Competition for p300 regulates transcription by estrogen receptors and nuclear factor-κB in human coronary smooth muscle cells

Circulation Research

Volumn 87, Issue 11, 2000, Pages 1006-1011

  Speir, Edith ^a,b   Yu, Zu Xi ^a   Takeda, Kazuyo ^a   Ferrans, Victor J ^a   Cannon III, Richard O ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Estrogen receptors a ; Intercellular adhesion molecule 1; Nuclear factor B; Transcriptional coactivator p300; Vascular smooth muscle cells

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LIGAND; PROTEIN P300; SYNAPTOTAGMIN;

ARTICLE; ATHEROGENESIS; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; FEMALE; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; INFLAMMATION; LIGAND BINDING; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; REPORTER GENE; SMOOTH MUSCLE FIBER; TRANSCRIPTION REGULATION;

EID: 0034711483     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.87.11.1006     Document Type: Article

References (21)

1. Intemational consensus conference on postmenopausal therapy and the cardiovascular system
2. Effect of 17β-estradiol on cytokine-induced endothelial cell adhesion molecule expression
3. The nuclear receptor superfamiiy: The second decade
4. Characterization of mechanisms involved in transrepression of NF-κB by activated glucocorticoid receptors
5. The NF-κB, and I κB proteins: New discoveries and insights
6. Potential role of human cytomegalovims and p53 interaction in coronary restenosis
7. Aspirin attenuates cytomegalovirus infectivity and gene expression mediated by cyclooxygenase-2 in coronary artery smooth muscle cells
8. Human cytomegalovirus and atherogenesis
9. Cloning and characterization of the 5'-transcriptional regulatory region of the human intercellular adhesion molecule 1 gene
10. Coronary artery and cultured aortic smooth muscle cells express mRNA for both the classical estrogen receptor and the newly described estrogen receptor beta
11. Differences in protein kinase C and estrogen receptor alpha, beta expression and signaling correlate with apoptotic sensitivity of MCF-7 breast cancer cell variants
12. Antioxidant effect of estrogen on cytomegalovirus-induced gene expression in coronary artery smooth muscle cells
13. p300 is a component of an estrogen receptor coactivator complex
14. Regulation of NF-6B by cyclin-dependent kinases associated with the p300 coactivator
15. Estrogen synthesis, estrogen metabolism, and functional estrogen receptors in rat arterial smooth muscle cells in culture
16. Calcifying subpopulation of bovine aortic smooth muscle cells is responsive to 17β-estradiol
17. p300 mediates functional synergism between AF-1 and AF-2 of estrogen receptor alpha and beta by interacting directly with the N-terminal A/B domains
18. The protective Effects of estrogen on the cardiovascular system
19. Estradiol enhances leukocyte binding to tumor necrosis factor (TNF)-stimulated endothelial cells via an increase in TNF-induced adhesion molecules E-selectin, intercellular adhesion molecule type-1, and vascular cell adhesion molecule type-1
20. Constitutive activation of NF-6B during progression of breast cancer to hormone-independent growth
21. Role of CBP/P300 in nuclear receptor signaling