Genetic vulnerability of cortical neurons isolated from stroke-prone spontaneously hypertensive rats in hypoxia and oxygen reperfusion

Hypertension Research - Clinical and Experimental

Volumn 22, Issue 1, 1999, Pages 23-29

  Tagami, Motoki ^a   Yamagata, Kazuo ^b   Ikeda, Katsumi ^c   Fujino, Hideaki ^a   Nara, Yasuo ^b   Nakagawa, Kiyoshi ^c   Kubota, Akiyoshi ^a   Numano, Fujio ^d   Yamori, Yukio ^c  

^a Sanraku Hospital   (Japan)

^b UNIVERSITY OF EAST ASIA   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Antioxidant; Apoptosis; Hypoxia; Insulin like growth factor; Oxygen radical

Indexed keywords

FREE RADICAL; GROWTH FACTOR; IDEBENONE; N METHYL DEXTRO ASPARTIC ACID; NEUROPROTECTIVE AGENT; NEUROTOXIN; NILVADIPINE; NITRIC OXIDE; OXYGEN RADICAL; PROTEIN P53; SOMATOMEDIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN CELL; CELL DAMAGE; CELL DEATH; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; FETUS; GENETIC SUSCEPTIBILITY; HYPERTENSION; HYPOXIA; NONHUMAN; RAT; REPERFUSION; SPONTANEOUSLY HYPERTENSIVE RAT; STROKE;

EID: 0032961289     PISSN: 09169636     EISSN: None     Source Type: Journal    
DOI: 10.1291/hypres.22.23     Document Type: Article

References (38)

1. Okamoto K, Yamori Y, Nagaoka A: Establishment of the stroke-prone spontaneously hypertensive rat (SHR). Circ Res 1974; 34/35 (Suppl I): 143-153.
2. Yamori Y, Horie R: Developmental course of hypertension and regional cerebral blood flow in stroke-prone spontaneously hypertensive rats. Stroke 1977; 8:456-461.
3. Tagami M, Nara Y, Kubota A, et al: Ultrastructural characteristic of occluded perforating arteries in stroke-prone spontaneously hypertensive rats. Stroke 1987; 18: 733-740.
4. Kirino T: Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res 1982; 239: 57-69.
5. Kirino T, Tamura A, Sano K: Delayed neuronal death in the rat hippocampus following transient forebrain ischemia. Acta Neuropathol (Berl) 1984; 64: 139-147.
6. Petito CK, Pulsinelli WA: Delayed neuronal recovery and neuronal death in rat hippocampus following severe cerebral ischemia: possible relationship to abnormalities in neuronal processes. J Cereb Blood Flow Metab 1984; 4: 194-205.
7. MacManus JP, Buchan AM, Hill IE, et al: Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain. Neurosci Lett 1993; 24: 89-92.
8. Ferrer I, Tortosa A, Macaya A, et al: Evidence of nuclear DNA fragmentation following hypoxia-ischemia in the infarct brain, and transient forebrain ischemia in the adult gerbil. Brain Pathol 1994; 4: 115-122.
9. Choi DW: Glutamate neurotoxicity and disease of the nervous system. Neuron 1988; 1: 623-634.
10. Rothmann SM, Olney JW: Glutamate and the pathophysiology of hypoxic-ischemia brain damage. Ann Neurol 1986; 19: 105-111.
11. Schubert D, Kimura H, Maher P: Growth factors and vitamin E modify neuronal glutamate toxicity. Proc Natl Acad Sci USA 1994; 89: 8264-8267.
12. Amano S, Ohashi M, Kirihara M, et al: α-Tocophelol protects against radical-induced injury in cultured neurons. Neurosci Lett 1994; 170: 55-58.
13. Tagami M, Yamagata K, Nara Y, et al: Insulin-like growth factors prevent apoptosis in cortical neurons isolated from stroke-prone spontaneously hypertensive rats. Lab Invest 1997; 76: 603-612.
14. Tagami M, Yamagata K, Ikeda K, et al: Vitamin E prevents apoptosis in cortical neurons during hypoxia and oxygen reperfusion. Lab Invest 1998; 78: 1415-1429.
15. Kerr JFR, Wyllie AH, Currie AR: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26: 239-245.
16. Rothmann SM, Olney JW: Glutamate and the pathophysiology of hypoxic-ischemia brain damage. Ann Neurol 1986; 19: 105-111.
17. Bolli R: Oxygen-derived free radicals and myocardial reperfusion injury: an overview. Cardiovasc Drugs Ther 1991; 5: 249-268.
18. Kukreja RC, Hess ML: The oxygen free radical system: from equations through membrane-protein interactions to cardiovascular injury and protection. Cardiovasc Res 1992; 26: 641-655.
19. McCord JM: Oxygen-derived free radicals in postischemic tissue injury. N Engl J Med 1985; 312: 159-163.
20. Zweier JL: Measurement of superoxide-derived free radicals in the reperfused heart. J Biol Chem 1988; 263: 1352-1357.
21. Thompson-Gorman SL, Zweier JL: Evaluation of the role of xanthine oxidase in myocardial reperfusion injury. J Biol Chem 1990; 265: 6656-6663.
22. Halliwell B, Gutteridge JMC: Free Radicals, in Biology and Medicine, ed. 2., Oxford, Clarendon Press, 1989, pp 1-81.
23. Orrenius S, Nicotera P: Biochemical mechanisms of oxidative liver cell injury. Bull Eur Physiopathol Respir 1987; 23: 291-295.
24. Malorni W, Rivabene R, Santini MT, et al: Down-modulation of CD4 antigen during programmed cell death in U937 cells. FEBS Lett 1993; 336: 335-339.
25. Kane DJ, Sarafian TA, Anton R, et al: Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science 1993; 262: 1274-1277.
26. Dypbukt JM, Ankarcrona M, Burkitt M, et al: Different prooxidant levels stimulate growth, trigger apoptosis. or produce necrosis of insulin-secreting RINm5F cells. J Biol Chem 1994; 269: 30553-30560.
27. Miyamoto M, Murphy TH, Schnaar RL, et al: Antioxidants protect against glutamate-induced cytotoxicity in a neuronal cell line. J Phannacol Exp Ther 1989; 250: 1132-1140.
28. Murakami M, Zs.-Nagy I: Superoxide radical scavenging activity of idebenone in vitro studied by ESR spin trapping method and direct ESR measurement at liquid nitrogen temperature. Arch Gerontol Geriatr 1990; 11: 199-214.
29. 53-dependent and independent pathways. Nature 1993; 362: 849-852.
30. 53 tumor suppression. Cell 1993; 75: 817-825.
31. Ankarcrona M, Dypbukt JM, Brune B, et al: Interleukin-1-induced nitric oxide production activates apoptosis in pancreatic RINm5F cells. Exp Cell Res 1994; 213: 172-177.
32. 53 activity by DNA-damaging agents and growth arrest. Mol Cell Biol 1993; 13: 4242-4250.
33. 53 status. Mol Cell Biol 1994; 14: 6264-6277.
34. 53. Nature 1995; 337: 646-649.
35. Nickerson T, Huynh H, Pollak M: Insulin-like growth factor binding protein-3 induces apoptosis in MCF7 breast cancer cells. Biochem Biophys Res Commun 1997; 237: 690-693.
36. Yao R, Cooper GM: Requirement for phosphatidyl inositol-3 kinase in the prevention of apoptosis by nerve growth factor. Science 1995; 267: 2003-2005.
37. Kuwaki T, Satoh H, Ono T, et al: Nilvadipine attenuates ischemic degradation of gerbil brain cytoskeletal proteins. Stroke 1989; 20: 78-83.
38. Kawamura S, Shirasawa M, Fukasawa H, et al: Attenuated neuropathology by nilvadipine after middle cerebral artery occlusion in rats. Stroke 1991; 22: 51-55.