High level of endothelial cell-specific gene expression by a combination of the 5′ flanking region and the 5′ half of the first intron of the VE-cadherin gene

Blood

Volumn 105, Issue 12, 2005, Pages 4657-4663

  Hisatsune, Hiroshi ^b   Matsumura, Kazuyoshi ^b   Ogawa, Minetaro ^b   Uemura, Akiyoshi ^b   Kondo, Nobuyuki ^b   Yamashita, Jun K ^b   Katsuta, Hideto ^b   Nishikawa, Satomi ^b   Chiba, Tsutomu ^b   Nishikawa, Shin Ichi ^a  

^a Center for Developmental Biology   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CADHERIN; GENOMIC DNA; GREEN FLUORESCENT PROTEIN; LUCIFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL MANIPULATION; DNA FLANKING REGION; EMBRYO; EMBRYONIC STEM CELL; ENDOTHELIUM CELL; GENE EXPRESSION; GENE SEQUENCE; HEMATOPOIETIC CELL; INTRON; MOUSE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; TRANSGENIC MOUSE;

EID: 20444406464     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-09-3554     Document Type: Article

References (24)

1. Hirashima M, Kataoka H, Nishikawa S, Matsuyoshi N. Maturation of embryonic stem cells into endothelial cells in an in vitro model of vasculogenesis. Blood. 1999;93:1253-1263.
2. Nishikawa SI, Nishikawa S, Kawamoto H, et al. In vitro generation of lymphohematopoietic cells from endothelial cells purified from murine embryos. Immunity. 1998;8:761-769
3. Burdsal CA, Damsky CH, Pedersen RA. The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak. Development. 1993;118:829-844.
4. Li M, Pevny L, Lovell-Badge R, Smith A, Generation of purified neural precursors from embryonic stem cells by lineage selection. Curr Biol. 1998;8: 971-974
5. Pan J, McEver RP. Characterization of the promoter for the human P-selectin gene. J Biol Chem. 1993;268:22600-22608.
6. Ozaki K, Yoshida T, Ide H, et al. Use of von Willebrand factor promoter to transduce suicidal gene to human endothelial cells, HUVEC. Hum Gene Ther. 1996;7:1483-1490.
7. Harats D, Kurihara H, Belloni P, et al. Targeting gene expression to the vascular wall in transgenic mice using the murine preproendothelin-1 promoter. J Clin Invest. 1995;95:1335-1344.
8. Cowan PJ, Shinkel TA, Witort EJ, Barlow H, Pearse MJ, d'Apice AJ, Targeting gene expression to endothelial cells in transgenic mice using the human intercellular adhesion molecule 2 promoter. Transplantation. 1996;62:155-160.
9. Almendro N, Bellon T, Rius C, et al. Cloning of the human platelet endothelial cell adhesion molecule-1 promoter and its tissue-specific expression: structural and functional characterization. J Immunol. 1996;157:5411-5421.
10. Korhonen J, Lahtinen I, Halmekyto M, et al. Endothelial-specific gene expression directed by the tie gene promoter in vivo. Blood. 1995;86:1828-1835.
11. Hirai H, Ogawa M, Suzuki N, et al. Hemogenic and nonhemogenic endothelium can be distinguished by the activity of fetal liver kinase (Flk)-1 promoter/enhancer during mouse embryogenesis. Blood. 2003;101:886-893.
12. Lampugnani MG, Resnati M, Raiteri M, et al. A novel endothelial-specific membrane protein is a marker of cell-cell contacts. J Cell Biol. 1992;118: 1511-1522.
13. Gory S, Vernet M, Laurent M, Dejana E, Dalmon J, Huber P. The vascular endothelial-cadherin promoter directs endothelial-specific expression in transgenic mice. Blood. 1999;93:184-192.
14. Kataoka H, Takakura N, Nishikawa S, et al. Expressions of PDGF receptor alpha, c-Kit and Flk1 genes clustering in mouse chromosome 5 define distinct subsets of nascent mesodermal cells. Dev Growth Differ. 1997;39:729-740.
15. Matsuyoshi N, Toda K, Horiguchi Y, et al. In vivo evidence of the critical role of cadherin-5 in murine vascular integrity. Proc Assoc Am Physicians. 1997;109:362-371.
16. Huber P, Dalmon J, Engiles J, et al. Genomic structure and chromosomal mapping of the mouse VE-cadherin gene (CdhS). Genomics. 1996;32:21-28.
17. Niwa H, Miyazaki J, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet. 2000;24:372-376.
18. Nakano T, Kodama H, Honjo T. Generation of lymphohematopoietic cells from embryonic stem cells in culture. Science. 1994;265:1098-1101.
19. Ogawa M, Matsuzaki Y, Nishikawa S, et al. Expression and function of c-kit in hemopoietic progenitor cells. J Exp Med. 1991;174:63-71.
20. Onodera K, Takahashi S, Nishimura S, et al. GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis. Proc Natl Acad Sci USA. 1997;94:4487-4492.
21. Jorcyk CL, Garrett LJ, Maroulakou IG, Watson DK, Green JE. Multiple regulatory regions control the expression of Ets-1 in the developing mouse: vascular expression conferred by intron I. Cell Mol Biol (Noisy-le-grand). 1997;43:211-225.
22. Seshasayee D, Geiger JN, Gaines P, Wojchowski DM. Intron 1 elements promote erythroid-specific GATA-1 gene expression. J Biol Chem. 2000;275: 22969-22977.
23. Sanada T, Park MJ, Araki A, Gotoh M, Izutsu Y, Maeno M. A BMP-4-dependent transcriptional control element in the 5′ flanking region of Xenopus SCL gene. Biochem Biophys Res Commun. 2003;310:1160-1167.
24. Kappel A, Ronicke V, Damert A, Flamme I, Risau W, Breier G. Identification of vascular endothelial growth factor (VEGF) receptor-2 (Flk-1) promoter/enhancer sequences sufficient for angioblast and endothelial cell-specific transcription in transgenic mice. Blood. 1999;93: 4284-4292.