Synthesis and characterization of a novel retinylamine analog inhibitor of constitutively active rhodopsin mutants found in patients with autosomal dominant retinitis pigmentosa

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 25, 1997, Pages 13559-13564

  Yang, Tong ^a   Snider, Barry B ^a   Oprian, Daniel D ^a  

^a BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

11 CIS RETINAL; RETINYLAMINE DERIVATIVE; RHODOPSIN; RHODOPSIN INHIBITOR; RHODOPSIN KINASE; TRANSDUCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOSOMAL DOMINANT DISORDER; ENZYME ACTIVE SITE; ENZYME PHOSPHORYLATION; ILLUMINATION; NONHUMAN; PRIORITY JOURNAL; RETINA DEGENERATION; RETINITIS PIGMENTOSA;

ANIMALS; BINDING SITES; COS CELLS; DITERPENES; GENES, DOMINANT; HUMANS; PHOSPHORYLATION; POINT MUTATION; RECOMBINANT PROTEINS; RETINALDEHYDE; RETINITIS PIGMENTOSA; RHODOPSIN;

ANIMALIA;

EID: 0031471940     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.25.13559     Document Type: Article

References (35)

1. Humphries, P., Kenna, P. & Farrar, J. G. (1992) Science 256, 804-808.
2. Berson, E. L. (1996) Proc. Natl. Acad. Sci. USA 93, 4526-4528.
3. Nathans, J. (1992) Biochemistry 31, 4923-4931.
4. Sung, C.-H., Makino, C., Baylor, D. & Nathans, J. (1994) J. Neurosci. 14, 5818-5833.
5. Min, K. C., Zvyaga, T. A., Cypess, A. M. & Sakmar, T. P. (1993) J. Biol. Chem. 268, 9400-9404.
6. Keen, T. J., Inglehearn, C. F., Lester, D. H., Bashir, R., Jay, M., Bird, A. C., Jay, B. & Bhattacharya, S. S. (1991) Genomics 11, 199-205.
7. Sullivan, J. M., Scott, K. M., Falls, H. F., Richards, J. H. E. & Sieving, P. A. (1993) Invest. Opthalmol. Visual Sci. 34, 1149 (abstr.).
8. Robinson, P. R., Cohen, G. B., Zhukovsky, E. A. & Oprian, D. D. (1992) Neuron 9, 719-725.
9. Cohen, G. B., Oprian, D. D. & Robinson, P. R. (1992) Biochemistry 31, 12592-12601.
10. Cohen, G. B., Yang, T., Robinson, P. R. & Oprian, D. D. (1993) Biochemistry 32, 6111-6115.
11. Rim, J. & Oprian, D. D. (1995) Biochemistry 34, 11938-11945.
12. Govardhan, C. P. & Oprian, D. D. (1994) J. Biol. Chem. 269, 6524-6527.
13. Zhukovsky, E. A., Robinson, P. R. & Oprian, D. D. (1991) Science 251, 558-560.
14. Tietze, L. F. & Eicher, T. (1989) Reactions and Syntheses In the Organic Chemistry Laboratory (Univ. Sci. Books, Mill Valley, CA), pp. 464-468.
15. Ishikawa, Y. (1964) Bull. Soc. Chem. Jpn. 37, 207-209.
16. Seyferth, D., Grim, S. O. & Read, T. O. (1961) J. Am. Chem. Soc. 83, 1617-1620.
17. Pfander, H., Lachenmeier, A. & Hadorn, M. (1980) Helv. Chim. Acta 63, 1377-1382.
18. Bergmann, E. D. & Migron, Y. (1976) Org. Prep. Proc. Int. 8, 75-80.
19. Buddrus, J. (1974) Chem. Ber. 107, 2050-2061.
20. Yamauchi, R., Miyake, N., Kato, K. & Ueno, Y. (1992) Biosci. Biotech. Biochem. 56, 1529-1532.
21. Ferretti, L., Karnik, S. S., Khorana, H. G., Nassal, M. & Oprian, D. D. (1986) Proc. Natl. Acad. Sci. USA 83, 599-603.
22. Oprian, D. D., Molday, R. S., Kaufman, R. J. & Khorana, H. G. (1987) Proc. Natl. Acad. Sci. USA 84, 8874-8878.
23. Zhukovsky, E. A. & Oprian, D. D. (1989) Science 246, 928-930.
24. Oprian, D. D. (1993) in Methods in Neurosciences, ed. Hargrave, P. A. (Academic, New York), Vol. 15, pp. 301-306.
25. Lorenz, W., Inglese, J., Palczewski, K., Onorato, J. J., Caron, M. G. & Lefkowitz, R. J. (1991) Proc. Natl. Acad. Sci. USA 88, 8715-8719.
26. Palczewski, K. (1993) in Methods in Neurosciences, ed. Hargrave, P. A. (Academic, New York), Vol. 15, pp. 217-225.
27. Lefkowitz, R. J. (1993) Nature (London) 365, 603-604.
28. Parma, J., Duprez, L., Van Sande, J., Cochaux, P., Gervy, C., Mockel, J., Dumont, J. & Vassart, G. (1993) Nature (London) 365, 649-651.
29. Shenker, A., Laue, L., Kosugi, S., Merendino, J. J., Jr., Minegishi, T. & Cutler, G. B., Jr. (1993) Nature (London) 365, 652-654.
30. Laue, L., Chan, W.-Y., Hsueh, A. J., Kudo, M., Hsu, S. Y., Wu, S.-M., Blomberg, L. & Cutler, G. B., Jr. ( 1995) Proc. Natl. Acad. Sci. USA 92, 1906-1910.
31. Schipani, E., Kruse, K. & Juppner, H. (1995) Science 268, 98-100.
32. Rao, V. R. & Oprian, D. D. (1996) Annu. Rev. Biophys. Biomol. Struct. 25, 287-314.
33. Li. T., Franson, W. K., Gordon, J. W., Berson, E. L. & Dryja, T. P. (1995) Proc. Natl. Acad. Sci. USA 92, 3551-3555.
34. Liri, T., Herzmark, P., Nakamoto, J. M., Van Dop, C. & Bourne, H. R. (1994) Nature (London) 371, 164-168.
35. Han, M. & Smith, S. O. (1995) Biochemistry 34, 1425-1432.