 30
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H, Ohishi N, Yagi K: Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 15: 351-358.
    • (1979) Anal. Biochem. , vol.15 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 31
    • 0017065248 scopus 로고
    • A simple fluorometric assay for lipoperoxide in blood plasm
    • Yagi K: A simple fluorometric assay for lipoperoxide in blood plasm. Biochem Med 1976; 15: 212-216.
    • (1976) Biochem. Med. , vol.15 , pp. 212-216
    • Yagi, K.1
  • 32
    • 0032521138 scopus 로고    scopus 로고
    • Oxidative stress developed during the reperfusion of ischemic myocardium induces apoptosis
    • Maulik N, Yoshida T, Das DK: Oxidative stress developed during the reperfusion of ischemic myocardium induces apoptosis. Free Radical Biol 1998; 24: 869-875.
    • (1998) Free Radical Biol. , vol.24 , pp. 869-875
    • Maulik, N.1    Yoshida, T.2    Das, D.K.3
  • 33
    • 0027975453 scopus 로고
    • Nitric oxide: A physiologic messenger molecule
    • Bredt D, Snyder SA: Nitric oxide: a physiologic messenger molecule. Annu Rev Biochem 1994; 63: 175-195.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 175-195
    • Bredt, D.1    Snyder, S.A.2
  • 34
    • 0034889199 scopus 로고    scopus 로고
    • Oxidative inactivation of nitric oxide and endothelial dysfunction in stroke-prone spontaneous hypertensive rats
    • Ma XL, Gao F, Nelson AH, et al: Oxidative inactivation of nitric oxide and endothelial dysfunction in stroke-prone spontaneous hypertensive rats. J Pharmacol Exp Ther 2001; 298: 879-885.
    • (2001) J. Pharmacol. Exp. Ther. , vol.298 , pp. 879-885
    • Ma, X.L.1    Gao, F.2    Nelson, A.H.3
  • 35
    • 0029797162 scopus 로고    scopus 로고
    • Effect of ebselen on bovine and rat nitric oxide synthase activity is modified by thiols
    • Hattori R, Yui Y, Shinoda E, et al: Effect of ebselen on bovine and rat nitric oxide synthase activity is modified by thiols. Jpn J Pharmacol 1996; 72: 191-193.
    • (1996) Jpn. J. Pharmacol. , vol.72 , pp. 191-193
    • Hattori, R.1    Yui, Y.2    Shinoda, E.3
  • 36
    • 2342525162 scopus 로고    scopus 로고
    • Amlodipine and carvedilol prevent cytotoxicity in cortical neurons isolated from stroke-prone spontaneously hypertensive rats
    • Yamagata K, Ichinose S, Tagami M: Amlodipine and carvedilol prevent cytotoxicity in cortical neurons isolated from stroke-prone spontaneously hypertensive rats. Hypertens Res 2004; 27: 271-282.
    • (2004) Hypertens. Res. , vol.27 , pp. 271-282
    • Yamagata, K.1    Ichinose, S.2    Tagami, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.