Induction of sustained and elevated immune responses to weakly immunogenic synthetic malarial peptides by encapsulation in biodegradable polymer microspheres

Vaccine

Volumn 14, Issue 15, 1996, Pages 1442-1450

  Men, Ying ^a   Gander, Bruno ^b   Merkle, Hans P ^b   Corradin, Giampietro ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b ETH ZURICH   (Switzerland)

Author keywords

Adjuvant; Biodegradable polymer microspheres; Synthetic peptide; T cell and antibody responses; Vaccine

Indexed keywords

EPITOPE; MALARIA VACCINE; MICROSPHERE; POLYMER; SYNTHETIC PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; BIODEGRADATION; CONTROLLED STUDY; ENCAPSULATION; MALARIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; VACCINATION;

AMINO ACID SEQUENCE; ANIMALS; BIOCOMPATIBLE MATERIALS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EPITOPES; FEMALE; IMMUNOGLOBULINS; LACTIC ACID; LYMPH NODES; MALARIA VACCINES; MICE; MICE, INBRED BALB C; MICROSPHERES; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; POLYESTERS; POLYGLYCOLIC ACID; POLYMERS; T-LYMPHOCYTES; TETANUS TOXIN; TETANUS TOXOID; TIME FACTORS; VACCINES, SYNTHETIC;

EID: 0030459553     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(96)00074-6     Document Type: Article

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