Molecular characterisation of two human cancer cell lines selected in vitro for their chemotherapeutic drug resistance to ET-743

European Journal of Cancer

Volumn 41, Issue 2, 2005, Pages 323-333

  Marchini, S ^a   Marrazzo, E ^a   Bonomi, R ^a   Chiorino, G ^b   Zaffaroni, M ^a   Weissbach, L ^c   Hornicek, F J ^c   Broggini, M ^a   Faircloth, G T ^d   D'Incalci, M ^a  

^a Molecular Pharmacology Unit   (Italy)

^b Fondo Edo Tempia   (Italy)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d PharmaMar USA Inc   (United States)

Author keywords

Drug resistant cells; ET 743; Microarrays

Indexed keywords

CISPLATIN; DOXORUBICIN; PACLITAXEL; TRABECTEDIN;

ARTICLE; CANCER; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CHONDROSARCOMA; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG UPTAKE; GENE EXPRESSION; HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; NUCLEOTIDE SEQUENCE; OVARY CANCER; PRIORITY JOURNAL; UNINDEXED SEQUENCE;

ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, ALKYLATING; CELL LINE, TUMOR; CHONDROSARCOMA; DIOXOLES; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; ISOQUINOLINES; OVARIAN NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, NEOPLASM; TETRAHYDROISOQUINOLINES;

EID: 19944433584     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2004.10.021     Document Type: Article

References (40)

1. Y. Guan, R. Sakai, and K.L. Rinehart Molecular and crystal structures of ecteinascidins: potent antitumour compounds from the Caribbean tunicate Ecteinascidia turbinata J Biomol Struct Dyn 10 1993 793 818
2. M. D'Incalci, E. Erba, and G. Damia Unique features of the mode of action of ET-743 Oncologist 7 2002 210 216
3. G. Valoti, M.I. Nicoletti, and A. Pellegrino Ecteinascidin-743, a new marine natural product with potent antitumour activity on human ovarian carcinoma xenografts Clin Cancer Res 4 8 1998 1977 1983
4. E. Izbicka, R. Lawrence, and E. Raymond In vitro antitumour activity of the novel marine agent, ecteinascidin-743 (ET-743, NSC-648766) against human tumours explanted from patients Ann Oncol 9 9 1998 981 987
5. E. Erba, D. Bergamaschi, and L. Bassano Ecteinascidin-743 (ET-743), a natural marine compound, with a unique mechanism of action Eur J Cancer 37 1 2001 97 105
6. H.R. Hendriks, H.H. Fiebig, and R. Giavazzi High antitumour activity of ET743 against human tumour xenografts from melanoma, non-small-cell lung and ovarian cancer Ann Oncol 10 10 1999 1233 1240
7. A. Le Cesne, J. Blay, and I. Judson ET-743 is an active drug in adult soft-tissue sarcoma (STS): a STBSG-EORTC phase II trial Proc Am Soc Clin Oncol 20 2001 353a
8. G.D. Demetri, J. Manola, and D. Harmon Ecteinascidin-743 (ET-743) induces durable responses and promising 1-year survival rates in soft tissue sarcomas (STS): final results of phase II and pharmacokinetic studies in the USA Proc Am Soc Clin Oncol 20 2001 352a
9. G.D. Demetri ET-743: the US experience in sarcomas of soft tissues Anticancer Drugs 13 Suppl. 1 2002 S7 S9
10. M. D'Incalci, and J. Jimeno Preclinical and clinical results with the natural marine product ET-743 Expert Opin Investig Drugs 12 11 2003 1843 1853
11. J.M. Jimeno, G. Faircloth, and L. Cameron Progress in the acquisition of new marine-derived anticancer compounds: development of ecteinascidin-743 (ET-743) Drugs Fut 21 1996 1155 1165
12. Y. Pommier, G. Kohlhagen, and C. Bailly DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumour compound from the caribbean tunicate Ecteinascidia turbinata Biochemistry 35 1996 13303 13309
13. G. Damia, S. Silvestri, and L. Carrassa Unique pattern of ET-743 activity in different cellular systems with defined deficiencies in DNA-repair pathways Int J Cancer 92 4 2001 583 588
14. Y. Takebayashi, F. Goldwasser, and Y. Urasaki Ecteinascidin 743 induces protein-linked DNA breaks in human colon carcinoma HCT116 cells and is cytotoxic independently of topoisomerase I expression Clin Cancer Res 7 1 2001 185 191
15. S. Jin, B. Gorfajn, and G. Faircloth Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation Proc Natl Acad Sci USA 97 12 2000 6775 6779
16. M. Minuzzo, S. Marchini, and M. Broggini Interference of transcriptional activation by the anti-neoplastic drug ET-743 Proc Natl Acad Sci USA 97 2000 6780 6784
17. Y. Takebayashi, P. Pourquier, and D.B. Zimonjic Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair Nat Med 7 8 2001 961 966
18. L. Shao, J. Kasanov, and F.J. Hornicek Ecteinascidin-743 drug resistance in sarcoma cells: transcriptional and cellular alterations Biochem Pharmacol 66 12 2003 2381 2395
19. T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J Immunol Methods 65 1-2 1983 55 63
20. C.A. Ball, G. Sherlock, and H. Parkinson Standards for microarray data Science 298 5593 2002 539
21. S. Dudoit, R.C. Gentleman, and J. Quackenbush Open source software for the analysis of microarray data Biotechniques Suppl. 2003 45 51
22. W.S. Cleveland, and R. Guarino The use of numerical and graphical statistical methods in the analysis of data on learning to see complex random-dot stereograms Perception 7 1 1978 113 118
23. J. Quackenbush Microarray data normalization and transformation Nat Genet 32 Suppl 2002 496 501
24. M.B. Eisen, P.T. Spellman, and P.O. Brown Cluster analysis and display of genomewide expression patterns Proc Natl Acad Sci USA 95 25 1998 14863 14868
25. D. Belotti, M. Rieppi, and M.I. Nicoletti Paclitaxel (Taxol(R)) inhibits motility of paclitaxel-resistant human ovarian carcinoma cells Clin Cancer Res 2 10 1996 1725 1730
26. M.L. Amador, J. Jimeno, and L. Paz-Ares Progress in the development and acquisition of anticancer agents from marine sources Ann Oncol 14 11 2003 1607 1615
27. G. Schwartsmann, A. Brondani da Rocha, and R.G. Berlinck Marine organisms as a source of new anticancer agents Lancet Oncol 2 4 2001 221 225
28. C. van Kesteren, M.M. de Vooght, and L. Lopez-Lazaro Yondelis (trabectedin, ET-743): the development of an anticancer agent of marine origin Anticancer Drugs 14 7 2003 487 502
29. M. Casanova, P. Casali, and C. Sessa Phase II study of 3-Hours infusion Ecteinascidin-743 (ET-743)in pretreated adult and pediatric patients with advanced or recurrent sarcomas: preliminary results Proc SIOP 257 2002
30. S. Delaloge, A. Yovine, and A. Taamma Ecteinascidin-743: a marine-derived compound in advanced, pretreated sarcoma patients - preliminary evidence of activity J Clin Oncol 19 5 2001 1248 1255
31. Forouzeh B, Hildago M, Denis L, et al. Phase I and pharmacokinetic study of the marine-derived DNA minor groove binder ET-743 on a weekly x3 every-4-week schedule in patients with advanced solid malignancies. In: Proceedings of AACRNCI-EORTC International Conference on Molecul targets and cancer therapeutics: Discovery, Biology and Clinical applications. Miami Beach, October 29-November 2, 2001, p. 42
32. G. Grasselli, A. Malossi, and N. Colombo Phase I and pharmacokinetic (PK) study of ecteinascidin-743 (ET, Trabectedin) and cisplatin (P) combination in pre-treated patients (pts) with selected advanced solid tumours Proc Am Soc Clin Oncol 22 2003 135
33. Y. Kuwazuru, A. Yoshimura, and S. Hanada Expression of the multidrug transporter, P-glycoprotein, in chronic myelogenous leukaemia cells in blast crisis Br J Haematol 74 1 1990 24 29
34. Y. Kuwazuru, A. Yoshimura, and S. Hanada Expression of the multidrug transporter, P-glycoprotein, in acute leukemia cells and correlation to clinical drug resistance Cancer 66 5 1990 868 873
35. L.J. Goldstein, H. Galski, and A. Fojo Expression of a multidrug resistance gene in human cancers J Natl Cancer Inst 81 2 1989 116 124
36. A. Kanzaki, Y. Takebayashi, and X.Q. Ren Overcoming multidrug drug resistance in P-glycoprotein/MDR1-overexpressing cell lines by ecteinascidin 743 Mol Cancer Ther 1 14 2002 1327 1334
37. M. Garcia-Rocha, M.D. Garcia-Gravalos, and J. Avila Characterisation of antimitotic products from marine organisms that disorganise the microtubule network: ecteinascidin 743, isohomohalichondrin-B and LL-15 Br J Cancer 73 8 1996 875 883
38. K.B. Hotary, E.D. Allen, and P.C. Brooks Membrane type I matrix metalloproteinase usurps tumour growth control imposed by the three-dimensional extracellular matrix Cell 114 1 2003 33 45
39. K. Watanabe, T. Ozaki, and T. Nakagawa Physical interaction of p73 with c-Myc and MM1, a c-Myc-binding protein, and modulation of the p73 function J Biol Chem 277 17 2002 15113 15123
40. H.B. Deng, H.K. Parekh, and K.C. Chow Increased expression of dihydrodiol dehydrogenase induces resistance to cisplatin in human ovarian carcinoma cells J Biol Chem 277 17 2002 15035 15043