Nicergoline, a drug used for age-dependent cognitive impairment, protects cultured neurons against β-amyloid toxicity

Brain Research

Volumn 1047, Issue 1, 2005, Pages 30-37

  Caraci, Filippo ^a   Chisari, Mariangela ^a   Frasca, Giuseppina ^a   Canonico, Pier Luigi ^b   Battaglia, Angelo ^c   Calafiore, Marco ^a   Battaglia, Giuseppe ^d   Bosco, Paolo ^e   Nicoletti, Ferdinando ^d,f   Copani, Agata ^a,g   Sortino, Maria Angela ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^c PFIZER INC   (United States)

^d IRCCS NEUROMED   (Italy)

^e OASI RESEARCH INSTITUTE IRCCS   (Italy)

^f SAPIENZA UNIVERSITY OF ROME   (Italy)

^g CNR   (Italy)

Author keywords

Amyloid toxicity; Cortical neurons; Glial neuronal interaction; Nicergoline

Indexed keywords

ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; AMYLOID BETA PROTEIN[25-35]; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; METHYSERGIDE; NEUROTROPHIC FACTOR; NICERGOLINE; PRAZOSIN; PROTEIN BAX; PROTEIN BCL 2; SEROTONIN ANTAGONIST; TRANSFORMING GROWTH FACTOR BETA;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN CORTEX; BRAIN SLICE; CELL CULTURE; COGNITIVE DEFECT; CONTROLLED STUDY; CULTURE MEDIUM; DRUG WITHDRAWAL; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; APOPTOSIS; ASTROCYTES; BCL-2-ASSOCIATED X PROTEIN; CELL COMMUNICATION; CELLS, CULTURED; CEREBRAL CORTEX; COCULTURE TECHNIQUES; COGNITION DISORDERS; MEMORY DISORDERS; NERVE GROWTH FACTORS; NEURONS; NEUROPROTECTIVE AGENTS; NICERGOLINE; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY;

EID: 20444391320     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2005.04.004     Document Type: Article

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