-
1
-
-
0036278164
-
Tacrolimus is a class II low-solubility high-permeability drug: The effect of P-glycoprotein efflux on regional permeability of tacrolimus in rats
-
S. Tamura, A. Ohike, R. Ibuki, G.L. Amidon, and S. Yamashita Tacrolimus is a class II low-solubility high-permeability drug: the effect of P-glycoprotein efflux on regional permeability of tacrolimus in rats J. Pharm. Sci. 91 3 2002 719 729
-
(2002)
J. Pharm. Sci.
, vol.91
, Issue.3
, pp. 719-729
-
-
Tamura, S.1
Ohike, A.2
Ibuki, R.3
Amidon, G.L.4
Yamashita, S.5
-
2
-
-
0033863123
-
Effect of intestinal P-glycoprotein on daily tacrolimus trough level in a living-donor small bowel recipient
-
S. Masuda, S. Uemoto, T. Hashida, Y. Inomata, K. Tanaka, and K. Inui Effect of intestinal P-glycoprotein on daily tacrolimus trough level in a living-donor small bowel recipient Clin. Pharmacol. Ther. 68 1 2000 98 103
-
(2000)
Clin. Pharmacol. Ther.
, vol.68
, Issue.1
, pp. 98-103
-
-
Masuda, S.1
Uemoto, S.2
Hashida, T.3
Inomata, Y.4
Tanaka, K.5
Inui, K.6
-
3
-
-
0031718440
-
Effects of intestinal and hepatic metabolism on the bioavailability of tacrolimus in rats
-
Y. Hashimoto, H. Sasa, M. Shimomura, and K. Inui Effects of intestinal and hepatic metabolism on the bioavailability of tacrolimus in rats Pharm. Res. 15 10 1998 1609 1613
-
(1998)
Pharm. Res.
, vol.15
, Issue.10
, pp. 1609-1613
-
-
Hashimoto, Y.1
Sasa, H.2
Shimomura, M.3
Inui, K.4
-
4
-
-
0033326585
-
P-glycoprotein and drug therapy in organ transplantation
-
A. Lo, and G.J. Burckart P-glycoprotein and drug therapy in organ transplantation J. Clin. Pharmacol. 39 10 1999 995 1005
-
(1999)
J. Clin. Pharmacol.
, vol.39
, Issue.10
, pp. 995-1005
-
-
Lo, A.1
Burckart, G.J.2
-
5
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
S. Hoffmeyer, O. Burk, O. von Richter, H.P. Arnold, J. Brockmoller, and A. Johne Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo Proc. Natl. Acad. Sci. U. S. A. 97 7 2000 3473 3478
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, Issue.7
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
Arnold, H.P.4
Brockmoller, J.5
Johne, A.6
-
6
-
-
0034971274
-
The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells
-
M. Hitzl, S. Drescher, H. van der Kuip, E. Schafeller, J. Fischer, and M. Schwab The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells Pharmacogenetics 11 4 2001 293 298
-
(2001)
Pharmacogenetics
, vol.11
, Issue.4
, pp. 293-298
-
-
Hitzl, M.1
Drescher, S.2
Van Der Kuip, H.3
Schafeller, E.4
Fischer, J.5
Schwab, M.6
-
7
-
-
0034744113
-
No influence of the MDR-1 C3435T polymorphism or a CYP3A4 promoter polymorphism (CYP3A4-V allele) on dose-adjusted cyclosporin a trough concentrations or rejection incidence in stable renal transplant recipients
-
N. von Ahsen, M. Richter, C. Grupp, B. Ringe, M. Oellerich, and V.W. Armstrong No influence of the MDR-1 C3435T polymorphism or a CYP3A4 promoter polymorphism (CYP3A4-V allele) on dose-adjusted cyclosporin A trough concentrations or rejection incidence in stable renal transplant recipients Clin. Chem. 47 6 2001 1048 1052
-
(2001)
Clin. Chem.
, vol.47
, Issue.6
, pp. 1048-1052
-
-
Von Ahsen, N.1
Richter, M.2
Grupp, C.3
Ringe, B.4
Oellerich, M.5
Armstrong, V.W.6
-
8
-
-
0035104031
-
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects
-
I. Cascorbi, T. Gerloff, A. Johne, C. Meisel, S. Hoffmeyer, and M. Schwab Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects Clin. Pharmacol. Ther. 69 3 2001 169 174
-
(2001)
Clin. Pharmacol. Ther.
, vol.69
, Issue.3
, pp. 169-174
-
-
Cascorbi, I.1
Gerloff, T.2
Johne, A.3
Meisel, C.4
Hoffmeyer, S.5
Schwab, M.6
-
9
-
-
0034997034
-
Expression of P-glycoprotein in human placenta: Relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene
-
M. Tanabe, I. Ieiri, N. Nagata, K. Inoue, S. Ito, and Y. Kanamori Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene J. Pharmacol. Exp. Ther. 297 3 2001 1137 1143
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.297
, Issue.3
, pp. 1137-1143
-
-
Tanabe, M.1
Ieiri, I.2
Nagata, N.3
Inoue, K.4
Ito, S.5
Kanamori, Y.6
-
10
-
-
0037693831
-
Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms
-
H. Zheng, S. Webber, A. Zeevi, E. Schuetz, J. Zhang, and P. Bowman Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms Am. J. Transplant 3 4 2003 477 483
-
(2003)
Am. J. Transplant
, vol.3
, Issue.4
, pp. 477-483
-
-
Zheng, H.1
Webber, S.2
Zeevi, A.3
Schuetz, E.4
Zhang, J.5
Bowman, P.6
-
11
-
-
0036729669
-
The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in pediatric heart transplant patients
-
H. Zheng, S. Webber, A. Zeevi, E. Schuetz, J. Zhang, and J. Lamba The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in pediatric heart transplant patients Hum. Immunol. 63 9 2002 765 770
-
(2002)
Hum. Immunol.
, vol.63
, Issue.9
, pp. 765-770
-
-
Zheng, H.1
Webber, S.2
Zeevi, A.3
Schuetz, E.4
Zhang, J.5
Lamba, J.6
-
12
-
-
0035071598
-
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
-
P. Kuehl, J. Zhang, Y. Lin, J. Lamba, M. Assem, and J. Schuetz Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression Nat. Genet. 27 4 2001 383 391
-
(2001)
Nat. Genet.
, vol.27
, Issue.4
, pp. 383-391
-
-
Kuehl, P.1
Zhang, J.2
Lin, Y.3
Lamba, J.4
Assem, M.5
Schuetz, J.6
-
13
-
-
0030006845
-
Bimodal distribution of renal cytochrome P450 3A activity in humans
-
B.D. Haehner, J.C. Gorski, M. Vandenbranden, S.A. Wrighton, S.K. Janardan, and P.B. Watkins Bimodal distribution of renal cytochrome P450 3A activity in humans Mol. Pharmacol. 50 1 1996 52 59
-
(1996)
Mol. Pharmacol.
, vol.50
, Issue.1
, pp. 52-59
-
-
Haehner, B.D.1
Gorski, J.C.2
Vandenbranden, M.3
Wrighton, S.A.4
Janardan, S.K.5
Watkins, P.B.6
-
14
-
-
9144245517
-
Tacrolimus dosing in adult lung transplant patients is related to cytochrome P4503A5 gene polymorphism
-
H. Zheng, A. Zeevi, E. Schuetz, J. Lamba, K. McCurry, and B.P. Griffith Tacrolimus dosing in adult lung transplant patients is related to cytochrome P4503A5 gene polymorphism J. Clin. Pharmacol. 44 2 2004 135 140
-
(2004)
J. Clin. Pharmacol.
, vol.44
, Issue.2
, pp. 135-140
-
-
Zheng, H.1
Zeevi, A.2
Schuetz, E.3
Lamba, J.4
McCurry, K.5
Griffith, B.P.6
-
15
-
-
0034987936
-
The effect of cytokine gene polymorphisms on pediatric heart allograft outcome
-
M.R. Awad, S. Webber, G. Boyle, C. Sturchioc, M. Ahmed, and J. Martell The effect of cytokine gene polymorphisms on pediatric heart allograft outcome J. Heart Lung Transplant. 20 6 2001 625 630
-
(2001)
J. Heart Lung Transplant.
, vol.20
, Issue.6
, pp. 625-630
-
-
Awad, M.R.1
Webber, S.2
Boyle, G.3
Sturchioc, C.4
Ahmed, M.5
Martell, J.6
-
16
-
-
0034655762
-
The effect of polymorphisms in tumor necrosis factor-alpha, interleukin-10, and transforming growth factor-beta1 genes in acute hepatic allograft rejection
-
A.J. Bathgate, V. Pravica, C. Perrey, G. Therapondos, J.N. Plevris, and P.C. Hayes The effect of polymorphisms in tumor necrosis factor-alpha, interleukin-10, and transforming growth factor-beta1 genes in acute hepatic allograft rejection Transplantation 69 7 2000 1514 1517
-
(2000)
Transplantation
, vol.69
, Issue.7
, pp. 1514-1517
-
-
Bathgate, A.J.1
Pravica, V.2
Perrey, C.3
Therapondos, G.4
Plevris, J.N.5
Hayes, P.C.6
-
17
-
-
0034084575
-
Transforming growth factor beta in relation to cardiac allograft vasculopathy after heart transplantation
-
T. Aziz, P. Hasleton, A.W. Hann, N. Yonan, A. Deiraniya, and I.V. Hutchinson Transforming growth factor beta in relation to cardiac allograft vasculopathy after heart transplantation J. Thorac. Cardiovasc. Surg. 119 4 Pt 1 2000 700 708
-
(2000)
J. Thorac. Cardiovasc. Surg.
, vol.119
, Issue.4 PART 1
, pp. 700-708
-
-
Aziz, T.1
Hasleton, P.2
Hann, A.W.3
Yonan, N.4
Deiraniya, A.5
Hutchinson, I.V.6
-
18
-
-
0032424870
-
Cytokine genotypes in allograft rejection: Guidelines for immunosuppression
-
I.V. Hutchinson, D. Turner, D. Sankaran, M. Awad, V. Pravica, and P. Sinnott Cytokine genotypes in allograft rejection: guidelines for immunosuppression Transplant. Proc. 30 8 1998 3991 3992
-
(1998)
Transplant. Proc.
, vol.30
, Issue.8
, pp. 3991-3992
-
-
Hutchinson, I.V.1
Turner, D.2
Sankaran, D.3
Awad, M.4
Pravica, V.5
Sinnott, P.6
-
19
-
-
0032985695
-
Cytokine gene polymorphisms and relevance to forms of rejection
-
I.V. Hutchinson, V. Pravica, C. Perrey, and P. Sinnott Cytokine gene polymorphisms and relevance to forms of rejection Transplant. Proc. 31 1-2 1999 734 736
-
(1999)
Transplant. Proc.
, vol.31
, Issue.1-2
, pp. 734-736
-
-
Hutchinson, I.V.1
Pravica, V.2
Perrey, C.3
Sinnott, P.4
-
20
-
-
0031956810
-
Influence of cytokine genotypes on allograft rejection
-
I.V. Hutchinson, D.M. Turner, D. Sankaran, M.R. Awad, and P.J. Sinnott Influence of cytokine genotypes on allograft rejection Transplant. Proc. 30 3 1998 862 863
-
(1998)
Transplant. Proc.
, vol.30
, Issue.3
, pp. 862-863
-
-
Hutchinson, I.V.1
Turner, D.M.2
Sankaran, D.3
Awad, M.R.4
Sinnott, P.J.5
-
21
-
-
0033063027
-
Cytokine gene polymorphisms predict acute graft rejection following renal transplantation
-
D. Sankaran, A. Asderakis, S. Ashraf, I.S. Roberts, C.D. Short, and P.A. Dyer Cytokine gene polymorphisms predict acute graft rejection following renal transplantation Kidney Int. 56 1 1999 281 288
-
(1999)
Kidney Int.
, vol.56
, Issue.1
, pp. 281-288
-
-
Sankaran, D.1
Asderakis, A.2
Ashraf, S.3
Roberts, I.S.4
Short, C.D.5
Dyer, P.A.6
-
22
-
-
0029815192
-
Variation in the tumor necrosis factor-alpha gene promoter region may be associated with death from meningococcal disease
-
S. Nadel, M.J. Newport, R. Booy, and M. Levin Variation in the tumor necrosis factor-alpha gene promoter region may be associated with death from meningococcal disease J. Infect. Dis. 174 4 1996 878 880
-
(1996)
J. Infect. Dis.
, vol.174
, Issue.4
, pp. 878-880
-
-
Nadel, S.1
Newport, M.J.2
Booy, R.3
Levin, M.4
-
23
-
-
0033214529
-
Hyperexpression of CD40 ligand (CD154) in inflammatory bowel disease and its contribution to pathogenic cytokine production
-
Z. Liu, S. Colpaert, G.R. D'Haens, A. Kasran, M. de Boer, and P. Rutgeerts Hyperexpression of CD40 ligand (CD154) in inflammatory bowel disease and its contribution to pathogenic cytokine production J. Immunol. 163 7 1999 4049 4057
-
(1999)
J. Immunol.
, vol.163
, Issue.7
, pp. 4049-4057
-
-
Liu, Z.1
Colpaert, S.2
D'Haens, G.R.3
Kasran, A.4
De Boer, M.5
Rutgeerts, P.6
-
24
-
-
0030942229
-
Tumour necrosis factor haplotypes and asthma
-
M.F. Moffatt, and W.O. Cookson Tumour necrosis factor haplotypes and asthma Hum. Mol. Genet. 6 4 1997 551 554
-
(1997)
Hum. Mol. Genet.
, vol.6
, Issue.4
, pp. 551-554
-
-
Moffatt, M.F.1
Cookson, W.O.2
-
25
-
-
0031453916
-
Genetic variation in the interleukin 10 gene promoter and systemic lupus erythematosus
-
M. Lazarus, A.H. Hajeer, D. Turner, P. Sinnott, J. Worthington, and W.E. Ollier Genetic variation in the interleukin 10 gene promoter and systemic lupus erythematosus J. Rheumatol. 24 12 1997 2314 2317
-
(1997)
J. Rheumatol.
, vol.24
, Issue.12
, pp. 2314-2317
-
-
Lazarus, M.1
Hajeer, A.H.2
Turner, D.3
Sinnott, P.4
Worthington, J.5
Ollier, W.E.6
-
26
-
-
0034045545
-
TNF-308A and HLA-DR3 alleles contribute independently to susceptibility to systemic lupus erythematosus
-
M.J. Rood, M.V. van Krugten, E. Zanelli, M.W. van der Linden, V. Keijsers, and G.M. Schreuder TNF-308A and HLA-DR3 alleles contribute independently to susceptibility to systemic lupus erythematosus Arthritis Rheum. 43 1 2000 129 134
-
(2000)
Arthritis Rheum.
, vol.43
, Issue.1
, pp. 129-134
-
-
Rood, M.J.1
Van Krugten, M.V.2
Zanelli, E.3
Van Der Linden, M.W.4
Keijsers, V.5
Schreuder, G.M.6
-
27
-
-
2342527023
-
Interleukin-10 production genotype protects against acute persistent rejection after lung transplantation
-
H.X. Zheng, G.J. Burckart, K. McCurry, S. Webber, J. Ristich, and A. Iacono Interleukin-10 production genotype protects against acute persistent rejection after lung transplantation J. Heart Lung Transplant. 23 5 2004 541 546
-
(2004)
J. Heart Lung Transplant.
, vol.23
, Issue.5
, pp. 541-546
-
-
Zheng, H.X.1
Burckart, G.J.2
McCurry, K.3
Webber, S.4
Ristich, J.5
Iacono, A.6
-
28
-
-
0032825148
-
Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery
-
L.Z. Benet, T. Izumi, Y. Zhang, J.A. Silverman, and V.J. Wacher Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery J. Control. Release 62 1-2 1999 25 31
-
(1999)
J. Control. Release
, vol.62
, Issue.1-2
, pp. 25-31
-
-
Benet, L.Z.1
Izumi, T.2
Zhang, Y.3
Silverman, J.A.4
Wacher, V.J.5
-
29
-
-
0029028792
-
Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
-
V.J. Wacher, C.Y. Wu, and L.Z. Benet Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy Mol. Carcinog. 13 3 1995 129 134
-
(1995)
Mol. Carcinog.
, vol.13
, Issue.3
, pp. 129-134
-
-
Wacher, V.J.1
Wu, C.Y.2
Benet, L.Z.3
-
30
-
-
0035775486
-
Pharmacogenomics: The inherited basis for interindividual differences in drug response
-
W.E. Evans, and J.A. Johnson Pharmacogenomics: the inherited basis for interindividual differences in drug response Annu. Rev. Genomics Hum. Genet. 2 2001 9 39
-
(2001)
Annu. Rev. Genomics Hum. Genet.
, vol.2
, pp. 9-39
-
-
Evans, W.E.1
Johnson, J.A.2
-
31
-
-
0035092089
-
Pharmacogenomics: A clinician's primer on emerging technologies for improved patient care
-
J.M. Rusnak, R.M. Kisabeth, D.P. Herbert, and D.M. McNeil Pharmacogenomics: a clinician's primer on emerging technologies for improved patient care Mayo Clin. Proc. 76 3 2001 299 309
-
(2001)
Mayo Clin. Proc.
, vol.76
, Issue.3
, pp. 299-309
-
-
Rusnak, J.M.1
Kisabeth, R.M.2
Herbert, D.P.3
McNeil, D.M.4
-
32
-
-
0034660560
-
Pharmacogenetics and the practice of medicine
-
A.D. Roses Pharmacogenetics and the practice of medicine Nature 405 6788 2000 857 865
-
(2000)
Nature
, vol.405
, Issue.6788
, pp. 857-865
-
-
Roses, A.D.1
-
33
-
-
0033668881
-
Advances in pharmacogenetics and pharmacogenomics
-
E.S. Vesell Advances in pharmacogenetics and pharmacogenomics J. Clin. Pharmacol. 40 9 2000 930 938
-
(2000)
J. Clin. Pharmacol.
, vol.40
, Issue.9
, pp. 930-938
-
-
Vesell, E.S.1
-
34
-
-
0035336558
-
Pharmacokinetic and prognostic significance of intestinal MDR1 expression in recipients of living-donor liver transplantation
-
T. Hashida, S. Masuda, S. Uemoto, H. Saito, K. Tanaka, and K. Inui Pharmacokinetic and prognostic significance of intestinal MDR1 expression in recipients of living-donor liver transplantation Clin. Pharmacol. Ther. 69 5 2001 308 316
-
(2001)
Clin. Pharmacol. Ther.
, vol.69
, Issue.5
, pp. 308-316
-
-
Hashida, T.1
Masuda, S.2
Uemoto, S.3
Saito, H.4
Tanaka, K.5
Inui, K.6
-
35
-
-
0032950954
-
P-glycoprotein protects leukemia cells against caspase-dependent, but not caspase-independent, cell death
-
R.W. Johnstone, E. Cretney, and M.J. Smyth P-glycoprotein protects leukemia cells against caspase-dependent, but not caspase-independent, cell death Blood 93 3 1999 1075 1085
-
(1999)
Blood
, vol.93
, Issue.3
, pp. 1075-1085
-
-
Johnstone, R.W.1
Cretney, E.2
Smyth, M.J.3
-
36
-
-
0030883666
-
Conclusions of the corneal transplant follow up study
-
Collaborating surgeons W.J.
-
A. Vail, S.M. Gore, B.A. Bradley, D.L. Easty, C.A. Rogers, W.J. Armitage Collaborating surgeons Conclusions of the corneal transplant follow up study Br. J. Ophthalmol. 81 8 1997 631 636 [see comment]
-
(1997)
Br. J. Ophthalmol.
, vol.81
, Issue.8
, pp. 631-636
-
-
Vail, A.1
Gore, S.M.2
Bradley, B.A.3
Easty, D.L.4
Rogers, C.A.5
Armitage6
-
37
-
-
0023614199
-
Age-associated decline in cardiac allograft rejection
-
D.G. Renlund, E.M. Gilbert, J.B. O'Connell, W.A. Gay Jr., K.W. Jones, and N.A. Burton Age-associated decline in cardiac allograft rejection Am. J. Med. 83 3 1987 391 398
-
(1987)
Am. J. Med.
, vol.83
, Issue.3
, pp. 391-398
-
-
Renlund, D.G.1
Gilbert, E.M.2
O'Connell, J.B.3
Gay Jr., W.A.4
Jones, K.W.5
Burton, N.A.6
-
38
-
-
0032572694
-
Age and liver transplantation: A report of the liver transplantation database
-
R.K. Zetterman, S.H. Belle, J.H. Hoofnagle, S. Lawlor, Y. Wei, and J. Everhart Age and liver transplantation: a report of the liver transplantation database Transplantation 66 4 1998 500 506
-
(1998)
Transplantation
, vol.66
, Issue.4
, pp. 500-506
-
-
Zetterman, R.K.1
Belle, S.H.2
Hoofnagle, J.H.3
Lawlor, S.4
Wei, Y.5
Everhart, J.6
-
39
-
-
0035077028
-
Elderly transplant recipients may require less immunosuppression
-
B.A. Bradley, S. Takemoto, D. Gjertson, E. Reed, and M. Cecka Elderly transplant recipients may require less immunosuppression Transplant. Proc. 33 1-2 2001 1115 1116
-
(2001)
Transplant. Proc.
, vol.33
, Issue.1-2
, pp. 1115-1116
-
-
Bradley, B.A.1
Takemoto, S.2
Gjertson, D.3
Reed, E.4
Cecka, M.5
-
40
-
-
0027412147
-
Lung transplantation in patients over the age of 50
-
G.I. Snell, A. De Hoyos, T. Winton, and J.R. Maurer Lung transplantation in patients over the age of 50 Transplantation 55 3 1993 562 566
-
(1993)
Transplantation
, vol.55
, Issue.3
, pp. 562-566
-
-
Snell, G.I.1
De Hoyos, A.2
Winton, T.3
Maurer, J.R.4
-
41
-
-
0032533678
-
Cytokine gene polymorphisms associating with severe acute graft-versus-host disease in HLA-identical sibling transplants
-
P.G. Middleton, P.R. Taylor, G. Jackson, S.J. Proctor, and A.M. Dickinson Cytokine gene polymorphisms associating with severe acute graft-versus-host disease in HLA-identical sibling transplants Blood 92 10 1998 3943 3948
-
(1998)
Blood
, vol.92
, Issue.10
, pp. 3943-3948
-
-
Middleton, P.G.1
Taylor, P.R.2
Jackson, G.3
Proctor, S.J.4
Dickinson, A.M.5
|