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Volumn , Issue , 1999, Pages 495-540

Synthetic peptides as Malaria vaccines

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EID: 2042539038     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (1)

References (244)
  • 1
    • 0025044271 scopus 로고
    • Oral salmonella: Malaria circumsporozoite recombinants induce specific CD8+ cytotoxic T cells
    • Aggarwal, A., Kumar, S., Jaffe, R., Hone, D., Gross, M. and Sadoff, J. (1990). Oral Salmonella: malaria circumsporozoite recombinants induce specific CD8+ cytotoxic T cells. J. Exp. Med., 172, 1083–1090.
    • (1990) J. Exp. Med. , vol.172 , pp. 1083-1090
    • Aggarwal, A.1    Kumar, S.2    Jaffe, R.3    Hone, D.4    Gross, M.5    Sadoff, J.6
  • 2
    • 0029117046 scopus 로고
    • Immunogens containing sequences from antigen Pf332 induce plasmodium falciparum reactive antibodies which inhibit parasite growth but not cytoadherence
    • Ahlborg, N., Iqbal, J., Hansson, M., Uhlen, M., Mattei, D., Perlmann, P. et al. (1995). Immunogens containing sequences from antigen Pf332 induce Plasmodium falciparum reactive antibodies which inhibit parasite growth but not cytoadherence. Parasite Immunol., 17, 341–352.
    • (1995) Parasite Immunol. , vol.17 , pp. 341-352
    • Ahlborg, N.1    Iqbal, J.2    Hansson, M.3    Uhlen, M.4    Mattei, D.5    Perlmann, P.6
  • 3
    • 0028928920 scopus 로고
    • Synthesis of a diepitope multiple antigen peptide containing sequences from two malaria antigens using fmoc chemistry
    • Ahlborg, N. (1995). Synthesis of a diepitope multiple antigen peptide containing sequences from two malaria antigens using Fmoc chemistry. J. Immunol. Meth. 179, 269–275.
    • (1995) J. Immunol. Meth. , vol.179 , pp. 269-275
    • Ahlborg, N.1
  • 4
    • 0030964618 scopus 로고    scopus 로고
    • Enhanced immunogenicity of HIV-1 vaccine construct by modification of the native peptide sequence
    • Ahlers, J.D., Takeshita, T., Pendleton, CD. and Berzofsky, J.A. (1997). Enhanced immunogenicity of HIV-1 vaccine construct by modification of the native peptide sequence. PNAS, 94, 10856–10861.
    • (1997) PNAS , vol.94 , pp. 10856-10861
    • Ahlers, J.D.1    Takeshita, T.2    Pendleton, C.D.3    Berzofsky, J.A.4
  • 5
    • 0025287307 scopus 로고
    • Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide
    • Aichele, P. Hengartne H., Zinkernagel, R.M. and Schulz, M. (1990). Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide. J. Exp. Med., 171, 1815–1820
    • (1990) J. Exp. Med. , vol.171 , pp. 1815-1820
    • Aichele, P.1    Hengartne, H.2    Zinkernagel, R.M.3    Schulz, M.4
  • 7
    • 0029650205 scopus 로고
    • Identification of conserved antigenic components for a cytotoxic T lymphocyte-inducing vaccine against malaria
    • Aidoo, M., Lalvani, A Allsopp, C, Plebanski, M., Meisner, S., Krausa, P. et al. (1995). Identification of conserved antigenic components for a cytotoxic T lymphocyte-inducing vaccine against malaria. Lancet, 345, 1003–1007.
    • (1995) Lancet , vol.345 , pp. 1003-1007
    • Aidoo, M.1    Lalvani, A.2    Allsopp, C.3    Plebanski, M.4    Meisner, S.5    Krausa, P.6
  • 8
    • 0027318306 scopus 로고
    • Monoclonal antibodies of three different immunoglobulin g isotypes produced by immunization with a synthetic peptide or native protein protect mice against challenge with plasmodium yoelii sporozoites
    • Ak, M., Bower, J.H., Hoffman, S.L., Sedegah, M., Lees, A., Carter, M. et al. (1993). Monoclonal antibodies of three different immunoglobulin G isotypes produced by immunization with a synthetic peptide or native protein protect mice against challenge with Plasmodium yoelii sporozoites. Infect. Immun., 61, 2493–2497.
    • (1993) Infect. Immun. , vol.61 , pp. 2493-2497
    • Ak, M.1    Bower, J.H.2    Hoffman, S.L.3    Sedegah, M.4    Lees, A.5    Carter, M.6
  • 9
    • 0028675323 scopus 로고
    • Development of high potency universal dr-restricted helper epitopes by modification ofhigh affinity dr-blocking peptides
    • Alexander, J., Sidney, J., Southwood, S., Ruppert, J., Oseroff, C, Maewal, A. et al. (1994) Development of high potency universal DR-restricted helper epitopes by modification ofhigh affinity DR-blocking peptides. Immunity, 1, 751–761.
    • (1994) Immunity , vol.1 , pp. 751-761
    • Alexander, J.1    Sidney, J.2    Southwood, S.3    Ruppert, J.4    Oseroff, C.5    Maewal, A.6
  • 10
    • 9444289849 scopus 로고    scopus 로고
    • Comparison of numerous delivery systems for the induction of cytotoxic T lymphocytes by immunization
    • Allsopp, C.E., Plebanski, M., Gilbert, S., Sinden, R.E., Haris, S., Frankel, G. et al. (1997). Comparison of numerous delivery systems for the induction of cytotoxic T lymphocytes by immunization. Eur. J. Immunol, 26, 1951–1959
    • (1997) Eur. J. Immunol. , vol.26 , pp. 1951-1959
    • Allsopp, C.E.1    Plebanski, M.2    Gilbert, S.3    Sinden, R.E.4    Haris, S.5    Frankel, G.6
  • 11
    • 0022374357 scopus 로고
    • Circumsporozoite protein of plasmodium vivax: Gene cloning and characterization of the immunodominant epitope
    • Arnot, D.E., Barnwell, J.W., Tam, J.P., Nussenzweig, V., Nussenzweig, R.S. et al. (1985). Circumsporozoite protein of Plasmodium vivax: Gene cloning and characterization of the immunodominant epitope. Science, 230, 815–816.
    • (1985) Science , vol.230 , pp. 815-816
    • Arnot, D.E.1    Barnwell, J.W.2    Tam, J.P.3    Nussenzweig, V.4    Nussenzweig, R.S.5
  • 12
    • 0025905198 scopus 로고
    • Immunofluorescent microscopical visualization of trails left by gliding crypptosporodium parvum sporozoites
    • Arrowood, M.J., Sterling, CR. and Healey, M.C (1991). Immunofluorescent microscopical visualization of trails left by gliding Crypptosporodium parvum sporozoites.J. Parasitol., 77, 315–317.
    • (1991) J. Parasitol. , vol.77 , pp. 315-317
    • Arrowood, M.J.1    Sterling, C.R.2    Healey, M.C.3
  • 13
    • 37049101880 scopus 로고
    • Solid-phase peptide synthesis using noc-fluorenylmethoxycarbonyl amino acid pentafluorophenyl esters
    • Atherton, E. and Sheppard, R.C (1985). Solid-phase peptide synthesis using Noc-fluorenylmethoxycarbonyl amino acid pentafluorophenyl esters. J. Chem. Soc. Chem. Commun., 3, 165–166.
    • (1985) J. Chem. Soc. Chem. Commun. , vol.3 , pp. 165-166
    • Atherton, E.1    Sheppard, R.C.2
  • 14
    • 0025458610 scopus 로고
    • Characterization of malaria transmission by anopheles (Diptera:Culeidae) in western kenya in preparation for malaria vaccine trials
    • Beier, J. Perkins, P.V., Onyango, F.K., Gargan, T.P., Oster, CN., Whitmire, R.E. et al. (1990). Characterization of malaria transmission by Anopheles (Diptera:Culeidae) in western Kenya in preparation for malaria vaccine trials. J. Med. Entomol., 27, 570–577.
    • (1990) J. Med. Entomol , vol.27 , pp. 570-577
    • Beier, J.1    Perkins, P.V.2    Onyango, F.K.3    Gargan, T.P.4    Oster, C.N.5    Whitmire, R.E.6
  • 15
    • 0030959609 scopus 로고    scopus 로고
    • Lipopeptide immunization without adjuvant induces potent and long-1 as ting, B, T helper, and cytotoxic T lymphocyte responses against a malaria liver stage antigen in mice and chimpanzees
    • BenMohamed, L., Gras-Masse, H., Tartar, A., Daubersies, P., Brahimi, K., Bossus, M. et al. (1997). Lipopeptide immunization without adjuvant induces potent and long-1 as ting, B, T helper, and cytotoxic T lymphocyte responses against a malaria liver stage antigen in mice and chimpanzees. Eur. J. Immunol., 27, 1242–1253.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 1242-1253
    • BenMohamed, L.1    Gras-Masse, H.2    Tartar, A.3    Daubersies, P.4    Brahimi, K.5    Bossus, M.6
  • 16
    • 0019959784 scopus 로고
    • Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence
    • Bittle, J.L., Houghten, R.A., Alexander, H., Shinnick, T.M., Sutcliff, J.G., Lemer R.A et al. (1982). Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence. Nature, 298, 30–33.
    • (1982) Nature , vol.298 , pp. 30-33
    • Bittle, J.L.1    Houghten, R.A.2    Alexander, H.3    Shinnick, T.M.4    Sutcliff, J.G.5    Lemer, R.A.6
  • 17
    • 85057687969 scopus 로고
    • Elicitation of specific cytotoxic T cells by immunization with malaria soluble synthetic polypeptides
    • Blum-Tirouvanziam, U., Beghdadi-Rais, C, Roggero, M.A., Valmori, D., Bertholet, S., Bron, C et al. (1994). Elicitation of specific cytotoxic T cells by immunization with malaria soluble synthetic polypeptides, J. Immunol., 154, 3922–3931.
    • (1994) J. Immunol. , vol.154 , pp. 3922-3931
    • Blum-Tirouvanziam, U.1    Beghdadi-Rais, C.2    Roggero, M.A.3    Valmori, D.4    Bertholet, S.5    Bron, C.6
  • 18
    • 14844345985 scopus 로고
    • Localization of HLA-DQ restricted T cell epitopes in the circumsporozoite protein of plasmodium falciparum
    • Blum-Tirouvanziam, U., Servis, C, Habluetzel, A., Valmori, D., Men, Y., Esposito, F et al. (1995). Localization of HLA-DQ restricted T cell epitopes in the circumsporozoite protein of Plasmodium falciparum. J. Immunol., 154, 3922–3931.
    • (1995) J. Immunol. , vol.154 , pp. 3922-3931
    • Blum-Tirouvanziam, U.1    Servis, C.2    Habluetzel, A.3    Valmori, D.4    Men, Y.5    Esposito, F.6
  • 19
    • 0028131274 scopus 로고
    • Efficacy of synthetic vaccines in the induction of cytotoxic T lymphocytes. Comparison of the costimulating support provided by helper T cells and lipoamino acid
    • Borges, E., Wiesmuller, K.H., Jung, G. and Walden, P. (1994). Efficacy of synthetic vaccines in the induction of cytotoxic T lymphocytes. Comparison of the costimulating support provided by helper T cells and lipoamino acid. J. Immunol. Meth., 173, 253–263.
    • (1994) J. Immunol. Meth. , vol.173 , pp. 253-263
    • Borges, E.1    Wiesmuller, K.H.2    Jung, G.3    Walden, P.4
  • 20
    • 0028316559 scopus 로고
    • Simian immunodeficiency virus as a model for vaccination against HIV. Induction in rhesus macaques of gag- or nef-specific cytotoxic T lymphocytes by lipopeptides
    • Bourgault, I, Chirat, F, Tartar, A., Leby, J.P, Guillet, J.G. and Venet, A. (1994). Simian immunodeficiency virus as a model for vaccination against HIV. Induction in rhesus macaques of GAG- or NEF-specific cytotoxic T lymphocytes by lipopeptides. J. Immunol., 152, 2530–2537.
    • (1994) J. Immunol. , vol.152 , pp. 2530-2537
    • Bourgault, I.1    Chirat, F.2    Tartar, A.3    Leby, J.P.4    Guillet, J.G.5    Venet, A.6
  • 21
    • 0347585059 scopus 로고
    • Is the acquired heterologous immunity to plasmodium vivax equally effective against sporozoites and trophozoites
    • Boyd, M.F. and Kitchen, S.F. (1936). Is the acquired heterologous immunity to Plasmodium vivax equally effective against sporozoites and trophozoites? Am. J. Trop. Med., 16, 317–322.
    • (1936) Am. J. Trop. Med. , vol.16 , pp. 317-322
    • Boyd, M.F.1    Kitchen, S.F.2
  • 22
    • 0017199063 scopus 로고
    • Vaccination against plasmodium falciparum: A negative result
    • Bray, R.S. (1976). Vaccination against Plasmodium falciparum: A negative result. Trans. Roy. Soc. of Trop. Med. Hyg., 70, 258.
    • (1976) Trans. Roy. Soc. of Trop. Med. Hyg. , vol.70 , pp. 258
    • Bray, R.S.1
  • 23
    • 0026756205 scopus 로고
    • Recognition of different domains of the plasmodium falciparum CS protein by the sera of naturally-infected individuals compared with those of sporozoite-immunized volunteers
    • Calvo-Calle, J.M., Nardin, E.H., Clavijo, P., Boudin, C., Stuber, D., Takacs, B. et al. (1992). Recognition of different domains of the Plasmodium falciparum CS protein by the sera of naturally-infected individuals compared with those of sporozoite-immunized volunteers. J. Immunol., 149, 2695–2701.
    • (1992) J. Immunol. , vol.149 , pp. 2695-2701
    • Calvo-Calle, J.M.1    Nardin, E.H.2    Clavijo, P.3    Boudin, C.4    Stuber, D.5    Takacs, B.6
  • 24
    • 0027155469 scopus 로고
    • Immunogenicity of multiple antigen peptides containing b and non-repeat T cell epitopes of the circumsporozoite protein of plasm odium falciparum
    • Calvo-Calle, J. M., de Oliveira, G.A., Clavijo, P., Maracic, M., Tam, J. P., Lu, Y. A. et al. (1993). Immunogenicity of multiple antigen peptides containing B and non-repeat T cell epitopes of the circumsporozoite protein of Plasm odium falciparum. J. Immunol., 150, 1403–1412.
    • (1993) J. Immunol. , vol.150 , pp. 1403-1412
    • Calvo-Calle, J.M.1    De Oliveira, G.A.2    Clavijo, P.3    Maracic, M.4    Tam, J.P.5    Lu, Y.A.6
  • 25
    • 0031202831 scopus 로고    scopus 로고
    • Binding of malaria T cell epitopes to dr and dq molecules in vitro correlates with immunogenicity in vivo. Identification of a universal T cell epitope in the plasmodium falciparum circumsporozoite protein
    • Calvo-Calle, J.M., Hammer, J., Sinigaglia, F, Clavijo, P., Moya-Castro, Z.R. and Nardin, E.H. (1997). Binding of malaria T cell epitopes to DR and DQ molecules in vitro correlates with immunogenicity in vivo. Identification of a universal T cell epitope in the Plasmodium falciparum circumsporozoite protein. J. Immunol., 159, 1362–1373.
    • (1997) J. Immunol. , vol.159 , pp. 1362-1373
    • Calvo-Calle, J.M.1    Hammer, J.2    Sinigaglia, F.3    Clavijo, P.4    Moya-Castro, Z.R.5    Nardin, E.H.6
  • 26
    • 0026795458 scopus 로고
    • The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of plasmodium falciparum sporozoites
    • Cerami, C., Frevert, U., Sinnis, P., Takacs, B., Clavijo, P., Santos, M.J. etal. (1992). The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of Plasmodium falciparum sporozoites. Cell, 70, 1021–1033.
    • (1992) Cell , vol.70 , pp. 1021-1033
    • Cerami, C.1    Frevert, U.2    Sinnis, P.3    Takacs, B.4    Clavijo, P.5    Santos, M.J.6
  • 27
    • 0023130512 scopus 로고
    • Characterization of plasmodium yoelii monoclonal antibodies directed against stage specific sporozoite antigens
    • Charoenvit, Y, Leef, M., Yuan, L., Sedegan, M. and Beaudoin, R. (1987). Characterization of Plasmodium yoelii monoclonal antibodies directed against stage specific sporozoite antigens. Infect. Immun., 55, 604608.
    • (1987) Infect. Immun. , vol.55 , pp. 604-608
    • Charoenvit, Y.1    Leef, M.2    Yuan, L.3    Sedegan, M.4    Beaudoin, R.5
  • 28
    • 0025974754 scopus 로고
    • Monoclonal, but not polyclonal, antibodies protect against plasmodium yoelii sporozoites
    • Charoenvit, Y., Mellouk, S., Cole, C, Bechara, R., Leef, M.F, Sedegah, M. et al. (1991a). Monoclonal, but not polyclonal, antibodies protect against Plasmodium yoelii sporozoites. J. Immunol., 146, 1020–1025.
    • (1991) J. Immunol. , vol.146 , pp. 1020-1025
    • Charoenvit, Y.1    Mellouk, S.2    Cole, C.3    Bechara, R.4    Leef, M.F.5    Sedegah, M.6
  • 29
    • 0025777484 scopus 로고
    • Inability of malaria vaccine to induce antibodies to a protective epitope within its sequence
    • Charoenvit, Y., Collins, W.E., Jones, T.R., Millet, P., Yuan, L., Campbell, G.H. et al. (1991b). Inability of malaria vaccine to induce antibodies to a protective epitope within its sequence. Science, 251, 668–671.
    • (1991) Science , vol.251 , pp. 668-671
    • Charoenvit, Y.1    Collins, W.E.2    Jones, T.R.3    Millet, P.4    Yuan, L.5    Campbell, G.H.6
  • 30
    • 0030760780 scopus 로고    scopus 로고
    • Development of two monoclonal antibodies against plasmodium falciparum sporozoite surface protein 2 and mapping of b cell epitopes
    • Charoenvit, Y., Fallarme, V, Roger, W.O., Sacci, J.B., Kaur, M., Aguiar, J.C. et al. (1997). Development of two monoclonal antibodies against Plasmodium falciparum sporozoite surface protein 2 and mapping of B cell epitopes. Infect. Immun., 65, 3430–3437.
    • (1997) Infect. Immun. , vol.65 , pp. 3430-3437
    • Charoenvit, Y.1    Fallarme, V.2    Roger, W.O.3    Sacci, J.B.4    Kaur, M.5    Aguiar, J.C.6
  • 31
    • 0028783523 scopus 로고
    • Fine specificity of immune responses to epitopic sequence in synthetic peptides containing b and T epitopes from the conserved plasmodium falciparum blood stage antigens
    • Chattergee, S., Sharma, P., Kumar, S. and Chauhan, VS. (1995). Fine specificity of immune responses to epitopic sequence in synthetic peptides containing B and T epitopes from the conserved Plasmodium falciparum blood stage antigens. Vaccine, 13, 1474–1481.
    • (1995) Vaccine , vol.13 , pp. 1474-1481
    • Chattergee, S.1    Sharma, P.2    Kumar, S.3    Chauhan, V.S.4
  • 32
    • 0017615342 scopus 로고
    • Immunity to sporozoite-induced malaria infection in mice. I the effect of immunization of T and b cell-deficient mice
    • Chen, D.H., Tigelaar, R.E. and Weinbaum, F (1977). Immunity to sporozoite-induced malaria infection in mice. I The effect of immunization of T and B cell-deficient mice. J. Imm unol., 118, 1322–1327.
    • (1977) J. Imm Unol. , vol.118 , pp. 1322-1327
    • Chen, D.H.1    Tigelaar, R.E.2    Weinbaum, F.3
  • 33
    • 0015699215 scopus 로고
    • Immunization of man against sporozoite induced falciparum malaria
    • Clyde, D.F., Most, H., McCarthy, V and Vanderberg, J.P. (1973a). Immunization of man against sporozoite induced falciparum malaria. Am. J. Med. Sci., 266, 169–177.
    • (1973) Am. J. Med. Sci. , vol.266 , pp. 169-177
    • Clyde, D.F.1    Most, H.2    McCarthy, V.3    Vanderberg, J.P.4
  • 34
    • 0015736375 scopus 로고
    • Specificity of protection of man immunized against sporozoite induced falciparum malaria
    • Clyde, D.E, McCarthy, V.C., Miller, R.M., and Hornick, R.B. (1973b). Specificity of protection of man immunized against sporozoite induced falciparum malaria. Am. J. Med. Sci., 266, 398–403.
    • (1973) Am. J. Med. Sci. , vol.266 , pp. 398-403
    • Clyde, D.E.1    McCarthy, V.C.2    Miller, R.M.3    Hornick, R.B.4
  • 35
    • 0016740645 scopus 로고
    • Immunization of man against falciparum and vivax malaria by use of attenuated sporozoites
    • Clyde, D.E, McCarthy, V., Miller, R.M and Woodward, W.E. (1975). Immunization of man against falciparum and vivax malaria by use of attenuated sporozoites. Am. J. Trop. Med. Hyg., 24, 397–401.
    • (1975) Am. J. Trop. Med. Hyg. , vol.24 , pp. 397-401
    • Clyde, D.E.1    McCarthy, V.2    Miller, R.M.3    Woodward, W.E.4
  • 36
    • 0017256436 scopus 로고
    • Antibody-induced ultrastructural changes of malarial sporozoites
    • Cochrane, A.H., Aikawa, M., Jeng, M. and Nussenzweig, R.S. (1976). Antibody-induced ultrastructural changes of malarial sporozoites. J. Immunol., 116, 859–867.
    • (1976) J. Immunol. , vol.116 , pp. 859-867
    • Cochrane, A.H.1    Aikawa, M.2    Jeng, M.3    Nussenzweig, R.S.4
  • 37
    • 0020421811 scopus 로고
    • Monoclonal antibodies identify the protective antigens of sporozoites of plasmodium knowlesi
    • Cochrane, A.H., Santoro, F., Nussenzweig, Y, Gwadz, R.W. and Nussenzweig R.S. (1982). Monoclonal antibodies identify the protective antigens of sporozoites of Plasmodium knowlesi. PNAS, 79, 5651–5655.
    • (1982) PNAS , vol.79 , pp. 5651-5655
    • Cochrane, A.H.1    Santoro, F.2    Nussenzweig, Y.3    Gwadz, R.W.4    Nussenzweig, R.S.5
  • 38
    • 0030893431 scopus 로고    scopus 로고
    • Protective immunity induced in squirrel monkeys with a multiple anitgen construct against the circumsporozoite protein of plasmodium vivax
    • Collins, WE., Sullivan, J.S., Morris, C.L., Galland, G.G., Jue, D.L., Fang, S. et al. (1997). Protective immunity induced in squirrel monkeys with a multiple anitgen construct against the circumsporozoite protein of Plasmodium vivax. Am. J. Trop. Med. Hyg., 56, 200–210.
    • (1997) Am. J. Trop. Med. Hyg. , vol.56 , pp. 200-210
    • Collins, W.E.1    Sullivan, J.S.2    Morris, C.L.3    Galland, G.G.4    Jue, D.L.5    Fang, S.6
  • 39
    • 0026680347 scopus 로고
    • Expression of thrombospondin-related anonymous protein in plasmodium falciparum sporozoites
    • Cowan, G., Krishna, S., Crisanti, A. and Robson, K. (1992). Expression of thrombospondin-related anonymous protein in Plasmodium falciparum sporozoites. Lancet, 339, 1412–1413.
    • (1992) Lancet , vol.339 , pp. 1412-1413
    • Cowan, G.1    Krishna, S.2    Crisanti, A.3    Robson, K.4
  • 41
    • 37049184983 scopus 로고
    • Structure of the gene encoding the immunodominant surface antigen on the sporozoite of the human malaria parasite plasmodium falciparum
    • Dame, J.B., Williams, J.L., McCutchan, T.E, Weber, J.L., Wirtz, R.A., Hockmeyer, WT et al. (1984). Structure of the gene encoding the immunodominant surface antigen on the sporozoite of the human malaria parasite Plasmodium falciparum. Science, 225, 593–99.
    • (1984) Science , vol.225 , pp. 593-599
    • Dame, J.B.1    Williams, J.L.2    McCutchan, T.E.3    Weber, J.L.4    Wirtz, R.A.5    Hockmeyer, W.T.6
  • 42
    • 0019308191 scopus 로고
    • Sporozoites of mammalian malaria: Attachment to and interiorization and fate within macrophages
    • Danforth, H.D., Aikawa, M., Cochrane, A. and Nussenzweig, R.S. (1980). Sporozoites of mammalian malaria: attachment to and interiorization and fate within macrophages. J. Protozool., 27, 193–202.
    • (1980) J. Protozool. , vol.27 , pp. 193-202
    • Danforth, H.D.1    Aikawa, M.2    Cochrane, A.3    Nussenzweig, R.S.4
  • 43
    • 0026460195 scopus 로고
    • Protection of mice and nude rats against toxoplasmosis by a multiple antigenic peptide construction derived from toxoplasma gondii p30 anti gen
    • Darcy, F., Maes, P., Gras-Masse, H., Auriault, C., Bossus, M., Deslee, D. et al. (1992). Protection of mice and nude rats against toxoplasmosis by a multiple antigenic peptide construction derived from Toxoplasma gondii p30 anti gen. J. Imm unol., 149, 3636–3641.
    • (1992) J. Imm Unol. , vol.149 , pp. 3636-3641
    • Darcy, F.1    Maes, P.2    Gras-Masse, H.3    Auriault, C.4    Bossus, M.5    Deslee, D.6
  • 44
    • 0026582230 scopus 로고
    • Macromoleeular assemblage in the design of a synthetic aids vaccine
    • Defoort, J.P., Nardelli, B., Huang, W., Ho, D.D. and Tam, J.P. (1992). Macromoleeular assemblage in the design of a synthetic AIDS vaccine. PNAS, 89, 3879–3883.
    • (1992) PNAS , vol.89 , pp. 3879-3883
    • Defoort, J.P.1    Nardelli, B.2    Huang, W.3    Ho, D.D.4    Tam, J.P.5
  • 45
    • 0024398814 scopus 로고
    • Human T cell recognition of polymorphic epitopes from malaria circumsporozoite protein
    • De Groot, A., Johnson, A, Maloy, W., Quakyi, I., Riley, E., Menon, A. et al. (1989). Human T cell recognition of polymorphic epitopes from malaria circumsporozoite protein. J. Immunol., 142, 4000–4005.
    • (1989) J. Immunol. , vol.142 , pp. 4000-4005
    • De Groot, A.1    Johnson, A.2    Maloy, W.3    Quakyi, I.4    Riley, E.5    Menon, A.6
  • 46
    • 0028146438 scopus 로고
    • Immunogenicity of an alum-adsorbed synthetic multiple antigen peptide based on B- and T-cell epitopes of the plasmodium falciparum CS protein: Possible vaccine application
    • de Oliveira, G.A, Clavijo, P., Nussenzweig, RS. and Nardin, E.H. (1994). Immunogenicity of an alum-adsorbed synthetic multiple antigen peptide based on B- and T-cell epitopes of the Plasmodium falciparum CS protein: Possible vaccine application. Vaccine, 12, 1012–1017.
    • (1994) Vaccine , vol.12 , pp. 1012-1017
    • De Oliveira, G.A.1    Clavijo, P.2    Nussenzweig, R.S.3    Nardin, E.H.4
  • 47
    • 0023026360 scopus 로고
    • The antibody response in mice to carrier-free synthetic polymers of plasmodium falciparum circumsporozotie repetitive epitope is I-Ab restricted: Possible implications for malaria vaccine
    • Del Giudice, G., Cooper, J.A, Merino, J., Verdini, AS., Pessi, A, Togna, R. et al. (1986). The antibody response in mice to carrier-free synthetic polymers of Plasmodium falciparum circumsporozotie repetitive epitope is I-Ab restricted: possible implications for malaria vaccine. Immunol., 137, 2952–2955.
    • (1986) Immunol , vol.137 , pp. 2952-2955
    • Del Giudice, G.1    Cooper, J.A.2    Merino, J.3    Verdini, A.S.4    Pessi, A.5    Togna, R.6
  • 48
    • 0025298242 scopus 로고
    • A multiple antigen peptide from the repetitive sequence of the plasmodiummalariae circumsporozoite protein induces a specific antibody response in mice of various H-2 haplotypes
    • Del Giudice, G., Tougne, C., Louis, J.A, Lambert, P-H., Bianchi, E., Bonelli, F et al. (1990). A multiple antigen peptide from the repetitive sequence of the Plasmodiummalariae circumsporozoite protein induces a specific antibody response in mice of various H-2 haplotypes. Eur. Immunol., 20, 1619–1622.
    • (1990) Eur. Immunol. , vol.20 , pp. 1619-1622
    • Del Giudice, G.1    Tougne, C.2    Louis, J.A.3    Lambert, P.-H.4    Bianchi, E.5    Bonelli, F.6
  • 49
    • 0030955428 scopus 로고    scopus 로고
    • Potent immunogenic short linear peptide constructs composed of b cell epitopes and pan dr T helper epitopes (Padre), for antibody responses in vivo
    • del Guercio, M.F., Alexander, J., Kubo, R.T., Arrhenius, T., Maewal, A., Appella, E. et al. (1997). Potent immunogenic short linear peptide constructs composed of B cell epitopes and Pan DR T helper epitopes (PADRE), for antibody responses in vivo. Vaccine, 15, 441–448.
    • (1997) Vaccine , vol.15 , pp. 441-448
    • Del Guercio, M.F.1    Alexander, J.2    Kubo, R.T.3    Arrhenius, T.4    Maewal, A.5    Appella, E.6
  • 50
    • 0024389666 scopus 로고
    • In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine
    • Deres, K., Schild, H., Wiesmuller, K.-H., Jung, G. and Rarnmensee, H.-G. (1989). In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine. Nature, 342, 561–564.
    • (1989) Nature , vol.342 , pp. 561-564
    • Deres, K.1    Schild, H.2    Wiesmuller, K.-H.3    Jung, G.4    Rarnmensee, H.-G.5
  • 52
    • 0026333316 scopus 로고
    • Geographically restricted heterogeneity of the plasmodium falciparum circumsporozoite protein: Relevance for vaccine development
    • Doolan, D.L., Saul, AJ. and Good, M.F. (1992). Geographically restricted heterogeneity of the Plasmodium falciparum circumsporozoite protein: Relevance for vaccine development. Infect. Immun., 60, 675–682.
    • (1992) Infect. Immun. , vol.60 , pp. 675-682
    • Doolan, D.L.1    Saul, A.J.2    Good, M.F.3
  • 53
    • 0022446646 scopus 로고
    • Levels of antibodies to plasmodium falciparum sporozoite surface antigens reflect malaria transmission rates and are persistent in the absence of reinfection
    • Druilhe, P., Pradier, O., Marc, J.P., Miltgen, E, Mazier, D. and Parent, G. (1986). Levels of antibodies to Plasmodium falciparum sporozoite surface antigens reflect malaria transmission rates and are persistent in the absence of reinfection. Infect. Immun., 53, 393–397.
    • (1986) Infect. Immun. , vol.53 , pp. 393-397
    • Druilhe, P.1    Pradier, O.2    Marc, J.P.3    Miltgen, E.4    Mazier, D.5    Parent, G.6
  • 54
    • 0027328971 scopus 로고
    • Long-term persistence of sterile immunity in a volunteer immunized with X-irradiated plasmodium falciparum sporozoites
    • Edelman, R., Hoffman, S.L., Davis, J.R., Beier, M., Sztein, M.B., Losonsky, G. et al. (1993). Long-term persistence of sterile immunity in a volunteer immunized with X-irradiated Plasmodium falciparum sporozoites. J. Infect. Dis., 168, 1066–1070.
    • (1993) J. Infect. Dis. , vol.168 , pp. 1066-1070
    • Edelman, R.1    Hoffman, S.L.2    Davis, J.R.3    Beier, M.4    Sztein, M.B.5    Losonsky, G.6
  • 55
    • 0022816109 scopus 로고
    • Circumsporozoite protein of plasmodium berghei: Gene cloning and identification of the immunodominant epitopes
    • Eichinger, D.J., Arnot, D.E., Tam, J.P., Nussenzweig, V. and Enea, V. (1986). Circumsporozoite protein of Plasmodium berghei: Gene cloning and identification of the immunodominant epitopes. Mol. Cell. Biol., 6, 3965–3972.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 3965-3972
    • Eichinger, D.J.1    Arnot, D.E.2    Tam, J.P.3    Nussenzweig, V.4    Enea, V.5
  • 56
    • 0023235563 scopus 로고
    • Efficacy of murine malaria sporozoite vaccine: Implications for human vaccine development
    • Egan, J.E., Weber, J.L., Ballou, W.R., Hollingdale, M.R., Majarian, W.R., Gordon, D.M. et al. (1987). Efficacy of murine malaria sporozoite vaccine: Implications for human vaccine development. Science, 236, 453456.
    • (1987) Science , vol.236 , pp. 453-456
    • Egan, J.E.1    Weber, J.L.2    Ballou, W.R.3    Hollingdale, M.R.4    Majarian, W.R.5    Gordon, D.M.6
  • 57
    • 0027292347 scopus 로고
    • Humoral immune responses in volunteers immunized with radiation attenuated p. Falciparum sporozoites
    • Egan, J.E., Hoffman, S.L., Haynes, J.D., Sadoff, J.C., Schneider, I., Grau, G.E. et al. (1993). Humoral immune responses in volunteers immunized with radiation attenuated P. falciparum sporozoites. Am. J. Trop. Med. Hyg., 49, 166–173.
    • (1993) Am. J. Trop. Med. Hyg. , vol.49 , pp. 166-173
    • Egan, J.E.1    Hoffman, S.L.2    Haynes, J.D.3    Sadoff, J.C.4    Schneider, I.5    Grau, G.E.6
  • 58
    • 0024854635 scopus 로고
    • Secretion of trails during gliding motility of eimf'ria nieshulzi (Apicomplexa, coccidia) sporozoites visualized by a monoclonal antibody and immuno gold-silver enhancement
    • Entzeroth, R., Zgrzebski, G. and Dubremetz, J.-F. (1989). Secretion of trails during gliding motility of Eimf'ria nieshulzi (Apicomplexa, Coccidia) sporozoites visualized by a monoclonal antibody and immuno gold-silver enhancement. Parasitol. Res., 76,174–175.
    • (1989) Parasitol. Res. , vol.76 , pp. 174-175
    • Entzeroth, R.1    Zgrzebski, G.2    Dubremetz, J.-F.3
  • 59
    • 0023858088 scopus 로고
    • Assessment in humans of a synthetic peptide-based vaccine against the sporozoite stage of the human malaria parasite plasmodium falciparum
    • Etlinger, H.M., Felix, A.M., Gillessen, D., Heimer, E.P., Just, M., Pink, J.R.L. et al. (1988). Assessment in humans of a synthetic peptide-based vaccine against the sporozoite stage of the human malaria parasite Plasmodium falciparum. J. Immunol., 140, 626–633.
    • (1988) J. Immunol. , vol.140 , pp. 626-633
    • Etlinger, H.M.1    Felix, A.M.2    Gillessen, D.3    Heimer, E.P.4    Just, M.5    Pink, J.R.L.6
  • 61
    • 0026327141 scopus 로고
    • In vivo induction of cytolytic T cell response by a free synthetic peptide requires CD4+ T cell help
    • Fayolle, C., Deriaud, E. and Leclerc, C. (1991). In vivo induction of cytolytic T cell response by a free synthetic peptide requires CD4+ T cell help. J. Immunol., 147, 4069–4073.
    • (1991) J. Immunol. , vol.147 , pp. 4069-4073
    • Fayolle, C.1    Deriaud, E.2    Leclerc, C.3
  • 62
    • 0027320440 scopus 로고
    • Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells
    • Feltkamp, M.C., Smits, H.L., Vierboom, M.P., Minnaar, R.E, de Jongh, B.M., Drijfhout, J.W. et al. (1993). Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells. Eur. J. Immunol., 23, 2242–2249.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2242-2249
    • Feltkamp, M.C.1    Smits, H.L.2    Vierboom, M.P.3    Minnaar, R.E.4    De Jongh, B.M.5    Drijfhout, J.W.6
  • 63
    • 37049185845 scopus 로고
    • Inhibition of development of exoerythrocytic forms of malaria parasites by gamma-interferon
    • Ferreira, A., Schofield, L., Enea, v., Schellekens, H., van der Meide, P, Collins, W.E. et al. (1986). Inhibition of development of exoerythrocytic forms of malaria parasites by gamma-interferon. Science, 232, 881884.
    • (1986) Science , vol.232 , pp. 881-884
    • Ferreira, A.1    Schofield, L.2    Enea, V.3    Schellekens, H.4    Van Der Meide, P.5    Collins, W.E.6
  • 64
    • 0031255317 scopus 로고    scopus 로고
    • Induction of protective CTL responses against tile plasmodium yo elii circumsporozoite protein by immunization with peptides
    • Franke, E.D., Corradin, G. and Hoffman, S.L. (1997). Induction of protective CTL responses against tile Plasmodium yo elii circumsporozoite protein by immunization with peptides. Imm unol., 159, 34243433.
    • (1997) Imm Unol. , vol.159 , pp. 3424-3433
    • Franke, E.D.1    Corradin, G.2    Hoffman, S.L.3
  • 65
    • 0027457377 scopus 로고
    • Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes
    • Frevert, U., Sinnis, P., Cerami, C., Shreffler, W., Takacs, B. and Nussenzweig, V. (1993). Malaria circumsporozoite protein binds to heparan sulfate proteoglycans associated with the surface membrane of hepatocytes. J. Exp. Med., 177, 1287–1298.
    • (1993) J. Exp. Med. , vol.177 , pp. 1287-1298
    • Frevert, U.1    Sinnis, P.2    Cerami, C.3    Shreffler, W.4    Takacs, B.5    Nussenzweig, V.6
  • 66
    • 0026571596 scopus 로고
    • Liposomal malaria vaccine in humans: A safe and potent adjuvant strategy
    • Fries, L.F., Gordon, D.M., Richards, R.L., Egan, J.E., Hollingdale, M.R., Gross, M. et al. (1992). Liposomal malaria vaccine in humans: a safe and potent adjuvant strategy. PNAS, 89, 358--362.
    • (1992) PNAS , vol.89 , pp. 358-362
    • Fries, L.F.1    Gordon, D.M.2    Richards, R.L.3    Egan, J.E.4    Hollingdale, M.R.5    Gross, M.6
  • 68
    • 0022513753 scopus 로고
    • Genetic control of the immune response in mice to plasmodium falciparum sporozoite vaccine
    • Widespread non-responsiveness to single malaria T epitope in highly repetitive vaccine
    • Good, M.F., Berzofsky, J.A., Maloy, W.L., Hayashi, Y, Fujii, N., Hockmeyer, W.T. et al. (1986). Genetic control of the immune response in mice to Plasmodium falciparum sporozoite vaccine. Widespread non-responsiveness to single malaria T epitope in highly repetitive vaccine. J. Exp. Med., 164, 655–660.
    • (1986) J. Exp. Med. , vol.164 , pp. 655-660
    • Good, M.F.1    Berzofsky, J.A.2    Maloy, W.L.3    Hayashi, Y.4    Fujii, N.5    Hockmeyer, W.T.6
  • 69
    • 0023146862 scopus 로고
    • Construction of synthetic immunogen: Use of new T-helper epitope on malaria circumsporozoite protein
    • Good, M.F., Maloy, W.L., Lunde, M.N., Margalit, H., Cornette, J.L., Smith, G.L. et al. (1987). Construction of synthetic immunogen: use of new T-helper epitope on malaria circumsporozoite protein. Science, 235, 1059–1062.
    • (1987) Science , vol.235 , pp. 1059-1062
    • Good, M.F.1    Maloy, W.L.2    Lunde, M.N.3    Margalit, H.4    Cornette, J.L.5    Smith, G.L.6
  • 70
    • 0023869487 scopus 로고
    • Human T-cell recognition of the circumsporozoite protein of plasmodium falciparum: Immuno dominant T-cell domains map to the polymorphic regions of the molecule
    • Good, M.F., Pombo, D., Quakyi, LA., Riley, E M., Houghten, R.A., Menon, A. et al. (1988). Human T-cell recognition of the circumsporozoite protein of Plasmodium falciparum: immuno dominant T-cell domains map to the polymorphic regions of the molecule. PNAS, 85, 1199–1203.
    • (1988) PNAS , vol.85 , pp. 1199-1203
    • Good, M.F.1    Pombo, D.2    Quakyi, L.A.3    Riley, E.M.4    Houghten, R.A.5    Menon, A.6
  • 72
    • 0025322801 scopus 로고
    • Immune responses to defined epitopes of the circumsporozoite protein of the murine malaria parasite, plasmodium yoelii
    • Grillot, D., Michel, M., Muller, I., Tougne, C., Renia, L., Mazier, D. et al. (1990). Immune responses to defined epitopes of the circumsporozoite protein of the murine malaria parasite, Plasmodium yoelii. Eur. J. Immunol., 30, 1215–122.
    • (1990) Eur. J. Immunol. , vol.30 , pp. 1215-2122
    • Grillot, D.1    Michel, M.2    Muller, I.3    Tougne, C.4    Renia, L.5    Mazier, D.6
  • 73
    • 0028884598 scopus 로고
    • Adjuvants for human vaccines — current status, problems and future prospects
    • Gupta, R.K. and Siber, G. (1995). Adjuvants for human vaccines — current status, problems and future prospects. Vaccine, 13, 1263–1276.
    • (1995) Vaccine , vol.13 , pp. 1263-1276
    • Gupta, R.K.1    Siber, G.2
  • 74
    • 0018565571 scopus 로고
    • Preliminary studies on vaccination of rhesus monkeys with irradiated sporozoites of plasmodium knowlesi and characterization of surface antigens of these parasites
    • Gwadz, R.W., Cochrane, A.H., Nussenzweig, V. and Nussenzweig, RS. (1979). Preliminary studies on vaccination of rhesus monkeys with irradiated sporozoites of Plasmodium knowlesi and characterization of surface antigens of these parasites. Bull. W.H.O., 57(Suppl.), 165–173.
    • (1979) Bull. W.H.O , vol.57 , pp. 165-173
    • Gwadz, R.W.1    Cochrane, A.H.2    Nussenzweig, V.3    Nussenzweig, R.S.4
  • 75
    • 0026735577 scopus 로고
    • Human recognition of T cell epitopes on the plasmodium vivax circumsp orozoite protein
    • Herrera, S., Escobar, P., de Plata, C., Avila, G.I., Corradin, G. and Herrera, M.A. (1992). Human recognition of T cell epitopes on the Plasmodium vivax circumsp orozoite protein. J. Imm unol., 148, 3986–3990.
    • (1992) J. Imm Unol. , vol.148 , pp. 3986-3990
    • Herrera, S.1    Escobar, P.2    De Plata, C.3    Avila, G.I.4    Corradin, G.5    Herrera, M.A.6
  • 76
    • 0030939515 scopus 로고    scopus 로고
    • Antigenicity and immunogenicity of multiple antigen peptides (Map) containing plasmodium vivax CS epitopes in aotus monkeys
    • Herrera, S., DePlata, C., Gonzalez, J.M., Perlaza, B.L., Bettens, P., Corradin, G. et al. (1997). Antigenicity and immunogenicity of multiple antigen peptides (MAP) containing Plasmodium vivax CS epitopes in Aotus monkeys. Parasite Imm unol., 19, 161–170.
    • (1997) Parasite Imm Unol. , vol.19 , pp. 161-170
    • Herrera, S.1    DePlata, C.2    Gonzalez, J.M.3    Perlaza, B.L.4    Bettens, P.5    Corradin, G.6
  • 77
    • 0023182064 scopus 로고
    • Safety and immunogenicity in man of a synthetic peptide malaria vaccine against plasmodiumfalciparum sporozoites
    • Herrington, D.A., Clyde, D.F., Losonsky, G., Cortesia, M., Murphy, J.R., Davis, J. et al. (1987). Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodiumfalciparum sporozoites. Nature. 328, 257–259.
    • (1987) Nature , vol.328 , pp. 257-259
    • Herrington, D.A.1    Clyde, D.F.2    Losonsky, G.3    Cortesia, M.4    Murphy, J.R.5    Davis, J.6
  • 78
    • 0025719101 scopus 로고
    • Successful immunization of humans with irradiated malaria sporozoites: Humoral and cellular responses of the protected individuals
    • Herrington, D., Davis, J., Nardin, E., Beier, M., Cortese, J., Eddy, H. et al. (1991). Successful immunization of humans with irradiated malaria sporozoites: Humoral and cellular responses of the protected individuals. Am. J. Trop. Med. Hyg., 45, 539–547.
    • (1991) Am. J. Trop. Med. Hyg. , vol.45 , pp. 539-547
    • Herrington, D.1    Davis, J.2    Nardin, E.3    Beier, M.4    Cortese, J.5    Eddy, H.6
  • 79
    • 0019222660 scopus 로고
    • Carrier priming leads to hapten specific suppression
    • Herzenberg, L.A., Tokuhisa, T. and Herzenberg, LA (1980). Carrier priming leads to hapten specific suppression. Nature, 285, 664–667.
    • (1980) Nature , vol.285 , pp. 664-667
    • Herzenberg, L.A.1    Tokuhisa, T.2    Herzenberg, L.A.3
  • 80
    • 0026471097 scopus 로고
    • Molecular analysis of the association of HLA-B53 and resistance to severe malaria
    • Hill, A.V., Elvin, J., Willis, AC., Aidoo, M., Allsopp, C.E., Gotch, F.M. et al. (1992). Molecular analysis of the association of HLA-B53 and resistance to severe malaria. Nature, 360, 434–439.
    • (1992) Nature , vol.360 , pp. 434-439
    • Hill, A.V.1    Elvin, J.2    Willis, A.C.3    Aidoo, M.4    Allsopp, C.E.5    Gotch, F.M.6
  • 81
    • 0029898025 scopus 로고    scopus 로고
    • Comparison of adjuvant formulations for cytotoxic T cell induction using synthetic peptides
    • Hioe, C.E., Qiu, H., Chend, P.D., Bian, Z., Li, M.-L., Li, J. et al. (1996). Comparison of adjuvant formulations for cytotoxic T cell induction using synthetic peptides. Vaccine, 14, 412–418.
    • (1996) Vaccine , vol.14 , pp. 412-418
    • Hioe, C.E.1    Qiu, H.2    Chend, P.D.3    Bian, Z.4    Li, M.-L.5    Li, J.6
  • 82
    • 0022509082 scopus 로고
    • Immunity to malaria and naturally acquired antibodies to the circumsporozoite protein of plasmodium falciparum
    • Hoffman S.L., Wi star, R., Ballou, WR., Hollingdale, M.R., Wirtz, R.A, Schneider, I. et al. (1986). Immunity to malaria and naturally acquired antibodies to the circumsporozoite protein of Plasmodium falciparum. New Eng. J. Med., 315, 601–606.
    • (1986) New Eng. J. Med. , vol.315 , pp. 601-606
    • Hoffman, S.L.1    Wi Star, R.2    Ballou, W.R.3    Hollingdale, M.R.4    Wirtz, R.A.5    Schneider, I.6
  • 83
    • 0024555887 scopus 로고
    • Human lymphocyte proliferative response to a sporozoite T cell epitope correlates with resistance to falciparum malaria
    • Hoffman, S. Oster, C., Mason, C., Beier, J., Sherwood, J., Ballou, W.R. et al. (1989). Human lymphocyte proliferative response to a sporozoite T cell epitope correlates with resistance to falciparum malaria. J. Immunol., 142, 1299–1303.
    • (1989) J. Immunol. , vol.142 , pp. 1299-1303
    • Hoffman, S.1    Oster, C.2    Mason, C.3    Beier, J.4    Sherwood, J.5    Ballou, W.R.6
  • 84
    • 0024413594 scopus 로고
    • Sporozoite vaccine induces genetically restricted T cell elimination of malaria from hepatocytes
    • Hoffman, S., Isenbarger, D., Long, G., Sedegah, M., Szarfman, A., Waters, L. et al. (1989). Sporozoite vaccine induces genetically restricted T cell elimination of malaria from hepatocytes. Science, 244, 1078–1081.
    • (1989) Science , vol.244 , pp. 1078-1081
    • Hoffman, S.1    Isenbarger, D.2    Long, G.3    Sedegah, M.4    Szarfman, A.5    Waters, L.6
  • 85
    • 0020026673 scopus 로고
    • Antibodies to the protective antigen of plasm odium berghei sporo zoites prevent entry into cultured hepatoma cells
    • Hollingdale, M.R., Zavala, F., Nussenzweig, R.S. and Nussenzweig, V (1982). Antibodies to the protective antigen of Plasm odium berghei sporo zoites prevent entry into cultured hepatoma cells. J. Immunol., 128, 1929–1930.
    • (1982) J. Immunol. , vol.128 , pp. 1929-1930
    • Hollingdale, M.R.1    Zavala, F.2    Nussenzweig, R.S.3    Nussenzweig, V.4
  • 86
    • 0021368476 scopus 로고
    • Inhibition of entry of plasmodiumfalciparum and p. Vivax sporozoites I nto cultured cells; an in vitro assay of protective antibodies
    • Hollingdale, M.R., Nardin, E.H., Tharavanij, S., Schwartz, AL. and Nussenzweig, R.S. (1984). Inhibition of entry of Plasmodiumfalciparum and P. vivax sporozoites I nto cultured cells; an in vitro assay of protective antibodies. J. Immunol., 132, 909–913.
    • (1984) J. Immunol. , vol.132 , pp. 909-913
    • Hollingdale, M.R.1    Nardin, E.H.2    Tharavanij, S.3    Schwartz, A.L.4    Nussenzweig, R.S.5
  • 87
    • 0026057983 scopus 로고
    • Protection against lethal sendai virus infection by in vivo priming of virus specific cytotoxic T lymphocytes with a free synthetic peptide
    • Kast, W.M., Roux, L., Curren, J., Blorn, H.J., Voordouw, A, C., Meloen, R.H. et al. (1991). Protection against lethal Sendai virus infection by in vivo priming of virus specific cytotoxic T lymphocytes with a free synthetic peptide. PNAS, 88, 2283–2287.
    • (1991) PNAS , vol.88 , pp. 2283-2287
    • Kast, W.M.1    Roux, L.2    Curren, J.3    Blorn, H.J.4    Meloen, R.H.5
  • 88
    • 0026033441 scopus 로고
    • Separation and characterization of saponins with adjuvant activity from quillaja saponaria molina cortex
    • Kensil, C.R., Patel, U., Lennick, M. and Marciani, D. (1991). Separation and characterization of saponins with adjuvant activity from Quillaja saponaria molina cortex. J. Immunol., 146, 431–437.
    • (1991) J. Immunol. , vol.146 , pp. 431-437
    • Kensil, C.R.1    Patel, U.2    Lennick, M.3    Marciani, D.4
  • 89
    • 0025739966 scopus 로고
    • Role of host cellular response in differential susceptibility of nonimmunized balb/c mice to plasmodium berghei and plasmodium yoelii sporozoites
    • Khan, A.M. and Vanderberg, J.P. (1991). Role of host cellular response in differential susceptibility of nonimmunized BALB/c mice to Plasmodium berghei and Plasmodium yoelii sporozoites. Infect. Immun., 59, 2529–2534.
    • (1991) Infect. Immun. , vol.59 , pp. 2529-2534
    • Khan, A.M.1    Vanderberg, J.P.2
  • 90
    • 0025817341 scopus 로고
    • Protection against malaria by vaccination with sporozoite surface protein 2 plus CS protein
    • Khusmith, S., Charoenvit, Y., Kumar, S., Sedegah, M., Beaudoin, R.L. and Hoffman, S.L. (1991). Protection against malaria by vaccination with sporozoite surface protein 2 plus CS protein. Science, 252, 715–718.
    • (1991) Science , vol.252 , pp. 715-718
    • Khusmith, S.1    Charoenvit, Y.2    Kumar, S.3    Sedegah, M.4    Beaudoin, R.L.5    Hoffman, S.L.6
  • 91
    • 0028236416 scopus 로고
    • Complete protection against plasmodium yoelii by adoptive transfer of CD8+ cytotoxic T cell clone recognizing sporozoite surface protein 2
    • Khusmith, S., Sedegah, M. and Hoffman, S.L. (1994). Complete protection against Plasmodium yoelii by adoptive transfer of CD8+ cytotoxic T cell clone recognizing sporozoite surface protein 2. Infect. Immun., 62, 2979–2983.
    • (1994) Infect. Immun. , vol.62 , pp. 2979-2983
    • Khusmith, S.1    Sedegah, M.2    Hoffman, S.L.3
  • 92
    • 0028914254 scopus 로고
    • Co-localization of inducible-nitric oxide synthase and plasmodium berghei in hepatocytes from rats immunized with irradiated sporozoites
    • Klotz, E, Scheller, L., Seguin, M., Kumar, N., Marietta, M.A., Green, SJ. et al. (1995). Co-localization of inducible-nitric oxide synthase and Plasmodium berghei in hepatocytes from rats immunized with irradiated sporozoites. J. Immunol., 154, 3391–3395.
    • (1995) J. Immunol. , vol.154 , pp. 3391-3395
    • Klotz, E.1    Scheller, L.2    Seguin, M.3    Kumar, N.4    Marietta, M.A.5    Green, S.J.6
  • 93
    • 0028910938 scopus 로고
    • A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules
    • Kovacsovics-Bankowski, M. and Rock, K.L. (1995). A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science, 267, 243–246.
    • (1995) Science , vol.267 , pp. 243-246
    • Kovacsovics-Bankowski, M.1    Rock, K.L.2
  • 94
    • 0029097457 scopus 로고
    • T lymphocytes from volunteers immunized with irradiated plasmodium falcip arum sporozoites recognize liver and blood stage malaria antigens
    • Krzych, U., Lyon, J.A., Jareed, T., Schneider, L, Hollingdale, M.R., Gordon, D.M. et al. (1995). T lymphocytes from volunteers immunized with irradiated Plasmodium falcip arum sporozoites recognize liver and blood stage malaria antigens. J. Immunol., 155, 4072–4077.
    • (1995) J. Immunol. , vol.155 , pp. 4072-4077
    • Krzych, U.1    Lyon, J.A.2    Jareed, T.3    Schneider, L.4    Hollingdale, M.R.5    Gordon, D.M.6
  • 95
    • 0023746601 scopus 로고
    • Cytotoxic T cells specific for the circumsporozoite protein of plasmodium falciparum
    • Kumar, S., Miller, L., Quakyi, I., Keister, D., Houghten, R., Maloy, W. et al. (1988). Cytotoxic T cells specific for the circumsporozoite protein of Plasmodium falciparum. Nature, 334, 258–260.
    • (1988) Nature , vol.334 , pp. 258-260
    • Kumar, S.1    Miller, L.2    Quakyi, I.3    Keister, D.4    Houghten, R.5    Maloy, W.6
  • 96
    • 0026515267 scopus 로고
    • Universal T helper cell determinants enhance immunogenicity of a plasmodium falcip arum merozoite surface antigen peptide
    • Kumar, A, Arora, R., Kaur, P., Chauhan, VS. and Sharma, P. (1992). “Universal” T helper cell determinants enhance immunogenicity of a Plasmodium falcip arum merozoite surface antigen peptide. J. Immunol., 148, 1499–1505.
    • (1992) J. Immunol. , vol.148 , pp. 1499-1505
    • Kumar, A.1    Arora, R.2    Kaur, P.3    Chauhan, V.S.4    Sharma, P.5
  • 97
    • 0023218259 scopus 로고
    • Structure of the gene encoding the circumsporozoite protein of plasmodium yoelii
    • A rodent model for examining antimalarial sporozoite vaccines
    • Lal, AA., de la Cruz, V.F., Welsh, J.A. Charoenvit, Y., Maloy, W.L. and McCutchan, T.F. (1987a). Structure of the gene encoding the circumsporozoite protein of Plasmodium yoelii. A rodent model for examining antimalarial sporozoite vaccines. J. Biol. Chem., 262, 2937–2940.
    • (1987) J. Biol. Chem. , vol.262 , pp. 2937-2940
    • Lal, A.A.1    De La Cruz, V.F.2    Welsh, J.A.3    Charoenvit, Y.4    Maloy, W.L.5    McCutchan, T.F.6
  • 98
    • 0023578885 scopus 로고
    • In vivo testing of subunit vaccine against malaria sporozoites using a rodent system
    • Lal, AA., de la Cruz, V.F., Good, M. Weiss, W.R., Lunde, M., Maloy, W.L. et al. (1987b). In vivo testing of subunit vaccine against malaria sporozoites using a rodent system. PNAS, 84, 8647–8651.
    • (1987) PNAS , vol.84 , pp. 8647-8651
    • Lal, A.A.1    De La Cruz, V.F.2    Good, M.3    Weiss, W.R.4    Lunde, M.5    Maloy, W.L.6
  • 99
    • 0025784381 scopus 로고
    • Circumsporozoite protein gene from plasmodium reichenowi, apfalciparum-like malaria parasite: An approach in the identification of epitopes for malaria vaccine development?
    • Lal, A.A. and Goldman, I.E (1991). Circumsporozoite protein gene from Plasmodium reichenowi, aPfalciparum-like malaria parasite: An approach in the identification of epitopes for malaria vaccine development? J. Biol. Chem., 266, 6686–6689.
    • (1991) J. Biol. Chem. , vol.266 , pp. 6686-6689
    • Lal, A.A.1    Goldman, I.E.2
  • 100
    • 0028271128 scopus 로고
    • First peptide vaccine providing protection against viral infection in the target animal: Studies of canine parvovirus in dogs
    • Langeveld, J.P., Casal, J.I, Osterhaus, A.D., Cortes, E., de Swart, R., Vela, C. et al. (1994). First peptide vaccine providing protection against viral infection in the target animal: studies of canine parvovirus in dogs. J. Virol., 68, 4506–4513.
    • (1994) J. Virol , vol.68 , pp. 4506-4513
    • Langeveld, J.P.1    Casal, J.I.2    Osterhaus, A.D.3    Cortes, E.4    De Swart, R.5    Vela, C.6
  • 101
    • 0029160392 scopus 로고
    • Full protection in mink against mink enteritis virus with new generation canine parvovirus vaccines based on synthetic peptide or recombinant protein
    • Langeveld, J.P., Kamstrup, S., Uttenthal, A, Strandbygaard, B., Vela, C., Dalsgaard, K et al. (1995). Full protection in mink against mink enteritis virus with new generation canine parvovirus vaccines based on synthetic peptide or recombinant protein. Vaccine, 13, 1033–1037.
    • (1995) Vaccine , vol.13 , pp. 1033-1037
    • Langeveld, J.P.1    Kamstrup, S.2    Uttenthal, A.3    Strandbygaard, B.4    Vela, C.5    Dalsgaard, K.6
  • 102
    • 0023000103 scopus 로고
    • A synthetic analogue of escherichia coli lipoprotein, tripalmitoyl pentapeptide, constitutes a potent immune adjuvant
    • Lex, A, Wiesmuller, K-H., Jung, G. and Bessler, W.G. (1986). A synthetic analogue of Escherichia coli lipoprotein, tripalmitoyl pentapeptide, constitutes a potent immune adjuvant. J. Immunol., 137, 2676–2681.
    • (1986) J. Immunol. , vol.137 , pp. 2676-2681
    • Lex, A.1    Wiesmuller, K.-H.2    Jung, G.3    Bessler, W.G.4
  • 103
    • 0027292880 scopus 로고
    • Priming with recombinant influenza virus followed by adminstration of recombinant vaccinia virus induces CD8+ T cell mediated protective immunity against malaria
    • Li, S., Rodrigues, M., Rodriguez, D., Rodriguez, J.R., Esteban, M., Palese, P. et al. (1993). Priming with recombinant influenza virus followed by adminstration of recombinant vaccinia virus induces CD8+ T cell mediated protective immunity against malaria. PNAS, 90, 5214–5218.
    • (1993) PNAS , vol.90 , pp. 5214-5218
    • Li, S.1    Rodrigues, M.2    Rodriguez, D.3    Rodriguez, J.R.4    Esteban, M.5    Palese, P.6
  • 104
    • 0031204408 scopus 로고    scopus 로고
    • The hepatitis b virus specific CTL responses induced in humans by lipopeptide vaccination are comparable to those elicited by acute viral infection
    • Livingston, B.D., Crimi, C., Grey, H., Ishioka, G., Chisari, F.V., Fikes, J. et al. (1997). The hepatitis B virus specific CTL responses induced in humans by lipopeptide vaccination are comparable to those elicited by acute viral infection. J. Immunol., 159, 1383–1392.
    • (1997) J. Immunol. , vol.159 , pp. 1383-1392
    • Livingston, B.D.1    Crimi, C.2    Grey, H.3    Ishioka, G.4    Chisari, F.V.5    Fikes, J.6
  • 105
    • 0024439987 scopus 로고
    • Wild isolates of plasmodium falciparum show extensive polymorphism in T cell epitopes of the circumsporozoite protein
    • Lockyer, M., Marsh, K and Newbold, C. (1989). Wild isolates of Plasmodium falciparum show extensive polymorphism in T cell epitopes of the circumsporozoite protein. Mol. Biochem. Parasitol., 37, 275–280.
    • (1989) Mol. Biochem. Parasitol. , vol.37 , pp. 275-280
    • Lockyer, M.1    Marsh, K.2    Newbold, C.3
  • 106
    • 0025061408 scopus 로고
    • Secondary structure and immunogenicity of hybrid synthetic peptides derived from two plasmodium falciparum pre-erythrocytic antigens
    • Londono, J.A., Gras-Masse, H., Dubeaux, C., Tartar, A. and Druilhe, P. (1990). Secondary structure and immunogenicity of hybrid synthetic peptides derived from two Plasmodium falciparum pre-erythrocytic antigens. J. Immunol., 145, 1557–1563.
    • (1990) J. Immunol. , vol.145 , pp. 1557-1563
    • Londono, J.A.1    Gras-Masse, H.2    Dubeaux, C.3    Tartar, A.4    Druilhe, P.5
  • 107
    • 0023943993 scopus 로고
    • Proteosome-lipopeptide vaccines: Enhancement of immunogenicity for malaria CS peptides
    • Lowell, G.H., Ballou, W.R Smith, L.F, Wirtz, RA., Zollinger, W.D. and Hockmeyer, W.T. (1988). Proteosome-lipopeptide vaccines: Enhancement of immunogenicity for malaria CS peptides. Science, 240, 800–802.
    • (1988) Science , vol.240 , pp. 800-802
    • Lowell, G.H.1    Ballou, W.R.2    Smith, L.F.3    Wirtz, R.A.4    Zollinger, W.D.5    Hockmeyer, W.T.6
  • 108
    • 0026329874 scopus 로고
    • Human cytotoxic T lymphocytes against the plasmodium falciparum circumsporozoite protein
    • Malik, A., Egan, J.E., Houghten, R.A., Sadoff, J.C. and Hoffman, S.L. (1991). Human cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein. PNAS, 88, 3300–3304.
    • (1991) PNAS , vol.88 , pp. 3300-3304
    • Malik, A.1    Egan, J.E.2    Houghten, R.A.3    Sadoff, J.C.4    Hoffman, S.L.5
  • 110
    • 0017345706 scopus 로고
    • Plasmodium vivax: Correlation of circumsporozoite precipitation (CSP)
    • reaction with sporozoite-induced protective immunity in man
    • McCarthy, V.C. and Clyde, D.F (1977). Plasmodium vivax: Correlation of circumsporozoite precipitation (CSP). reaction with sporozoite-induced protective immunity in man. Exp. Parasitol., 41, 167–171.
    • (1977) Exp. Parasitol. , vol.41 , pp. 167-171
    • McCarthy, V.C.1    Clyde, D.F.2
  • 111
    • 0029969113 scopus 로고    scopus 로고
    • Comparison of circumsporozoite proteins from avian and mammalian malarias: Biological and phylogenetic implications
    • McCutchan, T.F, Kissinger, J.C., Touray, M.G., Rogers, M.J., Li, J., Sullivan, M. et al. (1996). Comparison of circumsporozoite proteins from avian and mammalian malarias: biological and phylogenetic implications. PNAS, 93, 11889–11894.
    • (1996) PNAS , vol.93 , pp. 11889-11894
    • McCutchan, T.F.1    Kissinger, J.C.2    Touray, M.G.3    Rogers, M.J.4    Li, J.5    Sullivan, M.6
  • 112
    • 0025349375 scopus 로고
    • Protection against malaria induced by irradiated sporozoites
    • Mellouk, S., Lunel, F, Sedegah, M., Beaudoin, R.L. and Druilhe, P. (1990). Protection against malaria induced by irradiated sporozoites. Lancet, 335, 721.
    • (1990) Lancet , vol.335 , pp. 721
    • Mellouk, S.1    Lunel, F.2    Sedegah, M.3    Beaudoin, R.L.4    Druilhe, P.5
  • 113
    • 0025761982 scopus 로고
    • Ifn gamma inhibits development of plasmodium berghei exoerythrocytic stages in hepatocytes by an l-arginine-dependent effector mechanism
    • Mellouk, S., Green, S., Nacy, C. and Hoffman, S. (1991). IFN gamma inhibits development of Plasmodium berghei exoerythrocytic stages in hepatocytes by an L-arginine-dependent effector mechanism. J. Immunol., 146, 3971–3976.
    • (1991) J. Immunol. , vol.146 , pp. 3971-3976
    • Mellouk, S.1    Green, S.2    Nacy, C.3    Hoffman, S.4
  • 114
    • 0030459553 scopus 로고    scopus 로고
    • Induction of sustained and elevated immune responses to weakly immunogenic synthetic malarial peptides by encapsulation in biodegradable polymer microspheres
    • Men, Y., Gander, B., Merkle H. and Corradin, G. (1996). Induction of sustained and elevated immune responses to weakly immunogenic synthetic malarial peptides by encapsulation in biodegradable polymer microspheres. Vaccine, 14, 1442–1450.
    • (1996) Vaccine , vol.14 , pp. 1442-1450
    • Men, Y.1    Gander, B.2    Merkle, H.3    Corradin, G.4
  • 115
    • 0342350727 scopus 로고    scopus 로고
    • Circumsporozoite protein is required for development of malaria sporozoites in mosquitoes
    • Menard, R, Sultan, A.A., Cortes, C., Altszuler, R, van Dijk, M.R, Janse, C.J. et al. (1997). Circumsporozoite protein is required for development of malaria sporozoites in mosquitoes. Nature, 385, 336–340.
    • (1997) Nature , vol.385 , pp. 336-340
    • Menard, R.1    Sultan, A.A.2    Cortes, C.3    Altszuler, R.4    Van Dijk, M.R.5    Janse, C.J.6
  • 116
    • 20744456789 scopus 로고
    • Solid-phase peptide synthesis. The synthesis of a tetrapeptide
    • Merrifield, RB. (1963). Solid-phase peptide synthesis. The synthesis of a tetrapeptide. J. Am. Chem. Soc., 85, 2149–2455.
    • (1963) J. Am. Chem. Soc. , vol.85 , pp. 2149-2455
    • Merrifield, R.B.1
  • 118
    • 0027398768 scopus 로고
    • Malaria vaccine: Immunization of mice with a synthetic T cell helper epitope alone leads to protective immunity
    • Migliorini, P., Betschart, B. and Corradin, G. (1993). Malaria vaccine: immunization of mice with a synthetic T cell helper epitope alone leads to protective immunity. Eur. J. Immunol., 23, 582–585.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 582-585
    • Migliorini, P.1    Betschart, B.2    Corradin, G.3
  • 119
    • 0031572504 scopus 로고    scopus 로고
    • A synthetic peptide administered with il-12 elicits immunity to listeria monocytogenes
    • Miller, M.A., Skeen, M.J. and Ziegler, H.K (1997). A synthetic peptide administered with IL-12 elicits immunity to Listeria monocytogenes. J. Immunol., 159, 3675–3679.
    • (1997) J. Immunol. , vol.159 , pp. 3675-3679
    • Miller, M.A.1    Skeen, M.J.2    Ziegler, H.K.3
  • 120
    • 0026040932 scopus 로고
    • Cytotoxic CD4+ T cells from a sporozoite immunized volunteer recognize the plasmodium falciparum CS protein
    • Moreno, A., Clavijo, P., Edelman, R, Davis, J., Sztein, M., Herrington, D. and Nardin, E. (1991). Cytotoxic CD4+ T cells from a sporozoite immunized volunteer recognize the Plasmodium falciparum CS protein. Int. Immunol., 3, 997–1003.
    • (1991) Int. Immunol. , vol.3 , pp. 997-1003
    • Moreno, A.1    Clavijo, P.2    Edelman, R.3    Davis, J.4    Sztein, M.5    Herrington, D.6    Nardin, E.7
  • 121
    • 0027171406 scopus 로고
    • Cd4+ T cell clones obtained from plasmodiumfalciparum sporozoite-immunized volunteers recognize polymorphic sequences of the circumsporozoite protein
    • Moreno, A, Clavijo, P., Edelman, R, Davis, J., Sztein, M., Sinigaglia, F et al. (1993). CD4+ T cell clones obtained from Plasmodiumfalciparum sporozoite-immunized volunteers recognize polymorphic sequences of the circumsporozoite protein. J. Immunol., 151, 489–499.
    • (1993) J. Immunol. , vol.151 , pp. 489-499
    • Moreno, A.1    Clavijo, P.2    Edelman, R.3    Davis, J.4    Sztein, M.5    Sinigaglia, F.6
  • 123
    • 0028979830 scopus 로고
    • Induction of antigen-specific cytolytic T cells in situ in human melanoma by immunization with synthetic peptide-pulsed autologous antigen presenting cells
    • Mukherji, B., Chakraborty, N.G., Yamasaki, S., Okino, T., Yamase, H., Sporn, J.R. et al. (1995). Induction of antigen-specific cytolytic T cells in situ in human melanoma by immunization with synthetic peptide-pulsed autologous antigen presenting cells. PNAS, 92, 8078–8082.
    • (1995) PNAS , vol.92 , pp. 8078-8082
    • Mukherji, B.1    Chakraborty, N.G.2    Yamasaki, S.3    Okino, T.4    Yamase, H.5    Sporn, J.R.6
  • 124
    • 0027326632 scopus 로고
    • Thrombospondin related anonymous protein (TRAP) ofplasmodiumfalciparum binds specifically to sulphated glycoconjugates and to hep g2 hepatoma cells, suggesting a role for this molecule in sporozoite invasion of hepatocytes
    • Muller, H.M., Reckman, I., Hollingdale, M., Bujard, H., Robson, K. and Crisanti, A (1993). Thrombospondin related anonymous protein (TRAP) ofPlasmodiumfalciparum binds specifically to sulphated glycoconjugates and to Hep G2 hepatoma cells, suggesting a role for this molecule in sporozoite invasion of hepatocytes. EMBO J., 12, 2881–2889.
    • (1993) EMBO J , vol.12 , pp. 2881-2889
    • Muller, H.M.1    Reckman, I.2    Hollingdale, M.3    Bujard, H.4    Robson, K.5    Crisanti, A.6
  • 125
    • 0026003043 scopus 로고
    • Immunogenicity of multiple antigen peptides (Map) containing T and b cell epitopes of the repeat region of the plasmodium falciparum circumsporozoite protein
    • Munesinghe, D.Y., Clavijo, P., Calvo-Calle, J.M., Nussenzweig, RS. and Nardin, E. (1991). Immunogenicity of multiple antigen peptides (MAP) containing T and B cell epitopes of the repeat region of the Plasmodium falciparum circumsporozoite protein. Eur. J. Immunol., 21, 3015–3020.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 3015-3020
    • Munesinghe, D.Y.1    Clavijo, P.2    Calvo-Calle, J.M.3    Nussenzweig, R.S.4    Nardin, E.5
  • 127
    • 0028139189 scopus 로고
    • Oral adminstration of an antigenic synthetic lipopeptide (Map-p3c) evokes salivary antibodies and systemic humoral and cellular responses
    • Nardelli, B., Haser, P.B. and Tam, J.P. (1994). Oral adminstration of an antigenic synthetic lipopeptide (MAP-P3C) evokes salivary antibodies and systemic humoral and cellular responses. Vaccine, 12, 1335–1339.
    • (1994) Vaccine , vol.12 , pp. 1335-1339
    • Nardelli, B.1    Haser, P.B.2    Tam, J.P.3
  • 128
    • 0018580703 scopus 로고
    • Antibodies to sporozoites: Their frequent occurrence in individuals living in an area of hyperendemic malaria
    • Nardin, E.H., Nussenzweig, RS., McGregor, I.A and Bryan, J.H. (1979). Antibodies to sporozoites: their frequent occurrence in individuals living in an area of hyperendemic malaria. Science, 206, 597–599.
    • (1979) Science , vol.206 , pp. 597-599
    • Nardin, E.H.1    Nussenzweig, R.S.2    McGregor, I.A.3    Bryan, J.H.4
  • 130
    • 0026025963 scopus 로고
    • T cell epitopes of the circumsporozoite protein of plasmodium vivax: Recognition by lymphocytes of a sporozoite immunized chimpanzee
    • Nardin, E.H., Clavijo, P., Mons, B., van Belkum, A., Ponnudurai, T. and Nussenzweig, R. (1991). T cell epitopes of the circumsporozoite protein of Plasmodium vivax: Recognition by lymphocytes of a sporozoite immunized chimpanzee. J. Immunol., 146, 1674–1678.
    • (1991) J. Immunol. , vol.146 , pp. 1674-1678
    • Nardin, E.H.1    Clavijo, P.2    Mons, B.3    Van Belkum, A.4    Ponnudurai, T.5    Nussenzweig, R.6
  • 131
    • 0024819071 scopus 로고
    • Conserved repetitive epitope recognized by CD4+ clones from a malaria-immunized volunteer
    • Nardin, E.H., Herrington, D.A., Davis, J., Levine, M., Stuber, D., Takacs, B. et al. (1989). Conserved repetitive epitope recognized by CD4+ clones from a malaria-immunized volunteer. Science, 246, 1603–1606.
    • (1989) Science , vol.246 , pp. 1603-1606
    • Nardin, E.H.1    Herrington, D.A.2    Davis, J.3    Levine, M.4    Stuber, D.5    Takacs, B.6
  • 132
    • 0028856566 scopus 로고
    • The use of multiple antigen peptides in the analysis and induction of protective immune responses against infectious diseases
    • Nardin, E.H., Oliveira, G.A, Calvo-Calle, J.M. and Nussenzweig, R. (1995). The use of multiple antigen peptides in the analysis and induction of protective immune responses against infectious diseases. Adv. Immunol., 60, 105–149.
    • (1995) Adv. Immunol. , vol.60 , pp. 105-149
    • Nardin, E.H.1    Oliveira, G.A.2    Calvo-Calle, J.M.3    Nussenzweig, R.4
  • 133
    • 0032053462 scopus 로고    scopus 로고
    • Plasmodium falciparum polyoximes: Highly immunogenic synthetic vaccines constructed by chemoselective ligation of repeat B-cell epitopes and a universal T-cell epitope of CS protein
    • Nardin, E.H., Calvo-Calle, J.M., Oliveira, G.A, Clavijo, P., Nussenzweig, RS., Simon, R, Zeng, W. and Rose, K. (1998). Plasmodium falciparum polyoximes: highly immunogenic synthetic vaccines constructed by chemoselective ligation of repeat B-cell epitopes and a universal T-cell epitope of CS protein. Vaccine, 16, 590–599.
    • (1998) Vaccine , vol.16 , pp. 590-599
    • Nardin, E.H.1    Calvo-Calle, J.M.2    Oliveira, G.A.3    Clavijo, P.4    Nussenzweig, R.S.5    Simon, R.6    Zeng, W.7    Rose, K.8
  • 135
    • 0001552479 scopus 로고    scopus 로고
    • Synthetic peptides entrapped in microparticles can elicit cytotoxic T cell activity
    • Nixon, D.F., Hioe, C., Chen, P.-D., Bian, X., Kueblers, P., Li, M.L. et al. (1996). Synthetic peptides entrapped in microparticles can elicit cytotoxic T cell activity. Vaccine, 14, 1523–1530.
    • (1996) Vaccine , vol.14 , pp. 1523-1530
    • Nixon, D.F.1    Hioe, C.2    Chen, P.-D.3    Bian, X.4    Kueblers, P.5    Li, M.L.6
  • 137
    • 0014202885 scopus 로고
    • Protective immunity produced by the injection of X-irradiated sporozoites of plasmodium berghei
    • Nussenzweig, RS., Vanderberg, J., Most, H. and Orton, C. (1967). Protective immunity produced by the injection of X-irradiated sporozoites of Plasmodium berghei. Nature, 216, 160–162.
    • (1967) Nature , vol.216 , pp. 160-162
    • Nussenzweig, R.S.1    Vanderberg, J.2    Most, H.3    Orton, C.4
  • 138
    • 0014576950 scopus 로고
    • Protective immunity produced by the injection of X-irradiated sporozoites of plasmodium berghei. IV. Dose response, specificity and humoral immunity
    • Nussenzweig, R, Vanderberg, J. and Most, H. (1969). Protective immunity produced by the injection of X-irradiated sporozoites of Plasmodium berghei. IV. Dose response, specificity and humoral immunity. Milit. Med., 134, 1176–1182.
    • (1969) Milit. Med. , vol.134 , pp. 1176-1182
    • Nussenzweig, R.1    Vanderberg, J.2    Most, H.3
  • 139
    • 0024312642 scopus 로고
    • Rationale for the development of an engineered sporozoite malaria vaccine
    • Nussenzweig, V. and Nussenzweig, RS. (1989). Rationale for the development of an engineered sporozoite malaria vaccine. Adv. Immunol., 45, 283–334.
    • (1989) Adv. Immunol. , vol.45 , pp. 283-334
    • Nussenzweig, V.1    Nussenzweig, R.S.2
  • 140
    • 0026065305 scopus 로고
    • L-arginine dependent destruction of intrahepatic malaria parasites in response to tumor necrosis factor and/or interleukin 6 stimulation
    • Nussler, A., Drapier, J.C., Renia, L., Pied, S., Miltgen, F., Gentilini, M. et al. (1991). L-Arginine dependent destruction of intrahepatic malaria parasites in response to tumor necrosis factor and/or interleukin 6 stimulation. Eur. J. Immunol., 21, 227–230.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 227-230
    • Nussler, A.1    Drapier, J.C.2    Renia, L.3    Pied, S.4    Miltgen, F.5    Gentilini, M.6
  • 141
    • 0028888304 scopus 로고
    • Reversible contraception in female baboons immunized with a synthetic epitope of sperm specific lactate dehydrogenase
    • O'Hern, P.A., Bambra, D.S., Isahakia, M. and Goldberg, E. (1995). Reversible contraception in female baboons immunized with a synthetic epitope of sperm specific lactate dehydrogenase. Biol. Reprod., 52, 331–339.
    • (1995) Biol. Reprod. , vol.52 , pp. 331-339
    • O'Hern, P.A.1    Bambra, D.S.2    Isahakia, M.3    Goldberg, E.4
  • 142
    • 0020010422 scopus 로고
    • Comparative studies on the immunogenicity of infective and attenuated sporozoites of plasmodium berghei
    • Orjih, AU., Cochrane, AH. and Nussenzweig, RS. (1982). Comparative studies on the immunogenicity of infective and attenuated sporozoites of Plasmodium berghei. Trans. Roy. Soc. Trap. Med. Hyg., 76, 5761.
    • (1982) Trans. Roy. Soc. Trap. Med. Hyg. , vol.76 , pp. 5761
    • Orjih, A.U.1    Cochrane, A.H.2    Nussenzweig, R.S.3
  • 143
    • 0024796883 scopus 로고
    • Universally immunogenic T cell epitopes: Promiscuous binding to human MHC class ii and promiscuous recognition by T cells
    • Panina-Bordignon, P., Tan, A, Termijtelen, A, Demotz, S., Corradin, G. and Lanzavecchia, A. (1989). Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells. Eur. J. Immunol., 19, 2237–2242.
    • (1989) Eur. J. Immunol. , vol.19 , pp. 2237-2242
    • Panina-Bordignon, P.1    Tan, A.2    Termijtelen, A.3    Demotz, S.4    Corradin, G.5    Lanzavecchia, A.6
  • 144
    • 0025789024 scopus 로고
    • Lack ofh-2 restriction of the plasmodium falciparum (Nanp) sequence as multiple antigen peptide
    • Pessi, A, Valmori, D., Migliorini, P., Tougne, C., Bianchi, E., Lambert, P. H. et al. (1991). Lack ofH-2 restriction of the Plasmodium falciparum (NANP) sequence as multiple antigen peptide. Eur. J. Immunol., 21, 2273–2276.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2273-2276
    • Pessi, A.1    Valmori, D.2    Migliorini, P.3    Tougne, C.4    Bianchi, E.5    Lambert, P.H.6
  • 145
    • 0026527135 scopus 로고    scopus 로고
    • Gentilini, m et al. (1992). 11–6, induced by ill, inhibits malaria pre-erythrocytic stages, but its secretion is down regulated by the parasite
    • Pied, S., Civas, A, Berlot-Picard, E, Renia, L., Miltgen, E, Gentilini, M et al. (1992). 11–6, induced by ILl, inhibits malaria pre-erythrocytic stages, but its secretion is down regulated by the parasite. J. Immunol., 148, 197–201.
    • J. Immunol. , vol.148 , pp. 197-201
    • Pied, S.1    Civas, A.2    Berlot-Picard, E.3    Renia, L.4    Miltgen, E.5
  • 147
    • 0018887685 scopus 로고
    • Monovalent fragments (Fab) of monoclonal antibodies to a sporozoite surface antigen (pb44) protect mice against malaria infection
    • Potocnjak, P., Yoshida, N., Nussenzweig, R.S. and Nussenzweig, V. (1980). Monovalent fragments (Fab) of monoclonal antibodies to a sporozoite surface antigen (Pb44) protect mice against malaria infection. J. Exp. Med., 151, 1504–1513.
    • (1980) J. Exp. Med. , vol.151 , pp. 1504-1513
    • Potocnjak, P.1    Yoshida, N.2    Nussenzweig, R.S.3    Nussenzweig, V.4
  • 148
    • 0025949444 scopus 로고
    • Wide distribution of the variant form of the human malaria parasite plasmodium vivax
    • Qari, S.H., Goldman, I.E, Povoa, MM., Oliveira, S., Alpers, M.P. and Lal, AA. (1991). Wide distribution of the variant form of the human malaria parasite Plasmodium vivax. J. Biol. Chem., 266, 16297–16300.
    • (1991) J. Biol. Chem. , vol.266 , pp. 16297-16300
    • Qari, S.H.1    Goldman, I.E.2    Povoa, M.M.3    Oliveira, S.4    Alpers, M.P.5    Lal, A.A.6
  • 149
    • 0031570937 scopus 로고    scopus 로고
    • Different modes of peptide interaction enable hla-dq and hla-dr molecules to bind diverse peptide repertoires
    • Raddrizzani, L., Sturniolo, T, Guenot, J. Bono, E., Gallazzi, P., Nagy, Z.A et al. (1997). Different modes of peptide interaction enable HLA-DQ and HLA-DR molecules to bind diverse peptide repertoires. J. Immunol., 159, 703–711.
    • (1997) J. Immunol. , vol.159 , pp. 703-711
    • Raddrizzani, L.1    Sturniolo, T.2    Guenot, J.3    Bono, E.4    Gallazzi, P.5    Nagy, Z.A.6
  • 150
    • 0028925869 scopus 로고
    • Antibody and clinical responses in volunteers to immunization with malaria peptide-diptheria toxoid conjugates
    • Ramasamy, R., Wijesundere, D.A., Nagendran, K. and Ramasamy, M.S. (1995). Antibody and clinical responses in volunteers to immunization with malaria peptide-diptheria toxoid conjugates. Clin. Exp. Immunol., 99, 168–174.
    • (1995) Clin. Exp. Immunol. , vol.99 , pp. 168-174
    • Ramasamy, R.1    Wijesundere, D.A.2    Nagendran, K.3    Ramasamy, M.S.4
  • 151
    • 0030175930 scopus 로고    scopus 로고
    • Re-investigation of the circumsporozoite protein based induction of sterile immunity against plasmodium berghei infection
    • Reed, R.C., Louis-Wileman, V., Wells, R.L., Verheul, A.M., Hunter, R.L. and Lal, A.A. (1996). Re-investigation of the circumsporozoite protein based induction of sterile immunity against Plasmodium berghei infection. Vaccine, 14, 828–836.
    • (1996) Vaccine , vol.14 , pp. 828-836
    • Reed, R.C.1    Louis-Wileman, V.2    Wells, R.L.3    Verheul, A.M.4    Hunter, R.L.5    Lal, A.A.6
  • 152
    • 0018593563 scopus 로고
    • Use of attenuated sporozoites in the immunization of human volunteers against falciparum malaria
    • Reickmann, K.H., Beaudoin, R.L., Cassells, J. and Sell, K. (1979). Use of attenuated sporozoites in the immunization of human volunteers against falciparum malaria. Bull. WHO, 57. Suppl I, 261–265.
    • (1979) Bull. WHO , vol.57 , pp. 261-265
    • Reickmann, K.H.1    Beaudoin, R.L.2    Cassells, J.3    Sell, K.4
  • 153
    • 0029072487 scopus 로고
    • Cd8+ T cell protective immunity induced by immunization with plasmodium berghei CS protein-derived synthetic peptides: Evidence that localization of peptide-specific ctls is crucial for protection against malaria
    • Renggli, J., Valmori, D., Romero, J.F., Eberl, G., Romero, P., Betschart, B. et al. (1995). CD8+ T cell protective immunity induced by immunization with Plasmodium berghei CS protein-derived synthetic peptides: evidence that localization of peptide-specific CTLs is crucial for protection against malaria. Immunol. Lett. 46, 199–205.
    • (1995) Immunol. Lett. , vol.46 , pp. 199-205
    • Renggli, J.1    Valmori, D.2    Romero, J.F.3    Eberl, G.4    Romero, P.5    Betschart, B.6
  • 154
    • 0025743461 scopus 로고
    • In vitro activity of CD4+ and CD8+ T lymphocytes from mice immunized with a synthetic malaria peptide
    • Renia, L., Marussig, M.S., Grillot, D., Pied, S., Corradin, G., Miltgen, F. et al. (1991). In vitro activity of CD4+ and CD8+ T lymphocytes from mice immunized with a synthetic malaria peptide. PNAS, 88, 7963–7967.
    • (1991) PNAS , vol.88 , pp. 7963-7967
    • Renia, L.1    Marussig, M.S.2    Grillot, D.3    Pied, S.4    Corradin, G.5    Miltgen, F.6
  • 155
    • 0027269630 scopus 로고
    • Effector functions of circumsporozoite peptide-primed CD4+ T cell clones against plasmodium yoelii liver stages
    • Renia, L., Grillot, D., Marussig, M., Corradin, G., Miltgen, E, Lambert, P. et al. (1993). Effector functions of circumsporozoite peptide-primed CD4+ T cell clones against Plasmodium yoelii liver stages. J. Immunol., 150, 1471–1478.
    • (1993) J. Immunol. , vol.150 , pp. 1471-1478
    • Renia, L.1    Grillot, D.2    Marussig, M.3    Corradin, G.4    Miltgen, E.5    Lambert, P.6
  • 156
    • 0030294648 scopus 로고    scopus 로고
    • Immunotherapy of cancer by peptide based vaccines for the induction of tumor specific T cell immunity
    • Ressing, M.E., Offringa, R., Toes, R.E.M., Ossendorp, E, de Jong, J.H., Brandt, R.M.P. et al. (1996). Immunotherapy of cancer by peptide based vaccines for the induction of tumor specific T cell immunity. Immunotech., 2, 241–251.
    • (1996) Immunotech , vol.2 , pp. 241-251
    • Ressing, M.E.1    Offringa, R.2    Toes, R.E.M.3    Ossendorp, E.4    De Jong, J.H.5    Brandt, R.M.P.6
  • 157
    • 0028155750 scopus 로고
    • T and b epitope determination and analysis of multiple antigenic peptides for the schistosoma mansoni experimental vaccine triose-phosphate isomerase
    • Reynolds, S.R., Dahl, C.E. and Ham, D.A. (1994). T and B epitope determination and analysis of multiple antigenic peptides for the Schistosoma mansoni experimental vaccine triose-phosphate isomerase. J. Immunol., 152, 193–200.
    • (1994) J. Immunol. , vol.152 , pp. 193-200
    • Reynolds, S.R.1    Dahl, C.E.2    Ham, D.A.3
  • 158
    • 0031568403 scopus 로고    scopus 로고
    • Protective monoclonal antibody defines a circumsporozoite-like glycoprotein exoantigen of cryptosporidium parvum sporozoites and merozoites
    • Riggs, M.W., Stone, AL., Yount, P.A., Langer, R.C., Arrowood, M.J. and Bentley, D.L. (1997). Protective monoclonal antibody defines a circumsporozoite-like glycoprotein exoantigen of Cryptosporidium parvum sporozoites and merozoites. J. Immunol., 158, 1787–1795.
    • (1997) J. Immunol. , vol.158 , pp. 1787-1795
    • Riggs, M.W.1    Stone, A.L.2    Yount, P.A.3    Langer, R.C.4    Arrowood, M.J.5    Bentley, D.L.6
  • 159
    • 0025131379 scopus 로고
    • Recognition of dominant T cell-stimulating epitopes from the circumsporozoite protein of plasmodium falciparum and relationship to malaria morbidity in gambian children
    • Riley, E., Allen, S., Bennett, S., Thomas, P., O’Donnell, A, Lindsay, S. et al. (1990), Recognition of dominant T cell-stimulating epitopes from the circumsporozoite protein of Plasmodium falciparum and relationship to malaria morbidity in Gambian children. Trans. Roy. Soc, of Trop. Med. Hyg., 84, 648–57.
    • (1990) Trans. Roy. Soc, of Trop. Med. Hyg. , vol.84 , pp. 648-657
    • Riley, E.1    Allen, S.2    Bennett, S.3    Thomas, P.4    O’Donnell, A.5    Lindsay, S.6
  • 160
    • 0026713712 scopus 로고
    • Construction of synthetic immunogens: Use of T- and B-cell epitopes of CS and resa proteins of plasmodium falciparum
    • Ritu, G. and Rao, D.N. (1992). Construction of synthetic immunogens: Use of T- and B-cell epitopes of CS and RESA proteins of Plasmodium falciparum. Vaccine, 10, 761–765.
    • (1992) Vaccine , vol.10 , pp. 761-765
    • Ritu, G.1    Rao, D.N.2
  • 161
    • 0023741661 scopus 로고
    • A highly conserved amino-acid sequence in thrombospondin, properdin and in proteins from sporozoites and blood stages of a human malaria parasite
    • Robson, K.J.H., Hall, J.R.S., Jennings, M.W., Harris, T.J.R., Marsh, K., Newbold, C. I. et al. (1988). A highly conserved amino-acid sequence in thrombospondin, properdin and in proteins from sporozoites and blood stages of a human malaria parasite. Nature, 335, 79–82.
    • (1988) Nature , vol.335 , pp. 79-82
    • Robson, K.J.H.1    Hall, J.R.S.2    Jennings, M.W.3    Harris, T.J.R.4    Marsh, K.5    Newbold, C.I.6
  • 163
    • 0029091846 scopus 로고
    • Thrombospondin-related adhesive protein (TRAP) of plasmodium falciparum: Expression during sporozoite ontogeny and binding to human hepatocytes
    • Robson, K. J., Frevert, U., Reckman, I., Cowan, G., Beier, J., Scragg, I.G. et al. (1995). Thrombospondin-related adhesive protein (TRAP) of Plasmodium falciparum: expression during sporozoite ontogeny and binding to human hepatocytes. EMBO J., 14, 3883–3894.
    • (1995) EMBO J , vol.14 , pp. 3883-3894
    • Robson, K.J.1    Frevert, U.2    Reckman, I.3    Cowan, G.4    Beier, J.5    Scragg, I.G.6
  • 164
    • 0031065201 scopus 로고    scopus 로고
    • Single immunizing dose of recombinant adenovirus efficiently induces CD8+ T cell mediated protective immunity against malaria
    • Rodrigues, E.G., Zavala, E, Eichinger, D., Wilson, J.M. and Tsuji, M. (1997). Single immunizing dose of recombinant Adenovirus efficiently induces CD8+ T cell mediated protective immunity against malaria, J. Immunol., 158, 1268–1274.
    • (1997) J. Immunol. , vol.158 , pp. 1268-1274
    • Rodrigues, E.G.1    Zavala, E.2    Eichinger, D.3    Wilson, J.M.4    Tsuji, M.5
  • 165
    • 0025783201 scopus 로고
    • Cd8+ cytolytic T cell clones derived against the plasmodium yoelii circumsporozoite protein protect against malaria
    • Rodrigues, M.M., Cordey, A.S., Arreaza, G., Corradin, G., Romero, P., Maryanski, J.L. et al. (1991). CD8+ cytolytic T cell clones derived against the Plasmodium yoelii circumsporozoite protein protect against malaria. Int. Immunol., 3, 579–585.
    • (1991) Int. Immunol. , vol.3 , pp. 579-585
    • Rodrigues, M.M.1    Cordey, A.S.2    Arreaza, G.3    Corradin, G.4    Romero, P.5    Maryanski, J.L.6
  • 166
    • 0026521962 scopus 로고
    • The in vivo cytotoxic activity of CD8+ T cell clones correlates with their levels of expression of adhesion molecules
    • Rodrigues, M., Nussenzweig, R, Romero, P. and Zavala, F. (1992). The in vivo cytotoxic activity of CD8+ T cell clones correlates with their levels of expression of adhesion molecules. J. Exp. Med., 175, 895–905.
    • (1992) J. Exp. Med. , vol.175 , pp. 895-905
    • Rodrigues, M.1    Nussenzweig, R.2    Romero, P.3    Zavala, F.4
  • 167
    • 0027361805 scopus 로고
    • The relative contribution of antibodies, CD4+ and CD8+ T cells to sprozoite induced protection against malaria
    • Rodrigues, M., Nussenzweig, RS. and Zavala, F. (1993). The relative contribution of antibodies, CD4+ and CD8+ T cells to sprozoite induced protection against malaria. Immunology, 80, 1–5.
    • (1993) Immunology , vol.80 , pp. 1-5
    • Rodrigues, M.1    Nussenzweig, R.S.2    Zavala, F.3
  • 168
    • 0026757766 scopus 로고
    • Characterization of plasmodiumjalciparum sporozoite surface protein 2
    • Rogers, w., Malik, A., Mellouk, A., Nakamura, K., Rogers, M.D., Szarfman, A. et al. (1992). Characterization of PlasmodiumJalciparum sporozoite surface protein 2. PNAS, 89, 9176–9180.
    • (1992) PNAS , vol.89 , pp. 9176-9180
    • Rogers, W.1    Malik, A.2    Mellouk, A.3    Nakamura, K.4    Rogers, M.D.5    Szarfman, A.6
  • 169
    • 0024954612 scopus 로고
    • Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria
    • Romero, P., Maryanski, J.L., Corradin, G., Nussenzweig, RS., Nussenzweig, V. and Zavala, F. (1989). Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria. Nature, 341, 323–326.
    • (1989) Nature , vol.341 , pp. 323-326
    • Romero, P.1    Maryanski, J.L.2    Corradin, G.3    Nussenzweig, R.S.4    Nussenzweig, V.5    Zavala, F.6
  • 170
    • 0026555614 scopus 로고
    • Immunization with synthetic peptides containing a defined malaria epitope induces a highly diverse cytotoxic T lymphocyte response
    • Romero, P., Eberl, G., Casanova, J.L., Cordey, AS., Widmann, C., Luescher, I. et al. (1992). Immunization with synthetic peptides containing a defined malaria epitope induces a highly diverse cytotoxic T lymphocyte response. J. Immunol., 148, 1871–1878.
    • (1992) J. Immunol. , vol.148 , pp. 1871-1878
    • Romero, P.1    Eberl, G.2    Casanova, J.L.3    Cordey, A.S.4    Widmann, C.5    Luescher, I.6
  • 171
    • 0028231302 scopus 로고
    • Facile synthesis of homogeneous artificial proteins
    • Rose, K (1994). Facile synthesis of homogeneous artificial proteins. J. Am. Chem. Soc., 116, 30–33.
    • (1994) J. Am. Chem. Soc. , vol.116 , pp. 30-33
    • Rose, K.1
  • 172
    • 0024367007 scopus 로고
    • Circumsporozoite protein heterogeneity in the human malaria parasite plasmodium vivax
    • Rosenberg, R, Wirtz, R.A., Lanar, D.E., Sattabongkot, J., Hall, T., Waters, AP. et al. (1989). Circumsporozoite protein heterogeneity in the human malaria parasite Plasmodium vivax. Science, 245, 973–976.
    • (1989) Science , vol.245 , pp. 973-976
    • Rosenberg, R.1    Wirtz, R.A.2    Lanar, D.E.3    Sattabongkot, J.4    Hall, T.5    Waters, A.P.6
  • 174
    • 0026565205 scopus 로고
    • Protective immunization with invariant peptides of the plasmodium falciparum antigen msa2
    • Saul, A, Lord, R, Jones, G.L., and Spencer, L. (1992). Protective immunization with invariant peptides of the Plasmodium falciparum antigen MSA2. J. Immunol., 148, 208–211.
    • (1992) J. Immunol. , vol.148 , pp. 208-211
    • Saul, A.1    Lord, R.2    Jones, G.L.3    Spencer, L.4
  • 175
    • 0029966723 scopus 로고    scopus 로고
    • Influence of strong CD4+ T cell epitope on long-term virus-specific cytotoxic T cell responses induced in vivo with peptides
    • Sauzet, J.P., Gras-Masse, H., Guillet, J.G. and Gomard, E. (1996). Influence of strong CD4+ T cell epitope on long-term virus-specific cytotoxic T cell responses induced in vivo with peptides. Int. Immunol., 8, 457–465.
    • (1996) Int. Immunol. , vol.8 , pp. 457-465
    • Sauzet, J.P.1    Gras-Masse, H.2    Guillet, J.G.3    Gomard, E.4
  • 176
    • 0027217788 scopus 로고
    • Analysis ofthe human antibody response to Thrombospondin-Related Anonymous Protein of Plasmodium falciparum
    • Scarselli, E., Tolle, R, Koita, O., Diallo, M., Muller, H.M. Fruh, K et al. (1993). Analysis ofthe human antibody response to Thrombospondin-Related Anonymous Protein of Plasmodium falciparum. Infect. Immun., 61, 3490–3495.
    • (1993) Infect. Immun. , vol.61 , pp. 3490-3495
    • Scarselli, E.1    Tolle, R.2    Koita, O.3    Diallo, M.4    Muller, H.M.5    Fruh, K.6
  • 177
    • 0028097030 scopus 로고
    • Susceptibility of different strains of mice to hepatic infection with plasmodium berghei
    • Scheller, L.F., Wirtz, RA and Azad, AF. (1994). Susceptibility of different strains of mice to hepatic infection with Plasmodium berghei. Infect. Immun., 62, 4844–4847.
    • (1994) Infect. Immun. , vol.62 , pp. 4844-4847
    • Scheller, L.F.1    Wirtz, R.A.2    Azad, A.F.3
  • 178
    • 0029031772 scopus 로고
    • Maintenance of protective immunity against malaria by persistent hepatic parasites derived from irradiated sporozoites
    • Scheller, L.F. and Azad, A.F. (1995). Maintenance of protective immunity against malaria by persistent hepatic parasites derived from irradiated sporozoites. PNAS, 92, 4066–4068.
    • (1995) PNAS , vol.92 , pp. 4066-4068
    • Scheller, L.F.1    Azad, A.F.2
  • 179
    • 0026091287 scopus 로고
    • Efficiency of peptides and lipopeptides for in vivo priming of virus specific cytotoxic T cells
    • Schild, H., Deres, K, Wiesmuller, K.-H., Jung, G. Rammensee, H.-G. (1991). Efficiency of peptides and lipopeptides for in vivo priming of virus specific cytotoxic T cells. Eur. J. Immunol., 21, 2649–2654.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 2649-2654
    • Schild, H.1    Deres, K.2    Wiesmuller, K.-H.3    Jung, G.4    Rammensee, H.-G.5
  • 181
    • 0023199838 scopus 로고
    • Interferon-gamma inhibits the intrahepatocytic development of malaria parasites in vitro
    • Schofield, L., Ferreira, A., Altszuler, R, Nussenzweig, R and Nussenzweig, V. (1987). Interferon-gamma inhibits the intrahepatocytic development of malaria parasites in vitro. J. Immunol., 139, 2020–2025.
    • (1987) J. Immunol. , vol.139 , pp. 2020-2025
    • Schofield, L.1    Ferreira, A.2    Altszuler, R.3    Nussenzweig, R.4    Nussenzweig, V.5
  • 182
    • 0026034957 scopus 로고
    • Peptide-induced antiviral protection by cytotoxic T cells
    • Schulz, M., Zinkernagel, R.M. and Hengartner H. (1991). Peptide-induced antiviral protection by cytotoxic T cells. PNAS, 88, 991–993.
    • (1991) PNAS , vol.88 , pp. 991-993
    • Schulz, M.1    Zinkernagel, R.M.2    Hengartner, H.3
  • 183
    • 0022358985 scopus 로고
    • Carrier-induced epitopic suppression, a major issue for future synthetic vaccines
    • Schutze, M.-P., Leclerc, C., Jolivet, M., Audibert, F. and Chedid, L. (1985). Carrier-induced epitopic suppression, a major issue for future synthetic vaccines. J. Immunol., 135, 2319–2322.
    • (1985) J. Immunol. , vol.135 , pp. 2319-2322
    • Schutze, M.-P.1    Leclerc, C.2    Jolivet, M.3    Audibert, F.4    Chedid, L.5
  • 184
    • 0026649726 scopus 로고
    • Naturally acquired cytotoxic T lymphocytes against the plasmodium falciparum circumsporozoite protein
    • Sedegah, M., Sim, K.L., Mason, C., Nutman, T., Malik, A., Roberts, C. et al. (1992). Naturally acquired cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein. J. Immunol., 149, 966–971.
    • (1992) J. Immunol. , vol.149 , pp. 966-971
    • Sedegah, M.1    Sim, K.L.2    Mason, C.3    Nutman, T.4    Malik, A.5    Roberts, C.6
  • 185
    • 0028077102 scopus 로고
    • Protection against malaria by immunization with plasmid dna encoding circumsporozoite protein
    • Sedegah, M., Hedstrom, R, Hobart, P. and Hoffman, S.L. (1994). Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein. PNAS, 91, 9866–9870.
    • (1994) PNAS , vol.91 , pp. 9866-9870
    • Sedegah, M.1    Hedstrom, R.2    Hobart, P.3    Hoffman, S.L.4
  • 186
    • 0024431497 scopus 로고
    • Interactions of plasmodium berghei sporozoites and murine kupffer cells in vitro
    • Seguin, M.C., Ballou, W.R and Nacy, C.A. 1989. Interactions of Plasmodium berghei sporozoites and murine Kupffer cells in vitro. J. Immunol., 143, 1716–1722.
    • (1989) J. Immunol. , vol.143 , pp. 1716-1722
    • Seguin, M.C.1    Ballou, W.R.2    Nacy, C.A.3
  • 187
    • 0028355754 scopus 로고
    • Induction of nitric oxide synthase protects against malaria in mice exposed to irradiated plasmodium berghei infected mosquitoes: Involvement of interferon gamma and CD8+ T cells
    • Seguin, M., Klotz, F., Schneider, I., Weir, J.P., Goodbary, M., Slayter, M. et al. (1994). Induction of nitric oxide synthase protects against malaria in mice exposed to irradiated Plasmodium berghei infected mosquitoes: Involvement of interferon gamma and CD8+ T cells. J. Exp. Med., 180, 353–358.
    • (1994) J. Exp. Med. , vol.180 , pp. 353-358
    • Seguin, M.1    Klotz, F.2    Schneider, I.3    Weir, J.P.4    Goodbary, M.5    Slayter, M.6
  • 188
    • 0027973079 scopus 로고
    • The relationship between class I binding affinity and immunogenicity of cytotoxic T cell epitopes
    • Sette, A., Vitiello, A., Reherman, B., Fowler, P., Nayersina, R., Kast, W.M. et al. (1994). The relationship between class I binding affinity and immunogenicity of cytotoxic T cell epitopes. J. Immunol., 153, 5586–5592.
    • (1994) J. Immunol. , vol.153 , pp. 5586-5592
    • Sette, A.1    Vitiello, A.2    Reherman, B.3    Fowler, P.4    Nayersina, R.5    Kast, W.M.6
  • 189
    • 0029933925 scopus 로고    scopus 로고
    • Antibodies to a conserved-motif peptide sequence of the plasmodium falciparum thrombospondin related anonymous protein and circumsporozoite protein recognize a 78 kilodalton protein I the asexual blood stages of the parasite and inhibit merozoite invasion in vitro
    • Shanna, P., Bharadwaj, A., Bhasin, V.K., Sailaja, V.N. and Chauhan, V.S. (1996). Antibodies to a conserved-motif peptide sequence of the Plasmodium falciparum thrombospondin related anonymous protein and circumsporozoite protein recognize a 78 kilodalton protein I the asexual blood stages of the parasite and inhibit merozoite invasion in vitro. Infect. Immun., 64, 2172–2179.
    • (1996) Infect. Immun. , vol.64 , pp. 2172-2179
    • Shanna, P.1    Bharadwaj, A.2    Bhasin, V.K.3    Sailaja, V.N.4    Chauhan, V.S.5
  • 190
    • 0027451764 scopus 로고
    • Co-dominant and reciprocal T helper cell activity ofepitopic sequences and fonnation of junctional b cell determinants in synthetic t:B chim eric immunogens
    • Sharrna, P., Kumar, A., Batni, S. and Chauhan, V.S. 1993. Co-dominant and reciprocal T helper cell activity ofepitopic sequences and fonnation of junctional B cell determinants in synthetic T:B chim eric immunogens. Vaccine, 11, 1321–1326.
    • (1993) Vaccine , vol.11 , pp. 1321-1326
    • Sharrna, P.1    Kumar, A.2    Batni, S.3    Chauhan, V.S.4
  • 191
    • 0020380401 scopus 로고
    • Direct infection of hepatocytes by sporozoites of plasmodium berghei
    • Shin, S.C.J., Vanderberg, J.P. and Terzakis, J.A. (1982). Direct infection of hepatocytes by sporozoites of Plasmodium berghei. J. Protozool., 29, 448–454.
    • (1982) J. Protozool. , vol.29 , pp. 448-454
    • Shin, S.C.J.1    Vanderberg, J.P.2    Terzakis, J.A.3
  • 192
    • 0029897044 scopus 로고    scopus 로고
    • Practical, biochemical and evolutionary implications of the discovery of hla class I supernotifs
    • Sidney, J., Grey, H.M., Kubo, R.T and Sette, A (1996). Practical, biochemical and evolutionary implications of the discovery of HLA class I supernotifs. Immunol. Today 17, 261–266.
    • (1996) Immunol. Today , vol.17 , pp. 261-266
    • Sidney, J.1    Grey, H.M.2    Kubo, R.T.3    Sette, A.4
  • 193
    • 0024204050 scopus 로고
    • A malaria T-cell epitope recognized in association with most mouse and human MHC class ii molecules
    • Sinigaglia, E, Guttinger, M., Kilgus, J., Doran, D.M., Matile, H., Etlinger, H. et al. (1988). A malaria T-cell epitope recognized in association with most mouse and human MHC class II molecules. Nature, 336, 778780.
    • (1988) Nature , vol.336 , pp. 778-780
    • Sinigaglia, E.1    Guttinger, M.2    Kilgus, J.3    Doran, D.M.4    Matile, H.5    Etlinger, H.6
  • 194
    • 0028966203 scopus 로고
    • Motifs and supennotifs for MHC class ii binding peptides
    • Sinigaglia, G. and Hammer, J. (1995). Motifs and supennotifs for MHC class II binding peptides. J. Exp. Med., 181, 449–451.
    • (1995) J. Exp. Med. , vol.181 , pp. 449-451
    • Sinigaglia, G.1    Hammer, J.2
  • 195
    • 0028303174 scopus 로고
    • Structural and functional properties of region ii plus of the malaria circumsporozoite protein
    • Sinnis, P., Clavijo, P., Fenyo, D., Chait, B.T., Cerami, C. and Nussenzweig, V. (1994). Structural and functional properties of region II plus of the malaria circumsporozoite protein. J. Exp. Med., 180, 297–306.
    • (1994) J. Exp. Med. , vol.180 , pp. 297-306
    • Sinnis, P.1    Clavijo, P.2    Fenyo, D.3    Chait, B.T.4    Cerami, C.5    Nussenzweig, V.6
  • 196
    • 0001169418 scopus 로고
    • Effect of various routes of immunization and methods of parasite attenuation on the development of protection against sporozoite-induced rodent mal aria
    • Spitalny, G.L and Nussenzweig, R.S. (1972). Effect of various routes of immunization and methods of parasite attenuation on the development of protection against sporozoite-induced rodent mal aria. Proc. Helminthol. Soc., 39. 506–514.
    • (1972) Proc. Helminthol. Soc. , vol.39 , pp. 506-514
    • Spitalny, G.L.1    Nussenzweig, R.S.2
  • 197
    • 0026952159 scopus 로고
    • Electron microscopic analysis of circumsporozoite protein trail formation by gliding malaria sporozoites
    • Stewart, MJ. and Vanderberg, J.P. (1992). Electron microscopic analysis of circumsporozoite protein trail formation by gliding malaria sporozoites. J. Protozool., 39, 663–671.
    • (1992) J. Protozool. , vol.39 , pp. 663-671
    • Stewart, M.J.1    Vanderberg, J.P.2
  • 198
    • 0022608130 scopus 로고
    • Plasmodium berghei sporozoite invasion is blocked in vitro by sporozoite immobilizing antibodies
    • Stewart, M., Nawrot, R., Schulman, S., Vanderberg, J.P. (1986). Plasmodium berghei sporozoite invasion is blocked in vitro by sporozoite immobilizing antibodies. Infect. Immun., 51, 859–864.
    • (1986) Infect. Immun. , vol.51 , pp. 859-864
    • Stewart, M.1    Nawrot, R.2    Schulman, S.3    Vanderberg, J.P.4
  • 199
    • 0004170486 scopus 로고    scopus 로고
    • A preliminary evaluation of a recombinant circumsporozoite protein vaccine against plasmodium falciparum malaria
    • RTS, S Malaria Vaccine Evaluation Group
    • Stoute, J.A., Siaoui, M., Heppner, D.G., Momin, P., Keser, K.E., Desmons, P. et al. (1997). A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS, S Malaria Vaccine Evaluation Group. New Eng. J. Med., 336, 86–91.
    • (1997) New Eng. J. Med. , vol.336 , pp. 86-91
    • Stoute, J.A.1    Siaoui, M.2    Heppner, D.G.3    Momin, P.4    Keser, K.E.5    Desmons, P.6
  • 200
    • 0030745648 scopus 로고    scopus 로고
    • Trap is necessary for gliding motility and infectivity of plasmodium sporozoites
    • Sultan, A, Thathy, V, Frevert, U., Robson, K.J.H., Crisanti, A., Nussenzweig, V. et al. (1997). TRAP is necessary for gliding motility and infectivity of Plasmodium sporozoites. Cell, 90, 1–12.
    • (1997) Cell , vol.90 , pp. 1-12
    • Sultan, A.1    Thathy, V.2    Frevert, U.3    Robson, K.J.H.4    Crisanti, A.5    Nussenzweig, V.6
  • 201
    • 0030297819 scopus 로고    scopus 로고
    • Plasmodium yoelii: Peptide immunization induces protective CD4+ T cells against a previously unrecognized cryptic epitope of the circumsporozoite protein
    • Takita-Sonoda, Y, Tsuji, M., Kamboj, K., Nussenzweig, R.S., Calvijo, P. and Zavala, E (1996). Plasmodium yoelii: Peptide immunization induces protective CD4+ T cells against a previously unrecognized cryptic epitope of the circumsporozoite protein. Exp. Parasitol., 84, 223–230.
    • (1996) Exp. Parasitol. , vol.84 , pp. 223-230
    • Takita-Sonoda, Y.1    Tsuji, M.2    Kamboj, K.3    Nussenzweig, R.S.4    Calvijo, P.5    Zavala, E.6
  • 202
    • 0001331728 scopus 로고
    • Synthetic peptide vaccine design: Synthesis and properties of a high-density multiple antigenic peptide system
    • Tam, J.P. (1988). Synthetic peptide vaccine design: Synthesis and properties of a high-density multiple antigenic peptide system. PNAS, 85, 5409–5413.
    • (1988) PNAS , vol.85 , pp. 5409-5413
    • Tam, J.P.1
  • 203
    • 0024310231 scopus 로고
    • Vaccine engineering: Enhancement of immunogenicity of synthetic peptide vaccines related to hepatitis in chemically defined models consisting of T- and B-cell epitopes
    • Tam, J.P. and Lu, Y.-A. (1989). Vaccine engineering: enhancement of immunogenicity of synthetic peptide vaccines related to hepatitis in chemically defined models consisting of T- and B-cell epitopes. PNAS, 86, 9084–9088.
    • (1989) PNAS , vol.86 , pp. 9084-9088
    • Tam, J.P.1    Lu, Y.-A.2
  • 204
    • 0025099759 scopus 로고
    • Incorporation of T and b epitopes of the circumsporozoite protein in a chemically defined synthetic vaccine against malaria
    • Tam, J.P., Clavijo, P., Lu, YA, Nussenzweig, V., Nussenzweig, R. and Zavala, F. (1990). Incorporation of T and B epitopes of the circumsporozoite protein in a chemically defined synthetic vaccine against malaria. J. Exp. Med., 171, 299–306.
    • (1990) J. Exp. Med. , vol.171 , pp. 299-306
    • Tam, J.P.1    Clavijo, P.2    Lu, Y.A.3    Nussenzweig, V.4    Nussenzweig, R.5    Zavala, F.6
  • 205
    • 0029833251 scopus 로고    scopus 로고
    • Recent advances in multiple antigen peptides
    • Tam, J.P. (1996). Recent advances in multiple antigen peptides. J. Immunol. Meth., 196, 17–32.
    • (1996) J. Immunol. Meth. , vol.196 , pp. 17-32
    • Tam, J.P.1
  • 207
    • 0031229803 scopus 로고    scopus 로고
    • Chimeric peptides: A new approach to enhancing the immunogenicity of peptides with low MHC class I affinity
    • Application in antiviral vaccination
    • Tourdot, S., Oukka, M., Manuguerra, J.C., Magafa, V, Vergnon, 1., Riche, N. et al. (1997), Chimeric Peptides: A new approach to enhancing the immunogenicity of peptides with low MHC class I affinity. Application in antiviral vaccination. J. Immunol., 159, 2391–2398.
    • (1997) J. Immunol. , vol.159 , pp. 2391-2398
    • Tourdot, S.1    Oukka, M.2    Manuguerra, J.C.3    Magafa, V.4
  • 208
    • 0029617767 scopus 로고
    • Molecular cloning of a gene from plasmodium falciparum that codes for a protein sharing motifs found in adhesive molecules from mammals and plasmodia
    • Trottein, E, Triglia, T. and Cowman, A.E (1995). Molecular cloning of a gene from Plasmodium falciparum that codes for a protein sharing motifs found in adhesive molecules from mammals and plasmodia. Mol. Biochem. Parasitol., 74, 129–141.
    • (1995) Mol. Biochem. Parasitol. , vol.74 , pp. 129-141
    • Trottein, E.1    Triglia, T.2    Cowman, A.E.3
  • 209
    • 0025038617 scopus 로고
    • Cd4+ cytolytic T cell clone confers protection against murine malaria
    • Tsuji, M., Romero, P, Nussenzweig, R. and Zavala, E (1990). CD4+ cytolytic T cell clone confers protection against murine malaria. J. Exp. Med., 172, 1353–1357.
    • (1990) J. Exp. Med. , vol.172 , pp. 1353-1357
    • Tsuji, M.1    Romero, P.2    Nussenzweig, R.3    Zavala, E.4
  • 210
  • 211
    • 0026703523 scopus 로고
    • Use of human universally antigenic tetanus toxin T cell epitopes as carriers for human vaccination
    • Valmori, D., Pessi, A., Bianchi, E. and Corradin, G. (1992). Use of human universally antigenic tetanus toxin T cell epitopes as carriers for human vaccination. J. Immunol., 149, 717–721.
    • (1992) J. Immunol. , vol.149 , pp. 717-721
    • Valmori, D.1    Pessi, A.2    Bianchi, E.3    Corradin, G.4
  • 212
    • 0028306427 scopus 로고
    • Induction of a cytotoxic T cell response by co-injection of a th peptide and a CTL peptide in ifa: Further enhancement by preinjection of ifa alone
    • Valmori, D., Romero, J., Men, Y., Mayanski, J., Romero, P. and Corradin G. (1994). Induction of a cytotoxic T cell response by co-injection of a Th peptide and a CTL peptide in IFA: further enhancement by preinjection of IFA alone. Eur. J. Immunol., 24, 1458–1462.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1458-1462
    • Valmori, D.1    Romero, J.2    Men, Y.3    Mayanski, J.4    Romero, P.5    Corradin, G.6
  • 213
    • 0014398017 scopus 로고
    • Protective immunity produced by the injection of X-irradiated sporozoites of plasmodium berghei. Ii effects of radiation on sporozoites
    • Vanderberg, J.P., Nussenzweig, R.S., Most, H. and Orton, C.G. (1968). Protective immunity produced by the injection of X-irradiated sporozoites of Plasmodium berghei. II Effects of radiation on sporozoites. J. Parasitol., 54, 1175–1180.
    • (1968) J. Parasitol. , vol.54 , pp. 1175-1180
    • Vanderberg, J.P.1    Nussenzweig, R.S.2    Most, H.3    Orton, C.G.4
  • 214
    • 0014576951 scopus 로고
    • Protective immunity produced by injections of X-irradiated sporozoites of plasmodium berghei. V. In vitro effects of immune serum on sporozoites
    • Vanderberg, J.P., Nussenzweig, R. and Most, H. (1969). Protective immunity produced by injections of X-irradiated sporozoites of Plasmodium berghei. V. In vitro effects of immune serum on sporozoites. Milit. Med., 134, Suppl., 1183–1190.
    • (1969) Milit. Med. , vol.134 , pp. 1183-1190
    • Vanderberg, J.P.1    Nussenzweig, R.2    Most, H.3
  • 215
    • 0007874805 scopus 로고
    • Protective immunity produced by the bite of X-irradiated mosquitoes infected with plasmodium berghei
    • Vanderberg, J.P., Nussenzweig, R.S. and Most, H. (1970). Protective immunity produced by the bite of X-irradiated mosquitoes infected with Plasmodium berghei. J. Parasitol., 56, 350–351.
    • (1970) J. Parasitol. , vol.56 , pp. 350-351
    • Vanderberg, J.P.1    Nussenzweig, R.S.2    Most, H.3
  • 216
    • 0025602648 scopus 로고
    • Plasmodium sporozoite interactions with macrophages in vitro: A videomicroscopic analysis
    • Vanderberg, J., Chew, S. and Stewart, MJ. (1990). Plasmodium sporozoite interactions with macrophages in vitro: a videomicroscopic analysis. J. Protozool., 37, 28–36.
    • (1990) J. Protozool. , vol.37 , pp. 28-36
    • Vanderberg, J.1    Chew, S.2    Stewart, M.J.3
  • 217
    • 0029974607 scopus 로고    scopus 로고
    • Immunogenicity of peptides bound to MHC class I molecules depends on the MHC peptide complex stability
    • van der Burg, S.H., Visseren, M.J.W., Brandt, R.M.P., Kast, W.M. and Melief, C.J.M. (1996). Immunogenicity of peptides bound to MHC class I molecules depends on the MHC peptide complex stability. J. Immunol., 156, 3308–3314.
    • (1996) J. Immunol. , vol.156 , pp. 3308-3314
    • Van Der Burg, S.H.1    Visseren, M.J.W.2    Brandt, R.M.P.3    Kast, W.M.4    Melief, C.J.M.5
  • 218
    • 0029810418 scopus 로고    scopus 로고
    • Peptide pulsed dendritic cells induce tumoricidal cytotoxic T lymphocytes from healthy donors against stably hla-a*0201 binding peptides from the melan-a/mart-1 self antigen
    • Van Elas, A., van der Burg, A.H., van der Minne, C.E., Borghi, M., Mourer, J.S., Melief, CJM. et al. (1996). Peptide pulsed dendritic cells induce tumoricidal cytotoxic T lymphocytes from healthy donors against stably HLA-A*0201 binding peptides from the Melan-A/MART-1 self antigen. Eur. J. Immunol., 26, 1683–1689.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1683-1689
    • Van Elas, A.1    Van Der Burg, A.H.2    Van Der Minne, C.E.3    Borghi, M.4    Mourer, J.S.5    Melief, C.J.M.6
  • 219
    • 0029033477 scopus 로고
    • Manopalmitic acid-peptide conjugates induce cytotoxic T cell responses against malarial epitopes: Importance of spacer amino acids
    • Verheul, A.F, Udhayakumar, V, Jue, D.L., Wohlhueter, R.M. and Lal, A.A. (1995). Manopalmitic acid-peptide conjugates induce cytotoxic T cell responses against malarial epitopes: importance of spacer amino acids. J. Immunol. Meth., 182, 219–226.
    • (1995) J. Immunol. Meth. , vol.182 , pp. 219-226
    • Verheul, A.F.1    Udhayakumar, V.2    Jue, D.L.3    Wohlhueter, R.M.4    Lal, A.A.5
  • 220
    • 0028876917 scopus 로고
    • Development of a lipopeptide-based therapeutic vaccine to treat chronic hbv infection i. Induction of a primary cytotoxic T lymphocyte response in humans
    • Vitiello, A., Ishioka, G., Grey, H.M., Rose, R., Farness, P., LaFond, R. et al. (1995). Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection I. Induction of a primary cytotoxic T lymphocyte response in humans. J. Clin. Invest., 95, 341–349.
    • (1995) J. Clin. Invest. , vol.95 , pp. 341-349
    • Vitiello, A.1    Ishioka, G.2    Grey, H.M.3    Rose, R.4    Farness, P.5    LaFond, R.6
  • 221
    • 0026732781 scopus 로고
    • Cationic lipids direct a viral glycoprotein into the class I major histocompatibility complex antigen-presentation pathway
    • Walker, C., Selby, M., Erickson, A., Cataldo, D., Valensi, J.P. and Van Nest, G. (1992). Cationic lipids direct a viral glycoprotein into the class I major histocompatibility complex antigen-presentation pathway. PNAS, 89, 7915–7918.
    • (1992) PNAS , vol.89 , pp. 7915-7918
    • Walker, C.1    Selby, M.2    Erickson, A.3    Cataldo, D.4    Valensi, J.P.5    Van Nest, G.6
  • 222
    • 0028952801 scopus 로고
    • Induction ofprotective polyclonal antibodies by immunization with a plasmodium yoelii circumsporozoite protein multiple antigen peptide vaccine
    • Wang, R., Charoenvit, Y., Corradin, G., Porrozzi, R., Hunter, R.L., Glenn, G. etal. (1995). Induction ofprotective polyclonal antibodies by immunization with a Plasmodium yoelii circumsporozoite protein multiple antigen peptide vaccine. J. Immunol., 154, 2784–2793.
    • (1995) J. Immunol. , vol.154 , pp. 2784-2793
    • Wang, R.1    Charoenvit, Y.2    Corradin, G.3    Porrozzi, R.4    Hunter, R.L.5    Glenn, G.6
  • 223
    • 0030293622 scopus 로고    scopus 로고
    • Protection against malaria by plasmodium yoelii sporozoite surface protein 2 linear peptide induction of CD4+ T cell- and ifn-y dependent elimination of infected hepatocytes
    • Wang, R., Charoenvit, Y., Corradin, G., De la Vega, P., Franke, E.D. and Hoffman, S.L. (1996a). Protection against malaria by Plasmodium yoelii sporozoite surface protein 2 linear peptide induction of CD4+ T cell- and IFN-y dependent elimination of infected hepatocytes. J. Immunol., 157, 4061–4067.
    • (1996) J. Immunol. , vol.157 , pp. 4061-4067
    • Wang, R.1    Charoenvit, Y.2    Corradin, G.3    De La Vega, P.4    Franke, E.D.5    Hoffman, S.L.6
  • 224
    • 0030294673 scopus 로고    scopus 로고
    • Protective efficacy against malaria of a combination sporozoite and erythrocytic stage vaccine
    • Wang, R., Charoenvit, Y., Daly, T.M., Long, C.A., Corradin, G. and Holman, S.L. (1996b). Protective efficacy against malaria of a combination sporozoite and erythrocytic stage vaccine. Immunol. Lett., 53, 83–93.
    • (1996) Immunol. Lett. , vol.53 , pp. 83-93
    • Wang, R.1    Charoenvit, Y.2    Daly, T.M.3    Long, C.A.4    Corradin, G.5    Holman, S.L.6
  • 225
    • 0023121572 scopus 로고
    • A synthetic peptide induces long-term protection from lethal infection with herpes simplex virus 2
    • Watari, E., Dietzschold, B., Szokan, G. and Heber-Katz, E. (1987). A synthetic peptide induces long-term protection from lethal infection with herpes simplex virus 2. J. Exp. Med., 165, 459–470.
    • (1987) J. Exp. Med. , vol.165 , pp. 459-470
    • Watari, E.1    Dietzschold, B.2    Szokan, G.3    Heber-Katz, E.4
  • 226
    • 0021812461 scopus 로고
    • Structure of the circumsporozoite protein gene in 18 strains of plasmodium falciparum
    • Weber, J.L. and Hockmeyer, W.T. (1985). Structure of the circumsporozoite protein gene in 18 strains of Plasmodium falciparum. Mol. Biochem. Parasitol., 15, 305–310.
    • (1985) Mol. Biochem. Parasitol. , vol.15 , pp. 305-310
    • Weber, J.L.1    Hockmeyer, W.T.2
  • 228
    • 0001435165 scopus 로고
    • Cd8+ T cells (Cytotoxic/suppressors) are required for protection in mice immunized with malaria sporozoites
    • Weiss, W.R., Sedegah, M., Beaudoin, R.L., Miller, L.H. and Good, M. (1988). CD8+ T cells (cytotoxic/suppressors) are required for protection in mice immunized with malaria sporozoites. PNAS, 85, 573–576.
    • (1988) PNAS , vol.85 , pp. 573-576
    • Weiss, W.R.1    Sedegah, M.2    Beaudoin, R.L.3    Miller, L.H.4    Good, M.5
  • 229
    • 0024822420 scopus 로고
    • Genetic control of immunity to plasmodium yoelii sporozoites
    • Weiss, w., Good, M., Hollingdale, M., Miller, L. and Berzofsky, J. (1989). Genetic control of immunity to Plasmodium yoelii sporozoites. J. Immunol., 143, 4263–4266.
    • (1989) J. Immunol. , vol.143 , pp. 4263-4266
    • Weiss, W.1    Good, M.2    Hollingdale, M.3    Miller, L.4    Berzofsky, J.5
  • 230
    • 0025275579 scopus 로고
    • Cytotoxic T cells recognize a peptide from the circumsporozoite protein on malaria-infected hepatocytes
    • Weiss, W.R., Mellouk, S., Houghten, R.A., Sedegah, M., Kumar, S., Good, M.F et al. (1990). Cytotoxic T cells recognize a peptide from the circumsporozoite protein on malaria-infected hepatocytes. J. Exp. Med., 171, 763–773.
    • (1990) J. Exp. Med. , vol.171 , pp. 763-773
    • Weiss, W.R.1    Mellouk, S.2    Houghten, R.A.3    Sedegah, M.4    Kumar, S.5    Good, M.F.6
  • 231
    • 0029883981 scopus 로고    scopus 로고
    • Mhc class i-dependent presentation of exoerythrocytic antigens to CD8+ T lymphocytes is required for protective immunity against plasmodium berghei
    • White, K.L., Snyder, H.L. and Krzych, U. (1996). MHC class I-dependent presentation of exoerythrocytic antigens to CD8+ T lymphocytes is required for protective immunity against Plasmodium berghei. J. Immunol., 156, 3374–3381.
    • (1996) J. Immunol. , vol.156 , pp. 3374-3381
    • White, K.L.1    Snyder, H.L.2    Krzych, U.3
  • 232
    • 0025889027 scopus 로고
    • Differential stability of antigenic MHC class I restricted synthetic peptides
    • Widman, C., Maryanski, J.L., Romero, P. and Corradin, G. (1991). Differential stability of antigenic MHC class I restricted synthetic peptides. J. Immunol., 147, 3745–3750.
    • (1991) J. Immunol. , vol.147 , pp. 3745-3750
    • Widman, C.1    Maryanski, J.L.2    Romero, P.3    Corradin, G.4
  • 233
    • 0026739624 scopus 로고
    • T helper epitopes enhance the cytotoxic response of mice immunized with MHC class i-restricted malaria peptides
    • Widman, C, Romero, R, Maryanski, J. Corradin, G, and Valmori, D, (1992). T helper epitopes enhance the cytotoxic response of mice immunized with MHC class I-restricted malaria peptides. J. Immunol. Meth., 155, 95–99.
    • (1992) J. Immunol. Meth. , vol.155 , pp. 95-99
    • Widman, C.1    Romero, R.2    Maryanski, J.3    Corradin, G.4    Valmori, D.5
  • 234
    • 0026030524 scopus 로고
    • The antibody response in balb/c mice to the plasmodium falciparum circumsporozoite repetitive epitope covalently coupled to synthetic lipopeptide adjuvant
    • Wiesmuller, K-H., Jung, G., Gillessen, D., Loffl, C, Bessler, W.G. and Boltz, T. (1991). The antibody response in BALB/C mice to the Plasmodium falciparum circumsporozoite repetitive epitope covalently coupled to synthetic lipopeptide adjuvant. Immunology, 72, 109–113.
    • (1991) Immunology , vol.72 , pp. 109-113
    • Wiesmuller, K.-H.1    Jung, G.2    Gillessen, D.3    Loffl, C.4    Bessler, W.G.5    Boltz, T.6
  • 235
    • 0028261019 scopus 로고
    • Induction of murine cytotoxic T lymphocytes against plasmodiumfalciparum sporozoite surface protein 2
    • Wizel, B., Rogers, W.O., Houghten, R., Lanar, D., Tine, J. and Hoffman, S. (1994). Induction of murine cytotoxic T lymphocytes against Plasmodiumfalciparum sporozoite surface protein 2. Eur. J. Immunol., 24, 1487–1495.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1487-1495
    • Wizel, B.1    Rogers, W.O.2    Houghten, R.3    Lanar, D.4    Tine, J.5    Hoffman, S.6
  • 236
    • 0029017114 scopus 로고
    • HLA-A2.1 restricted cytotoxic T lymphocyte responses to multiple plasmodiumfalciparum sporozoite surface protein 2 epitopes in sporozoite immunized volunteers
    • Wizel, B., Houghten, R., Church, P., Tine, J.A, Lanar, D.E., Gordon, D.M. et al. (1995a). HLA-A2.1 restricted cytotoxic T lymphocyte responses to multiple Plasmodiumfalciparum sporozoite surface protein 2 epitopes in sporozoite immunized volunteers. Immunol., 155, 766–775.
    • (1995) Immunol , vol.155 , pp. 766-775
    • Wizel, B.1    Houghten, R.2    Church, P.3    Tine, J.A.4    Lanar, D.E.5    Gordon, D.M.6
  • 237
    • 0028821821 scopus 로고
    • Irradiated sporozoite vaccine induces HLA-B8 restricted cytotoxic T lymphocyte responses against two overlapping epitopes of plasmodium falciparum surface sporozoite protein 2
    • Wizel, B., Houghten, R.A., Parker, K., Coligan, J.E., Church, P, Gordon, D.M. et al. (1995b). Irradiated sporozoite vaccine induces HLA-B8 restricted cytotoxic T lymphocyte responses against two overlapping epitopes of Plasmodium falciparum surface sporozoite protein 2. J. Exp. Med., 182, 1435–1445.
    • (1995) J. Exp. Med. , vol.182 , pp. 1435-1445
    • Wizel, B.1    Houghten, R.A.2    Parker, K.3    Coligan, J.E.4    Church, P.5    Gordon, D.M.6
  • 238
    • 0025794225 scopus 로고
    • Antigenicity and immunogenicity of a multiple peptidic construction of the schistosoma mansoni Sm-28 GST antigen in rat, mouse, and monkey. J. Partial protection of fischer rats after active immunization
    • Wolowczuk, I., Auriault, C, Bossus, M., Boulanger, D., Gras-Masse, H., Mazingue, C. et al. (1991). Antigenicity and immunogenicity of a multiple peptidic construction of the Schistosoma mansoni Sm-28 GST antigen in rat, mouse, and monkey. J. Partial protection of Fischer rats after active immunization. J. Immunol., 146, 1987–1995.
    • (1991) J. Immunol. , vol.146 , pp. 1987-1995
    • Wolowczuk, I.1    Auriault, C.2    Bossus, M.3    Boulanger, D.4    Gras-Masse, H.5    Mazingue, C.6
  • 239
    • 0018891152 scopus 로고
    • Hybridoma produces protective antibodies directed against the sporozoite stage of malaria parasite
    • Yoshida, N., Nussenzweig, R.S., Potocnjak, P., Nussenzweig, V. and Aikawa, M. (1980). Hybridoma produces protective antibodies directed against the sporozoite stage of malaria parasite. Science, 207, 71–73.
    • (1980) Science , vol.207 , pp. 71-73
    • Yoshida, N.1    Nussenzweig, R.S.2    Potocnjak, P.3    Nussenzweig, V.4    Aikawa, M.5
  • 241
    • 0020620942 scopus 로고
    • Circumsporozoite proteins of malaria parasites contain a single immunodominant region with two or more identical epitopes
    • Zavala, E, Cochrane, AH., Nardin, E.H., Nussenzweig, R.S. and Nussenzweig, V. (1983). Circumsporozoite proteins of malaria parasites contain a single immunodominant region with two or more identical epitopes. J. Exp. Med., 157, 1947–1957.
    • (1983) J. Exp. Med. , vol.157 , pp. 1947-1957
    • Zavala, E.1    Cochrane, A.H.2    Nardin, E.H.3    Nussenzweig, R.S.4    Nussenzweig, V.5
  • 242
    • 0023622196 scopus 로고
    • Synthetic peptide vaccine confers protection against murine mal aria
    • Zavala, E Tam, J.P., Barr, P.J., Romero, P.J., Ley, V., Nussenzweig, R.S. et al. (1987). Synthetic peptide vaccine confers protection against murine mal aria. J. Exp. Med., 166, 1591–1596.
    • (1987) J. Exp. Med. , vol.166 , pp. 1591-1596
    • Zavala, E.1    Tam, J.P.2    Barr, P.J.3    Romero, P.J.4    Ley, V.5    Nussenzweig, R.S.6
  • 243
    • 0021800242 scopus 로고
    • Rationale for development of a synthetic vaccine against plasmodium falciparum malaria
    • Zavala, F., Tam, J.P., Hollingdale, M.R., Cochrane, AH., Quakyi, I., Nussenzweig, R.S. et al. (1985). Rationale for development of a synthetic vaccine against Plasmodium falciparum malaria. Science, 228, 1436–1440.
    • (1985) Science , vol.228 , pp. 1436-1440
    • Zavala, F.1    Tam, J.P.2    Hollingdale, M.R.3    Cochrane, A.H.4    Quakyi, I.5    Nussenzweig, R.S.6
  • 244
    • 0025078948 scopus 로고
    • Protective anti-sporozoite antibodies induced by a chemically defined synthetic vaccine
    • Zavala, F. and Chai, S. (1990). Protective anti-sporozoite antibodies induced by a chemically defined synthetic vaccine. Immunol. Lett., 25, 271–274.
    • (1990) Immunol. Lett. , vol.25 , pp. 271-274
    • Zavala, F.1    Chai, S.2


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