In vitro gene transfer efficacies of N,N-dialkylpyrrolidinium chlorides: A structure-activity investigation

Journal of Medicinal Chemistry

Volumn 48, Issue 11, 2005, Pages 3784-3795

  Majeti, Bharat Kumar ^a   Karmali, Priya Prakash ^a   Reddy, B Surendar ^a   Chaudhuri, Arabinda ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; CATION; CHLORIDE; DEOXYRIBONUCLEASE I; DIOLEOYLPHOSPHATIDYLCHOLINE; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; DNA; HYDROXYL GROUP; LIPID; N,N DI N HEXADECYL 3,4 DI TERT BUTYLOXYCARBONYLAMINOPYRROLIDINIUM CHLORIDE; N,N DI N HEXADECYL 3,4 DIAMINOPYRROLIDINIUM CHLORIDE; N,N DI N OCTADECYL 3,4 DI TERT BUTYLOXYCARBONYLAMINOPYRROLIDINIUM CHLORIDE; N,N DI N OCTADECYL 3,4 DIAMINOPYRROLIDINIUM CHLORIDE; N,N DI N OCTADECYL N OLEYL 3,4 DI TERT BUTYLOXYCARBONYLAMINOPYRROLIDINIUM CHLORIDE; N,N DI N OCTADECYL N OLEYL 3,4 DIAMINOPYRROLIDINIUM CHLORIDE; N,N DI N TETRADECYL 3,4 DI TERT BUTYLOXYCARBONYLAMINOPYRROLIDINIUM CHLORIDE; N,N DI N TETRADECYL 3,4 DIAMINOPYRROLIDINIUM CHLORIDE; OLEIC ACID; PYRROLIDINE DERIVATIVE; PYRROLIDINIUM CHLORIDE; STEARIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LINE; CELL STRAIN COS1; CELL STRAIN HEK293T; CELL STRAIN MCF 7; CONTROLLED STUDY; DNA BINDING; DNA DEGRADATION; DRUG SENSITIVITY; DRUG SYNTHESIS; EMBRYO; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PRECURSOR; STOICHIOMETRY; STRUCTURE ACTIVITY RELATION;

ANIMALS; BETA-GALACTOSIDASE; CATIONS; CELL LINE; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CRICETINAE; CRICETULUS; DEOXYRIBONUCLEASE I; DNA; GENE TRANSFER TECHNIQUES; GENES, REPORTER; HUMANS; KIDNEY; LIPIDS; LIPOSOMES; NANOSTRUCTURES; PYRROLIDINES; QUATERNARY AMMONIUM COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 20144374476     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050128x     Document Type: Article

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