Sex differences in the abundance of endothelial nitric oxide in a model of genetic hypertension

Hypertension

Volumn 30, Issue 6, 1997, Pages 1517-1524

  McIntyre, Martin ^c   Hamilton, Carlene A ^c   Rees, Daryl D ^a,b   Reid, John L ^c   Dominiczak, Anna F ^a  

^a WESTERN INFIRMARY   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NONE

Author keywords

Nitric oxide; Nitric oxide synthase; Rats, stroke prone spontaneously hypertensive; Superoxide anion; Superoxide dismutase

Indexed keywords

NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SUPEROXIDE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ESSENTIAL HYPERTENSION; FEMALE; GENDER; HEREDITARY HYPERTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; STRAIN DIFFERENCE; STROKE;

EID: 0030700698     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.30.6.1517     Document Type: Article

References (50)

1. Tunstall-Pedoe H, Morrison C, Woodward M, Fitzpatrick B, Watt G. Sex differences in myocardial infarction and coronary deaths in the Scottish MONICA population of Glasgow 1985-1991: presentation, diagnosis, treatment, and 28-day case fatality of 3991 events in men and 1551 events in women. Circulation. 1996;93:1981-1992.
2. Iams SG, Wexler BC. Inhibition of development of spontaneous hypertension in SH rats by gonadectomy or estradiol. J Lab Clin Med. 1979;10:608-616.
3. Hayashi T, Fukuto JM, Ignarro LJ, Chaudhuri G. Gender differences in atherosclerosis: possible role of nitric oxide. J Cardiovasc Pharmacol. 1995;26:792-802.
4. Vallance P, Collier J, Moncada S. Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man. Lancet. 1989;2:997-1000.
5. Cooke JP, Tsao PS. Is nitric oxide an endogenous antiatherogenic molecule? Arterioscler Thromb. 1994;14:653-655.
6. Chowienczyk PJ, Watts GF, Cockcroft JR, Brett SE, Ritter JM. Sex differences in endothelial function in normal and hypercholesteroiaemic subjects. Lancet. 1994;344:305-306.
7. Kauser K, Rubanyi GM. Gender differences in endothelial dysfunction in the aorta of spontaneously hypertensive rats. Hypertension. 1995;25:517-523.
8. Tanase H, Suzuki Y, Ooshima A, Yamori Y, Okamoto K. Genetic analysis of blood pressure in spontaneously hypertensive rats. Jpn Circ. J. 1970;34:1197-1202.
9. Ganten U, Schroder G, Witt M, Zimmerman F, Ganten D, Stock G. Sexual dimorphism of blood pressure in spontaneously hypertensive rats: effects of anti-androgen treatment. Hypertension. 1989;7:721-726.
10. Turner ME, Johnson ML, Ely DL. Separate sex-influenced and genetic components in spontaneously hypertensive rat hypertension. Hypertension. 1991;17:1097-1103.
11. The Writing Group for the PEPI Trial. Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in post-menopausal women: the Post-menopausal Estrogen/progestin Interventions (PEPI) Trial. JAMA. 1995;273:199-208.
12. Colditz GA, Willen WC, Stampfer MJ, Rosner B, Speizer FE, Hennekens CH. Menopause and the risk of coronary heart disease in women. N Engl J Med. 1987;316:1105-1110.
13. Haarbo J, Leth-Espensen P, Slender S, Christiansen C. Estrogen monotherapy and combined estrogen-progestogen replacement therapy attenuate aortic accumulation of cholesterol in ovariectomized cholesterol-fed rabbits. J Clin Invest. 1991;87:1274-1279.
14. Gilligan DM, Badar DA, Panza JA, Quyyumi AA, Canon RO III. Acute vascular effects of estrogen in post menopausal women. Circulation. 1994;90:786-791.
15. Williams SP, Shackelford DP, Iams SG, Mustafa SJ. Endothelium-dependent relaxation in estrogen-treated spontaneously hypertensive rats. Eur J Pharmacol. 1988;145:205-207.
16. Ahokas RA, Mercer BM, Sibai BM. Enhanced endothelium-derived relaxing factor activity in pregnant, spontaneously hypertensive rats. J Obstet Gynaecol. 1991;165:801-807.
17. Gisclard V, Miller VM, Vanhoutte PM. Effect of 17β-estradiol on endothelium-dependent responses in the rabbit. J Pharmacol Exp Ther. 1988;244:19-22.
18. Gisclard V, Flavahan NA, Vanhoutte PM. Alpha adrenergic responses of blood vessels of rabbit after ovariectomy and administration of 17β-estradiol. J. Pharmacol. Exp. Ther. 1987;240:466-470.
19. Miller VM, Vanhoutte PM. 17β-estradiol augments endothelium-dependent contractions to arachadonic acid in rabbit aorta. Am J Physiol. 1990;258:R1502-R1507.
20. Stallone JN, Crofton JT, Share L. Sexual dimorphism in vasopressin-induced contraction of rat aorta. Am J Physiol. 1991;260:H453-H458.
21. Jiang C, Sarrel PM, Poole-Wilson PA, Collins P. Acute effects of 17β-estradiol on rabbit coronary artery contractile responses to endothelin I. Am J Physiol. 1992;263:H271-H275.
22. Venema RC, Nishida K, Alexander RW, Harrison DG Murphy TJ. Organisation of the bovine gene encoding the endothelial nitric oxide synthase. Biochem Biophys Acta. 1994;3:413-420.
23. Hishikawa K, Nakaki T, Marumo T, Suzuki H, Kato R, Saruta T. Up-regulation of nitric oxide synthase by estradiol in human aortic endothelial cells. FEBS Lett. 1995;360:291-293.
24. Geotz RM, Morano I, Calvoni T, Studer T, Holtz J. Increased expression of endothelial constitutive nitric oxide synthase in rat aorta during pregnancy. Biochem Biophys Res Commun. 1994;205:905-910.
25. Panza JA, Quyyumi AA, Brush JE Jr, Epstein SE. Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension. N Engl J Med. 1990;323:22-27.
26. G-monomethyl-L-arginine in patients with hypertension: the nitric oxide dilator mechanism appears abnormal. J Hypertens. 1992;10:1025-1031.
27. Cockcroft JR, Chowienczyk PJ, Benjamin N, Ritter JM. Preserved endothelium-dependent vasodilatation in patients with essential hypertension. N Engl J Med. 1994;330:1036-1040.
28. Malinski T, Kapturczak M, Dayharsh J, Bohr DF. Nitric oxide synthase activity in genetic hypertension. Biochem Biophys Res Comm. 1993;194:654-658.
29. Rees DD, Ben-Ishay D, Moncada S. Nitric oxide and the regulation of blood pressure in hypertension-prone and hypertension-resistant Sabra rat. Hypertension. 1996;28:367-371.
30. Luscher TF, Vanhoutte PM. Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat. Hypertension. 1986;8:344-348.
31. Rubanyi GM, Vanhoutte PM. Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. Am J Physiol. 1986; 250(Heart Circ Physiol.):HS22-H827.
32. Liu S, Beckman JS, Ku DD. Peroxynitrite, a product of superoxide and nitric oxide, produces coronary vasorelaxation in dogs. J Pharmacol Exp Ther. 1994;268:1114-1121.
33. Szaho C, Zingarelli B, O'Connor M, Salzman AL. DNA strand breakage, activation of poly (ADP-ribose) synthetase, and macrophages and smooth muscle cells exposed to peroxynitrite. Proc Natl Acad Sci U S A. 1996;93:1753-1758.
34. Grunfeld S, Hamilton CA, Mesaros S, McClain SW, Dominiczak AF, Bohr DF, Malinski T. Role of superoxide in the depressed nitric oxide production by the endothelium of genetically hypertensive rats. Hypertension. 1995;26:854-857.
35. Hamilton CA, Berg G, McIntyre M, McPhaden AR, Reid JL, Dominiczak AF. Effects of nitric oxide and superoxide on relaxation in human artery and vein. Atherosclerosis. 1997;133:77-86.
36. Nakazono K, Watanabe N, Matsuno K, Sasaki J, Sato T, Inoue M. Does superoxide underlie the pathogenesis of hypertension? Proc Natl Acad Sci U S A. 1991;88:10045-10048.
37. Dominiczak AF, McLaren Y, Kusel J, Bell D, Goodfreind TL, Bohr DF, Reid JL. Lateral diffusion and fatty acid composition in vascular smooth muscle membrane from stroke-prone spontaneously hypertensive rats. Am J Hypertens. 1993;6:1003-1008.
38. Evans AL, Brown W, Kenyon CJ, Maxted KJ, Smith DC. Improved system for measuring systolic blood pressure in the conscious rat. Med Biol Eng Comput. 1994;32:101-102.
39. Rees DD, Cunha FQ, Assreuy J, Herman AG, Moncada S. Sequential induction of nitric oxide synthase by Corynebacterium parvum in different organs of the mouse. Br J Pharmacol. 1995;114:689-693.
40. Rees DD, Palmer RJM, Schultz R, Hodson HF, Moncada S. Characterisation of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br J Pharmacol. 1990;101:746-752.
41. 15N] nitrate in biological fluids. Anal Biochem. 1982;126:131-138.
42. Forte P, Copland M, Smith LM, Milne E, Sutherland J, Benjamin N. Basal nitric oxide synthesis in essential hypertension. Lancet. 1997;349:837-842.
43. Hayashi T, Fukuto JM, Ignarro LJ, Chaudhuri G. Basal release of nitric oxide from aortic rings is greater in female rabbits than in males rabbits: implications for atherosclerosis. Proc Natl Acad Sci USA. 1992;89:11259-11263.
44. Mian KB, Martin W. Differential sensitivity of basal and acetylcholine-stimulated activity of nitric oxide to destruction by superoxide anion in rat aorta. Br J Pharmacol. 1995;115:993-1000.
45. Kauser K, Rubanyi GM. Gender differences in bioassayable endothelium-derived nitric oxide from isolated aortae. Am J Physiol. 1994;267(Heart Circ Physiol.36):H2311-H2317.
46. Harrison DG, Bates JN. The nitrovasodilators: new ideas about old drugs. Circulation. 1993;87:1461-1467.
47. Schini VB, Kim ND, Vanhoutte PM. The basal and stimulated release of EDRF inhibits the contractions evoked by endothelin-1 and endothelin-3 in aortae of normotensive and spontaneously hypertensive rats. J Cardiovasc Pharmacol. 1991;17:S267-S271.
48. Arnal JF, Clamens S, Pechet C, Negre-Salvayre A, Allera C, Girolami J-P, Salvayre R, Bayard F. Ethinylestradiol does not enhance the expression of nitric oxide synthase in bovine endothelial cells but increases the release of bioactive nitric oxide by inhibiting superoxide anion production. Proc Natl Acad Sci U S A. 1996;93:4108-4113.
49. Mügge A, Elwell JH, Peterson TE, Hofmeyer TG, Heistad DD, Harrison DG. Chronic treatment with polyethylene-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxations in cholesterol-fed rabbits. Circ Res. 1991;69:1293-1300.
50. Laursen JB, Rajagopalan S, Galis Z, Tarpey M, Freeman BA, Harrison DG. Role, of superoxide in angiotensin II-induced but not catecholamine-induced hypertension. Circulation. 1997;95:588-593.