Influence of strong CD4 epitope on long-term virus-specific cytotoxic T cell responses induced in vivo with peptides

International Immunology

Volumn 8, Issue 4, 1996, Pages 457-465

  Sauzet, Jean Pierre ^b   Gras Masse, Helene ^a   Guillet, Jean Gerard ^b   Gomard, Elisabeth ^b  

^a UNIV LILLE   (France)

^b INSTITUT COCHIN   (France)

Author keywords

Cytotoxic T lymphocytes; Long lasting responses; Peptide

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; EPITOPE; PEPTIDE; VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; HELPER CELL; IMMUNIZATION; INFLUENZA VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; VACCINE PRODUCTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, CD4; ANTIGENS, CD8; CD4-POSITIVE T-LYMPHOCYTES; CYTOTOXICITY, IMMUNOLOGIC; EPITOPES, T-LYMPHOCYTE; HISTOCOMPATIBILITY ANTIGENS CLASS II; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED CBA; MOLECULAR SEQUENCE DATA; ORTHOMYXOVIRIDAE; T-LYMPHOCYTES, CYTOTOXIC; VACCINATION;

EID: 0029966723     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/8.4.457     Document Type: Article

References (47)

1. + cytotoxic T-cell responses? A paradox revisited. Immunol Today 14.344
2. + cells in the generation of killer activity. J Exp Med 141:1390.
3. + T cells to proliferation and cytotoxic activity. J. Exp Med 148:1523
4. + helper cell requirement in cytotoxic T lymphocyte responses Eur J Immunol 18 219
5. Buller, R. M , Holmes, K L , Hugin, A , Frederickson, T N and Morse, I. H 1987 Induction of cytotoxic T-cell responses in vivo in the absence of CD4 helper cells. Nature 328:77
6. + T cell subsets in the control of an acute Herpes simplex virus infection of the skin and nervous system J Gen Virol 68:825
7. Robertson, M N , Spangrude, G J , Hasenkrug, K , Perry, L., Nishio, J , Wehrly, K and Chesebro, B 1992 Role and specificity of T-cell subsets in spontaneous recovery from Friend virus-induced leukemia in mice J Virol 66:3271
8. Schilham, M W., Fung, L W , Rahemtulla A , Kuendig, T. Zhang, L , Potter, J , Miller, R. G , Hengartner, H and Mak, T W 1993 Alloreactive cytotoxic T cells can develop and function in mice lacking both CD4 and CD8 Eur. J Immunol 23 1299
9. + T-cell responses Curr Biol 4 499
10. Deres, K , Schild, H , Wiesmuller, K H , Jung, G and Rammensee, H G 1989 In vivo priming of virus-specific cytotoxic T lymphocytes with synthetic lipopeptide vaccine Nature 342.561
11. Martinon, F , Gras-Masse, H , Boutillon, C , Chirat, F , Deprez, B., Guillet J G , Gomard, E , Tartar, A and Levy, J P 1992 Immunization of mice with lipopeptides bypasses the prerequiste for adjuvant immune response of BALB/c mice to human immunodeficiency virus envelope glycoprotein J Immunol. 149:3416.
12. + T cell help. J Immunol. 147:4069
13. Gao, X M., Zheng, B , Liew, F Y , Brett, S and Tite, J 1991 Priming of influenza virus-specific cytotoxic T lymphocytes in vivo by short synthetic peptides J Immunol 147 3268
14. Kast, W M , Roux, L Curren, J , Blom, H J J Voordouw, A C, Meleon, R H Kolakofsky, D. and Melief, C J M 1991. Protection against lethal Sendai virus infection by in vivo priming of virus-specific cytotoxic T lymphocytes with a free synthetic peptide Proc Natl Acad Sci USA 88:2283
15. Mutsunori, S., Pendleton, C. D , Ahlers, J , Takeshita, T , Newman, M. and Berzofsky, J A 1994 Helper-cytotoxic T lymphocyte (CTL) determinant linkage required for priming of anti-HIV CTL in vivo with peptide vaccine constructs J Immunol 152:549.
16. Schulz, M , Zinkernagel, R M. and Hengartner, H. 1991 Peptide-induced antiviral protection by cytotoxic T cells Proc Natl Acad Sci USA 88 991
17. Feltkamp M. C W , Smits, H. L. Vierboom, M P M., Minaar, R P , de Jongh, B M , Drijfhout, J W., Schegget, J T , Melief, C. J M and Kass, W M 1993. Vaccination with cytotoxtc T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells. Eur J Immunol 23:2242
18. Kast, W M , Brandt, R M P and Melief, C J M 1993 Strict peptide length is not required for the induction of cytotoxic T lymphocyte-mediated antiviral protection by peptide vaccination. Eur J Immunol 23.1189
19. Zhou, X , Abdel Motal, U M , Berg, L and Jondal, M 1992 In vivo priming of cytotoxic T lymphocyte responses in relation to in vitro up-regulation of major histocompatibility complex class I molecules by short synthetic peptides Eur J. Immunol 22:3085
20. Merrifield, R B 1986 Solid phase synthesis Science 232.341
21. Bodmer H C., Pemberton, R M , Rothbard, J B. and Askonas, B A. 1988 Enhanced recognition of a modified peptide antigen by cytotoxic T cells specific for influenza nucleoprotein Cell 52 253.
22. Perkins, D L , Lai, M Z , Smith, J A and Gefter, M L 1989. Identical peptides recognized by MHC class I- and II-restricted T cells J Exp. Med 170-279
23. Rammensee, H. G , Falk, K and Rotzschke, O 1993 Peptides naturally presented by MHC class I molecules Annu Rev Immunol 11 213
24. Townsend, A R M , Rothbard, J F M , Gotch, J , Bahadur, G, Wraith, D and McMichael, A J. 1986 The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides Cell 44 959
25. Martinon, F , Cornille, F., Gomard, E., Fournie-Zaluski, M C , Abastado, J P , Roques, B P and Levy, J P 1989. Two epitopes and one agretope map to a single HLA-A2 peptide recognized by H-2-restricted T cells J. Immunol 142 3489
26. Guillet, J G , Lai, M Z , Briner, T J , Smith, J A and Gefter M L 1986 Interaction of peptide antigen and class II major histocompatibility complex as studied by T-cell activation Nature 324.260
27. Aichele, R , Hengartner H , Zinkernagel, R. M and Schulz, M. 1990 Antiviral cytotoxic T cell response induced by in vivo priming with a free synthetic peptide J. Exp Med. 171 1815.
28. Corradin G , Etlinger, H. M and Chiller, J. M. 1977. Lymphocyte specificity to protein antigens. I. Characterization of the antigen-induced in vitro T cell-dependent proliferative response with lymph node cells from primed mice J. Immunol 119:1048.
29. Healy, F , Sire, J , Gomard, E., Yssel, H., Jordan, B. R. and Levy, J P 1988 A study of functionally active amino-acids involved in the interaction of HLA-A2 and HLA-A3 molecules with cytolytic T lymphocytes. J. Immunol. 141 2487.
30. Sauzet, J P , Deprez, B. Martinon, F., Guillet, J G. Gras-Masse, H. and Gomard. E 1994. Long-lasting anti-viral cytotoxic T lymphocytes induced in vivo with chimeric-multirestricted lipopeptides Vaccine in press
31. + T cells J Immunol 144 3980.
32. + T cells in cytotoxic T lymphocyte responses against vaccinia virus J Immunol. 142:270.
33. + T lymphocytes mediate clearance of virus and regulate the antiviral antibody response. J. Virol. 61 1867.
34. + T helper cell function in vivo differential requirement for induction of antiviral cytotoxic T-cell and antibody responses J. Virol 62.2102
35. + cells in sustaining lymphocyte proliferation during lymphocytic choriomeningitis virus infection. J. Immunol. 146:1955.
36. + cells but markedly decreased helper cell activity in mice lacking CD4 Nature 353 180
37. Sette, A , Vitiello, A , Reherman, B , Fowler, P., Nayersina, R., Kast, M , Melief, C J M , Oseroff, C , Yuan, L , Ruppert, J., Sidney, J , del Guercio, M F., Southwood, S. Kubo, R T., Chesnut, R. W , Grey, H. M. and Chisari, F. V 1994. The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes. J Immunol. 153:5586.
38. Feltkamp, M. C. W , Vierboom, M P M., Kast, W M and Melief, C. J M 1994 Efficient MHC class I-peptide binding is required but does not ensure MHC class I-restricted immunogenicity Mol. Immunol 31:1391.
39. + T lymphocytes J Immunol. 151.5993.
40. Kast, W. M., Bronkhorst, A. M., de Waal, L. P. and Melief, C. J M. 1986 Cooperation between cytotoxic and helper T lymphocytes in protection against lethal Sendai virus infection. J Exp Med 164:723.
41. Jennings, S R , Bonneau, R H , Smith, P. M., Wolcott, R. M. and Chervenak, R. 1991 CD4-positive T lymphocytes are required for the generation of the primary but not the secondary CD8-positive cytolytic T lymphocyte response to Herpes simplex virus in C57BL/6 mice. Cell Immunol. 133.234.
42. + cytotoxic T-cell responses during chronic viral infection. J. Virol 68:8056
43. Chakkalath, H R , Theodos, C M., Markowitz, J S , Grusby, M J , Glimcher, L H. and Titus, R. G 1995. Class II major histocompatibility complex-deficient mice initially control an infection with Leishmania major but succumb to the disease. J Infect Dis 171:1302.
44. + cells after a transient response to antigen. Eur J. Immunol. 23.1963
45. + helper T cells J. Exp. Med 171 1315.
46. + T cells. J. Immunol. 154:4915.
47. Chang, C.-H , Furue, M and Tamaki, K 1995 B7-1 expression of Langherans cells is up-regulated by proinflammatory cytokines, and is down-regulated by interferon-γ or by interleukin-10. Eur J Immunol 25 394