An European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: 2nd round

Toxicology

Volumn 212, Issue 1, 2005, Pages 69-79

  Ehling, G ^a   Hecht, M ^b   Heusener, A ^c   Huesler, J ^d   Gamer, A O ^e   Van Loveren, H ^f   Maurer, Th ^g   Riecke, K ^h   Ullmann, L ⁱ   Ulrich, P ^j   Vandebriel, R ^f   Vohr, H W ^k  

^a SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

^b FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^c MERCK KGAA   (Germany)

^d UNIVERSITY OF BERN   (Switzerland)

^e BASF SE   (Germany)

^f NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^g Swissmedic   (Switzerland)

^h BAYER PHARMA AG   (Germany)

ⁱ RCC Ltd   (Switzerland)

^j NOVARTIS PHARMA AG   (Switzerland)

^k BAYER AG   (Germany)

more..

Author keywords

Alternative models; Hypersensitivity; Immunotoxicity; Local lymph node assay (LLNA)

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; INFLAMMATION; LOCAL LYMPH NODE ASSAY; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; SKIN IRRITATION; STATISTICAL ANALYSIS; VALIDATION PROCESS;

ANIMALS; DERMATITIS, ALLERGIC CONTACT; ENDPOINT DETERMINATION; EUROPE; IRRITANTS; LABORATORIES; LOCAL LYMPH NODE ASSAY; MICE; MICE, INBRED BALB C; SKIN TESTS;

ANIMALIA; MURINAE;

EID: 20444399137     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2004.12.038     Document Type: Article

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